34. What is the treatment algorithm for patients with HBeAg positive compensated disease?

So here is the algorithm that we published in the paper. You have a patient that’s e-Positive, we look at the DNA. If the DNA is less than 10 to the fifth, then probably that patient can be followed because they have inactive disease. If the DNA is greater or equal to 10 to the fifth then we look at the ALT. If the ALT is normal, that’s probably immune tolerant, now you can consider a biopsy, but most of us would do serial laboratory testing because this is probably immune tolerant. But if the ALT is elevated, then these are candidates for either of the first line therapies.