Professional Liver Disease Resources and Statements
AASLD has released an expert panel consensus statement “Vaccines to prevent COVID-19 infection in patients with liver disease.” They also have a robust patient resource page, offering information and webinars for people with viral hepatitis and liver disease.
EASL has released a policy statement on COVID-19 vaccination for people with liver disease or liver transplantation. EASL also has a webpage with internal and external resources and published a position paper in August 2020, “Impact of COVID-19 on the care of patients with liver disease.”
COVID-19 Vaccine Information Resources
- CDC mRNA Vaccine Overview
- CDC Vaccine Development and Rollout
- Information Pfizer Vaccine
- Information on Moderna Vaccine
- Information on Janssen/J&J Vaccine
- Information on AstraZeneca Vaccine
- Global Vaccine Tracker of All COVID-19 Vaccines in Clinical Trial and Approved
Research Studies on COVID-19 and Liver Disease
- Marjot T, Webb GJ, Barritt AS 4th, Moon AM, Stamataki Z, Wong VW, Barnes E. COVID-19 and liver disease: mechanistic and clinical perspectives. Nature Reviews Gastroenterology & Hepatology 2021 Mar 10:1–17. doi: 10.1038/s41575-021-00426-4. Epub ahead of print. https://www.nature.com/articles/s41575-021-00426-4
- Chen L, Huang S, Yang J, Cheng X, Shang Z, Lu H, Cheng J. Clinical characteristics in patients with SARS-CoV-2/HBV co-infection. Journal of Viral Hepatitis 2020 Dec;27(12):1504-1507. Epub 2020 Aug 16. https://onlinelibrary.wiley.com/doi/full/10.1111/jvh.13362
- Chen X, Jiang Q, Ma Z, Ling J, Hu W, Cao Q, Mo P, Yao L, Yang R, Gao S, Gui X, Hou W, Xiong Y, Li J, Zhang Y. Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection. Virologica Sinica 2020 Aug 24:1–4. Epub ahead of print. https://link.springer.com/article/10.1007/s12250-020-00276-5
- Lin Y, Yuan J, Long Q, Hu J, Deng H, Zhao Z, Chen J, Lu M, Huang A. Patients with SARS-CoV-2 and HBV co-infection are at risk of greater liver injury. Genes & Diseases 2020 Nov 18. Epub ahead of print. https://www.sciencedirect.com/science/article/pii/S2352304220301367
- Liu J, Wang T, Cai Q, Sun L, Huang D, Zhou G, He Q, Wang FS, Liu L, Chen J. Longitudinal changes of liver function and hepatitis B reactivation in COVID-19 patients with pre-existing chronic hepatitis B virus infection. Hepatology Research 2020 Nov;50(11):1211-1221. Epub 2020 Aug 29. https://onlinelibrary.wiley.com/doi/full/10.1111/hepr.13553
- Liu R, Zhao L, Cheng X, Huan H, Li C, Li D, Liu A, Gao G, Zhou F, Liu F, Jiang Y, Zhu C, Xia Y. Clinical Characteristics of COVID-19 Patients with Hepatitis B Virus Infection - a Retrospective Study. Liver International 2020 Dec 22. Epub ahead of print. https://onlinelibrary.wiley.com/doi/10.1111/liv.14774
- Rodríguez-Tajes S, Miralpeix A, Costa J, López-Suñé E, Laguno M, Pocurull A, Lens S, Mariño Z, Forns X. Low risk of hepatitis B reactivation in patients with severe COVID-19 who receive immunosuppressive therapy. Journal of Viral Hepatitis 2021 Jan;28(1):89-94. Epub 2020 Oct 12. https://onlinelibrary.wiley.com/doi/10.1111/jvh.13410
- Zou X, Fang M, Li S, Wu L, Gao B, Gao H, Ran X, Bian Y, Li R, ShanshanYu, Ling J, Li D, Tian D, Huang J. Characteristics of Liver Function in Patients With SARS-CoV-2 and Chronic HBV Coinfection. Clinical Gastroenterology and Hepatology 2020 Jun 15:S1542-3565(20)30821-1. Epub ahead of print. https://www.sciencedirect.com/science/article/abs/pii/S1542356520308211
- The World Hepatitis Alliance has a hub of resources for those living with viral hepatitis and are concerned with the impact COVID-19 has on their health and access to testing and treatment services.
- The U.S. Centers for Disease Control and Prevention (CDC) has an informational page: What You Need to Know About Liver Disease and COVID-19
- Hepatitis Australia - A timely fact sheet with Information about COVID-19 for people living with chronic HBV and HCV has been posted by a coalition of organizations in Australia called Hepatitis Australia.
- Hepatitis B and C Virus Considerations in COVID-19, Infectious Disease Advisor - 7/15/20
- Hep B and COVID-19: Resources for Individuals and Healthcare Workers, Hepatitis B Foundation Blog, 4/8/20
What We Are Doing
The Hepatitis B Foundation is rapidly responding to requests for information from people around the world living with hepatitis B. We continue to take phone, email and social media requests to help people with hepatitis B and liver disease make informed decisions about COVID-19 vaccination. We are trying to provide the latest information and data, so please check this website often for new updates, or contact us if you have specific questions. We are also proactively advocating for our communities. In February 2021, we started an advocacy campaign, including a public statement and online petition, urging companies with clinical trials for COVID-19 vaccines to include people with hepatitis B and liver disease, and to make sub-group data publicly available. To include your voice, you can sign this petition now!
Out of an abundance of caution, and in line with state and federal recommendations, the Hepatitis B Foundation staff is currently teleworking indefinitely and monitoring the COVID-19 situation daily. We are 100% business as usual, with a few notable exceptions:
- We are restricting visitors to our physical location and following all state and federal recommendations to keep our staff and community healthy.
- We are postponing all community events and switching scheduled in-person meetings to remote when possible.
- We are still responding to telephone calls to our helpline, but you will need to leave a voice message at 215-489-4900. We will return your call as soon as we can. During this time, it is best to email your hepatitis B questions to the helpline at firstname.lastname@example.org.
We recommend that you follow guidelines from the U.S. Centers for Disease Control and Prevention to keep you, your family and your community safe.
Finally, you might find interesting this message from Dr. Timothy Block, Hepatitis B Foundation President.