Hep B Blog

The Drug Discovery Process

It takes talent, dedication, lots of  time, and a sizable investment to bring a safe and effective drug to market. The Drug Discovery Process YouTube video, compliments of PhRMAPress, introduces the long and arduous drug process from the identification of a compound in the lab, though clinical trials and the FDA approval process. It may sound simple, but this process may take up to 1,000 people, 12-15 years and up to 1.3 to 1.6 billion dollars to put a new drug in the hands of the patient.

Consider this process when following the progress of  hepatitis B drugs on the Hepatitis B Foundation Drug Watch page.  Compounds could remain in various stages for years. Note that the “preclinical” phase represents the drugs that are still in the lab and not yet ready for human clinical trials.

The Hepatitis B Foundation also maintains a webpage with the latest hepatitis B related clinical trials. Contact information is provided for each trial for those wishing to volunteer to participate.  Volunteers must meet the criteria for participation in a trial.

The future looks bright for a functional cure for hepatitis B. It may take a few more years to get the drug into the hands of the patient, but each step of the process is crucial in order to produce a drug that is both effective and safe.




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2 thoughts on “The Drug Discovery Process”

  1. I was on anti-viral medication for hepatitis treatment for 15 months, have done my HBV DNA test- results- HBV DNA Qualification-COBAS TaqMan -Below 20 IU/ml- Log Value not applicable. Have also done Liver Function Test-Results – Perfect, but I still tested to HBV last December 2014. The HBV DNA Test and LFT test were done January 2015 after 12 months on medication. I resumed medication in January 2015. But have stop two months ago. What should I do?

    1. Hello David, From what you wrote, it appeared that your antiviral medication worked well for you while you took it. It reduced your viral load and your liver function test showed no liver damage. I’m not sure why you stopped taking it. Unless you have taken antivirals for several years, and test negative for viral load and even the hepatitis B surface antigen for at least one or more years, you should probably stay on antivirals. Stopping antiviral treatment can cause your viral load to climb again and may cause liver damage. I’d suggest you consult carefully with your doctor before going off them, considering they seemed to be working. I may be missing some information. Thanks.

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