Currently there is only one approved treatment for HDV. Pegylated interferon alpha is the only drug that has been shown to be somewhat effective against the virus and it acts by stimulating the body's immune system to fight the virus. A small percentage (<30%) experience remission when injected weekly over 48 weeks or longer. Oral nucleosides approved for hepatitis B have been used for HDV if interferon therapy is not possible and there is a high hepatitis B viral load. But these have not been very effective.

Currently, there is more hope for people diagnosed with Hepatitis D with promising new drugs in development. For more information about these new drugs, visit our drug watch page.