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Diabetes Identified as Risk Factor for Liver Cancer Across Ethnic Groups
Dec 16 – Diabetes was associated with an increased risk for developing hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans. Read more.
Genetic Flaw in Males Triggers Onset of Liver Cancer, Diabetes
Dec 16 – Michigan State University researchers have uncovered a genetic deficiency in males that can trigger the development of one of the most common types of liver cancer and type 2 diabetes. Read more.
Universalization of Hepatitis B Vaccination Would be Taken Up with the Centre
Dec 16 – The Indian Society of Gastroenterology is appealing to the Union Health Ministry with the intent of universalizing the hepatitis B vaccine across all sections of the country. Read more.
About 2 Percent of Iranian Population Suffers from Hepatitis B
Dec 16 – About 1.4 million Iranians suffer from Hepatitis B, which indicates the average prevalence of the disease is about 2 percent. At the same time, the number of people infected with hepatitis B is declining. Read more.
Tenofovir for Hepatitis B Remains Safe and Effective Over 7 Years
Dec 9 – Chronic hepatitis B patients treated with tenofovir (Viread) for 7 years continued to maintain viral suppression and liver enzyme normalization, while serological response rates continued to increase, according to a poster presented at AASLD 2013. Read more.
China's Struggle With Hepatitis B Discrimination
Dec 9 – Despite a 2010 law banning hepatitis B screening in job and school admission applications, HBV discrimination abounds in China, and seeking justice remains a challenge. Read more.
Peru: Liver Cancer Like No Other
Dec 9 – Liver cancer is the sixth most common cancer worldwide, most often affecting men over 40, and those with cirrhosis or hepatitis B or C. But in Peru, it also uncharacteristically affects young people who do not have the identified related risk factors. Read more.
Warnings for Hepatitis B Reactivation in Cancer Patients Welcomed by the AASLD
Dec 2 – The FDA announced the requirement of a Boxed Warning for the anti-cancer immunosuppressive drugs Arzerra (ofatumumab) and Rituxan (rituximab), and is specific to the risk of reactivating hepatitis B in patients who were previously infected with the virus. Read more.
Arrowhead Submits Phase 2a Application for Hep B RNAi Candidate
Dec 2 – After announcing promising new data, Arrowhead has submitted its application to begin a phase II-a trial of ARC-520. Researchers will look to determine the effect of one intravenous dose of ARC-520, in combination with the oral antiviral entecavir, on hepatitis B surface antigen reduction. Read more.
Vaccine Implant Could Eliminate Painful Booster Shots
Dec 2 – Scientists in Europe have devised a novel new system that might one day replace booster shots. Patients would swallow a pill to trigger the release of vaccine doses from a gel implant placed beneath the skin. Read more.
Tenofovir Alafenamide Shows Similar Anti-HBV Activity with Less Kidney Toxicity
Nov 25 – A new formulation of tenofovir that can be taken at lower doses demonstrated potent activity against hepatitis B similar to that of the existing formulation in a 28-day study, but with less effect on kidney function, researchers reported at the 2013 AASLD Liver Meeting. Read more.
Hepatitis B and C Rates Higher Than Government Estimates
Nov 25 – A new federal government study provides the first estimates of the proportion of the population infected with the hepatitis B and C viruses, but experts say the figures significantly downplay the scale of the problem in Canada. Read more.
'Silent Epidemic' - Nearly Ten Percent of Filipinos Infected With Hepatitis
Nov 25 – Almost 10% of the Philippine population are infected with viral hepatitis, forcing experts to say that the situation is a "silent epidemic." 7.3 million are infected with chronic HBV and 1 million are infected with HCV. Read more.
B.C. Man Accused of Illegal Dentistry Turns Himself In
Nov 25 – A follow up on a British Columbia man, David Wu, accused of illegal dentistry, practicing out of his dirty, disorganized bedroom with unsterilized instruments. Most patients were young Chinese-Canadians now at risk for hepatitis B, C or HIV. Read more.
Entecavir + Tenofovir Works Well for Hepatitis B Patients with Prior Treatment Failure
Nov 18 – A dual regimen of entecavir (baraclude) plus tenofovir (Viread) for 48 weeks led to virological response and was generally well-tolerated as second-line therapy for chronic hepatitis B patients who had failed previous nucleoside/nucleotide treatment, according to data presented at the 2013 AASLD Liver Meeting. Read more.
Hepatitis B Vaccine Protection Lasts at Least 30 Years
Nov 18 – Hepatitis B vaccination provides long-term protection through 30 years for a majority of recipients, and more than 90% were protected with either initial immunization or a booster, according to a presentation at the 2013 AASLD Liver Meeting. Read more.
Genovate and ScinoPharm Co-Develop Hepatitis B Drug "Livepro"
Nov 18 – Generic drug Livepro, (Entecavir) will be commercially available in Taiwan at the end of the year and is a joint development product of Genovate and ScinoPharm. Read more.
HBV Response to Tenofovir Similar in People With and Without HIV
Nov 18 – Nearly 90% of people with chronic hepatitis B virus in a Spanish group attained an undetectable HBV load after 96 weeks of tenofovir. Response rates did not differ between people with and without HIV infection. Read more.
Hepatitis B Treatment with Entecavir or Tenofovir Lowers But Does Not Eliminiate HCC Risk
Nov 11 – While entecavir or tenofovir can reduce the risk of hepatocellular carcinoma, people with chronic hepatitis B should continue to undergo regular monitoring for liver cancer. Better predictive models may also be needed for Caucasian patients. Read more.
Early Treatment With Nucleotide/Nucleoside Analogues Safe, Effective for HBV-Induced Liver Failure
Nov 11 – Immediate treatment of hepatitis B virus induced acute liver failure with nucleotide/nucleoside analogues is well tolerated and avoids liver transplantation, researchers reported at the 2013 AASLD Liver Meeting. Read more.
Viral Hepatitis is a Leading Cause of Death Worldwide
Nov 11 – Chronic viral hepatitis was identified as one of the leading causes of mortality worldwide, according to the 2010 Global Burden of Disease Study presented at the 2013 AASLD Liver Meeting. Read more.
The Prevalence of Fibromyalgia Among Patients with Hepatitis B Virus Infection
Nov 11 – Fibromyalgia, characterized by widespread and chronic musculoskeletal pain and fatigue, appears to be more prevalent among patients with hepatitis B, according to a recent study. Read more.
Arrowhead Presents Data Suggesting ARC-520 Induces Therapeutic Flare in Chronic Hepatitis B
Nov 4 – Data presented at the AASLD Liver Meeting demonstrated a reduction of key HBV antigens and DNA and a therapeutic immunological flare, which could lead to HBsAg seroconversion and a functional cure for HBV. Read more.
Fast, Painless Alternative to Liver Biopsies for Hepatitis Patients Proves Accurate and Reliable
Nov 4 – FibroScan, a non–invasive alternative to liver biopsy, the current standard method of diagnosing cirrhosis in hepatitis patients, proves very reliable in a national multi–center. Read more.
Barber with Hepatitis B Jailed in Dubai for Offering Bribe Over Blood Test
Nov 4 – A barber with Hepatitis B and two coworkers who tried to bribe a municipality health worker into falsifying blood test results have been sentenced to one year in prison. Workers seeking work permits in the UAE are screened and deported if they are found HBV positive and intend to work with the public, including barbers and salon workers. Read more.
Researchers Recently Launched Collaborative Hepatitis Network in Africa
Nov 4 – Physicians and researchers from Africa, the United States and Europe recently launched the Africa Collaborative Hepatitis Network, known as HepNet to study how to better prevent and control viral hepatitis. Read more.
Asian Americans Comprise Half of All People with Hepatitis B in the U.S.
Oct 28 – Local hepatitis B advocates in Seattle debunk HBV myths and state we need more education to overcome stigma affecting Asian and Pacific Islanders (APIs). While APIs account for less than 5 percent of the U.S. population, they comprise half of the estimated 1.2 million people living in the United States with chronic hepatitis B. Read more.
Coffee Consumption Reduces Risk of Liver Cancer
Oct 28 – A meta-analysis of 16 studies consistently showed that a moderate amount of coffee consumption, particularly three cups a day, could possibly reduce the risk of liver cancer by 50 percent. Read more.
Scientists Find that Activating Family of Small Proteins Could Suppress Liver Malignancies
Oct 28 – Signaling crosstalk between different protein switches has an influence on the development of cancer and paves the way for the development and application of therapeutics targeted at liver cancer, according to research from the National University of Singapore. Read more.
Son Gives Dad a Liver and a New Life
Oct 28 – A son gives his father the gift of life by donating part of his liver to his father, diagnosed with liver cancer due to chronic hepatitis B diagnosed 30 years ago. Read more.
Hepatitis B Mutation Seen in Only Men, Increased Risk of Liver Cancer
Oct 21 – A team of researchers identified a mutation from the hepatitis B virus that seems to appear only in men and may explain why HBV-infected males are roughly five times more likely than HBV–infected women to develop certain types of liver cancer. Read more.
Entecavir and Tenofovir Both Work Well Against Hepatitis B in Clinical Practice
Oct 21 – Entecavir (Baraclude) and tenofovir (Viread) both demonstrated potent activity against hepatitis B virus in a Turkish study presented at the second IDWeek conference. Read more.
Hepatitis B Treatment in Real Life: Common & Uncommon Patient Profiles
Oct 21 – The Asian Health Foundation is hosting a CME/CE certified educational dinner meeting series in 6 cities across the U.S., and will provide Health Care Professionals with an understanding of treatment strategies for hepatitis B. Read more.
Arrowhead to Present at Upcoming Conferences Oct 21 Arrowhead Research Corporation will present data on ARC-520, its hepatitis B drug candidate, at two scientific conferences including the 2013 International Meeting on Molecular Biology of Hepatitis B Viruses in Shanghai, coordinated by the Hepatitis B Foundation, and the AASLD Liver Meeting in Washington, DC.Read more.
Vaccination Campaign Doubles HBV Mutations
Oct 14 – A universal infant vaccination campaign in China has led the Hepatitis B virus to more than double its rate of "breakout" mutations. These mutations may enable the virus to elude the vaccine, necessitating new vaccination strategies. Read more.
Tenofovir May Help Mother-to-Child Hepatitis B Transmission
Oct 14 – Taking tenofovir during the final months of pregnancy may provide extra protection against perinatal transmission of hepatitis B virus, along with immunization of the infant, according to a presentation at the IDWeek conference. Read more.
Arrowhead Initiates Phase 1 Study of ARC-520 for Treatment Against Chronic HBV Infection
Oct 14 – Arrowhead announced that it completed enrollment in a phase 1 clinical trial of ARC-520, its RNAi-based candidate against chronic hepatitis B. Initial data indicate that ARC-520 is generally safe and well tolerated at all six dose levels studied. Read more.
Researchers Identify Liver Cancer Progenitor Cells Before Tumors Become Visible
Oct 14 – Researchers have isolated and characterized the progenitor cells that eventually give rise to malignant hepatocellular carcinoma (HCC) tumors, according to researchers at the University of California, San Diego School of Medicine. Read more.
Hepatitis B Foundation’s Research Institute Renamed for Nobel Prize Winner Dr. Baruch S. Blumberg
Oct. 7 - The Hepatitis B Foundation officially renamed its research institute the "Baruch S. Blumberg Institute" in a grand re-opening ceremony today to honor the scientific legacy of the Foundation’s co-founder, Dr. Baruch Blumberg who won the Nobel Prize for his discovery of the hepatitis B virus. Featured guest speaker was Mr. Mark Thompson, President and CEO of The New York Times, who is also the son-in-law of the late Dr. Blumberg. Read more.
Entecavir, Tenofovir Comparable in Patients with Treatment-Naïve Chronic Hepatitis B
Oct 7 – Third-year results of a “real-world” cohort study found the antivirals entecavir and tenofovir provided comparable efficacy for treatment–naïve patients with chronic hepatitis B and high genetic barriers against resistance, a study concluded at IDWeek 2013. Read more.
High HBV Viral Load Raises Risk of Progression to Liver Cancer
Oct 7 – Hepatitis B patients with high HBV DNA levels, indicating active viral replication, are more likely to experience progression of abnormal liver nodules to hepatocellular carcinoma, researchers reported at the 7th International Liver Cancer Association Annual Conference (ILCA 2013). Read more.
HBV Vaccine Response Status Not Associated with cART CD4 Gains at 1-Year
Oct 7 – Hepatitis B virus vaccine response status was not associated with post–combination antiretroviral therapy (cART) CD4 gains at 1-year among those with virologic suppression, a study concluded at IDWeek 2013. Read more.
FDA Strengthens Hepatitis B Warning on 2 Cancer Drugs
Sept 30 – U.S. health regulators have strengthened the warnings on two blood cancer drugs to reflect the risk that they may reactivate the hepatitis B virus in patients previously infected with the disease. Read more.
Preventing Mother-to-Child Transmission of HBV
Sept 30 – Pregnant women with hepatitis B are less likely to pass the virus on to babies delivered by elective cesarean section, compared to those delivered naturally or by urgent cesarean section, according to researchers. Read more.
Published Phase 3 Data on HEPLISAV Shows Safety and Effectiveness
Sept 30 – Dynavax announced results of two Phase 3 trials of HEPLISAV published in J. Vaccine, which concluded that HEPLISAV induced significantly higher seroprotection rates in all groups (including hypo-responsive populations) than the approved HBV vaccine in a shorter 2-dose schedule over one month while maintaining a similar safety profile. Read more.
New Test Enables Early Diagnosis of Liver Cancer
Sept 23 – Researchers have found a way to make early liver cancer show its true colors. They have developed a test that will help pathologists clearly distinguish early liver cancer cells from nearly identical normal liver cells by giving them a distinctive red-brown hue. Read more.
Patient, Heal Thyself: Solution to Personalized treatment for Chronic Infections Could Lie in Patient's Own Blood
Sept 23 – There’s hope for a new personalized treatment strategy that could use a patient's own blood to treat chronic hepatitis B and C infections using vaccine therapies. Read more.
Army Recruits Dropped Over Hepatitis B, HIV/AIDS
Sept 23 - Hundreds of youth who turned up for the three-day Uganda People’s Defense Forces (UPDF) recruitment exercise in Kampala were disqualified after they tested positive for Hepatitis B or HIV/AIDS. Read more.
Age is No Deterrent in Dream to Save Lives
Sept 23 – 91-year-old Wu Mengchao is among China’s most renowned doctors in the field of liver cancer treatment and research. His drive and accomplishments are admirable. Read more.
114 Children Hospitalized After Being Given Hepatitis B Vaccine Instead of Pulse Polio Drops
Sept 16 – In a major medical goof up, as many as 114 children were hospitalized in West Bengal after they were mistakenly given Hepatitis B vaccine orally instead of Pulse Polio drops on Sunday. Read more
High Rate of New Hepatitis B Among African-Americans
Sept 16 – Black Americans have a higher incidence of hepatitis B virus infection (new infections) than any other racial/ethnic group according to a review article of Clinical Gastroenterology and Hepatology. Read more
HIV and Hepatitis Risk for Steroid Users
Sept 16 - People who inject anabolic steroids and tanning drugs are at a higher risk of HIV and viral hepatitis, a study from Public Health England (PHE) has revealed. Read more.
OSHA Fines Atlanta Health Careers Institute
Sept 16 – OSHA fined Atlanta Health Careers Institute LLC $62,000 for allegedly not training properly employees in a bloodborne pathogen program and not making available the Hepatitis B vaccine to workers exposed to potential bloodborne pathogen hazards. Read more.
Hep B Vaccination May Cut Deaths From Liver Disease
Sept 9 – Taiwanese researchers report a 90 percent reduction in deaths from complications of hepatitis B and a decrease in the spread of hepatitis B since the country began its infant vaccination program in 1984. Read more
Tenofovir is Highly Effective for HIV/HBV Co-infection, Meta-Analysis Shows
Sept 9 – Tenofovir, which has potent activity against both HIV and hepatitis B virus, is the most effective hepatitis B treatment for people with HIV and HBV co-infection, according to a 23-study meta-analysis. Read more
Cancer Experts Detail New Approaches to Liver Cancer Treatment with Stereotactic Ablative Radiotherapy
Sept 9 – Clinical experts outlined promising new approaches to treating liver cancer using radiosurgery with advanced imaging and motion management technology, since many patients are not eligible for a liver transplant or surgery. Read more.
Redistricting Might Shorten Wait for Liver Transplants
Sept 3 – Where you live can affect your chances of getting a liver transplant and your risk of dying while waiting. William Sherbert learned this lesson when liver failure from hepatitis B put him on the transplant list. Read more
Ramon Magsaysay Awards: Pinoy Doc Champions Health Care for All
Sept 3 - Filipino hepatologist and Ramon Magsaysay awardee, Dr. Enesto Domingo, discusses the challenges in addressing hepatitis B and liver cancer in the Philippines, and the need for universal HBV vaccination and health care for all. Read more
Western Australia (WA) Research Circumvents Stem Cell Cancer Risk
Sept 3 – The clinical use of multipotent stem cells to regenerate new tissue and organs may be perceived by some as the solution of the future, but is this evidence conclusive? Read more.
Smart Syringe Turns Red to Tell You It's Been Used
Sept 3 – An innovative solution to the global problem of unsterilized second-hand syringes may save thousands of lives each year by reducing the transmission of blood-borne diseases such as hepatitis B, hepatitis C, and HIV. Read more
Novel Biomarker Could Potentially Lead to Early Detection of Liver Fibrosis
August 26 – A study reveals the central role of the immune molecule interleukin 33 (IL-33) in the formation of liver fibrosis, suggesting its use as a biomarker to potentially lead to early detection of fibrosis in patients. Read more
German Surgeons Perform Liver Cancer Operation Using Tablet
August 26 – The first of its kind liver cancer operation was conducted with the help of a tablet and a new app, promising support for surgeons in reducing the rate of complications during operations. Read more.
Galectin Therapeutics Targets Silent Epidemic in Liver Fibrosis
August 26 – Galectin Therapeutics, focusing on diseases such as fatty liver disease where galectin proteins play a major role in the disease process, has developed 2 classes of galectin inhibitors. The company is currently enrolling NASH patients with advanced fibrosis in a dose escalated Phase 1 study. Read more
Call for Coalition Hep B Commitment
August 26 – Peak health bodies are calling on the Coalition to commit to funding what they say are urgently needed hepatitis B treatment and awareness programs. Read more
GAVI Alliance Bridges China-Africa Immunization Cooperation
August 19 – The GAVI Alliance held an event to share the Chinese experience of immunization with African health ministers at the China-Africa health forum, which focused on the lessons learned from China's hepatitis B vaccination program. Read more
When Vaccinations Fail to Cause Response: Causes Vary with Vaccine and Person
August 19 – Most people react very well to vaccinations and have an adequate immune response against the pathogens. However, reasons for a non-response may vary. Read why some are hepatitis B vaccine non-responders. Read more.
Increased Caffeine Intake May Reduce Fatty Liver in People With NAFLD
August 19 – Surprise! Your morning cup of tea or coffee may be doing more than just perking you up before work, suggests an international team of researchers led by Duke-NUS Graduate Medical School and the Duke University School of Medicine. Read more
Hepatitis C Outbreak: In Wake Of Kwiatkowski Guilty Plea, Patients Seek Accountability
August 19 – Patients at a New Hampshire hospital who were infected with hepatitis C by a traveling medical technician with a drug problem are pleased with his guilty plea but are still pushing to hold others accountable. Read more
New Gene Therapy Advance Holds Promise for the Treatment of the Global Killer HBV
August 12 – A new gene therapy approach based on the engineering of a new class of proteins called TALENs recognizes and may disable the DNA of HBV. Read more
End This Neglect of Viral Hepatitis
August 12 – With mortality rates comparable to HIV/Aids, TB and malaria, is it time the global health community addressed viral hepatitis with the urgency it needs? Read more.
Urgent Call to Avert Hepatitis B Crisis
August 12 – Migrant communities in Melbourne’s west are being urged to protect against hepatitis infection as experts warn that Australia faces a hepatitis B crisis. Read more
Learn From My Friend’s Death: Love Your Liver
August 12 – Reflecting on the tragic loss of a friend, this author and co-founder of the Al D. Rodriguez Liver Foundation raises viral hepatitis awareness. Screen. Vaccinate. Don't Hesitate. Read more
China Nixes Patent for Gilead HIV, Hepatitis Drug Viread
August 5 – China officials have revoked the patent protecting Gilead Sciences Inc.'s HIV and hepatitis B drug, Viread. What does this mean for those living with chronic hepatitis B? Read more
Hepatitis B Treatment with Entecavir Lowers Risk of Liver Cancer
August 5 – Long-term treatment with entecavir significantly reduces the chances of developing hepatocellular carcinoma compared with no treatment, and appears to lower the risk more than an older drug, especially for the most at-risk patients, according to a report in the July 2013 issue of Hepatology. Read more.
Boston Patients Exposed to Virus Due to Lack of EHR Training
August 5 – Thirteen dialysis patients at Boston Medical Center were exposed to hepatitis B earlier this year when two nurses from an outside dialysis contractor failed to receive access to the hospital’s EHR system, which would have let them know that an infected patient had used equipment that was then shared with the victims. Read more
'Two-Thirds of Injections in India Unsafe’
August 5 – Two-thirds of injections being used in India are unsafe, posing health hazards such as hepatitis B, hepatitis C, and HIV. According to WHO, up to 40% of injections worldwide are given with syringes and needles reused without sterilization. Read more
WHO Urges Governments to Act on Hepatitis Threat
July 29 - WHO is urging governments to act against the five hepatitis viruses that can cause severe liver infections and leads to 1.4 million deaths every year. WHO also released its first-ever country hepatitis survey, covering 126 countries. Read more
Group Wants Law for Workers With Hepa B – Philippines
July 29 – A group of doctors called on lawmakers to pass a bill that will set clear-cut policies to protect workers who test positive with hepatitis B in the workplace in the Philippines. Read more.
Israel's SciVac Eyes Global Expansion of 3G Hepatitis B Vaccine
July 29 - Israeli drug company SciVac is seeking U.S. approval for a widely used hepatitis B vaccine as part of a push for increased global sales of a product, which it says could stem global growth in the disease. Read more
In Asia Pacific, One Death Every 30 Seconds From Viral Hepatitis
July 22 – The number of people dying from viral hepatitis has reached one million every year in the Asia Pacific Region, a death rate that is three times higher than HIV/AIDS. Read more
Many People Need Hepatitis B Treatment in Gambia
July 22 - About 8% of people tested through a community-based screening program in Gambia have hepatitis B, and about 8% of these have advanced liver disease and meet European criteria for antiviral therapy based on findings from PROLIFICA - Prevention of Liver Fibrosis and Liver Cancer in Africa, the first program aimed at testing, assessing, and treating chronic hepatitis B in West Africa. Read more.
Inequalities in the Treatment of Hepatitis Require EU Intervention
July 22 – Differences in prevention, detection and access to treatment of viral Hepatitis in different European Union member states are alarming. Read more
Hundreds Call Hepatitis Helpline
July 22 – Hundreds of people have been calling The Hepatitis Foundation of New Zealand following the launch of their “Can You Say Yes” hepatitis B campaign aimed at encouraging those at risk to be tested for hepatitis B. Read more
Cancer Among Asian Americans
July 15 – Liver cancer is a leading cause of death for Asian Americans, but few know chronic HBV is a risk factor. A new campaign, “Know Hepatitis B”, launched by the CDC and Hep B United aims to improve awareness, advocate for testing, and improve care, treatment and health outcomes by educating AAPI communities. Read more
Family Promise: Get Tested for Hepatitis B
July 15 – One in 12 Asian Americans has hepatitis B, but 2 in 3 don’t know they have it. Protect your family and get tested for hepatitis B. View the new CDC PSA.
Govt Steps Up Efforts in Fight Against Spread of Hepatitis
July 15 - Concerned about the high prevalence of hepatitis B, the Health Ministry will carry out nationwide screening tests for pregnant women this year to prevent further spread of the HBV, beginning in Jakarta. Read more
GLOMEF Intensifies Public Education on Hepatitis B
July 15 – The Global Media Foundation (GLOMEF), a human rights and anti-corruption media advocacy organization in Ghana has intensified public education on HBV, especially among the rural folk with much focus on market women and farmers. Read more
Recall of Possibly Tainted Hepatitis B Vaccine
July 8 – Pharmaceutical giant Merck & Co. voluntarily recalled a single lot of its hepatitis B vaccine due to the possibility of cracked vials, which may compromise sterility. Read more
Ancient Origin of Hepatitis B Viruses Revealed by DNA Fossils in Bird Genomes
July 8 – The hepatitis B virus originally infected birds back when the dinosaurs still roamed the planet, according to a newly published study of genomic bird DNA, a finding that may help improve human health outcomes. Read more
Intestine Bugs Could Be Key To Obesity-Cancer Link
July 8 – Researchers in Japan report that obese mice carry an altered gut flora, which is linked to an increase in the production of DNA-damaging acid that causes liver inflammation and cancer. Read more
Scientists Create ‘Human Liver’ From Stem Cells
July 8 – Scientists in Japan said they had grown human liver tissue from stem cells in a first that holds promise for alleviating the critical shortage of donor organs. Read more
New USPSTF Hepatitis C Testing Recommendation Hailed by NVHR
July 1 - U.S. Preventive Services Task Force (USPSTF) has released updated hepatitis C screening recommendations to test all people born from 1945 to 1965. Individuals born between these years have the highest rates of chronic infection and represent 75% of the more than 4 million cases of HCV in the U.S. Read more
Experts Warn of a Liver Cancer Time Bomb
July 1 - Increased diagnosis and treatment of people with hepatitis B is vital to prevent a liver cancer time bomb, experts warn. A liver cancer prevention policy launched by the Cancer Council on Monday calls for increased testing of groups at risk of hepatitis B, and notes that less than half of Australians affected are aware they carry the disease. Read more
Adherence To and Initiation of HBV Therapy Prove Problematic In Real-World Settings
July 1 - Mindie H. Nguyen, MD, of Stanford University School of Medicine presented two studies at DDW that found medical non-adherence can be a larger issue than antiviral resistance, and that many factors beyond patient noncompliance can contribute to this problem and lead to virologic breakthrough. Read more
Hepatitis B Total Rises to 18 in Investigation of North Charleston Center
July 1 – A total of 18 people have tested positive for HBV since the state health department launched an investigation into a North Charleston medical clinic since May. All the people involved received at least one injection from Tri-County Spinal Care Center, the health department said, because “several lapses in infection control procedures” were identified at the facility. Read more
Anti-HBV Vaccine Fails Against Chronic Hepatitis B
June 24 – A therapeutic vaccine candidate, aimed at breaking immune tolerance to the hepatitis B virus, failed in a recent trial, but the researchers believe the problem is that the adjuvant itself was too potent. Read more
Does HBV Suppression Prevent Liver Disease Progression?
June 24 – Chronic hepatitis B patients with cirrhosis may still experience liver disease progression even if they undergo antiviral treatment and achieve good virological response, according to a poster presented at the Digestive Disease Week 2013 meeting. Read more
More Patients Test Positive for Hepatitis in North Charleston Clinic Investigation
June 24 - Twelve patients of Tri-County Spinal Care Center have tested positive for hepatitis B, and the S.C. Department of Health and Environmental Control cannot determine when those individuals were infected. On May 17, DHEC notified the clinic of three patients who tested positive for hepatitis B after receiving invasive injections. Read more
Hep B United Partners with CDC on First-Ever Multilingual Hepatitis B Testing Campaign for AAPIs
June 17 – Hep B United joins the Centers for Disease Control and Prevention (CDC) in announcing the first-ever multilingual campaign for Asian Americans and Pacific Islanders (AAPIs), to increase testing for hepatitis B among this population across the United States. Read more
Scientists ID Gene Linked to Aggressive Liver Cancer
June 17 – Researchers have found a gene they say can help identify patients facing aggressive liver cancer, and may prove key to their future treatment. Read more
Supreme Court's Human Gene Ruling Draws Local Interest
June 17 – HBF’s Dr. Timothy block weighs in on the recent Supreme Court ruling that human genes cannot be patented, and the impact on future research. Read more
Joint Agency Letter to Health–related Schools Regarding Hepatitis B Discrimination
June 13 - A historic letter on behalf of the Department of Justice, the Department of Health and Human Services, and the Department of Education has been issued regarding the participation of students with hepatitis B in health-related schools and programs. This letter emphasizes the importance of the updated CDC Recommendations and is a reminder of the institution's nondiscrimination obligations under the Americans with Disabilities Act. Read more
Eradication of Hepatitis B: A Nationwide Community Coalition Approach to Improving Vaccination, Screening, and Linkage to Care
June 10 - Hep B United, a national campaign to support and leverage the success of community-based HBV coalitions provides a strategic response to the HHS Action Plan for the Prevention, Care and Treatment of Viral Hepatitis. Read more
Tenofovir and Entecavir Effectively Suppress Hepatitis B Virus
June 10 – The newer antivirals tenofovir and entecavir inhibit HBV replication more effectively than older agents, but good adherence is needed to maintain long-term viral suppression, according to a set of studies presented at the Digestive Disease Week meeting. Read more
160,000 Singaporeans Suffer From Hepatitis B, Chronic Hepatitis B
June 10 – Some 160,000 or 2.7% of Singapore’s population suffer from hepatitis B, where HBV is the most common cause of liver diseases and liver cancer as revealed at the Asian Pacific Association for the Study of Liver Week (APASL). Read more
Community Health Workers Help Increase Hepatitis B Screenings in the Asian American Population, Experts Say
June 3 – Great way to end Hepatitis Awareness Month with an update on community events that are getting more Asian Americans screened for hepatitis B. Read more
DHEC Digs Into 2 Years of Records in Hepatitis B Investigation
June 3 – The Department of Health and Environmental Control is now seeking to test as many as 500 people who visited a North Charleston spine clinic and received injections. Read more
Liver Cancer Rates a Wake-Up Call That It's Time to Address Liver Disease Epidemic
June 3 – New Canadian Cancer Statistics show that liver cancer is one of the fastest rising forms of cancer in Canada, and is a direct result of contributing liver diseases like hepatitis B and C and fatty liver disease not being identified and treated early enough. Read more
Cedar Rapids Man Gets Prison in False Hepatitis B Claim
June 3 – A Cedar Rapids man has been given prison time for posting false information on Facebook about a consumer product being tainted with Hepatitis B. Read more
AASLD Members at Forefront to Raise Awareness of Hepatitis B and C
May 28 – Viral hepatitis is an asymptomatic disease affecting more than 5.3 million Americans. The AASLD, NVHR, and other partners were pleased to participate with the Congressional Hepatitis Caucus to provide testing for hepatitis B and C and raise awareness at the US House of Representatives. Read more
Got a Fatty Liver? Here’s How to Beat the Flab
May 28 – Fatty liver, one of the causes of liver cancer, can be a scary diagnosis, but gastroenterologists say that with dietary changes and regular exercise, progression of liver damage can be prevented. Read more
Clinic 'Shocked' After 3 Patients Diagnosed With Hepatitis B
May 28 – A Charleston spinal care center is working with the S.C. Department of Health and Environmental Control after receiving the "shocking" news that 3 of its patients contracted hepatitis B after getting injections there. Read more
HHS Viral Hepatitis Action Plan Will Be Renewed
May 20 - The U.S. HHS National Viral Hepatitis Action Plan is celebrating its 2nd anniversary this year and Dr. Howard Koh, Assistant Secretary for Health of HSS, has announced that the partner agencies are committed and dedicated to renewing the Action Plan for another three years. The federal partners are currently working on their vision and priorities for 2014–2016. Read more
Hepatitis B Virus Linked with Non-Hodgkin’s Lymphoma
May 20 – Individuals with chronic hepatitis B virus infection may have an increased risk of developing non-Hodgkin’s lymphoma, according to findings recently published in The Lancet Oncology. Read more
NJ Recognizes May As National Hepatitis Awareness Month
May 20 – The New Jersey Department of Health, leader of an active HBV coalitions and Hep B United member, recognizes May as National Hepatitis Awareness Month. Read more
Bayer Begins Phase III Trial of Regorafenib in Patients with Hepatocellular Carcinoma
May 20 – Bayer HealthCare has started to enroll patients in an international phase III trial to evaluate the efficacy and safety of regorafenib for the treatment of patients with hepatocellular carcinoma who have progressed on sorafenib treatment. Read more
Eliminating Perinatal Transmission of Hepatitis B: More Than Just A Test
May 13 – Tackling and eliminating perinatal hepatitis B in the United States through the Viral Hepatitis Action Plan initiatives, vital partners and the implementation of provisions of the Affordable Care Act. Read more
Do Asian Patients Respond Better to Pegylated Interferon for Hepatitis B?
May 13 – Some Asian people with chronic hepatitis B treated with pegylated interferon may experience better outcomes on certain measures than Caucasians, though overall response rates are similar, according to a comparative analysis presented at the EASL International Liver Congress last month. Read more
Jennerex Granted FDA Orphan Drug Designation for Pexa-Vec in Hepatocellular Carcinoma (HCC)
May 13 – Jennerex's Pexa-Vec, an oncolytic immunotherapy designed to treat advanced HCC patients who have failed sorafenib, has received FDA orphan drug designation. Read more
Novel Tests Improve Diagnosis of Two Types of Liver Cancer
May 13 – New data from two clinical trials that were presented at the International Liver Congress 2013, demonstrated substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma using diagnostic urine tests. Read more
Health Providers With Hepatitis B Are No Threat to Patients, Covered By Disability Law
May 6 – New guidelines and the recent Department of Justice settlement are powerful tools to combat hepatitis B discrimination of medical professionals and students who are HBV carriers. Read more
May is Hepatitis Awareness Month
May 6 – May 1 marked the start of the month-long observance of Hepatitis Awareness Month. The observance is an important element of government-wide efforts to raise awareness about viral hepatitis and decrease health disparities by educating communities about the benefits of viral hepatitis prevention, testing, care, and treatment. Read more
Combo of 2 HIV Drugs Can Control Hepatitis B
May 6 – The HIV antiretrovirals Viread (tenofovir) and Emtriva (emtricitabine), which are typically combined as Truvada, can suppress the hepatitis B virus in three-quarters of those with “immune-tolerant” infection. Read more
Genetic Fossils Betray Hepatitis B's Ancient Roots
May 6 – A virus that causes liver diseases in people may have infected birds that shared the planet with dinosaurs. Read more
Five Reasons Asian Americans Should Get Tested for Hepatitis B
April 29 – More than 1 million Americans have a lifelong, or chronic, infection of hepatitis B. This includes one out of every 12 Asian Americans. If you or your parents were born in Asia or the Pacific Islands, the Centers for Disease Control and Prevention (CDC) recommends that you get tested for hepatitis B. Read more.
Health-Care Worker Visits Increase Hepatitis B Screening Rates for Hmong Americans
April 29 – Lay health workers increased screening rates for the hepatitis B virus and knowledge about the disease among a group of Asian Americans, known as the Hmong, UC Davis researchers have found in the first study of its kind. Read more.
Novel Therapeutic Approaches to Cure Chronic HBV Infection
April 29 – Exciting new data presented at the International Liver Congress 2013 include results from early in vitro and in vivo studies targeting covalently closed circular DNA (cccDNA), which may form the basis of a cure for chronic hepatitis B virus infection. Read more.
New Drug Stimulates Immune System to Kill Infected Cells in Animal Model of Hepatitis B Infection
April 29 – A novel drug, GS–9620, developed by Gilead Sciences and tested in an animal model at the Texas Biomedical Research Institute in San Antonio suppresses hepatitis B virus infection by stimulating the immune system and inducing loss of infected cells. Read more.
Dozens of Oklahoma Dentist’s Patients Positive for Hepatitis
April 22 - Dozens of patients of an Oklahoma dental clinic shuttered for unsanitary conditions have tested positive for hepatitis, according to a joint statement issued by Oklahoma State Department of Health and the Tulsa Health Department. Read more.
FDA Approves FibroScan® for Non-invasive Liver Diagnosis
April 22 - Echosens™ announces its FibroScan® device received 510(k) clearance from the U.S. Food and Drug Administration (FDA) on April 5th, 2013 and is now ready to market its pioneering technology in the United States. Read more.
Liver Disease a Major Cause of Illness and Death Across the European Union: Action Needed to Save Lives
April 22 – Liver disease is the cause of a considerable burden of illness across the European Union (EU), investigators report in The Journal of Hepatology as a result of viral hepatitis, consumption of alcohol and fatty liver disease. Read more.
Interferon Induces Persistent Viral Infection, Suggests A New Approach To Clearing Infections From AIDS To Hepatitis
April 22 – Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C. Read more.
Public Health Response to Improper Infection Control at Tulsa Dentist Office
April 15 – As of April 11, there were 2,432 people who visited the Tulsa Health Department clinic to be screened for hepatitis B, hepatitis C and HIV following the recent announcement regarding the public health response to the improper infection control practices of Tulsa oral surgeon W. Scott Harrington. Read more.
Scientists Test Smallpox Vaccine as Cancer Killer
April 15 - Scientists at the University of California San Diego are conducting a multicenter clinical trial to see if genetically engineered smallpox virus can be used to fight liver cancer. Read more.
Australian Medical Association Calls for Mandatory Proof of Vaccination
April 15 – Parents who fail to vaccinate their children should face barriers to enrolling them in school and childcare centers, the Australian Medical Association says. Read more.
Tenofovir and 3TC Prevent New Hepatitis B Infections in Gay Men Living With HIV
April 8 – The inclusion of 3TC or tenofovir in antiretroviral treatment regimens reduces the risk of infection with hepatitis B virus (HBV) for gay men living with HIV who have not been vaccinated against HBV. Read more.
Liver Diseases Pose Major Problem in Future for Health Care Professionals: Report
April 8 – British Columbia (B.C.) needs more resources dedicated to the awareness, prevention and treatment of liver disease if it is to head off a brewing public health crisis, says one of the province’s leading liver specialists. B.C. has the third-highest rate of chronic hepatitis B infection in Canada. Read more.
He Battled Liver Cancer Thrice, and Won
April 8 – An amazing 52 year-old man is the recipient of a liver transplant, and has battled liver cancer three times in ten years as a result of a hepatitis B infection passed to him at birth from his mother. Read more.
Oklahoma Dental Patients May Have Been Exposed to HIV, Hepatitis B, Hepatitis C
April 1 – Health officials are urging 7,000 patients of an Oklahoma dentist to be tested for potential exposure to HIV, hepatitis B and hepatitis C. Read more.
New NIH Award Aims to Reduce Asian American Hepatitis B Disparities Through Health Information Technology
April 1 – A new grant award by the National Institute on Minority Health and Health Disparities of the NIH will support the development of new Health Information Technology (HIT) strategies by AAPCHO to increase screening for chronic hepatitis B and reduce the impact of hepatitis B among high-risk Asian American and Pacific Islander (AAPI) populations. Read more.
Drug 'May Reverse Liver Disease'
April 1 – A cheap and readily available drug could reverse severe liver disease, even in patients who find it impossible to give up alcohol, research suggests, and may provide an alternative to a liver transplant. Read more.
Chinese Airline Sued for Hepatitis B Discrimination During Recruitment
April 1 – In what is believed to be the first court case involving hepatitis B discrimination in China’s airline industry, charter flight operator, Capitol Airlines is being sued for refusing to employ a pilot because he had HBV. Read more.
Responding to Viral Hepatitis Through Health Reform
March 25 – NASTAD releases the primer on viral hepatitis and the Affordable Care Act (ACA) in light of the ACA’s anniversary. The ACA provides an opportunity to not only improve access to essential care and treatment for people living with viral hepatitis, but to diagnose viral hepatitis earlier and prevent new infections. Read more.
Hep B Poorly Managed in Kids, Pregnant Women
March 25 – Mother-to-child hepatitis B transmission continues despite vaccination and immunoglobulin administration and there is “scope for considerable improvement”, say Victorian experts. Read more.
Hepatitis B Treatment Named as Top-Selling Drug for Last Year
March 25 – A pharmaceutical for the treatment of chronic hepatitis B was the top-selling drug in Taiwan last year, taking the top by replacing a drug tackling high blood pressure. Read more.
Soybean Meal Peptides Could Stop Colon, Liver and Lung Cancer Growth
March 25 – The bean used to make tofu could also have powerful anti-cancer properties, according to a new study published in the Journal Food Research International. Read more.
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School Cheers as Student Donates Liver to His Dad
March 18 – A Taipei high school student puts his education on hold so he can donate part of his liver to his father, a hepatitis B carrier with cirrhosis. Read more.
Arrowhead RNAi Candidate ARC-520 Induces Greater than 90% Reduction in Circulating HBV DNA in Chimpanzee with Chronic Hepatitis B
March 18 – Arrowhead Research Corporation, a targeted therapeutics company, announced that a study of its RNAi-based candidate ARC-520 in a chimpanzee chronically infected with the human hepatitis B virus supports findings from rodent models indicating that it can knock down HBV DNA and key viral antigens. Read more.
PEG-IFN May Improve Response to Entecavir for HBV
March 11 – Adding pegylated interferon alfa-2a to entecavir increases treatment response in patients with chronic hepatitis B virus infection who are HBeAg positive, according to preliminary results from an international clinical trial. Read more.
Pennsylvania Biotech Center, Created by Hepatitis B Foundation Has Huge Economic Impact
March 8, 2013 - The PA Biotechnology Center, created by the Hepatitis B Foundation, has generated $579 million for the region and state, and 573 jobs over the past 4 years, according to the Economic Impact Study 2013, released by Byler Associates. View Video.
Justice Department Settles with the University of Medicine and Dentistry of New Jersey Over Discrimination Against People with Hepatitis B
March 5 – The U.S. Justice Department has reached a settlement with the University of Medicine and Dentistry of New Jersey that resolves complaints that some applicants were unlawfully excluded because they have hepatitis B. Under the settlement, UMDNJ will adopt a disability rights policy and allow the applicants to enroll. The Hepatitis B Foundation is proud to have played a role in successfully advocating for these students. Read more.
Arrowhead Data Demonstrates RNAi Candidate ARC-520 Silences Hepatitis B Virus
March 4 – Drug developer Arrowhead Research Corp. released data demonstrating its RNAi-based candidate ARC-520 has the potential to treat chronic hepatitis B in a fundamentally different manner, with the goal of finding a functional cure. Read more.
Exposure to Hepatitis B Virus Activates Immunity in Young People, Suggesting Benefits for Earlier Treatment
March 4 – New research indicates therapeutic interventions currently withheld from younger patients with so-called ‘immune tolerance’ to hepatitis B, may in fact benefit from earlier treatment. Read more.
Tenofovir Plus Emtricitabine or Lamivudine Does Not Always Suppress Hepatitis B in HIV/HBV Coinfected
March 4 – HIV/HBV coinfected people with high hepatitis B virus levels and those who are HBeAg positive are at greater risk of not achieving HBV suppression after a year on tenofovir plus emtricitabine or lamivudine, but most did so eventually, as reported in AIDS. Read more.
Antioxidant N-acetlycystein Improves Survival of Transplanted Liver
March 4 – N-acetylcysteine (NAC) administered during recovery of a liver from a deceased donor can help reduce damage during transplantation and increase survival of the liver graft in the recipient, according to a study published in Liver Transplantation. Read more.
Considerable Proportion of HBV/HCV Cases Go Unreported
Feb 25 – Reporting of chronic hepatitis B virus and hepatitis C virus infections is improving, but is still incomplete, according to research published in the Feb. 15 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report. Read more.
Dynavax Slides as FDA Rejects Adult Hepatitis B Vaccine
Feb 25 – U.S. health regulators denied approval for Dynavax Technologies Inc's adult hepatitis B vaccine and sought additional data to evaluate its safety, delaying the market entry of a faster-acting and less frequently needed vaccine for the liver-attacking infection. Read more.
Combining Tenofovir With FTC or 3TC Boosts Chances of HBV Suppression for People Co-Infected with HIV
Feb 25 – A study involving people co-infected with HIV and hepatitis B virus shows that antiretroviral therapy that combines tenofovir with FTC or 3TC has the best chance of suppressing HBV replication to undetectable level. Read more.
Publication of First Comprehensive Literature Review on the Burden of Liver Disease in Europe
Feb 25 – The European Association for the Study of the Liver (EASL) has unveiled its new publication “The burden of liver disease in Europe” a review of available epidemiological data, which suggests the leading causes of cirrhosis and primary liver cancer. Read more.
Chronic hepatitis B: What Should Be the Goal for New Therapies?
Feb 17 – Chronic hepatitis B can be medically managed with current therapies, but not reliably “cured”. Should the goals for new therapies and potential cures be redefined? Dr. Timothy Block, HBF President and Drexel University Professor, and co-authors offer clarification in Antiviral Research. Read more.
Chronic Viral Hepatitis in Cancer Patients Requires Personalized Management
Feb 17 – The likelihood of HBV reactivation during cancer treatment has led some oncologists to advocate for more thorough and standardized HBV screening guidelines. What decisions are being made regarding a patient’s need for antiviral therapy and the duration of such therapy? Read more.
Sounding the Alarm on a Silent Epidemic: Federal HIV/STD Advisory Group Adopts Viral Hepatitis as Priority
Feb 18 – In support of enhanced cross-government efforts to address the prevention, care and treatment of viral hepatitis, a federal advisory body on HIV and STDs recently expanded its scope and title to include viral hepatitis. Read more.
U.S. Court Invalidates Patent on Bristol Hepatitis B Drug
Feb 18 – A U.S. federal court has invalidated the U.S. patent on Bristol-Myers Squibb Company’s Baraclude treatment for hepatitis B after a challenge from generic drug maker Teva Pharmaceutical Industries. Read more.
Saint Louis University Research Aims Knockout Punch at Hepatitis B
Feb 11 – Saint Louis University investigators together with collaborators from the University of Missouri and the University of Pittsburgh report a breakthrough in the pursuit of new hepatitis B drugs that could help cure the virus. Researchers were able to measure and then block a previously unstudied enzyme to stop the virus from replicating. Read more.
Modified Smallpox Vaccine Stymies Liver Cancer in Study
Feb 11 – A genetically modified smallpox vaccine shrunk tumors in liver cancer patients and extended survival more than a year, a study found. Read more.
HIV Associated With Nonresponse to HBV Vaccine
Feb 11 – The response of adults with HIV to hepatitis B virus vaccination was investigated by researchers from the University of Washington and Kenyatta National Hospital in Kenya, and may provide best practices for re-vaccination of those with HIV infection that do not respond to the HBV vaccine. Read more.
One-Third Cases of Hepatitis B, C Preventable
Feb 11 – A recent study shows about one-third of the hepatitis B and C cases in Pakistan can be prevented by interventions directed towards a few selected and modifiable risk factors. Read more.
Chronic Hepatitis Cohort Study Sheds Light on Burden of Hepatitis B and C in U.S.
Feb 4 – People born between 1945 and 1964 account for the highest proportion of hepatitis B and C cases, and these viruses are a significant cause of illness and death, according to an analysis described in Clinical Infectious Diseases. Read more.
Medgenics Launches First Clinical Trial in Hepatitis to Use INFRADURE Tissue Treatment
Feb 4 – The first phase I/II study of INFRADURE, a subcutaneous autologous skin tissue implant for continuous production and delivery of interferon to treat HBV, HCV and HDV is underway, with the aim to replace months of weekly injections of interferon and associated serious side effects. Read more.
Celsion's Experimental Liver Cancer Treatment Fails in Late-Stage Trial
Feb 4 – Celsion Corporation announced its experimental liver cancer treatment, Thermo-Dox in combination with radio frequency ablation, failed to demonstrate significant progression free survival for patients with hepatocelluar carcinoma. Read more.
Government Commissions Research on Hepatitis B In Rwanda
Feb 4 – Rwanda’s Ministry of Health is conducting research to establish the prevalence of hepatitis B in the country. Read more.
NIH Awards AAPCHO Over $700,000 to Study Impact of Health Information Technology on Asian Americans Living With Viral Hepatitis
Jan 28 – The Association of Asian Pacific Community Health Organizations (AAPCHO) received a 3-year grant totaling over $700,000 from the NIH to develop new Health Information Technology strategies that increase screening for chronic hepatitis B and reduce the impact of HBV among high-risk Asian American and Pacific Islander populations. Read more.
Hepatitis B Genotype C Linked to Increased Hepatoma Risk
Jan 28 – Of all the major hepatitis B virus genotypes, genotype C carries the highest risk for hepatocellular carcinoma, Chinese researchers say. Read more.
Heavy Alcohol Use Increases Liver Cancer Risk for People With Hepatitis B
Jan 28 – Hepatitis B patients with liver cirrhosis who consumed large amounts of alcohol were more likely to develop hepatocellular carcinoma (HCC) than people who drank less, according to a report in the December edition of Hepatology. Read more.
Co-Infection With Hepatitis B or C is a Risk Factor for Reduced Bone Mineral Density Among Women With HIV
Jan 28 – After comparing bone mineral density between people with HIV infection alone and people with chronic viral hepatitis co-infection, a study published in the Journal of Acquired Immune Deficiency Syndromes found woman coinfected with hepatitis B or C and HIV had reduced bone mineral density. Read more.
Liver Disease Is Leading Cause of Death for People with Chronic Hepatitis B
Jan 21 – Advanced liver disease caused by hepatitis B virus, – including hepatocellular carcinoma and decompensated cirrhosis – accounted for more than 40% of deaths of people with chronic HBV in a large health maintenance organization, researchers reported in Hepatology. Read more.
Health Care-Related Exposure Linked to HCV, HBV Infection in Older Adults
Jan 21 – Older patients who received healthcare had increased risk of becoming infected with hepatitis B or hepatitis C. Patients' behavioral risks — being in jail, using "non-injected illicit drugs," or having sex with hepatitis-infected partners or with multiple partners — had no relation to this increased risk. Read more.
Mercer Counters High Hep B Numbers With Free Vaccinations
Jan 21 – West Virginia has the highest rate of Hepatitis B in the U.S., with Mercer County rates higher than both the state and national rates. Read more.
Viruses Prompt Oncogenic Transformation By Genetically Altering Infected Cells As Seen In Hepatitis B
Jan 21 – MiR–148a is repressed by hepatitis B virus X protein (HBx) to promote the growth and metastasis of liver cancer, as reported in the Journal of Clinical Investigation. Read more.
NIH Scientists Shed Light on Mystery Surrounding Hepatitis B Virus
Jan 14 – Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health, and the University of Oxford, U.K., have shed light on a long-standing enigma about the structure of a protein related to the Hepatitis B virus were reported in Structure, and may lead to new therapeutic strategies for chronic liver disease. Read more.
Adolescents May Lose Hepatitis B Virus Protection Despite Vaccination as Infants
Jan 14 – New research presented in Hepatology reveals that a significant number of adolescents lose their protection from hepatitis B virus infection despite having received a complete vaccination series as infants. Read more.
716 Patients at VA May Have Been Exposed to HIV, Hepatitis
Jan 14 – More than 700 patients at the Buffalo VA Medical Center may have been exposed to HIV, hepatitis B or hepatitis C because of the inadvertent reuse of insulin pens intended to be used only once. Read more.
Hepatitis B treatment and Care in the UK Need to Evolve to Keep Pace With the Global Epidemic
Jan 14 – “Persistent HBV infection has changed its face in the UK,” research published in the online edition of Clinical Infectious Diseases shows. The study found considerable diversity in viral genotype and patient ethnicity, and that only one in three patients were taking therapy. Read more.
Most Hepatitis B Patients Who Respond to Tenofovir Show Improved Liver Health at 5 Years
Jan 7 – Treatment with tenofovir remains safe and effective over 5 years, and people who achieve sustained viral load suppression experience improvement in liver histology, including regression of fibrosis and cirrhosis, according to study findings described in The Lancet. Read more.
Treatment of HBeAg Positive Chronic Hepatitis B: Interferon or Nucleoside Analogues
Jan 7 – A review of clinical aspects of the management of chronic HBV with either interferon or nucleoside analogues are featured in Liver International, proceedings of 6th Paris Hepatitis Conference, International Conference on the Management of Patients with Viral Hepatitis. Read more.
Hepatitis B Vaccine 95% Effective in Reducing Cancer, Other Ailments
Jan 7 – A medical practitioner based in Abuja, Abiodun Ajayi, has called on Nigerians to adhere to WHO’s recommendation of Hepatitis B vaccination to prevent acute and chronic HBV and liver cancer cases. Read more.
Long Term Antiviral Hepatitis B Treatment Advocated
Dec 24 – Study results published in TheLancet support the long-term use of tenofovir for chronic hepatitis B virus, showing that it can suppress the virus and lead to regression of fibrosis and cirrhosis in patients after 5 years' treatment. Read more.
Entecavir Shows Good Efficacy for Black and Hispanic Hepatitis B Patients
Dec 24 – The nucleoside analog entecavir worked as well for previously untreated African-American and Hispanic/Latino hepatitis B patients as it did for the majority white and Asian study populations in prior clinical trials, according to a poster presented at the AASLD Meeting last month. Read more.
Doc Infects Patients With Hepatitis B During Surgery
Dec 24 - A doctor with hepatitis B who preformed joint replacement surgeries unknowingly passed the virus on to at least two of his patients, according to a new report. Read more.
Adding Pegylated Interferon to Entecavir Improves HBV Treatment Response
Dec 17 - Intensifying entecavir treatment for hepatitis B by adding pegylated interferon lowers HBV viral load and increases the likelihood of hepatitis B "e" antigen loss, according to a report at the 2012 American Association for the Study of Liver Meeting. Read more.
HBV Screening Hit or Miss in Rituximab Users
Dec 17 – At least in one academic medical center, half of cancer patients on rituximab (Rituxan) were not screened for hepatitis B virus infection as recommended. Read more.
Doctor Making a Difference in the Fight Against Hepatitis B
Dec 17 – Inspiring story of Dr. Loc T. Le who overcame tremendous odds to become a successful medical doctor and teacher. Dr. Le is a passionate HBV expert and advocate and is now the chairman of the National Task Force on Hepatitis B. Read more. Read more.
Focus on Hepatitis in Togo
Dec 17 – The spread of viral hepatitis in Togo, where there is little awareness of the disease and most people discover by chance that they are infected, is causing concern, says the Save Africa from Hepatitis Society (ASADH), which is working with the Health Ministry to combat the disease. Read more.
Adult Antiviral Drug Effective in Suppressing Hepatitis B in Teens
Dec 10 – A recent clinical trial found that the adult antiviral drug, tenofovir, is safe and effective in treating adolescents with hepatitis B virus. Trial results published in the December issue of Hepatology, show that tenofovir DF suppressed HBV in 89% of pediatric participants. Read more.
A Killer on the Rise: FGM Blamed for Hepatitis B ‘Yellow Jaundice’ Deaths in Liberia
Dec 10 – The practice of Female Genital Mutilation (FGM), practiced prior to civil war in 1989, is one of the major factors responsible for the transmission of hepatitis B in the women of Liberia. Read more.
China Labor Force Issues: Hepatitis B Virus and Infectious Diseases
Dec 10 – An interesting look at hepatitis B discrimination in the Chinese work force, where “legally speaking it is not proper to discriminate against HBV carrier applicants for employment”. Read more.
Do Not Mix Hepatitis B Drug Adefovir With Stribild HIV Combo Pill
Dec 10 – The FDA has announced an update to the label information for adefovir (Hepsera), adding the 4-in-1 antiretroviral combination pill Stribild (elvitegravir/cobicistat/tenofovir/emtricitabine) to the list of other products that should not be co-administered with adefovir. Read more.
Painkillers May Protect Liver
Dec 3 – Non-steroidal anti-inflammatory drugs (NSAIDs), especially aspirin, may help prevent liver cancer, a large observational study suggested, though there is a concern with the risk for bleeding. Read more.
Nucleoside Analogs Reduce Hepatitis B Liver Cancer Risk, Cirrhosis Remains a Concern
Dec 3 - Treatment of chronic hepatitis B with nucleoside/nucleotide analogs can reduce the risk of developing hepatocellular carcinoma, but there are caveats according to studies presented at AASLD 2012. Read more.
European Commission Approves Viread for Hepatitis B in Adolescents and for HIV-1 in Children and Adolescents
Dec 3 – Viread (tenofovir) is now approved for the treatment of chronic hepatitis B virus infection in adolescent patients aged 12 to less than 18 years with compensated liver disease and evidence of immune active disease in Europe. Read more.
Gene May Hold Key to Controlling Hepatitis, HIV and Tuberculosis
Dec 3 – The gene Arih2, fundamental to the function of the immune system, may hold the key to treating and potentially controlling chronic infections such as hepatitis B, HIV and TB, according to authors of a new study published in the journal Nature Immunology. Read more.
Tenofovir Safe for Long-term Hepatitis B Treatment with Little Bone Loss
Nov 26 - Two studies show that tenofovir continues to be safe and highly effective for treating chronic HBV through 8 years of follow-up and that there is minimal bone loss among tenofovir–treated patients using the FRAX method. Read more.
Hepatitis B Vaccination Campaign For Newborns Shows Promise
Nov 26 – A hepatitis B vaccination program in Australia for Aboriginal newborns in the country’s Northern Territory significantly reduced the infection rate of the deadly disease, according to researchers at the University of New South Wales. Read more.
Smallpox Vaccine Kills Liver Cancer
Nov 26 – A global team of scientists led by Bay Area doctors is studying an unusual new technique - involving, in part, injecting a genetically engineered smallpox vaccine directly into tumors - that they hope will prolong the lives of patients with untreatable liver cancer. Read more.
FDA Panel Backs Dynavax’s Hep B Vaccine Efficacy, But Not Safety
Nov 19 – A U.S. Food and Drug Administration panel voted unanimously to recommend the effectiveness of Dynavax Inc's hepatitis B vaccine Heplisav, but raised concerns about its safety, asking for more data from studies on a wider population. Read more.
International Liver Research Community United Behind World Gastroenterology Organisation Action
Nov 19 – The World Gastroenterology Organisation declared hepatocellular carcinoma to be the major health issue on which it will focus in 2013. HCC is the number five cause of death worldwide and the number three cause of cancer deaths worldwide. Read more.
Scientists Determine How Hepatitis B&D Enter Liver Cell
Nov 19 – Scientists have filled a major gap in our understanding of hepatitis B and D by identifying the receptor that allows HBV and HDV to enter human liver cells, which may aid in the development of new therapies and treatments. Read more.
Antiviral Therapy May Cut Recurrence of Hepatitis B-Linked Liver Cancer
Nov 19 – People with liver cancer tied to infection with the hepatitis B virus who got antiviral therapy after cancer surgery had a lower risk of tumor recurrence than those who did not get it, according to a new study. Read more.
GI-13020 TarmogenR for the Treatment of Chronic Hepatitis B Generates Antigen Specific T Cell Responses
Nov 12 – GI-13020, an investigational therapeutic vaccine for the treatment of chronic HBV demonstrated immunogenicity in two key preclinical studies. Does the opportunity exist to increase HBV surface antigen serconversion rates with the use of this vaccine? Read more.
Antiviral Therapy Safe and Effective for Hep B Patients With Advanced Cirrhosis
Nov 12 - Antiviral drugs including entecavir, lamivudine, telbivudine, and tenofovir are generally well-tolerated and effective against hepatitis B virus in people with liver cirrhosis, and may lower mortality even among patients with severe decompensated cirrhosis, according to two recently published studies. Read more.
Inovio Therapeutic Hepatitis B Vaccine Killer T Cells Demonstrate Potential to Clear HBV
Nov 12 – Invovio’s synthetic therapeutic HBV vaccine generated strong T cell responses that eliminated targeted liver cells in mice. Will this new therapeutic HBV vaccine have the potential to clear hepatitis B in the liver and prevent liver cancer in humans? Read more.
New Cohort Shows the Impact of Hepatitis B and Hepatitis C on the ‘Baby Boom’ Generation
Nov 12 - A new US study provides more evidence of the disproportionate impact of viral hepatitis infections on the 'baby boom' generation, with more than half of HBV infections among patients born between 1945 and 1964. Read more.
Registry Data Shows Hepatitis B Medications Appear Safe During Pregnancy
Nov 5 – An analysis of data from the Antiretroviral Pregnancy Registry found no evidence that pregnant women's use of drugs to treat chronic hepatitis B, including lamivudine and tenofovir, is associated with birth defects. Read more.
Human-Like Mice Livers Enhance Drug Development
Nov 5 – A new bioengineering technique that substitutes human liver cells in place of mice liver cells may allow researchers to develop more effective drugs prior to clinical trials. Read more.
Cancer Breath Test: Medicine’s Next Big Thing
Nov 5 – “Each breath you take says a lot about your health”, and may be used to diagnose and stage liver and other cancers in the future. Read more and view the video.
Hepatitis E Vaccine Debuts
Nov 5 – Batches of the world’s first vaccine against the hepatitis E virus began rolling out of a Chinese factory last week, promising to stem a disease that every year infects about 20 million people and claims 70,000 lives. Read more.
Hepatitis B Patients With HBeAg Seroconversion on Treatment May Not Have Durable Response
Oct 29 – People with chronic hepatitis B virus who achieve hepatitis B "e" antigen (HBeAg) seroconversion when treated with nucleoside/nucleotide analogs are more likely to experience HBeAg seroreversion and HBV reactivation than those with natural clearance, according to a study described in the Journal of Infectious Diseases. Read more.
Mongolia Reached Regional Goal on Hepatitis B Control
Oct 29 – Despite alarming statistics estimating hepatitis B infection of more than 77% of the population at some time in their life, Mongolia has achieved the Regional goal for hepatitis B control, verified by the WHO Regional Verification Committee. Read more.
Few HCV/HBV Infections Identified in Adults With Access to Care
Oct 29 – Despite improved access to care through health care organizations, more aggressive policies for hepatitis B and C testing are needed to identify those infected, according to recent data. Read more.
Primary Care Physicians Miss Hepatitis Vaccine Targets
Oct 29 – Primary care physicians are failing to meet guidelines for hepatitis A and hepatitis B vaccination in patients with chronic hepatitis C infection, according to US research, which suggests there are substantial gaps in knowledge about the need for vaccination. Read more.
CU-Bolder Discoveries Hold Promise for Treatment of Hepatitis B Virus
Oct 23 – After three decades of searching, a University of Colorado Boulder-led team has discovered two prime targets of the hepatitis B virus, which may lead to new drug treatments for those infected with HBV. Read more.
Common Medical Screen Predicts Liver Cancer in General Population
Oct 23 – ALT and AST enzyme levels in the blood routinely monitored by physicians are also the best predictor of liver cancer risk for the general population, a team of scientists in Taiwan and The University of Texas MD Anderson Cancer Center reported in the Journal of the National Cancer Institute. Read more.
New Hepatitis B Vaccine Induces Higher Seroprotection Rates Than Engerix-B
Oct 23 – Two doses of the investigational hepatitis B vaccine, Hepislav, administered over 4 weeks induced significantly higher rates of and earlier seroprotection than Engerix-B given as 3 doses over 24 weeks based on results of two pivotal Phase 3 trials. Read more.
Vietnam, US Cooperate in Preventing Viral Hepatitis
Oct 23 – The San Francisco-Ho Chi Minh City Sister City Committee and HCMC University of Medicine and Pharmacy signed a memorandum of understanding (MoU) on cooperation to foster activities for prevention and control of liver diseases in Vietnam, where as many as 8 million people among a population of 85 million are believed to be infected with hepatitis B and C. Read more.
Statins Could be First Preventive Treatment for Liver Cancer
Oct 15 – Statins may reduce the risk for hepatocellular carcinoma, particularly in Asian versus Western patients, shows the results of a meta-analysis. Read more.
Study Reveals Prehistoric Journey of Hepatitis B
Oct 15 – A new study has revealed how the spread of hepatitis B coincides with dates of human migration throughout history, and how it could provide a framework for studying the ongoing burden and evolution of the hepatitis B virus. Read more.
Indonesia in Bold Move to Obtain Cheap Drugs for HIV and Hepatitis B
Oct 15 – The Indonesian government has quietly made an order that overrides Big Pharma's patents on seven important drugs for HIV and hepatitis B, allowing local drug companies to make cheap and affordable versions for its citizens. Read more.
Early Results Show Promise for Stem Cells in Treating Chronic Liver Failure
Oct 15 – Stem cell transfusions may someday replace the need for transplants in patients who suffer from liver failure caused by hepatitis B, according to a new study out of Beijing. Read more.
Adefovir Resistant Hepatitis B Virus Can Remain Susceptible to Tenofovir
Oct 8 – Tenofovir continues to be effective for treating chronic hepatitis B patients who have developed resistance to the related drug adefovir according to a report in the August 14, 2012 online edition of Antiviral Therapy. Read more.
26 And Already Had Two Liver Transplants
Oct 8 – An inspiring story of a 26 year-old Hispanic man, who fought for his second liver transplant after years in-and-out of hospitals due to his hepatitis B infection contracted at birth. Read more.
Life Depends on the Liver
Oct 8 – Although it is estimated that 1 in 10 in Hong Kong carry the hepatitis B virus, and liver cancer is one of the top three killers, many fail to understand the gravity of the situation, a recent survey found. Read more.
Follow-Up Lacking for Babies After Hepatitis B Vaccination: CDC
Oct 1 – Many U.S. babies born to mothers infected with hepatitis B do not receive recommended follow-up testing after vaccination, to ensure the vaccine blocked mother-to-child transmission, a new study finds. Read more.
Positive Hepatitis B Surface Antigen Tests Due to Recent Vaccination: A Persistent Problem
Oct 1 – Vaccination for HBV can produce transiently detectable levels of HBsAg in patients, though it appears unlikely to persist beyond 14 days post-vaccination. Read more.
Tenofovir is Safe and Effective For Treating Adolescents with Hepatitis B
Oct 1 – Teenagers with chronic hepatitis B virus infection responded well to 2 years of treatment with tenofovir in the first study of the drug in this population. Read more.
Countries in Western Pacific Region to Meet Hepatitis B Control Target
Oct 1 – The World Health Organization (WHO) Regional Director for the Western Pacific Shin Young-soo said that at least 30 countries and areas in the region will likely reach the target of reducing the prevalence of hepatitis B infection to less than 2 percent among children of at least 5 years old by 2012. Read more.
The Faces of HBV in America
Sept 24 – “With the number of new [HBV] infections remaining steady despite the availability of a vaccine, and the significant rise of primary liver cancer in the USA, it is imperative that hepatitis B be prioritized as an important public health concern,” according to a published statement from the Hepatitis B Foundation. The opportunity exists to reduce the prevalence of chronic HBV in the US with more rigorous screening and vaccination, particularly in certain groups that are well defined. Read more.
First Low-Cost, Paper-Based, Point Of Care Liver Function Test
Sept 24 – A new postage stamp-sized, paper-based device could provide a simple and reliable way to monitor for liver damage at a cost of only pennies per test, say researchers at Beth Israel Deaconess Medical Center (BIDMC) and Diagnostics For All (DFA), a vital diagnostic for developing countries. Read more.
Switching to Tenofovir Suppresses Hepatitis B in HIV/HBV Co-infected People
Sept 24 – People with HIV and hepatitis B virus co-infection, who substituted tenofovir for zidovudine (Retrovir) or abacavir (Ziagen) in their antiretroviral regimen, saw a reduction in hepatitis B viral load despite HBV being resistant to lamivudine, according to a poster presented at ICAAC 2012. Read more.
Sydney’s Hep B Hotspot Reveals Cancer Secret
Sept 24 – Liver cancer is estimated to soar in the next decade, particularly in migrant populations living in Sydney. Meet Oliver, a Chinese–Australian, and a lucky liver transplant recipient and liver cancer survivor. Read more.
ICAAC 2012: Hepatitis B Vaccine Effective Long-term, but Some Lose Protection After 15 Years
Sept 17 – Nearly all children who received 3 doses of the Engerix-B hepatitis B vaccine achieved protective immunity, but about 20% fell below the protective antibody threshold by year 15 and could benefit from a booster shot, Canadian researchers reported at ICAAC 2012. Read more.
China Ready to Expand Collaboration With GAVI
Sept 17 –The expansion of China’s collaborative efforts with the GAVI Alliance by sponsoring and engaging in multilateral aid efforts in the public health sector were discussed in meetings between GAVI CEO Dr. Seth Berkley, and China’s Health Minster. China has had a successful hepatitis B vaccination campaign, and it is hoped they will be able to produce and distribute affordable, life-saving vaccine in sufficient quantities so children throughout Africa and Asia may benefit. Read more.
Report: Exercise is Good For Your Liver
Sept 17 – Regular exercise and eating a nutritious, balanced diet is extremely important to the health of your liver, and now a study indicates it is important in terms of the progression of liver cancer. Read more.
Earlier Treatment for Young Patients with Chronic Hepatitis B More Effective in Clearing Virus
Sept 10 – Contrary to current belief, children and young patients with chronic hepatitis B, do have a protective immune response and may be more suitable candidates for treatment than previously considered. Read more.
Hepatitis B Rates Higher Than Expected Among Gay Men, Drug Users, Vaccinated Babies
Sept 10 – An unexpectedly high proportion of gay/bisexual men and injection drug users develop chronic hepatitis B rather than clearing the infection, reported in the Journal of Hepatology. Other recent studies found that more than one-quarter of children born to mothers with hepatitis B showed evidence of "occult" HBV infection despite vaccination at birth, and that some individuals vaccinated as children may still show evidence of infection as adults. Read more.
Hepatitis Epidemic Must be Tackled to Stop Liver Cancer Cases Doubling
Sept 10 – Liver cancer experts at the Australasian Viral Hepatitis Conference in New Zealand are urging Australian and New Zealand governments and health professionals to set new targets for the number of people receiving treatment for hepatitis B and C, which are largely responsible for the soaring liver cancer rates in both countries. Read more.
Entecavir/Tenofovir May Benefit Chronic HBV Patients With Higher DNA Levels
Sept 10 – Therapy with entecavir and tenofovir was similarly as effective as entecavir alone in patients with chronic HBV, but improved response among hepatitis B e antigen-positive patients with higher baseline HBV DNA levels. Read more.
Hepatitis B: Deadlier Than Ever
Sept 4 – Hepatitis B is “on a silent rampage in the Philippines” where 60% of the population has been infected with HBV and 10% are chronically infected. The Hepatitis B Foundation was cited as an expert resource addressing global hepatitis B. Read more.
Tenofovir Hepatitis B Label Update Adds Info on Kids, Longer-term Data for
Sept 4 – The U.S. Food and Drug Administration announced that product label information for tenofovir (Viread) has been revised to include further information about treatment of chronic hepatitis B in teenagers and 240-week data for adult patients. Read more.
Kindergartens Refuse Hepatitis B Carriers
Sept 4 - More than 30 percent of China's kindergartens refuse to enroll children who are infected with the hepatitis B virus, according to Beijing Yirenping Center report released last week. Read more.
R. Palmer Beasley, Expert on Hepatitis B, Dies at 76
Aug 27 – Dr. R. Palmer Beasley, an epidemiologist who discovered hepatitis B is easily transmitted from infected mother to baby during childbirth, confirmed the role of HBV in causing liver cancer, and who saved millions by helping to persuade WHO to include the hepatitis B vaccine in its global recommendations for immunizations, has passed away. Read more.
Novel Treatment for Hepatitis B, HIV Raises $23M
Aug 27 – Novira Therapeutics, a biotechnology company with a novel drug treatment for hepatitis B and HIV patients, could change the way drugs combat viruses, and potentially lead to better cure rates through the development of capsid–targeting antivirals. Read more.
AIDS 2012: HIV/HBV Coinfection Linked to Higher Mortality, More ART Liver Toxicity
Aug 27 – Approximately 6% of people with HIV receiving antiretroviral treatment in Tanzania were coinfected with hepatitis B, which was associated with an elevated risk of death, smaller CD4 T–cell gains and greater likelihood of liver toxicity. Read more.
CDC Now Recommends All Baby Boomers Receive One–Time Hepatitis C Test
Aug 20 – CDC estimates one–time hepatitis C testing of baby boomers could identify more than 800,000 additional people with hepatitis C, and will avert major increases in liver related disease and deaths in the U.S. Read more.
Hepatitis B – What’s New On the HBV Vaccine Watch?
Aug 20 – Dr. Timothy Block from the Hepatitis B Foundation spoke about the prevention of Hepatitis B and the unmet needs in terms of both prevention and treatment of the disease at the World Vaccine Congress 2012. Read more.
Unsafe Injection, Bane of Health Care Systems
Aug 20 – Many of the 20 billion injections given annually, around the world, may be unnecessary and unsafe. Unsafe injection practices are a powerful engine to transmit blood–borne pathogens such as HBV, HCV and HIV, and may lead to disease, disability and death. Read more.
Ten Years of Hepatitis A Protection
Aug 20 – The hepatitis A vaccine remains effective for 10 years in children, according to a recent study conducted by the Centers for Disease Control in the Division of Viral Hepatitis, and published in Hepatology. Read more.
New Drug Successfully Halts Fibrosis in Animal Model of Liver Disease
Aug 13 – A study published in the online journal Hepatology reports a potential new NADPH oxidase (NOX) inhibitor therapy for liver fibrosis, a scarring process associated with chronic liver disease such as hepatitis B. Read more.
A New Mexico Experiment Aims to Fix the Doctor Shortage – No New Doctors Required
Aug 13 – Project ECHO is an innovative way to manage health conditions like hepatitis C in a primary care setting, thereby increase the capacity of the current health care system without adding personnel. Read more.
Yiren Ping: Strong Condemnation to the Forceful Blockage of the Most Popular Hep B Patient Rights Website in China Just Before World Hepatitis Day
Aug 13 – After technical testing, it was determined that the popular website for people living with HBV is being blocked in mainland China by the authority of Great Fire Wall in China. Read more.
Sleep and Antibody Response to Hepatitis B Vaccination
Aug. 6 – People who regularly get more than seven hours of sleep a night are more likely to respond to vaccination against hepatitis B compared to those who get in less than six hours, according to new research. Read more.
CAPAC Marks Fifth Annual World Hepatitis Day
Aug. 6 – Members of the Congressional Asian Pacific American Caucus (CAPAC) showed their support of World Hepatitis Day by encouraging communities and governments around the world to work together against the “silent killer,” and discussed disparities among the AAPI communities in the United States. Read more.
Intern With Hep B Fights Back
Aug. 6 – Despite the People's Republic of China Employment Promotion Act, which came into effect on January 1, 2012, discrimination against those infected with hepatitis B continues, resulting in loss of employment. Read more.
Lifesaving Organ Donations are a Special Need in Asian Community
Aug. 6 – Asian Americans are reminded to help others in the API community by considering the donation of lifesaving organs and tissues, since diseases like hepatitis B disproportionately affect Asians, and may result in the need for liver transplantation. Read more.
Presidential Proclamation -- World Hepatitis Day, 2012
July 30 – President Obama rededicated the commitment of his Administration to viral hepatitis by signing a Presidential Proclamation in honor of World Hepatitis Day, 2012. President Obama encouraged citizens, Government agencies, nonprofit organizations, and communities across the Nation to join in activities that will increase awareness about hepatitis and what we can do to prevent it. Read more.
Foreign Media Disclose Hepatitis Numbers On World Hepatitis Day 2012
July 30 – With the observation of World Hepatitis Day 2012 on Saturday, July 28, media outlets globally wrote about the incredibly large numbers of people infected with viral hepatitis in their own countries. Read more.
World Hepatitis Alliance Welcomes New Global Framework Aimed at Saving the Lives of Millions Living With Hepatitis
July 30 – The World Health Organization (WHO) launched its ‘Framework for Global Action’, which provides a global vision for the prevention and control of viral hepatitis and outlines four axes for action for regions and countries to develop effective strategies and plans according to their specific hepatitis burden and challenges. Read more.
Blocking of Hepatitis B Website Raises Ire
July 30 – As hepatitis carriers were celebrating World Hepatitis Day, seeking to raise awareness about the disease, one of their main sources of support went down. Ahead of the day, a well-known public welfare website dedicated to preserving the rights and interests of hepatitis B carriers was blocked in China. Read more.
CDC, Division of Viral Hepatitis (DVH), and the Hepatitis B Foundation Raise Global Hepatitis B Awareness With a Twitter Chat
July 23 – The CDC, DVH, and HBF will be hosting a World Hepatitis Day twitter chat on Friday, July 27th at 2pm EDT. Special guest, Dr. Thomas London, will be interviewed by CDC’s Amanda Lewis regarding important hepatitis B topics. Join the conversation by using the twitter hashtag #WHDchat.
Assistant Secretary for Health Howard Koh Shares Hepatitis B Awareness Tools for AAPI Communities
July 23 – As we approach World Hepatitis Day on July 28th, we are reminded of the staggering impact of hepatitis B in the Asian American and Pacific Islander (AAPI) communities. Read more.
EASL publishes revised clinical practice guidelines for chronic hepatitis B
July 23 – The European Association for the Study of the Liver (EASL) recently revised its clinical practice guidelines for the management of patients with chronic hepatitis B virus infection. The revised recommendations reflect new data, though areas of uncertainty still exist. Read more.
Liver Cancer Cases on Increase
July 23 – Ten percent of Ugandans are said to be living with chronic hepatitis B, with as many as 25% of Northern Ugandan and 7% of Southwestern Ugandan populations infected, cited by WHO Country Advisor Expanded Program on Immunization (EPI) surveillance. Read more.
State Health Officials Warn Dentist Reused Syringes, Needles
July 16 – Patients who went to a Colorado oral surgeon over the past decade are advised to get tested for HIV, hepatitis B and hepatitis C, says the Colorado Department of Public Health and Environment. Dr. Stephen Stein re-used needles and syringes on multiple patients while injecting intravenous medications. Read more.
Substantial Pathological Differences Between HCC Patients with HBV, HCV
July 16 – Patients with hepatocellular carcinoma associated with hepatitis B may be more prone to early onset of cancer and poor prognosis than patients with carcinomas associated with hepatitis C, according to recent results that also indicated several other clinical-pathologic differences between the two. Read more.
Smoking Results In Lower Immune System Responses After Transplants
July 16 – Liver transplant recipients who continue to smoke or have smoked in the past are more likely to acquire viral hepatitis reinfection after the procedure, according to a study published in Liver Transplantation. Read more.
Shortage of Liver Donors in Taiwan Puts Focus on Prevention: Doctor
July 16 – Taiwan's liver donor shortage has heightened the importance of measures to prevent liver disease, such as screening and treatment for viral hepatitis. Read more.
Hep B Screening Urged Before TNF-Alpha Inhibitor Therapy
July 9 – All patients with psoriasis should be screened for hepatitis B prior to the initiation of tumor necrosis factor–alpha inhibitor therapy, according to research published in the Journal of the American Academy of Dermatology. Read more.
Bulgaria Launches Development of National Hepatitis Plan
July 9 – The Bulgarian Health Minister together with the European Liver Patient Association (ELPA) will initiate the development of a National Hepatitis Plan in the context of a roundtable discussion with international experts on viral hepatitis in the Bulgarian Parliament. Read more.
BioDiem Licenses Australian Hepatitis B Vaccine
July 9 – Pharmaceutical company BioDiem recently acquired a license to utilize vaccine technology for hepatitis B and D from an Australian university. Read more.
Girls as Young as 12 in Hepatitis B Scare After Being Used as Guinea Pigs by Unqualified Tattoo Artist
July 9 – A cowboy tattoo artist left kids as young as 12 facing an agonizing wait to see if they are clear of hepatitis B. HBV may be transmitted through the use of unsterilized tattoo needles and equipment. Read more .
CDC Updates Recommendations for HBV-Infected Health Care Providers and Students
July 6 – CDC released its updated HBV recommendations in today's MMWR issue to clearly state hepatitis B by itself should not prevent a person from pursuing a career in health care. With increasing reports of providers and students facing HBV-related discrimination, the CDC has taken a strong position against this by including a statement that the "CDC discourages constraints that restrict chronically infected HBV health care providers and students from the practice or study of medicine, dentistry or surgery." Read more.
State-Specific Information about ACA Implementation
July 2 – On the heels of the Affordable Care Act (ACA) ruling, the US Dept. of Health and Human Services website has updated information on implementation of the ACA, including state-specific pages on the benefits thus far. Read more.
FDA Will Review New Dynavax HBV Vaccine
July 2 – The U.S. Food and Drug Administration (FDA) has indicated that it will review for approval a new hepatitis B vaccine for adults known as Heplisav that has demonstrated higher and earlier protection with fewer doses than currently licensed vaccines. Read more.
Filipino–Americans Urged to ‘B-Free’
July 2 – A Las Vegas pilot program urges Filipino–Americans to be screened for HBV since as many as 10% of this population may be positive for hepatitis B. Read more.
Management of Hepatitis B in Ghana
July 2 – There are many challenges for those living with hepatitis B in Ghana, as shared by Theobald Owusu–Ansah of the Theobald Hepatitis B Foundation and member of the World Hepatitis Alliance. Read more.
Hepatitis B Vaccine Protects for 25 Years: Study
June 25 – Vaccination against hepatitis B seems to protect against the virus for 25 years, suggesting that booster shots are unnecessary, according to a study from Taiwan. Read more.
Cuba Says Hepatitis B Eliminated Among Minors
June 25 – Cuba has eliminated hepatitis B among the population under age 15, thanks to a locally developed vaccine and the Caribbean country’s massive immunization campaign. Read more.
HBV Genotype Affects Hepatitis B Disease Progression and Outcomes
June 25 – Hepatitis B virus genotype influences long-term outcomes including viral clearance, according to a Swedish study reported in the May edition of the Journal of Clinical Virology. Read more.
Hepatitis B and Liver Cancer Among Asian Americans
June 25 – Liver cancer is expected to become more common among the Asian American and Pacific Islanders (AAPI) population. “It’s deadly and it’s preventable,” says USCF physician and researcher, Tung Nguyen, MD, as he discusses his strategy for lowering liver cancer rates among AAPIs. Read more.
Hepatocyte Cell Transplantation Enables 'New' Liver Generation
June 18 – Researchers in Japan have found that hepatocytes can be propagated and used to regenerate liver tissue as published in a recent issue of Cell Transplantation. This ability has potential clinical value for hepatocyte transplantation or other therapies. Read more.
Scientists Show Lack of Single Protein Results in Persistent Viral Infection
June 18 – A single protein can make the difference between an infection like HBV, HCV or HIV clearing out of the body or persisting for life says the Scripps Research Institute. Read more.
Strides Made In Shielding Toddlers from Hepatitis B
June 18 – China has achieved the Asia-Pacific regional goal of reducing chronic hepatitis B infection rates to less than 1% among children up to age 5, the World Health Organization said, calling it a remarkable public health accomplishment. Read more.
Most Hepatitis B Carriers Aren’t Being Treated, Survey Finds
June 11 – Most Asian-Canadians who know they are chronically infected with hepatitis B are not being treated by a doctor, says a survey released by the Chinese advocacy group S.U.C.C.E.S.S. Read more.
HIV and HBV: Partners in Crime
June 11 – HIV and hepatitis B constitute global health threat says New England Journal of Medicine. If you have HIV, one of the most dangerous risks is becoming infected with another chronic disease such as HBV. Read more.
The Risk of Perinatal Hepatitis B Virus Transmission: Hepatitis B e Antigen (HBeAg) Prevalence Estimates For All World Regions
June 11 – HBeAg presence in childbearing-age women is a major determinant of perinatal hepatitis B transmission. This assessment looks at the perinatal transmission risk of HBV by estimation of age and region-specific HBeAg prevalence. Read more.
HBV and HCV-Associated Liver Cancer: Important Insights from the Genome
June 11 – This interesting blog discusses the integration of hepatitis B in liver cancer genomes, and genes that might provide clues to the molecular mechanism of virus-associated HCC. The review was based on two Nature Genetics (May 2012) journal articles. Read more.
Prevalence of Chronic Hepatitis B May Exceed 2 Million, Higher in US Than Previously Reported
June 4 – The prevalence of chronic hepatitis B virus infection in the U.S. may be as high as 2.2 million cases according to a new study now available in Hepatology. Findings suggest the higher prevalence of chronic HBV can be attributed to foreign–born persons who were infected in their country of origin prior to arrival in the U.S. Read more.
Addressing Viral Hepatitis Among Minority Communities
June 4 – The U.S. Office of Minority Health is taking an active role in advancing the HHS Action Plan on Viral Hepatitis and promoted on its blog their partnership with the Association of Asian Pacific Community Health Organizations and the Hepatitis B Foundation to launch Hep B United. This is a new national campaign dedicated to ending hepatitis B by supporting community-based groups in their efforts to increase awareness, screening, particularly among high-risk Asian American populations. Read more.
New Data Published From Genomics Research On Recurrent Hepatitis B Virus Integration
Jun 4 – Results from a genome–wide study of recurrent hepatitis B virus integration in hepatocellular carcinoma (HCC) were published in Nature Genetics, and may have important insights that may be used to improve diagnosis and treatment. Read more.
16th Century Korean Mummy Provides Clues to Hepatitis B Virus Genetic Code
June 4 – A liver biopsy and genetic analysis on a mummified Korean child has revealed a unique hepatitis B virus genotype C2 sequence. Study of HBV genomes may be used as a model to study the evolution of chronic HBV and help understand the spread of the virus. Read more.
CDC Initiative Aims to Improve HBV Screening Among Foreign-born U.S. Residents
May 29 – The Centers for Disease Control and Prevention (CDC) has launched a demonstration project to find, screen and treat immigrants and refugees living in the United States who come from countries where hepatitis B is endemic. The goal is to slow the spread of HBV among foreign-born residents of the U.S. who now account for the majority of chronic HBV in the country. Read more.
Sanofi to Test Cancer-Starving Compound in China in 2013
May 29 – Sanofi–Aventis plans to begin testing a novel compound that is designed to starve liver cancer to death in a phase one human clinical trial in China and possibly South Korea in 2013. Read more.
Hepatitis B Carriers May Now Work in Nurseries
May 29 – Carriers of the hepatitis B virus are now allowed to work at kindergartens and nurseries on the Chinese mainland, under new guidelines on health and hygiene at kindergartens, hopefully resulting in reduced HBV related social discrimination. Read more.
Campaign Calls for Increased Hep B Testing in Philly
May 21 – Philadelphia Mayor Nutter and Councilman David Oh were featured speakers at a media event organized by Hep B United Philadelphia, a campaign led by the Hepatitis B Foundation to get more Philadelphians tested and vaccinated against the virus. Read more.
MMWR: Multiple Outbreaks of Hepatitis B Virus Infection Related to Assisted Monitoring of Blood Glucose Among Residents of Assisted Living Facilities – Virginia, 2009-2011
May 21 – Virginia health officials said hepatitis B virus infections occurred in four assisted living facilities from 2009-2011 due to inadequate infection control practices, particularly surrounding assisted monitoring of patient blood glucose levels. Read more.
One in 10 Cambodians Have Hepatitis B
May 21 – Cambodian Americans are 25 times more likely to have a chronic hepatitis B infection than the average American, and HBV is the second leading cause of cancer for Cambodian American men. This is due to a lack of health education and translated information about HBV for Cambodians in the U.S. Read more.
Perinatal Hepatitis B: What Every Mom Should Know
May 14 – A highlight of perinatal hepatitis B transmission and the actions needed to eliminate this preventable disease, by Corinna Dan, RN, MPH, Viral Hepatitis Policy Advisor, HHS. Read more.
1 in 6 Cancers Worldwide Caused by Infections That Can be Prevented or Treated
May 14 – Infections cause about 2 million cancer cases a year, and 80 percent of those cases occur in less developed areas of the world, many of which are due to potentially preventable or treatable infections, including hepatitis B, according a the study which was published in The Lancet Oncology. Read more.
Arrowhead Presents Data on DPC System and Hepatitis B Program at CLINAM 2012
May 14 – Arrowhead’s pre-clinical strategy for the development of an effective siRNA–based therapeutic for the treatment of chronic HBV infection was presented at the European Foundation for Clinical Medicine Conference. Read more.
Intensive Follow–up Reduces Mortality from Hepatocellular Cancer
May 14 – Intensive follow–up of patients who have undergone surgery for hepatocellular carcinoma reduces deaths from tumor recurrence and metastases, since HCC tends to recur locally, Dr. Timothy M. Pawlik said at a symposium sponsored by the Society of Surgical Oncology. Read more.
Scarring Cells Revert to Inactive State as Liver Heals
May 14 – Myofibroblasts, or cells that produce the fibrous scarring in chronic liver injury, revert to an inactive type as the liver heals. This discovery may ultimately lead to new therapies for reversing fibrosis in the liver and other organs. Read more.
CDC Selects Hepatitis B Foundation as Featured Partner for Month of May
May 10 – The CDC National Prevention Information Network (NPIN) Featured Partner resource offers HIV/AIDS, viral hepatitis, STD, and TB prevention–focused organizations a platform to showcase their services, programs, and materials. Our goal is to highlight the work of CDC’s prevention partners and encourage partners to connect with each other to share information and strategies. The Hepatitis B Foundation was selected for May Hepatitis Awareness Month for the valuable work they are doing to promote hepatitis B prevention through improved screening, vaccination and linkage to care. Read more.
Raising Awareness of Hepatitis B in the Asian and Pacific Islander Communities
May 7 – Dr. Howard Koh, Assistant Secretary for Health at the U.S. Department of Health and Human Services, wrote a blog to highlight the dual observance of both Asian and Pacific Islander Heritage Month and Hepatitis Awareness as an important opportunity to bring attention to the disproportionate burden of viral hepatitis among the Asian American and Pacific Islander communities in the U.S. and renew the federal commitment and call to action to address this disparity. Read more.
EASL: Having Only Wild-Type Hepatitis B Virus Predicts Response to Interferon
May 7 – Chronic hepatitis B patients who do not have two common HBV mutations are more likely to achieve an undetectable viral load and HBsAg loss when treated with pegylated interferon, according to a study presented at EASL 2012. Read more.
Combination of Two Drugs Reverses Liver Tumors, Study Suggests
May 7 – Primary liver cancer is the 5th most common cancer and the 3rd most deadly cancer. The combination of two inhibitors of protein mTOR stops the growth of primary liver cancer and destroys tumor cells, according to a study by researchers of the Group of Metabolism and Cancer at Bellvitge Biomedical Research Institute. Read more.
Abatacept May Aid RA Patients with Hepatitis B
May 7 – Abatacept may be helpful for treating rheumatoid arthritis (RA) in patients with concurrent hepatitis B, as long as patients are also given antiviral prophylaxis to prevent reactivation of their HBV, according to small retrospective study presented at the rheumatology meeting sponsored by New York University. Read more.
Chronic Hepatitis B Infection Associated with Twice the Risk of liver-Related Death Compared to hepatitis C
April 30 – The risk of death due to liver disease is twice as high for patients with chronic hepatitis B infection compared to individuals with chronic hepatitis C, U.S. researchers report in the online edition of Clinical Infectious Diseases. Read more.
Family History of Liver Cancer Increases Risk of Developing the Disease
April 30 – A family history of liver cancer is reported to increase risk of developing hepatocellular carcinomas (HCC), independent of hepatitis according to findings published in the May issue of Hepatology. The study also shows 70–fold elevated risk of HCC in those with liver cancer in the family and markers for HBV or HCV. Read more.
Microbiologist Irving Millman 88 Helped Develop Hepatitis B Vaccine
April 30 – Irving Millman, a microbiologist who played an instrumental role in developing the hepatitis B vaccine on the research team of Baruch Blumberg, MD, PhD, Nobel Laureate, has died. Read more.
Doctor Raises Awareness of Hepatitis B
April 30 – Raising Hepatitis B awareness and encouraging screening among the Vietnamese community of the New Orleans Metro area is a priority for Son Nguyen, MD, a gastroenterology fellow at Tulane University. Read more.
EASL: Entecavir Plus Tenofovir for Hepatitis B Patients with Prior Treatment Failure
April 23 – A combination of entecavir plus tenofovir resulted in hepatitis B virus suppression in a majority of patients who previously experienced treatment failure, according to a study presented at the 47th Annual Meeting of the European Association for the Study of the Liver. Read more.
EASL: Childhood Obesity Linked to Increased Risk of Hepatocellular Carcinoma in Adulthood
April 23 – Data presented at EASL shows that childhood obesity is positively linked with developing hepatocellular carcinoma (HCC) even when patients with other co-morbidities are removed such as those with hepatitis B or C. Read more.
Prospective Validation of FibroTest in Comparison with Liver Stiffness for Predicting Liver Fibrosis in Asian Subjects with Chronic Hepatitis B
April 23 – This prospective study examined the diagnostic performance of FibroTest and Liver Stiffness for the prediction of histological fibrosis in Asian patients infected with chronic hepatitis B. These less invasive options may provide a good alternative to the liver biopsy, often considered the gold standard for assessing liver fibrosis. Read more.
Liver Cancer Predictors in Chronic Hepatitis B Identified
April 16 – In patients with chronic hepatitis B who are negative for hepatitis B e antigen and have low viral loads, serum levels of hepatitis B surface antigen can be used to predict risk for hepatocellular carcinoma (HCC), Dr. Tai–Chung Tseng and colleagues reported in the May issue of Gastroenterology. Read more.
B.C. to Educate Asian Immigrants About Dangers of Hep B
April 16 – The Chinese immigrant support group S.U.C.C.E.S.S. along with specialists from the University of British Columbia are launching a project to educate Asian immigrants about the danger of undiagnosed hepatitis B, and to improve treatment to prevent the emotional and financial cost of drastic treatments to the patient and the health–care system. Read more.
Telbivudine Cut Mother-to-Infant Hepatitis B Transmission
April 16 – Telbivudine taken during the second or third trimester of pregnancy reduced the mother–to–infant transmission of hepatitis B to zero in an open-label trial of 88 women who had high viral loads and elevated alanine aminotransferase levels, Dr. Calvin Q. Pan and his colleagues reported in the May issue of Clinical Gastroenterology and Hepatology. Read more.
Experts’ Picks: Best of The Liver Meeting 2011—Part 2
April 16 – Gastroenterology & Endoscopy News asked the experts: What were your favorite abstracts presented at The Liver Meeting 2011? This collection of selected abstracts and comments include the influence of age, gender and race on normal ALT values for those in the US free of liver disease, along with lamivudine use in the 2nd or 3rd trimester of pregnancy among highly infectious mothers in order to prevent vertical transmission of HBV, and other favorites. Read more.
Turning Lymph Nodes into Liver-Growing Factories
April 16 – A surprising new technique is currently under development by University of Pittsburgh stem cell researcher Eric Lagasse, which uses any of the body’s 500 lymph nodes to generate a new liver. The technique is in initial stages, but might one day help those with advanced liver disease. Read more.
Chronic Hepatitis B in Pregnancy
April 9 – New consensus recommendations for the evaluation and management of pregnant women with hepatitis B, resulting from a Hepatitis B Foundation workshop, is a featured article in The Female Patient. Read more.
Why are Some Immunized Children Still At Risk for HBV Infection?
April 9 – Despite immunization, children born to mothers with replicating HBV (marked by hepatitis B e Antigen, or HBeAg), are still at risk for infection, according to the April issue of Gastroenterology. New strategies to reduce the rate of breakthrough infection must be investigated. Read more.
New Biomarker to Identify Hepatitis B-Infected Patients at Risk for Liver Cancer April 9 – Hepatitis B–infected patients with significantly longer telomeres – caps on the ends of the chromosomes that protect our genetic data – were found to have an increased risk of getting liver cancer compared to those with shorter ones, according to findings presented by researchers at Jefferson’s Kimmel Cancer Center at the American Association for Cancer Research Annual Meeting 2012. Read more.
Morriston Hospital Hepatitis B Death: Lessons Learned, Says ABM Health Board
April 9 – A cardiac patient who died after contracting hepatitis B at a Swansea hospital did not receive a high standard of care, say health chiefs. An independent external review panel was asked to investigate and a likely cause of the infection has been identified. Read more.
Increasing Routine Viral Hepatitis Testing
April 2 – Successful approaches to improving the frequency, availability and acceptability of viral hepatitis testing were explored at a day-long consultation at the Office of HIV/AIDS and Infectious Disease Policy, U.S. Department of Health and Human Services. Read more.
Hepatitis B Program Helps Cut Infant Infection
April 2 – A program to prevent chronic hepatitis B infection in newborns seems to be working, according to a new study from researchers at the Centers for Disease Control and Prevention. Read more.
Children Most Vulnerable to Breakthrough Hepatitis B Identified
April 2 – Pregnant women who carry the hepatitis B e antigen are at the greatest risk of transmitting hepatitis B virus infection to their children despite HBV immunization. It is suggested that novel preventive methods be targeted to these patients. Read more.
Hepatitis B Treatment
March 26 – A new publication incorporates current recommendations for hepatitis B treatment strategies that include AASLD, APASL, EASL, Belgian, Dutch, German, and Italian guidelines in Hepatology: A Clinical Textbook. Read more.
Twin Cities Somalis to Learn About Their Increased Risk for Liver Cancer
March 26 – In an attempt to raise awareness, a campaign is underway to inform the Somali community about their increased risk for liver cancer due to hepatitis B and C infection. Read more.
Marker of Active Hep B Infection Declines in Those Coinfected With HIV, Treated With Tenofovir
March 26 – According to a Dutch report presented at the 19th Conference on Retroviruses and Opportunistic Infections, prolonged therapy with antiviral regimens containing tenofovir is associated with a decline in hepatitis B surface antigen levels in people coinfected with HIV and hepatitis B. Read more.
Liver Cancer Patients Less Likely to Die On Wait List Than Candidates Without Carcinomas
March 26 – New research shows increasing disparity in mortality among candidates with and without hepatocellular carcinoma (HCC) who are on the waiting list for liver transplantation. Read more.
HHS Weighs Accepting Men Who Have Sex With Men as Blood Donors
March 19 – Due to the increased effectiveness of donor testing for HIV, HBV and other infectious agents, the Health and Human Services Department (HHS) is seeking comments on designing a pilot program to create “alternative donor deferral criteria” for gay men. Read more.
CEVHAP Hosts Agenda-Setting Meeting on Hepatitis Policy
March 19 – The Coalition to Eradicate Viral Hepatitis in Asia Pacific (CEVHAP) met to discuss goals focusing on improving public health policies to reduce the health, social and economic burden of viral hepatitis in the Asia–Pacific region. Read more.
Hepatitis Alarm Jinnah Lab Quick to Process ‘Blue Blood’
March 19 – More than 1,000 blood samples for diagnosing hepatitis B and C patients have not been processed at the main laboratory of Jinnah Hospital for the last month. The reason may be due to equipment shortages, or as a result of a discriminatory policy for paying versus non-paying patients. Read more.
Nigeria: Nursing Mothers Complain Over Absence of Hepatitis B Vaccine
March 19 – Nursing mothers attempting to have their children immunized against hepatitis B find that the vaccine is unavailable at public hospitals. Read more.
4 Million NK Children Vaccinated Against Hepatitis B: Agency
March 19 – 3.7 million North Korean children aged 7 to 17 have been vaccinated against hepatitis B as part of a preventive strategy to reduce future medical costs. Read more.
Arrowhead Releases White Paper on Hepatitis B Virus and Potential RNAi Treatment
March 12 – Arrowhead Research Corporation released a white paper describing the health problems and unmet needs of those chronically infected with hepatitis B, and how their Dynamic Polyconjugate enabled RNAi therapeutic in development could potentially address current HBV treatment deficiencies. Read more.
Study Shows Nurses are Exposed to Risks From Blood Exposure During Insertion and Removal of Peripheral IV Catheter
March 12 – About one in two nurses experience blood exposure, increasing the risk of infection from pathogens such as HBV, HIV, HCV and MRSA, on their skin, or in their eyes, nose or mouth at least once per month when inserting peripheral intravenous (IV) catheters. Read more.
300 Pledge to Eradicate Hepatitis B
March 12 – Leading international and national hepatologists and other medical professionals joined together to sign an appeal to the government of India to help eradicate hepatitis B. Read more.
Complete Genomics Co-Authors Paper Demonstrating Impact of Hepatitis B Virus on Liver Cancer Genomes
Feb. 27 – Genome Research has published a paper, co-authored with Complete Genomics, which describes the effects of hepatitis B virus integration into the genomes of liver cancer patients. Read more.
Three Drugs Best to Treat Hepatitis B, Doctor Says
Feb. 27 – A doctor recommends the top three drugs for HBV, with one being the most suitable for Cambodians. Read more.
Doc: All Should Be Screened For Hepatitis B, C
Feb. 27 – Most people are never routinely screened for hepatitis B and C. Education of doctors and insurance companies is needed along with the inclusion of ICD codes. Read more.
Androgen Boosts Hepatitis B Virus Replication
Feb. 20 – According to research published in the Journal of Virology, the naturally occurring steroid hormone “androgen” enables replication of the HBV virus, making males more vulnerable to the virus than females, which supports studies that show men are 3-7x more likely to develop chronic HBV infections than women and more likely to develop liver cancer. Read more.
Gov’t on “Code Yellow” vs Hepatitis B
Feb. 20 – The Philippine government has launched a “Code Yellow” program to raise awareness about hepatitis B because 60% of the population has been infected with HBV, and approximately 10% are chronically infected. Read more.
Drive to Vaccinate 570,000 Schoolchildren Against Hepatitis Begins Today
Feb. 20 – A 10–day campaign to vaccinate 570,000 students against hepatitis B begins today in Karachi. Read more.
Stress Protein Effectively Activates Replication of HBV in Liver Cells
Feb. 20 – Research shows drugs that activate the stress protein p38 may cause reactivation of an HBV infection putting transplant recipients, and possibly cancer patients, at greater risk. Read more.
Accelerated Decrease in HBsAg Seen Before HBV Clearance
Feb. 13 – Serum hepatitis B surface antigen (HBsAg) seroclearance is preceded by significant, accelerated decreases in HBsAg levels during the 3 years leading up to the loss of HBsAg. Therefore, researchers recommended HBsAg quantified testing every 2 years. Read more.
Making History: Eliminating Viral Hepatitis Disparities in the African American Community
Feb. 13 – February is African American History Month and significant hepatitis–related health disparities exist in this community. New hepatitis B infection rates remain the highest among African Americans and HBV vaccination rates are lowest among African American children. Read more.
How Reliable is Hepatitis B Vaccination in People [With] Celiac Disease?
Feb. 13 – Some studies suggest that people with celiac disease may have high levels of resistance to the HBV vaccine when compared to the general public, and that a different immunization schedule should be developed for them. Read more.
White House Pledges Support to End Viral Hepatitis
Feb. 6 – President Barak Obama met with Chris Lu, White House Cabinet Secretary and co-chair of the White House Initiative on Asian Americans and Pacific Islanders, who says that viral hepatitis is a national concern and on the White House’s radar. Read more.
Program For Hepatitis B Patients in Tangerang
Feb. 6 – Indonesia has the 3rd highest number of hepatitis B sufferers in the world after China and India so the Tangerang administration is going to offer free treatment through local community health centers for patients. Read more.
Health Officials to Launch Campaign Against Deadly Disease
Feb. 6 – The State Health Department of Mississippi is getting ready to launch its first hepatitis B public awareness campaign, focusing primarily on the large Vietnamese community in South Mississippi. Read more.
U.S. Vaccination Coverage Remained Low in 2010
Feb. 6 – Adult vaccination rates are far below the recommendations of Healthy People2020, including that of the hepatitis B vaccine which stands at only 42% of high risk adults aged 19-49. Read more.
Statins May Stave Off Liver Cancer in People With Hepatitis B
Jan. 30 – A new study in the Journal of Clinical Oncology shows that popular cholesterol lowering statins may also lower the risk for liver cancer in people with HBV, although regular liver function tests are required to prevent a potentially dangerous rise in liver enzymes. Read more.
Test For Liver Damage Uses Blood Sample Instead of Biopsy
Jan. 30 – The Enhanced Liver Fibrosis test, developed by Siemens, is used to diagnose liver damage with a blood test rather than a biopsy and in less time. Read more.
Infection Control Training Mandated at Assisted Living Centers
Jan. 30 – State mandated training is underway in an effort to deal with an increasing number of hepatitis B outbreaks caused by faulty diabetes care in assisted living centers. Read more.
Booster Vaccination Recommended For HBV Immunity in Children With IBD
Jan. 30 – Due to the risk of HBV infection in children with inflammatory bowel disease (IBD), patients should be screened for HBV at the time of IBD diagnosis, and an HBV booster dose considered in patients without protective antibodies. Read more.
Many High-Risk Americans Don’t Get Hepatitis B Vaccine
Jan. 23 – A recent study indicates more than 50% of adults at risk for HBV remain unvaccinated despite making contact with the healthcare system, resulting in missed opportunities to vaccinate this population. Read more.
GAO Asked to Review VA Quality-of-Care Policies
Jan. 23 – Top Democrats on the House and Senate Veterans’ Affairs committees asked the Government Accountability Office to investigate the VA’s handling of incidents involving improper sterilization of reusable medical equipment that have potentially exposed more than 13,000 veterans to infectious diseases such as HBV, HCV and HIV. Read more.
Guidelines for the Detection of a Common Source of Hepatitis B Virus
Jan. 23 – Belgian researchers shed light on the relationship between prevalence rates of chronic HBV in different geographic regions with transmission patterns. Additional analyses of HBV–infected populations over a period of time can help corroborate the existence of a common source of infection, which is particularly useful when investigating outbreaks. Read more.
Beware of Hepatitis B at the Nail Salon
Jan. 23 – Nancye Swanson does her own nails these days. Six months ago, she almost died from hepatitis B, a serious liver infection, which doctors say she picked up at a nail salon. Dr. Robert Gish is interviewed and the Hepatitis B Foundation is referenced in the accompanying TV news report. Read more.
Old Antivirals Rival New for Cancer Prevention in Hepatitis B
Jan. 16 – Older antiviral agents such as lamivudine or adefovir are similarly effective at preventing HCC in patients with chronic HBV versus entecavir and tenofovir despite their low rate of drug resistance. Read more.
Apple Reveals Who Makes Its iPhones, iPads, and More
Jan. 16 – Apple audits of gadget suppliers, especially those in China, found labor, health, and health and environmental violations including testing job candidates for hepatitis B. Read more.
China Approves Hepatitis E Vaccine
Jan. 16 – China has approved a hepatitis E vaccine. Hepatitis E is shed in feces and spread via tainted water and food that can lead to serious illness and death in 3% in the general population and 25% of pregnant women. Read more.
Health Dept.: Beware of Unlicensed Home Tattooing
Jan. 16 – Licensed and regulated tattoo facilities with a clean inspection history should be safe. Home tattooing and tattoo parties pose a risk of lifelong disease such as hepatitis B. Read more.
Nail Salon Nightmare: Hepatitis B From Mani-Pedis
Jan. 9 – Robert Gish, M.D., at UC San Diego, is writing a health policy for the Vietnamese government in order to prevent the spread of hepatitis B due to the high prevalence in the Asian Pacific region and those working in salons across the U.S. Read more.
Hep B Carrier Seeks Kisses For Roses
Jan. 9 – A young Chinese activist with hepatitis B exchanges kisses for roses in an effort to raise HBV awareness and decrease discrimination against those living with HBV in China. Read more.
Researchers Identify Liver Cancer Risk Factors
Jan. 9 – Two new studies from the Mayo Clinic illuminate the importance of identifying people with risk factors in certain populations to help detect disease in its early, treatable stages including HCV, HBV, and obesity, particularly fatty liver disease. Read more.
Mothers With Hepatitis B Can Breastfeed Newborns As Long As . . .
Jan. 3 – A new study suggests that mothers with HBV can breastfeed their newborn babies without the fear of transmission as long as the newborns receive HBIG and the first dose of the HBV vaccine immediately after birth. Read more.
Free Crack Pipes Handed Out to Vancouver Drug Addicts
Jan. 3 – Free crack pipes are being distributed to Vancouver addicts in an effort to stop the spread of HIV and hepatitis B. Read more.
St. Petersburg Woman Solves Mystery of Dad's 1958 Death
Jan. 3 – A woman in Florida discovers her father died in the service of his country due to a 1942 yellow fever vaccine contaminated with HBV infected blood. Read more.
Top News Stories of 2011
AASLD: Natural History of Hepatitis B Infection and Role of HBV Genotype
Dec. 23 – People with HBeAg-positive and negative HBV disease have different levels of hepatitis B surface antigen (HBsAg), variable extent of liver fibrosis, and different distribution of HBV genotypes. Read more.
Plasma microRNA Panel Detects HBV-Related Hepatocellular Carcinoma
Dec. 23 – Research shows a seven-marker microRNA panel accurately distinguishes patients with HBV-related hepatocellular carcinoma (HCC) from those with chronic hepatitis B or cirrhosis, and also from healthy individuals without liver dysfunction. Read more.
Hair Color for the Liver Conscious
Dec. 23 – For those living with HBV, consider making life easier on your liver by learning more about coloring options that are less toxic to your health. Read more.
Doctors Find Way to Detect Liver Cancer Earlier
Dec. 19 – New research out of Shanghai uses only one milliliter of a patient’s blood to determine if the patient has liver cancer and raises the accuracy of tests for early-stage liver cancer to nearly 90%. Read more.
Chronic Hep B Doubles Risk of AIDS Illnesses and Death in People Living With HIV
Dec. 19 – Chronic HBV infection nearly doubles the risk of AIDS or death in people diagnosed with HIV infection, compared with those only living with HIV. Early diagnosis and hepatitis B prevention are essential interventions. Read more.
Santa Clara County Looks at Liver Cancer Risk For Vietnamese
Dec. 19 – The booming Vietnamese community in Santa Clara struggles with a cancer rate of 32%. Screening and treatment of hepatitis B in the community would go a long way towards reducing the rate of liver cancer in the community. Read more.
Too Promiscuous to Donate an Organ? Maybe, CDC Says
Dec. 12 – According to new proposed guidelines by the CDC, deceased and living donors who were not monogamous in the previous 12 months before donation would be considered at risk of transmitting HIV, HBV and HCV. Read more.
House Members Urges Sebelius to Include People with HIV and Viral Hepatitis in the Affordable Care Act
Dec. 12 – Congresswoman Barbara Lee (D–CA), sent a letter signed by over 50 of her colleagues in the House of Representatives to Health and Human Services Secretary Kathleen Sebelius, urging her to include comprehensive services for people living with HIV and/or HBV and HCV in the final list of Essential Health Benefits in the Affordable Care Act. Read more.
Japan Parliament OKs Hepatitis B Patient Bailout
Dec. 12 – Japan's House of Councillors enacted a bill to provide government compensation to people infected with hepatitis B due to the re–use of syringes during mass vaccinations. Read more.
Prevalence [is Higher] of Chronic Hepatitis B Among Foreign-Born Persons Living In the United States by Country of Origin
Dec. 5 – A study published in Hepatology (Nov. 2011) suggests that the number of foreign-born persons living with chronic hepatitis B in the U.S. may be twice the number previously reported and that the total prevalence of chronic HBV may be 2.2 million. This suggests the need for screening of all foreign-born persons, so they can be identified, monitored and treated if necessary. Read more.
Studies of Patients with Cirrhosis Uncover Limitations in Liver Cancer Screening
Dec. 5 – Two studies available in the December issue of Hepatology have uncovered limitations in screening for hepatocellular carcinoma: the patient’s preference for surveillance rather than a randomized study, and screening at 3 month versus 6 month intervals did not improve the detection of small liver cancers. Read more.
Study Supports HBV Screening, Prophylaxis in Chemotherapy Patients
Dec. 5 – Researchers from M.D. Anderson Cancer Center in Houston state that when cancer patients have the hepatitis B virus, prophylaxis to prevent HBV reactivation during chemotherapy lowers their mortality, yet only 17% of patients in this study were screened for HBV despite CDC and other recommendations. Read more.
Hepatitis B on Rise Among Pregnant Women
Nov. 28 – The incidence of HBV among pregnant women in Vietnam has been increasing in recent years and timely detection is necessary to prevent it from being transmitted from mothers to newborns. Nearly 12 million Vietnamese are currently infected with HBV and the rate among pregnant women is 10–15%. Read more.
AASLD: HBsAg Clearance Increased When Patients Successfully Treated with Entecavir Switched to Peginterferon alpha–2a
Nov. 28 – Patients who sustained a virologic response to entecavir can achieve significantly higher HBsAg clearance when switched to a finite course of Peg IFNalpha–2a compared to those who remained on entecavir. Read more.
Liver Cancer Occurs in Immigrants With Hep B Younger than Screening Guidelines
Nov. 28 – Current recommended hepatocellular carcinoma screening guidelines for chronic HBV patients with cirrhosis and select non–cirrhotic populations may be inadequate for younger Asian Immigrant hepatitis B patients with a family history of HBV or a history of smoking. Read more.
Head of Miami VA Hospital Out Following Colonoscopy Scandal
Nov. 21 – The head of the Miami Veterans hospital has been replaced as a result of the colonoscopy scandal which potentially exposed 3,000 vets to hepatitis B and other infectious agents. Read more.
HHS Viral Hepatitis Action Plan: Spotlight on Hepatitis B
Nov. 21 – The needs of Americans living with chronic hepatitis B infections addressed in the new HHS Action Plan for Viral Hepatitis in the U.S. was featured in a special blog written by Dr. Ronald Valdiserri, Deputy Assistant Secretary for Health, Infectious Diseases at the U.S. Dept. of Health and Human Services (HHS). Read more.
AASLD: Patients at Risk for Hepatitis B Are Not Adequately Screened Before Receiving Chemotherapy Leading to the Preventable Reactivation of Hepatitis B Infection
Nov. 14 – Researchers at the University of Texas MD Cancer Center determined that only 20% of patients with newly diagnosed cancer who had hepatitis B risk factors were screened for HBV resulting in potentially poor outcomes for those with preventable, reactivated HBV. Read more.
AASLD: Long-Term Tenofovir for HIV/HBV Coinfection
Nov. 14 – Tenofovir showed long-term antiviral activity against HBV lasting 5 to 8 years, with minimal evidence of kidney toxicity, and steadily declining HBsAg levels over time. Read more.
Abbott’s New Hepatitis B Test is More Sensitive, Can Detect Mutant Virus Strains
Nov. 14 – Abbott’s new, highly sensitive diagnostic test for detection of hepatitis B surface antigen (HBsAg) has been approved for use in Europe. The high sensitivity of the new Abbott test enables clinicians to detect in patients very low levels of HBsAg, and viral mutant strains, as well as in donated blood and plasma. Read more.
High School Students Do Graduate Level Research on Liver Cancer and Hepatitis B
Nov. 14 – Two high schools students were finalists in the national Siemens Competition with a project that involved determining whether the HBV genome can be used to detect liver cancer at an early stage of the disease in order to improve survival rates. Michael Chen worked in the Hepatitis B Foundation’s research labs on this graduate school level project for the past two years with a fellow student, Kevin Chen (no relation). Read more.
NVHR Applauds Introduction of the Viral Hepatitis Testing Act of 2011
Nov. 7 – Landmark Viral Hepatitis Testing Act of 2011 is introduced into the House of Representatives, with a parallel bill introduced in the Senate aimed at preventing deaths from liver cancer through early detection of hepatitis B and C. Read more.
Gilead Announces Positive Five-Year Data Showing Effect of Viread® on Liver Fibrosis and Cirrhosis Caused by Chronic Hepatitis B
Nov. 7 – Five-year data from Gilead shows that Viread not only helps chronic HBV patients to achieve and maintain viral load suppression, but also has the potential to reduce or reverse liver damage. Read more.
Some People with Hepatitis B May Need Liver Cancer Screening Sooner and More Often
Nov. 7 – People with chronic HBV and other risk factors such as smoking and a family history of liver cancer should be screened sooner and more frequently. Read more.
Hepatitis Transmission Risk Needs to Be Studied in Nail Salons, Barbershops
Nov. 7 – An analysis presented at the American College of Gastroenterology (ACG) 76th Annual Scientific meeting questioned the adequacy of infection practices at hair and nail salons, and barber shops, and indicated there might be a potential for transmission of bloodborne pathogens, such as HBV and HCV. Read more.
Roche Receives FDA Approval for Acute Hepatitis B Test
Nov. 7 – Roche announced that the U.S. Food and Drug Administration (FDA) granted Premarket Approval for its IgM antibody to hepatitis B core antigen (Anti-HBc IgM) assay. The test represents the final component of the acute panel within the hepatitis test menu for the cobas 6000 series. Read more.
Panel Recommends Hepatitis B Vaccine for Diabetes Patients
Oct. 31 – Do you have diabetes? Get the hepatitis B vaccine, says the CDC’s Advisory Committee on Immunization Practices. Up to age 60, people with diabetes have twice the risk of hepatitis B as those without diabetes. Yet only 17% of those living with diabetes (and 26% of those without diabetes) have been fully vaccinated against hepatitis B. Read more.
New Research Shows Increased Hepatitis B Risk in Glucose Meters
Oct. 31 – An analysis conducted by the CDC found that patients with diabetes are at a significantly increased risk of hepatitis B infection. This is especially true for those living in long-term care facilities where HBV was transmitted through some aspect of the blood glucose testing process. Read more.
IDSA: Hep B Vaccine Benefit Persists in HIV Patients
Oct. 31 – The effects of the hepatitis B vaccine appear to last long-term in HIV-infected patients even if they have high CD4–positive cell counts. Read more.
HBV Screening Before Lymphoma Treatment Improves Outcomes, Is Cost-Effective
Oct. 31 – Researchers at the University of Toronto and St Michael’s Hospital presented compelling data at the annual meeting of the American Society of Clinical Oncology, which demonstrates screening all patients for HBV before initiating chemotherapy for lymphoma [to prevent potential reactivation] is associated with improved clinical outcomes and is economically favored. Read more.
Hmong Lack Education Resources to Combat Hepatitis B Infection
Oct. 24 – The lack of health awareness in the Hmong immigrant community coincides with a higher–than–normal incidence of hepatitis B. Read more.
Stricken Italian Tourist Leaves San Diego With New Liver
Oct. 24 – An Italian woman vacationing in California is leaving for home with a new liver from UCSD following a critical case of hepatitis B that left her comatose for almost two weeks. Read more.
San Francisco Leaders Unite to Call on Mayoral Candidates to End Hepatitis
Oct. 24 – San Francisco Hep B Free and the San Francisco Hepatitis C Task Force Campaign teamed up with the Asian American and LGBT community to call on the San Francisco mayoral candidates to determine their strategy to end the hepatitis epidemic. Read more.
European Studies On Risk of Hepatocellular Carcinoma
Oct. 24 – According to a cohort study published by the National Cancer institute, smoking, obesity, heavy alcohol consumption along with chronic hepatitis B and C contribute to a large share of hepatocellular carcinoma in Europe. Read more.
Thousands of Patients of Ottawa Clinic at Risk of HIV, Hepatitis
Oct. 17 – Ottawa Public Health is attempting to track down 6,800 people who may have been exposed to HBV, HCV and HIV viruses at an unnamed Ottawa clinic. Read more.
California Governor Signs Syringe Purchase and Needle Exchange Bills
Oct. 17 – California Governor Jerry Brown signed two harm reduction bills intended to decrease the transmission of blood-borne infections such as HIV and Hepatitis B and C among injection drug users. Read more.
Cage Warriors Implements Mandatory Blood Testing, Steroid Testing Possible in the Future
Oct. 17 – The U.K. based Cage Warriors organization has implemented its own mandatory blood testing for all fighters to identify infections such as HIV and hepatitis B and C. Read more.
Kagwe Girls Student Dies In School from HBV
Oct. 17 – A young student at Kagwe Girl's High School in Nairobi has died from hepatitis B related complications, allegedly after the school failed to take her to hospital in time. View YouTube news video.
Double Dose of Hepislav Works as Well as 3 Doses of Standard HBV Vaccine
Oct. 10 – Two injections of Dynavax’s investigational Hepislav HBV vaccine protected adults over age 40 as well as the standard regimen consisting of 3 doses of the Engerix–B vaccine given over 6 months, researchers reported at ICAAC. Read more.
Chinese Experts Working on New Ways to "Inject" Hepatitis Vaccines
Oct. 10 – Chinese scientists are developing new methods like spraying or dropping hepatitis vaccines into people’s noses to replace traditional injections in an effort to facilitate the country’s goal in controlling hepatitis B. Read more.
Team Approach Helps Tackle Health Disparities
Oct. 10 – A new pilot program in NYC for HBV screening, vaccination and low cost care is a great example of success when social agencies and medical facilities team up to offer culturally and linguistically appropriate care to fight disparities faced by disadvantaged minority communities. Read more.
Sanford Guide to Hepatitis Diagnosis and Treatment Available in Mobile App
Oct. 3 – The Sanford Guide to Hepatitis Diagnosis and Treatment is now available as a mobile app, the first of its kind for hepatitis B and C treatment, making it easy for healthcare professionals anywhere in the world to find the latest treatment guidelines instantly. Read more.
China: Where a Blood Test Determines Everything
Oct. 3 – Routine HBV testing of potential employees and students in China remains widespread more than a year after the nation banned mandatory testing, so numerous websites have sprung up offering “gunmen” for hire – uninfected people who charge $125-$300 to take the blood test for HBV-infected applicants. Read more.
Flares During HBV Treatment Do Not Predict Response, May Cause Liver Failure
Oct. 3 – Researchers report that hepatic flares, or sudden increases in liver enzymes or viral load while undergoing oral antiviral therapy for chronic HBV, did not increase sustained viral clearance and led to decompensated liver failure in some patients. Read more.
Med Students Not Adequately Protected Against Hepatitis B
Oct. 3 - Health care students are frequently exposed to blood-borne pathogens, placing them at increased risk for hepatitis B infection, but HBV vaccination rates are just below 60% among this population, which lag behind national recommendations. Read More.
Surgeons Object to New CDC Organ-Screening Guidelines
Sept. 26 – New CDC guidelines recommending that all organ donors be checked for HIV, HBV and HCV with the most sensitive screening method, known as nucleic acid testing, are raising concerns among transplant surgeons, who fear they may limit availability of organs. Read more.
Shark-Derived Drug May Treat Viruses
Sept. 26 – A unique compound originally isolated from sharks, known as squalamine, could prove to be a promising treatment for HBV and other viral diseases, researchers say, with human trials to hopefully begin within the next year. Read more.
Uganda: Medics Use ARVs to Treat Hepatitis B
Sept. 26 – Medical personnel have resorted to a desperate Plan B to treat hepatitis B after recommended drugs ran out of supply: they are now using anti-retrovirals (ARVs) meant for HIV. Read more.
Movie Puncture Exposes HBV, HCV, HIV Dangers in Needlestick Injuries for Nurses
Sept. 26 – Captain America star Chris Evans plays an attorney in the movie “Puncture” that highlights the enormous risks faced every day by nurses and healthcare workers exposed to dangerous pathogens (HBV, HCV and HIV) through accidental needlestick injuries on the job. Read more.
NJ Doctor Loses License After Hepatitis B Outbreak
Sept. 19 – New Jersey officials have revoked the license of an oncologist they say committed “gross and repeated acts of negligence” that led to an outbreak of hepatitis B among his patients. Read more.
AFP Levels Associated with HCC Survival
Sept. 19 – Although the AASLD did not include alpha-fetoprotein (AFP) testing in its most recent guidelines for HCC (liver cancer) screening, AFP testing was recommended at the 2011 Digestive Disease Week meeting. Read more.
Flares during HBV Treatment Do Not Predict Response, May Cause Liver Failure
Sept. 19 – Developing hepatic flares, or sudden increases in liver enzymes or viral load, while undergoing antiviral HBV therapy did not increase the likelihood of sustained viral clearance and led to decompensated liver failure in some patients. Read more.
New HBV Workshop Consensus Statement and Algorithm Published
Sept. 12 – The Hepatitis B Foundation's evidence-based algorithm and consensus recommendations for primary care providers on whom to screen for hepatitis B and when to pursue further evaluation and management was published as an online exclusive by the Journal of Family Practice (Sept. 2011, vol. 60). The recommendations were created by an expert panel of physicians in family and internal medicine, obstetrics, and pediatrics, and a leading nurse practitioner and physician assistant. Read Article.
Occult HBV Infection May Be the Cause of Unexplained Liver Cancer
Sept. 12 – Occult HBV may account for nearly three-quarters of patients with apparently unidentifiable causes for HCC. Read more.
FDA Approves Exalenz Liver Cancer Trial
Sept. 12 – Exalenz Bioscience Lt. has received FDA approval for a clinical trial of its non-invasive BreathID device for early diagnosis of hepatocellular carcinoma. Read more.
Cancer, Rheumatism Drugs Tied to Hep B Deaths
Sept. 12 – Officials of the Japan College of Rheumatology will issue an advisory regarding testing for HBV since 17 people who recovered from past hepatitis B infections died due to a sudden and acute reactivation of the virus in their bodies after taking newly introduced drugs to treat such conditions as rheumatism and blood cancer. Read more.
Cancer-Fighting Virus Shown to Target Tumors Alone
Sept. 5 – Researchers have shown for the first time that a single intravenous infusion of a genetically engineered virus can alert the immune system to seek and destroy cancerous cells in patients without harming healthy tissue. The experimental virus, JX–954, will next be tested in a trial of patients with liver cancer due to HBV. Read more.
Cost-Effective Perinatal HBV Transmission Prevention ID’d
Sept. 5 – In hepatitis B infected pregnant women, administration of lamivudine or HBIG in the third trimester is a cost-effective method for prevention of perinatal transmission of hepatitis B, according to a study published in the September issue of Obstetrics and Gynecology. Read more.
Disease Exposure Via Medical Devices a Growing Concern, CDC Says
Sept. 5 – In the past 10 years, at least 15 hepatitis B outbreaks have been associated with providers failing to follow basic principles of infection control when assisting with blood glucose monitoring. Because of underreporting and under-recognition of infection, the number of outbreaks likely has been underestimated, the CDC says. Read more.
Ask the Expert: Employer Says No to Providing Free Hepatitis B Vaccinations
Sept. 5 – Employers with employees having the potential for occupational exposure to bloodborne pathogens must make the HBV vaccine available at no cost to the employee, according to OSHA guidelines. Read more.
Autism Not Caused by Vaccines, IOM Report Concludes
Aug 29 – There’s convincing evidence that some vaccines can cause adverse effects, but autism isn’t one of them, according to a new report from the Institute of Medicine. Read more.
Refugees, Mass Casualties, and Hepatitis B Transmission
Aug 29 – A report about HBV transmission among injured Afghan refugees serves as a reminder of the pervasive nature of HBV as a global pathogen, and the role global migration plays in HBV epidemiology. Read more.
Surgical Gowns “Virus Risk”
Aug 29 – Hospitals have been urged to buy longer gowns for surgeons to wear while operating, after a study in New Zealand found their gumboots were commonly stained inside with blood splashed from patients that pose a risk for infection with HBV, HCV and HIV. Read more.
Saffron Shows Promise in Preventing Liver Cancer
Aug 29 – Research indicates that saffron has a significant chemopreventive effect against liver cancer through its antioxidant, anti-cancer, and anti-inflammatory properties. Read more.
Chinese Hepatitis B Carriers Face Widespread Discrimination
Aug 23 – Lost opportunities to segregation at meals. A heartbreaking look at HBV discrimination in China. View now.
49,500 Facebook Friends Raise Money For Deltona Man’s Liver Transplant
Aug 22 – Social media miracle saves the day for Florida man with hepatitis B and D in need of liver transplant. Read more.
Foundation Advocates National Strategy on Liver Health
Aug 22 – Ghana needs a national strategy on liver health as the country records and upsurge in hepatitis B infection. Read more.
Panacea Biotec’s HBV and DTP Vaccines Delisted from WHO List of Prequalified Vaccines
Aug 22 – Following a routine site audit conducted by a WHO team of vaccine manufacturer, Panacea, the EnivacHB, hepatitis vaccines and other DTP based vaccines have been removed from the list of prequalified vaccines. Read more.
Early HBeAg Decrease Predicts Response to Entecavir for Hepatitis B
Aug 15 – Decreases in hepatitis B “e” antigen (HBeAg) during the first 6 months of treatment with entecavir are a better indicator than hepatitis B virus DNA levels. Read more.
‘Yellow Manifesto’ Targets Increased Awareness on Hepatitis B
Aug 15 – The Philippines gets serious about HBV and institutes a manifesto aimed at imparting information on healthy lifestyle practices, stricter medical procedures, better access to hepatitis B treatment and protecting the rights of workers living with HBV. Read more.
Deferoxamine Shows Promise for Liver Cancer in People with Advanced Disease
Aug. 15 – Deferoxamine, a cancer drug that has an anti-proliferative effect on tumor cells, led to improvement of hepatocellular carcinoma (liver cancer) in 2 out of 10 patients with moderate-to-severe liver disease, according to researchers. Read more.
Hepatitis B Foundation Mourns Loss of Dr. Emmet Keeffe, Distinguished Hepatologist
Aug 11 – Dr. Emmet B. Keeffe, Professor Emeritus of Medicine, Stanford University, passed away on August 8, 2011 after a distinguished career in hepatology. He was a thought leader in the field of hepatitis B who grasped all aspects of this liver disease. We will miss his active involvement and support of the Hepatitis B Foundation, but most importantly, we will miss his vital contributions to the science and medicine of chronic viral hepatitis. Read more.
Woman Tours the Country to End Discrimination Against Hepatitis B
Aug 8 – A woman living with chronic hepatitis B uses unusual tact in her battle to raise HBV awareness and fight discrimination in China. Read more.
Inflammation Markers Linked to Liver Disease, Death in Coinfections
Aug 8 – Several studies have shown that HIV/HBV and HIV/HCV coinfected individuals experience more rapid liver disease progression, have higher mortality and respond less well to interferon-based therapy than people with viral hepatitis alone. Read more.
Battling Hepatitis in West Africa
Aug 8 – West African health experts are calling for governments to take the prevalence of hepatitis B and C more seriously, and to act to reduce the cost of treatment more effectively. Read more.
CAPAC Members Speak at White House “World Hepatitis Day” Event
Aug 1 – U.S. Rep. Judy Chu, Chairwoman of the Congressional Asian Pacific American Caucus (CAPAC), Rep. Mike Honda and Rep. Barbara Lee spoke at a White House event on July 28 in honor of the first official World Hepatitis Day. Read more.
Operations Research Models of Hepatitis B Prove Decisive in Treating Millions in US and China
Aug 1 – With hepatitis B infecting as many as 10% of people of Asian descent, operations researchers at Stanford collaborated with liver transplant surgeon Dr. Sam So to develop mathematical models that verified the cost effectiveness of hepatitis B screening, treatment and vaccination. Read more.
WHO Renews Push to Cut Hepatitis Infections in Babies in Asia
Aug 1 – Nine Asia Pacific countries will not meet a 2012 target to reduce hepatitis B infections among children to below 2%, according to the World Health Organization (WHO) which plans to intensify its fight against the disease by increasing birth dose vaccination rates. Read more.
Okyeame Kwame Foundation Screens 1,000 for Hepatitis [B]
Aug 1 – Okyeame Kwame Foundation, a humanitarian organization established by rapper Okyeame Kwame organized a free hepatitis B screening event in Accra, Ghana to mark 2011 World Hepatitis Day. Read more.
World Hepatitis Day at the White House: Live Streaming Video
July 28 1:00 PM EDT – Today marks the first official World Hepatitis Day established by the World Health Organization (WHO) to call for a renewed commitment against a silent but deadly epidemic. In the United States, World Hepatitis Day will be observed at a White House event and live streaming video will be provided in its entirety on CDC’s Viral Hepatitis Website.
President Obama Issues Proclamation for World Hepatitis Day
July 28 – In an historic move, President Obama has elevated hepatitis B and hepatitis C infections as a national public health priority with his Presidential Proclamation recognizing World Hepatitis Day. He is the first U.S. President to publicly express support for the needs of the more than 5 million Americans living with chronic hepatitis. Read the Presidential Proclamation on Hepatitis.
16 Million Filipinos Afflicted With Hepatitis B
July 25 – Approximately 16 million Filipinos – or 16% of the total population – are unknowingly afflicted with hepatitis B that is often detected only during pre-employment medical examinations, said doctors in a briefing held in advance of World Hepatitis Day on July 28. Read more.
Why the CIA's Vaccine Ruse Is a Setback for Global Health
July 25 – The revelation that the HBV vaccine was used as a ruse by the CIA to get DNA evidence from [Osama bin Laden’s] kids drew a quick and angry response from health experts: the Washington Post warned that the CIA's "reckless tactics could have catastrophic consequences" and Time outlined three reasons why this is bad news for public health. Read more.
Pure Disinfectant Gets Label Expansion [to Include HBV] July 25 – Federal regulators approved expansion of the list of organisms killed by Pure Bioscience disinfectant used in hospitals: the product label will continue to claim it kills HIV in 30 seconds after contact, and HBV and HCV within a minute. Read more.
Plea for ‘Swift Action’ on Hepatitis B at Morriston
July 25 - Managers at Morriston Hospital in Swansea, where a woman who contracted hepatitis B died, have launched an inquiry after 150 heart patients were potentially exposed to HBV. Read more.
Vaccination Ruse Used in Pursuit of Bin Laden
July 18 – In the months before Osama bin Laden was killed, the Central Intelligence Agency ran a phony HBV vaccination program in Abbottabad, Pakistan, as a ruse to obtain DNA evidence from members of Bin Laden’s family, according to an American official. Read more.
HBV Antivirals, Viral Breakthrough, and Drug Resistance
July 18 – Virological breakthrough is common among people taking oral antivirals for HBV, but nearly 40% are unrelated to drug resistance. Read more.
Fine Proposed For Deadly Hepatitis B Outbreak
July 18 – A state panel recommended a $16,000 fine for an assisted living center where six died from hepatitis B … but people who knew the hepatitis victims said the fine is not strong enough. Read more.
Treating HIV/HBV Coinfection in Africa
July 11 – Some antiviral drugs active against HBV/HIV coinfected patients are better than others, which highlights the “the urgent requirement for better management of HBV disease,” according to a recent study. Read more.
Viral Dominance in HBV/HCV Dual Infection
July 11 – As much as 20% of the world’s population has hepatitis B and hepatitis C dual infection, with Asian ethnicity a significant independent predictor of HBV-dominant disease in people with this dual infection. Read more.
HKU Announces Breakthrough in Liver Cancer Research
July 11 – The University of Hong Kong has identified tumor-producing cells capable of maintaining resistance to chemotherapy and resulting in recurrences of liver cancer, which will help improve treatment results. Read more.
MedMira to Make Quick Hep B Test for U.S. Army
July 11 – MedMira received a $2.2-million contract from the U.S. Army to develop and commercialize an HBV test that will provide diagnostic results in three minutes and identify both current and past infection with the virus. Read more.
US Govt Starts Hep B Campaign Among AAPIs
July 5 – The Obama administration has started an intensive information drive to discuss the risks, treatment and prevention of hepatitis B among Asian-Americans and Pacific Islanders (AAPIs). Read more.
Accord Must Be Step Toward Better Hepatitis B Care
July 5 – A basic agreement was reached in Japan over lawsuits in which people infected with hepatitis B through reused needles in group vaccinations asked the state to pay damages. Read more.
China’s Health Care Reform Looks to Science
July 5 – China's large-scale, health care reform effort referred to as “Chinacare” will tackle hepatitis B as one of its two disease priorities in 2011. Read more.
Entecavir Effective for Hepatitis B Patients with Liver Cancer
July 5 – Initial treatment with entecavir (Baraclude) monotherapy worked well in chronic hepatitis patients with hepatocellular carcinoma, lowering viral load and improving liver health. Read more.
Plaintiffs, Gov’t Reach Settlement Over Hepatitis B Infections
June 27 – On Tuesday, Prime Minister Naoto Kan, of Japan, will acknowledge the government’s responsibility for the infections and directly apologize to hepatitis B sufferers. Read more.
Nearly 15% of Country’s Paramedics Have Hepatitis B
June 27 – The highest number in Pakistan, 14.7%, of hepatitis B cases in hospital staff were found in paramedics across the country. Read more.
Gillespie Bill to Protect Police Officers Passes State House
June 27 – Legislation that would make it a crime to attempt to expose officers to communicable diseases such as hepatitis B or HIV unanimously passed the state House of Representatives. Read more.
ACIP Considers Hepatitis B Vaccine for Adults with Diabetes
June 27 – Hepatitis B vaccination of adults with diabetes could potentially prevent more than 5,000 hepatitis B infections, according to the CDC Advisory Committee on Immunization Practices. Read more.
Hepatitis B Outbreak in Swansea Investigated
June 20 – Health officials are investigating after an outbreak of hepatitis B in Swansea with 4 people having been recently diagnosed. In 2010 there were 200 confirmed cases in Wales, UK. Read more.
Causes of Death among People with Hepatitis B and C
June 20 – Deaths due to most liver-related causes dropped among people with hepatitis B and C; however, mortality due to liver cancer remains high, with monoinfected HBV individuals dying more often from liver cancer than those with HCV. Read more.
A Life Worth Living
June 20 – Two men who benefited from the NexPAP patient assistance programme for treatment of their liver cancer due to chronic HBV infections celebrate their ‘second-chance’ in life. Read more.
Central Falls Coverup - Students Not Properly Immunized
June 13 – A number of Central Falls middle school students over a six-year period were not properly immunized for hepatitis B, according to a former nurse who says she was punished for speaking out against the error and now is suing the school district. Read more.
Agenix Remains on Course to Apply for Hepatitis B Drug Clinical Trials in China
June 13 – The company plans to file a formal application with China’s State Food and Drug Administration in the second quarter of 2012, and anticipates approval to begin Phase I human studies in late 2012 for its lead Hepatitis B drug, AGX 1009. Read more.
FDA Labeling Change Interferon alfa-2b and Peginterferon alfa-2b
FDA approved a labeling change to the WARNINGS and PRECAUTIONS section, specifically, that PegIntron or Intron A should be used with extreme caution in patients with a history of psychiatric disorders. Read more.
Merck Donates Library to Hepatitis B Foundation’s Research Institute
June 6 – In a public ceremony today, Merck donated its entire “priceless” natural products library, along with an undisclosed grant, to the Institute for Hepatitis and Virus Research, which is the research arm of the Hepatitis B Foundation. The Merck donation is considered to be one to the most diverse and best curated natural products libraries in the world and represents approximately 60% of all known plant genera in the world. Read more.
Killing Us Softly: What Americans Don't Know & Why It Will Kill Them
June 8 – Huffington Post blog addresses viral hepatitis which has for too long been an epidemic that doesn't make headlines even though more than 5 million Americans are suffering from chronic HBV and HCV. Read more.
Untreated Hep B to Send Liver Cancer Rate Soaring
June 6 – Deaths from liver cancer are liable to triple in the next decade, with the rise largely caused by untreated hepatitis B infections, experts say. Read more.
94,000 Cops Tested for Hepatitis
June 6 – Tests for hepatitis B and C have already been completed for about 94,000 policemen while efforts are under way to complete the screening of the remaining cops to achieve 100%. Read more.
VA Infection Risk Leads to 12,000 Tests
May 31 – The Department of Veterans Affairs is under political fire because about 13,000 veterans have been warned in the last two years that their blood should be tested for potentially fatal infections after possible exposures by improper hygiene practices at five VA hospitals in Ohio, Florida, Georgia, Missouri, and Tennessee. Read more.
Pennsylvania's Urology Practice Notifies Patients About Reused Needles
May 31 – Urology Associates of Chambersburg, PA has mailed letters to patients who recently underwent prostate biopsies, alerting them of possible infection from reused needles during the procedure and the recommendation for hepatitis B, C and HIV testing. Read more.
Mother-to-Mother Milk Sharing Concept
May 31 – In 1980, due to transfer of hepatitis B and C, HIV and CMV infection through breast milk, breast milk banks were closed down. But now in Australia, the same concept has resumed, however, the milk is first screened for viruses, just like donor blood. Read more.
“B A Hero” Flash Mob Takes Over City Hall
May 24 – The HBF mobilized the Hep B Free Philadelphia coalition to host a public awareness event at Philadelphia’s City Hall to launch the “B A Hero” theme that promotes testing and vaccination in the fight against hepatitis B during May National Hepatitis Awareness Month! See more photos.
Take the Nordstrom HBV Survey Now to Stop Liver Cancer!
May 24 – It only takes 30 seconds of your time to answer a few simple questions and Nordstrom will donate $35 per survey to promote Hep B Free! The goal is to reach 10,000 by May 31 and we’re more than halfway there. Take the survey now!
Two Oral Hep C Drugs Approved
On May 13 the U.S. FDA approved Merck’s HCV protease inhibitor boceprevir (Victrelis), the first direct-acting hepatitis C drug. Read more.
On May 23 the U.S. FDA approved Vertex's HCV protease inhibitor telaprevir (Incivek), the second direct-acting hepatitis C drug launched this month. Read more.
HHS Announces Action Plan to Prevent and Treat Viral Hepatitis
May 16 - The U.S. Department of Health and Human Services launched its action plan to prevent and treat viral hepatitis, a silent epidemic affecting 3.5 – 5.3 million Americans. “These infections have fueled a tragic cascade of human suffering,” said Howard K. Koh, MD, MPH. “The new HHS action plan on viral hepatitis represents an unprecedented call to action for better education, treatment and prevention.”
The plan’s success is contingent on leadership of government at all levels and the active and informed participation of communities, non-governmental organizations, health care providers, and the private sector.
“No one government agency can fight viral hepatitis alone, and here at CDC, we believe this action plan will not only strengthen the work we’ve been doing, but help all of us across the government collaborate to take our nation’s prevention efforts to the next level,” said CDC Director Thomas R. Frieden, MD, MPH. “Far too many Americans are unaware of the serious impact of viral hepatitis and the devastating consequences that can result from leaving it untreated. The time for action is now.” Read more
HHS Announces Action Plan to Prevent and Treat Viral Hepatitis
May 12 – The U.S. Department of Health and Human Services today launched its action plan to prevent and treat viral hepatitis, a silent epidemic affecting 3.5 - 5.3 million Americans. Download Report
HHS Briefing on New Action Plan for Viral Hepatitis
May 12 – A briefing will be held at The National Press Club in Washington, DC on Thursday May 12 from 1:00 – 2:00 pm by Dr. Howard Koh, Assistant Secretary for Health and Human Services, to announce his new action plan to prevent, care and treat chronic viral hepatitis. Free and open to the public, so RSVP now!
Breastfeeding OK for Moms with Hepatitis B
May 8 – New mothers with hepatitis B can safely breastfeed their babies, as long as they take a few important precautions, according to a new study. Read more.
Alaska's History of Handling Hepatitis
May 8 – In the 1970s, Alaska had some of the nation's highest levels of hepatitis A and B infections. Nearly 40 years later, Alaska health care providers are world leaders in prevention, control and treatment of viral hepatitis, according to Dr. Brian McMahon who has led the effort in Alaska. Read more.
Screening for Hepatitis B May be Cost Effective for More of the Population
May 8 – Research at the University of Cincinnati provides evidence that current prevention and screening standards are worth the cost and may even need expansion to include more of the population, further helping prevent the spread of this life-threatening disease. Read more.
Switch to Lamivudine Not as Effective as Staying on Entecavir
May 8 – Hepatitis B patients who switch to cheaper lamivudine after achieving undetectable HBV viral load and normal ALT on entecavir are more likely to experience viral rebound. Read more.
HHS Briefing on New Action Plan for Viral Hepatitis
May 12, 2011 - A briefing will be held The National Press Club in Washington, DC on Thursday May 12 from 1:00 – 2:00 pm by Dr. Howard Koh, Assistant Secretary for Health and Human Services, to announce his new action plan to prevent, care and treat chronic viral hepatitis. Free and open to the public, so RSVP now!
Breastfeeding OK for Moms with Hepatitis B
May 8 – New mothers with hepatitis B can safely breastfeed their babies, as long as they take a few important precautions, according to a new study. Read more.
Alaska's History of Handling Hepatitis May 8 – In the 1970s, Alaska had some of the nation's highest levels of hepatitis A and B infections. Nearly 40 years later, Alaska health care providers are world leaders in prevention, control and treatment of viral hepatitis, according to Dr. Brian McMahon who has led the effort in Alaska. Read more.
Screening for Hepatitis B May be Cost Effective for More of the Population
May 8 – Research at the University of Cincinnati provides evidence that current prevention and screening standards are worth the cost and may even need expansion to include more of the population, further helping prevent the spread of this life-threatening disease. Read more.
Switch to Lamivudine Not as Effective as Staying on Entecavir
May 8 – Hepatitis B patients who switch to cheaper lamivudine after achieving undetectable HBV viral load and normal ALT on entecavir are more likely to experience viral rebound. Read more.
Rebound Common For Some Patients
May 2 – In clinical practice, the hepatitis B virus often rebounds in patients taking nucleoside or nucleotide analogues, researchers reported; however, the cause of the rebound may be poor drug adherence, not genetic resistance. Read more.
AAPCHO Releases New Hepatitis B Product Series
May 2 – The Association of Asian Pacific Community Health Organizations (AAPCHO) just released a three–part series, entitled “B Activated Resource Guide” that highlights successful hepatitis B programs Asian American, Native Hawaiian, and Pacific Islander Communities and provides a toolkit of information and resources to help reach out to policymakers and the media. Read more.
NIH Launches Web Resource on Complementary and Alternative Medicine
May 2 – A new online resource, designed to give health care providers easy access to evidence-based information on complementary and alternative medicine, was launched by the National Center for Complementary and Alternative Medicine (NCCAM) of the National Institutes of Health. Read more.
Passionate Hearts For Livers: Students Take Stand Against Hepatitis B
May 2 – Kevin Hur, a UC Berkeley student noticed the lack of hepatitis B services for low socioeconomic populations in the Oakland neighborhood, and with the support of other students and a community clinic initiated the creation of The Hep B Project that has to date provided screenings for almost 900 people. Read more.
Watch a Music Video and Raise Money for Hep B!
April 25 – For every view in the month of April that the indie rock band Rooftop Pursuit receives for their latest single "Why I Sing," which follows the story of a girl with hepatitis B, sponsors will each donate a penny towards the Hep B Free America campaign. View now!
Kidney Toxicity Uncommon among People Taking Tenofovir for Hepatitis B
April 25 – People taking tenofovir to treat chronic hepatitis B seldom experience kidney impairment, and this population does not appear predisposed to bone problems, according to researchers. Read more.
Thousands of VA Dental Patients Should Be Tested for HBV, HCV and HIV
April 25 – A task force recommends thousands of Dayton VA Medical Center patients be tested for exposure to hepatitis B, hepatitis C and HIV due to exposure from a dentist failing to change his gloves and sterilize equipment between patients. Read more.
Influenza and HBV Vaccination Coverage Among U.S. Health Care Personnel
April 25 – Influenza and hepatitis B vaccination coverage among health care personnel remain well below the Healthy People 2010 objectives with marriage being associated with influenza vaccination and higher education level s associated with hepatitis B vaccination coverage. Read more.
Watch a Music Video and Raise Money for Hep B!
pril 18 – For every view in the month of April that the indie rock band Rooftop Pursuit receives for their latest single "Why I Sing," which follows the story of a girl with hepatitis B, sponsors will each donate a penny towards the Hep B Free America campaign. View now!
Immune-Based Therapy GS-9620 Shows Promise for Hepatitis B
April 18 – Gilead's GS–9620, an experimental TLR7 agonist, stimulated interferon production and activated B–cells and T–cells in laboratory and human studies, and was active against hepatitis B, researchers reported at EASL 2011. Read more.
Bills Would Test Accused Rapists Sooner for HIV, Hepatitis B
April 18 – South Carolina’s legislature has passed two separate but similar bills that would enable survivors of sexual assault to require that their attackers be tested for HIV and hepatitis B within 48 hours of being charged or indicted. Read more.
First New Hepatitis B and D Treatment in Many Years
April 11 – Entry inhibitors that prevent hepatitis virus from entering liver cells represent a new mechanism of action that limit the issue of viral resistance and could provide new HBV and HDV treatments include SALPs and Myrcludex-B. Read more.
Asian Ethnicity May Predict Hep B-Dominant Dual Infection
April 11 – Asians who are co-infected with HBV and HCV are more likely to have hepatitis B-dominant disease, compared to co-infected non-Asians, according to a recent study in Hepatology. Read more.
FDA Approves Labeling Changes for Telbivudine
April 11 – The U.S. FDA has made changes to the labeling of the antiviral drug telbivudine that are "related to a higher risk of developing resistance-associated substitutions in treated patients." Read more.
PlantPharm Biomed on Target to Introduce First Plant-Based Oral Hepatitis B Vaccine
April 11 – There is global demand for a low-cost, shelf-stable, orally administered HBV vaccine and PlantPharm Biomed is seeking FDA approval of its vaccine produced completely in potato plants that has proven effective against HBV in Phase I human clinical trials. Read more.
The Hepatitis B Community Loses Cherished Friend and Advocate
April 6 – This is a sad day for the hepatitis B community. Fox Chase Cancer Center Senior Advisor and Hepatitis B Foundation Co-founder and Trustee Distinguished Scholar, Dr. Baruch S. Blumberg passed away on April 5, 2011. Read more.
Mongolia's Struggle with Liver Cancer
April 4 – Mongolia has the world's highest rate of liver cancer mortality - six times the global average - and the number is increasing due to high rates of hepatitis C and B infection along with widespread alcohol use. Read more.
Home Tattoo Kits ‘Are Putting Teenagers at Risk from Disease’
April 4 – Teenagers are putting themselves at risk of debilitating and potentially deadly blood diseases by buying “do it yourself” or DIY tattoo kits over the internet, which come with inks, needles and designs. Children have caught hepatitis from such kits, which are cheaper than visiting a professional, particularly if used several times. Read more.
Abbott Introduces Hepatitis B Sequencing Test in Europe
April 4 – The Abbott HBV Sequencing test has been approved for use in Europe, which is used to identify genomic sequences of the hepatitis B virus that offers physicians a highly precise method for managing HBV patients and select or change antiviral therapies based on known drug resistance of specific viral genotypes. Read more.
Public Campaign Ad Featuring HBV Patient Draws Criticism
April 4 – A new HBV awareness campaign, sponsored by the Korean Association for the Study of the Liver, has aired a TV advertisement that’s being criticized as too vivid and intense. Read more.
Dark Side to Children’s School Games
March 28 – Durban school children who are dabbling in occult practices have been warned that their activities, which start out as “games”, could lead to HIV/Aids and hepatitis infections and serious psychological trauma. Read more.
Hepatitis B Patients Increase in Korea
March 28 – A study done by Korea's National Health Insurance Corporation shows that more than 300,000 HBV patients visited the hospital in 2009 up 40,000 in 2006. Read more.
Board Says Doctor Admitted He Reused Biopsy Needle Guides
March 28 – The Nevada State Board of Medical Examiners (BME) recently suspended a doctor for allegedly reusing needle guides during prostate and rectal biopsies. Read more.
First Annual Meeting of the European Hepatitis B and C Surveillance Network
March 28 – Last week the first annual meeting was held to establish a network for hepatitis B and C surveillance by carrying out a survey on prevention and surveillance activities in the Member States. Read more.
Test All Chemo Patients for Hepatitis B
March 21 – Every cancer patient should be tested for HBV infection before starting chemotherapy since 5% to 40% of reactivation cases die of liver failure, said a Memorial Sloan Kettering oncologist at the National Comprehensive Cancer Network 16th Annual Conference. Read more.
China's Hepatitis B Market to Double by 2012
March 21 – The market for hepatitis B drugs in China is expected to grow 135% by 2012 - from $340 million in 2007, sales of HBV treatments will increase to $800 million over the five years, according to a new report from Decision Resources. Read more.
Employee Fear May Have Put Veterans’ Health At Risk
March 21 – A culture of fear may have kept workers and supervisors at the Dayton VA Medical Center’s dental clinic from disclosing the unsafe practices of one dentist over 18 years. Of the 535 patients who underwent invasive dental procedures and have now been tested, 7 patients are positive for HCV and 2 for HBV. Read more.
New Hepatitis B Surface Antigen Test Helps Assess Treatment Response
March 11 – Roche Diagnostics announced the launch of a new hepatitis B surface antigen (HBsAg) test to help clinicians evaluate patient response to treatment of chronic HBV infection. Reduction or clearance of HBsAg is one indicator of good response, along with decreased HBV DNA viral load. Read more.
More Liver-Related Death for HIV Coinfections with HBV than HCV
March 11 – HIV positive gay and bisexual men in the long-running Multicenter AIDS Cohort Study were significantly more likely to die of liver-related causes than HIV negative participants, and those coinfected with HBV had about double the risk of death than those with HCV. Read more.
Tulane Medical Center Puts Patients at Risk for HBV, HCV and HIV
March 11 – Hundreds of Tulane Medical Center's patients have received letters warning them they may have contracted HBV, HCV or HIV because the hospital didn't properly sterilize their equipment used for different GI procedures. Read more.
HBV Infection Decreases Risk of Liver Metastasis in Colorectal Cancer Patients
March 11 – A new report looks at the link between HBV infection and liver metastasis of colorectal cancer and results showed a decrease in the number of metastases in the HBV infected group (14.2%) compared to the non-infected group (28.2%). The authors suggest that HBV infection could be used as a prognostic factor in terms of whether liver metastasis will occur in colorectal cancer patients. Read More.
Pregnant Women in China to be Tested for HBV
March 2 – Starting this year, pregnant women across China will receive free screenings for HIV, syphilis, and HBV. If they test positive, they will be treated at hospitals to prevent them from transmitting the diseases to their children. The Ministry of Health will spend at least $106 million a year on this program. Read more.
Prevalence of Acute HBV Higher Among Adults with Diabetes
March 2 – Data presented at the Advisory Committee on Immunization Practices meeting shows that incidence of acute hepatitis B is significantly higher among adults with diabetes compared to those without diabetes, especially in those aged 23 to 59 years. Read more.
Hep B Free Las Vegas!
March 2 – Hep B Free Las Vegas has been launched with a former Las Vegas headliner as the face of the new campaign to advocate for hepatitis B screening and vaccination. At the launch event, coalition coordinator Aurora Wong urged the National Federation of Filipino American Associations to coordinate screenings to reach the 80,000 Filipino-American residents of Southern Nevada. Read more.
Medicare May Pay for STD Tests for Sexy Seniors
March 2 – As Americans live longer, they are sexually active for a longer period of time; therefore, preventative care is important and Medicare might pay for STD tests for diseases such as syphilis and hepatitis B. Currently Medicare pays for HIV tests. Read more.
Benitec Hepatitis B RNAi Drug Program Moves to Next Stage
Feb. 24 – Benitec announced that following the success of the first stage of its antiviral program to develop an RNA interference (RNAi)-based therapy against HBV it has reached an agreement with Biomic to proceed to the next stage of pre-clinical studies. Read more.
Hepatitis B Vaccination Still India’s Challenge
Feb. 24 – In India, surveys indicate that around 30 million people are infected with hepatitis B but with a cheap and effective vaccine, millions of lives could be saved. Read more.
Tenofovir Remains Effective against HBV after 5 Years in HIV Coinfected Patients
Feb. 24 – Tenofovir continues to potently suppress both HBV and HIV in coinfected patients for at least 5 years, according to a recent which supports guidelines recommending that HIV/HBV coinfected people should receive drugs with dual action against both viruses. Read more.
President’s Budget Includes $5 Million Increase at CDC for Viral Hepatitis
Feb. 14 – The Obama Administration released its 2012 budget that includes a $5MM increase for the CDC’s Division of Viral Hepatitis to expand state surveillance, screening and treatment programs. Read more.
Study Finds HBV 10 Times Likelier In Koreans
Feb. 10 – Korean-Americans living in North Jersey are at least 10 times more likely to have the hepatitis B virus than the general population, according to a screening program finished late last year. Read more.
VA to Test 535 Dental Patients for Infections
Feb. 10 – At least 535 patients of a Veterans Affairs dental clinic in Dayton, OH will be offered free testing for blood-borne infections, including HBV, after it was discovered that a dentist there failed to change gloves or sterilize instruments between patients. Read more.
Possible Risk of HBV Transmission During In Vitro Fertilization
Feb. 10 – A study to define the risk of HBV transmission through oocytes and embryos from chronic HBV carriers resulted in data that suggests the possibility of vertical transmission of HBV via the germ line. Read more.
53 Patients Injected with Same Needle
Feb. 10 – Fifty-three people on the NSW Central Coast could have been exposed to HIV, HBV and HCV after they received injections using the same needle. Read more.
Some Vaccines May Protect Children Against Cancer
Feb. 4 – A study in J. of Pediatrics showed that children born in areas where most children had been vaccinated for hepatitis B had about 20 percent lower odds of all types of childhood cancer than those born in areas where fewer were vaccinated. Read more.
Shot At Life: All Newborns to Get HBV Vaccine
Feb. 4 – The New Delhi, India health ministry has finally given the go-ahead to introduce the shot in its national immunization program and is in the process of procuring 100 million doses of hep B vaccine since there are 26 million births annually. Read more.
An Estimated 10,000 Births to HBV-Infected Women Were Missed
Feb. 4 – According to a CDC study that estimated births to HBV-infected women in 22 states during 2006, approximately 10,000 births to HBV-infected women were not identified by the state and local health departments. Read more.
Jan. 28 – On January 28, 2011 the Hepatitis B Foundation was officially incorporated as a 501(c)3 nonprofit organization in New Hope, PA. Today, we are proud to be celebrating our 20th anniversary as the only national nonprofit research and disease advocacy organization solely dedicated to hepatitis B! Read more.
Nucleic Acid Testing Detects HBV Sooner in Donated Blood
Jan. 28 – Use of nucleic acid testing, which directly detects hepatitis B virus genetic material in the blood, can identify people with potentially infectious virus earlier than tests that look for anti–HBV antibodies, according to an analysis of nearly 4 million donated blood samples. Read More.
New HBV Legislation to Protect Emergency and Law Enforcement Officers
Jan. 20 – Pennsylvania state senator Stewart Greenleaf introduced new legislation (SB 133) to provide HBV screening, diagnosis, treatment and follow-up for first responders and state and local law enforcement officers on January 12. Read Senate Bill 133.
New Emergency and Law Enforcement Officer HBV Vaccination Bill
Jan. 20 – Pennsylvania state senator Stewart Greenleaf introduced legislation (SB 133) to provide HBV screening, diagnosis, treatment and follow-up for first responders and state and local law enforcement officers on January 12. Read Senate Bill 133.
Man Discovers Transplant Patients Face Huge Costs
Jan. 18 – Dale Shaylor, a Deltona father of three who has hepatitis B, journeyed to Florida in search of a life-saving liver transplant, only to find the surgery has a price tag far out of the missionary pilot's reach. Read more
Healthcare Stumbling in Indonesia’s Hepatitis B Fight
Jan. 18 – Poor access to healthcare means that most Indonesians infected with hepatitis B do not get treatment – or even know they have the disease – because of a lack of facilities and trained healthcare personnel. Read more.
Government Considering Hepatitis B Relief Fund
Jan. 18 – The Japanese government will seek to have a bill jointly sponsored to create a 1 trillion yen relief fund for hepatitis B patients and asymptomatic carriers believed to have contracted the disease through group vaccinations. Read more.
Successful Citywide Prevention Campaign to be Replicated
Jan. 18 – New research findings demonstrate that the San Francisco Hep B Free campaign has increased awareness, testing and vaccination for chronic hepatitis B – a silent killer and the leading cause of liver cancer – in the city's Asian and Pacific Islander community. Read more.
Bill Would Protect Police From Body Fluids Assault
Jan. 12 – A state senator in Nebraska has introduced bill designed to protect police from assault with bodily fluids that can transmit diseases such as HIV and hepatitis B or C. Read more.
Guidelines on Hepatitis B in Workplace Issued by Philippine Government
Jan. 12 – To prevent the spread of HBV in the workplace without discriminating against infected workers, the Philippine Department of Labor and Employment issued a seven-point guideline on dealing with the situation. Read more.
36 Millions Indians Suffer from Hepatitis B
Jan. 12 – The number of Indians infected with and succumbing to HBV has increased with the country ranking second in the list of countries with the most hepatitis. Read more.
Hep B Organ Recipient Shares Good Word About Gift of Life
Jan. 3 – Roughly ten years into his career, Dr. Hagan contracted hepatitis B from a patient, and after three relapses was put on a transplant list. He still remembers the first time he met his donor family and says it’s one of the single most important experiences of his entire life. Learn more.
New Study Upends Thinking About How Liver Disease Develops
Jan. 3 – researchers present a new and more definitive explanation of how fibrotic cells form, multiply and eventually destroy the human liver, resulting in cirrhosis which includes the existence of a previously unknown kind of inflammatory white blood cell. Learn more.
Dynavax Reports Phase 1B Results for Hepatitis B Therapy Candidate
Jan. 3 – Dynavax Technologies reported safety and immunogenicity data from its Phase 1b clinical trial of DV-601, its proprietary hepatitis B therapeutic vaccine, which may offer an alternative therapeutic option for patients chronically infected with HBV. Learn more.
Government Proposes Raising Amount of Damages for Hepatitis B Sufferers
Dec. 27 – The Japanese government has proposed raising the maximum amount of damages for the families of individuals who were infected with hepatitis B through mass vaccinations almost 20 years ago and are now suffering from liver cancer or end-stage cirrhosis (or have died). Read Full Article.
Artificial Liver Device Improves Survival for Hepatitis B and C Patients with Decompensated Disease
Dec. 27 – An artificial liver device known as ELAD – which runs a patient's blood through cartridges containing human liver cells – conferred a significant survival advantage for people with acute decompensated liver disease related to chronic hepatitis B or C, according to a Chinese study. Read Full Article.
Is Chronic Hepatitis B Being Undertreated in the United States?
Dec. 15 – Despite the fact that there are up to 2 million Americans chronically infected with HBV, fewer than 50 000 people per year receive prescriptions for HBV antiviral medications, according to a new Hepatitis B Foundation publication. Learn more.
Is Chronic Hepatitis B Being Undertreated in the United States?
Dec. 15 – Despite the fact that there are up to 2 million Americans chronically infected with HBV, fewer than 50 000 people per year receive prescriptions for HBV antiviral medications, according to a new Hepatitis B Foundation publication. Learn more.
Is Chronic Hepatitis B Being Undertreated in the United States?
Dec. 15 – Despite the fact that there are up to 2 million Americans chronically infected with HBV, fewer than 50 000 people per year receive prescriptions for HBV antiviral medications, according to a new Hepatitis B Foundation publication. Learn more.
Patient Voices Features Hepatitis B Stories
Dec. 15 – Three adults living with chronic hepatitis B in the U.S. are now sharing their videotaped stories on Patient Voices featured on the New York Times website. Listen now.
Does Previous Hepatitis B Exposure Increase Liver Cancer Risk?
Dec. 15 – Researchers find that people who were previously exposed to HBV have an increased likelihood of developing hepatocellular carcinoma (HCC or liver cancer) even if they clear the virus, which suggests these individuals could benefit from regular liver cancer monitoring as well as those chronically infected. Learn more .
New Treatments for Hepatitis B
Dec. 8 – A researcher and his team at the University of Alberta have discovered a new class of drugs that could one day be used to treat people with hepatitis B. Read Full Article.
NPR Radio Show Features Hepatitis B
Dec. 8 – NPR Host Michel Martin of "Tell Me More" featured an interview about hepatitis B and liver cancer with Dr. Jennifer Lee, Hepatitis B Initiative of Washington, DC, and Leslie Hsu Oh, co-founder of the Hepatitis B Initiative of Boston. Download Interview.
Alcohol and Diabetes Increase Risk of Liver Disease Progression in Hepatitis
Dec. 8 – Researchers at Kaiser Permanente in California followed 12,000 adult HBV patients for at least 2 consecutive years during 1999-2007 and data suggests that alcohol contributes to the risk of liver cancer and both alcohol abuse and diabetes contribute to the risk of decompensation. Read Full Article.
Does Antiviral Therapy for Hepatitis B and C Prevent Hepatocellular Carcinoma?
Dec. 8 – A research study indicates that treatment might be of greater benefit if instituted earlier in the course of chronic HBV in order to prevent progression to liver cancer. Read Full Article.
Typical Acetaminophen Dose No Threat to Kids' Livers
Dec. 1 – Concerns about liver injuries in kids who take the common painkiller acetaminophen (Tylenol) are unfounded, researchers reported. With more than eight million American kids taking the drug every week, acetaminophen is the nation's most popular drug in children. Read Full Article.
Hospital's Transplant Program a Big Draw for Hispanics
Dec. 1 – Hispanics in Americas see a high incidence of obesity, hepatitis B and C, all of which may lead to organ transplants. Northwestern Memorial Hospital in Chicago has the only known transplant program conducted all in Spanish in the U.S. Read Full Article.
Effectiveness of Tenofovir in Real-world Clinical Practice
Dec. 1 – Tenofovir produced good HBV suppression in routine clinical practice, indicating that clinical trial outcomes extend to real life, according to findings presented at the recent AASLD 2010 meeting. Read Full Article.
Anti-HIV Pill Protects Against AIDS
Nov. 23 – For the first time, a study has demonstrated that taking a combination anti-HIV pill (Truvada) can protect uninfected people from contracting the AIDS virus through sex with transmission rates cut nearly in half. Read Full Article.
Health Inquiry: Negligence Led to Hepatitis B Scare
Nov. 23 – Negligence on the part of staff at a free dental clinic contributed to an HBV outbreak that infected five people last year, and put nearly 2,000 people in five states and the nation's capital at risk. Read Full Article.
HBV Vaccination Included in 2011 Medicare Rules
Nov. 23 – Traditional Medicare will pick up the tab for certain preventive care services, including annual wellness visits, the hepatitis B vaccine, mammograms and colorectal cancer screenings. Read Full Article.
Arizona Man Denied Life-Saving Liver Transplant
Nov. 17 – Felix was in the surgery room, prepped and ready for his life-saving liver transplant when doctors told him the state's Medicaid plan wouldn't cover the procedure due to recent cuts in funding for some services such as liver transplants. Read Full Article.
Source of North Carolina Hepatitis B Outbreak Revealed
Nov. 17 – State officials confirmed that investigators believe the improper use of blood glucose level testers are most likely behind the cause of a hepatitis B outbreak at a Mount Olive, North Carolina, nursing home that killed 5 residents. Read Full Article.
BMS Enhances Co-Pay Assistance Program for HBV Drug Entecavir
Nov. 17 – Bristol-Myers Squibb (BMS) expanded its co-pay benefit program for individuals receiving or wishing to use entecavir who have private insurance policies with out-of-pocket costs and will save eligible patients up to $200 per month for 4 years. Read Full Article.
Dr. Howard Koh: National Strategy for the Control of Viral Hepatitis and Liver Cancer
Nov. 10 – Dr. Howard Koh, the Assistant Secretary for Health, described the steps the U.S. administration is taking in response to the recent Institute of Medicine (IOM) report on viral hepatitis in his President's Choice Lecture at The Liver Meeting 2010, the annual meeting of the American Association for the Study of Liver Diseases (AASLD). Read Full Report.
Telbivudine and Elective Cesarean Section Help Prevent Perinatal HBV Transmission
Nov. 10 – Treatment with telbivudine (Tyzeka) and elective C-section births both reduced the likelihood of HBV transmission from mothers to infants during pregnancy and delivery, according to two separate research reports. Read Full Article.
Breastfeeding and Chronic HBV
Nov. 10 – A new study reviews current data about preemptive antiviral therapy during pregnancy and breastfeeding with an eye towards assessing safety and the long-term follow up of breast-milk HBV concentrations and correlation with serum viral load. Read Full Article.
Which Pegylated Interferon alfa-2b Regimen Works Best for Chronic HBV?
Nov. 10 – A Chinese study reported that patient with e-antigen negative chronic HBV respond best to PegIFN alfa-2b at 1.5 mcg/kg/week for 48 weeks, compared with a lower dose and/or shorter duration. Read Full Article.
From Podium to Practice: Updates in HBV Treatment from AASLD
Nov. 2 – Capsule Summaries from the 2010 Annual Meeting of the American Association for the Study of Liver of key oral and poster presentations have been selected by leading experts in the field. Read Full Article.
China Earmarks 800 Million Yuan for Mother-to-Child Transmission Prevention
Nov. 2 – China has designated more than 800 million yuan (US $120 million) for efforts to prevent mother-to-baby transmission of HIV, syphilis, and HBV, which is a 10-fold increase above 2009, which addressed only perinatal HIV transmission. Read Full Article.
Men Make Better Liver Donors
Nov. 3 – Men may be higher-quality liver donors than women, potentially a result of differences in life expectancy and causes of death, researchers report. Read Full Article.
Dr. John Ward: Screening Asian Patients for Chronic Hepatitis B
Nov. 3 – Dr. John Ward, Director of the Division of Viral Hepatitis at CDC, speaks about the expanded HBV screening recommendations for Asians living in the U.S. View CDC Expert Commentary Series.
Police Snatch Two HBV Runners from Beijing Marathon
Oct. 26 – Two runners were pulled out of the Beijing Marathon and held for questioning by police for advocating against the discrimination of hepatitis B sufferers. Almost 30 runners wore green vests with the slogan "Eliminating HBV (discrimination) is still on the way." Read Full Article.
Cluster of Hepatitis B Cases Kills Four at Nursing Home
Oct. 26 – State and local health officials are investigating a series of deadly hepatitis B cases in North Carolina at a senior assisted living center that have killed four residents. Read Full Article.
National Pediatric HBV Treatment Recommendations Published by Expert Panel
Oct. 26 – An expert panel of nationally recognized pediatric liver specialists convened by the Hepatitis B Foundation established the first national recommendations for the treatment of children with chronic hepatitis B virus (HBV) infections that was published in Hepatology (online). Read Full Article .
Major 4,000 Patient Study Validates GP73 Biomarker for HCC Detection
Oct. 26 – An NIH registration trial with 4,000 individuals has validated GP73 (discovered by Hepatitis B Foundation scientists) as an accurate serum marker for the detection of HCC and its recurrence after surgery with higher sensitivity and specificity than AFP. The researchers also recommend that GP73 measurement should be implemented in the clinic as a standard test for HCC. Read Full Article .
HM Cycling Club Fights Hepatitis B
Oct. 18 – A three member team will embark on a two week cross-country cycling tour of Ghana to educate people on the dangers of hepatitis B and to promote testing. Read Full Article.
Hep B Drug Gets New Indication
Oct. 18 – The U.S. FDA has approved the chronic hepatitis B drug entecavir for adult patients with evidence of liver decompensation, a typically difficult group to treat. Read Full Article.
Experts Rally for European Commitment to Halt Hepatitis B and C Epidemic
Oct. 18 – Leading physicians, scientists and patient groups demanded policy action from European Union officials to halt the epidemic of viral hepatitis. Read Full Article.
Vaccines: A New Alternative for Cancer Treatment
Oct. 18 – Cancer continues to affect millions of Americans each year…and one of the newest treatment modalities warranting a closer look is the use of vaccines for cancer treatment. Read Full Article.
Major 4,000 Patient Study Validates GP73 Biomarker for HCC Detection
Oct. 11 – An NIH registration trial with 4,000 individuals has validated GP73 (discovered by Hepatitis B Foundation scientists) as an accurate serum marker for the detection of HCC and its recurrence after surgery with higher sensitivity and specificity than AFP. The researchers also recommend that GP73 measurement should be implemented in the clinic as a standard test for HCC. Read Full Article.
New Treatment Recommendations for Children with HBV
Oct. 11 – An expert panel of pediatric liver specialists convened by the Hepatitis B Foundation established consensus recommendations regarding selection of children who may benefit from treatment, appropriate timing of treatment, and the choice of antiviral therapy (published in Oct. Hepatology). Read Full Article.
New Deadly Types of Virus Found in Papua
Oct. 11 – Scientists announced recently the discovery of three new subtypes of the hepatitis B virus in Papua where four infected patients are now receiving extensive treatment. Read Full Article.
Majority of Baby Boomers Not Concerned About Contracting STD's
Oct. 11 – When it comes to the birds and the bees, a recent study suggests some baby boomers aren't practicing what they preach and are taking too many risks; thus, are at increased risk for sexually transmitted diseases, including hepatitis B. Read Full Article.
AASLD and Trust for America's Health Call for Action
on Hepatitis B and C
Oct. 5 – HBV & HCV: America's Hidden Epidemics examines how new measures included in the Patient Protection and Affordable Care Act (ACA) combined with scientific advancements could be used to spare the lives of millions of infected Americans…and lead to billions of dollars in health care savings. Read Full Article.
Researchers Find 19 Million-Year-Old Genomic Fossils of Hepatitis B-Like Viruses in Songbirds
Oct. 5 – Biologists have uncovered virus fragments from the same family as the modern Hepatitis B virus locked inside the genomes of songbirds such as the modern-day zebra finch. Read Full Article.
CDC Chief Picks 6 'Winnable Battles' in Health
[and Hepatitis is not Included]
Oct. 5 – Dr. Thomas Frieden has chosen six priorities, or "winnable battles," that include smoking, AIDS, obesity/nutrition, teen pregnancy, auto injuries and health care infections, which has invigorated some, infuriated others. Read Full Article.
High HBV Awareness, Low Action Among Asian Americans
Sept. 27 – A new study reveals that despite high awareness about hepatitis B among Asian American providers, screening rates are still low and only 40% were familiar with current treatment guidelines; and in the community, there is also high disease awareness, but more education is still needed about prevention and treatment. Read Full Article.
National Hep B Community Gathers in San Francisco to Honor Nobel Laureate Dr. Baruch Blumberg and SF Hep B Free
Sept. 27 – Nobel Laureate Dr. Baruch Blumberg, discoverer of the hepatitis B virus and first vaccine, was honored with the 3rd Annual San Francisco Hep B Free Super Hero Award at its gala event co-chaired by Chinese Hospital and produced by AsianWeek Foundation. Read Full Article.
Nearly 20% of New HBV Infections May Occur in Healthcare Settings
Sept. 27 – As many as 1 in 5 cases of acute HBV infection in the U.S. may be attributable to exposure in healthcare settings, especially long-term care facilities, according to research presented last week at the 50th ICAAC meeting. Read Full Article.
Texas Children's Hospital Conducts First Study to Record Hepatitis B Incidence in Houston Children
Sept. 21 – Physicians will begin a study to estimate the true incidence and distribution of hepatitis B in children living in Houston. Read Full Article.
Hepatitis B Prevention Program Gaining Traction in San Francisco
Sept. 21 – A unique community-based program aimed at preventing hepatitis B in the high-risk Asian population is effectively combining provocative advertising with electronic medical records (EMRs) to maximize its success. Read Full Article.
Obesity Key Cause of Liver Problem in India
Sept. 21 – Obesity, combined with a high prevalence of hepatitis B and C, is contributing to a steep rise in liver problems and liver transplants in India every year. Read Full Article.
New National Hepatitis B and Liver Cancer Campaign Launched
Sept. 14 – The U.S. Office of Minority Health, Hepatitis B Foundation and AAPCHO are launching a new campaign to address the growing epidemic of hepatitis B and liver cancer that affects up to 1 million Asian Americans in a new television PSA campaign. Read Full Article.
Laotian and Hmong Americans Suffer Liver Cancer Disproportionately
Sept. 13 – Laotian and Hmong Americans have higher numbers and are more than twice as likely as other Asian Americans to die of hepatitis B and liver cancer as result of being diagnosed at later stages and less likely to receive treatment, reported UC Davis researchers. Read Full Article.
Meat and Fat Intake Associated with Liver Disease and Liver Cancer
Sept. 13 – A new study suggests that red meat and saturated fat may be associated with increased risks for chronic liver disease and hepatocellular carcinoma (primary liver cancer), whereas white meat may be associated with reduced risk. Read Full Article.
Renowned Liver Expert Robert G. Gish Joins UC San Diego Health System
Sept. 13 – Robert G. Gish, MD, world-renowned Hepatologist, has been recruited to the U. California San Diego School of Medicine to co-direct the Center for Hepatobiliary Disease and Abdominal Transplantation (CHAT), a multidisciplinary program designed for adult and pediatric patients. [Dr. Gish serves on the Hepatitis B Foundation's Medical and Scientific Advisory Board]. Read Full Article.
FDA Approves Abbott's Automated Hepatitis B Viral Load Test
Sept. 7 – The Abbott RealTime HBV assay for measuring HBV viral load was approved by the U.S. FDA as the first and only approved test capable of automating HBV viral load testing from sample extraction to final results. Read Full Article.
New Partnership Forms to Address Hepatitis Epidemic in Europe
Sept. 7 – A unique Partnership has formed to drive the first European Union–wide initiative to address the needs of the more than 23 million EU citizens currently living with hepatitis B or C comprised of key international public and private stakeholders. Read Full Article.
Cirrhosis Outcomes Better When Treatment Guidelines Followed
Sept. 7 – Current guidelines recommend screening liver cirrhosis patients for esophageal varices and beta-blocker treatment or variceal ligation, along with periodic follow-up endoscopy, for lower-than-expected rates of variceal hemorrhage. Read Full Article.
Bloodborne Pathogens and Their Threat to School Safety
Aug. 30 – According to the CDC, while there are 300,000 new cases of exposure to bloodborne diseases reported each year, the greatest risk to school personnel is from the hepatitis B virus. Read Full Article.
Meta-analysis Finds Tenofovir and Entecavir Are Most Effective Antiviral Drugs for Chronic Hepatitis B
Aug. 30 – A systematic review revealed the oral antiviral drugs tenofovir and entecavir demonstrated the most potent activity against HBV and its consequences in HBeAg positive patients during the first year of treatment. Read Full Article.
Fingerstick Device Infection Warning Issued by FDA and CDC
Aug. 30 – Federal regulators are warning nursing homes, hospitals and health care providers that they are seeing an alarming number of hospital infections, most notably hepatitis B, caused by the use of fingerstick devices (such as glucose monitors) on multiple patients. Read Full Article.
Fargo Shows Promise as Vaccine Center
Aug. 30 – The fledgling Center for Biopharmaceutical Research and Production at North Dakota State University, headed by Dr. Satish Chandran, seeks to establish Fargo as a center for developing biotechnology products and vaccines such as a therapeutic vaccine to treat hepatitis B. Read Full Article.
American Cancer Society Encourages Asians to Get
Screened for Hep B
Aug. 23 – The American Cancer Society is teaming up with the Salvation Army to offer free hepatitis B screenings as a result of the AMA statement that Asian and Pacific Islanders have the highest rates of the disease, which can lead to liver cancer if not treated. Read Full Article.
No Deportation for Expats with Hepatitis
Aug. 23 – New expatriate workers in the United Arab Emirates who are found to have hepatitis B when they undergo their medical test will not be deported but will be given treatment, according to the Ministry of Health. Read Full Article.
Hepatitis Carriers Will Get Right to Be Teachers
Aug. 23 – Hepatitis B carriers in Beijing will now be able to work as kindergarten teachers in the future, as authorities have cancelled restrictions against them. Read Full Article.
New Campaign for Hep B and C Tests in Pharmacies
Aug. 23 – Those working in pharmacy jobs may soon be part of a new screening and vaccination service for hepatitis B and C, thanks to a new campaign. Read Full Article.
Kerry & Honda: Disrupting a Deadly Disease
Aug. 16 – Sen. John Kerry (D-Mass.) and Rep. Michael Honda (D-Calif.) write in a Washington Times opinion piece that viral hepatitis is "more common than HIV/AIDS" and is "the leading cause of liver cancer – thus, Kerry has sponsored a bill (S3711) in the Senate, based on the bill that Honda sponsored (H.R.3974) in the House that would boost funding for prevention, surveillance and education programs related to the viruses. Read Full Article.
Treating Hepatitis B Runs Up Against Hmong Culture
Aug. 16 – In the Hmong/Laotian community, 17% have hepatitis B and most don't know they are infected; however, even if they did, they wouldn't treat it because they believe diseases are viewed as a spiritual problem. Read Full Article.
Long-Term Entecavir Therapy Results in Reversal of Fibrosis/Cirrhosis in HBV
Aug. 16 – The majority of nucleoside-naive patients with chronic hepatitis B who were treated with entecavir in a long-term study achieved substantial histological improvement and regression of fibrosis or cirrhosis. Read Full Article.
Sherburne to Vaccinate Adults without Full Health Coverage
Aug. 16 – Stimulus funds will be used by the Minnesota Department of Health will be used to vaccinate eligible adults who are uninsured or underinsured, including hepatitis B. Read Full Article.
Kerry Pushes $600 Million Bill to Create National Hepatitis Strategy
Aug. 6 – U.S Senator John Kerry introduced a sister bill to HR 3974 to authorize funding of almost $600 million over five years to combat the hepatitis B and C, which affects more than 5 million Americans. Read Full Article.
Doctors Target Hepatitis B in Boston's Chinatown
Aug. 6 – Targeting hepatitis B, known as the “silent killer,” a group of local doctors will provide outreach in Boston's Chinatown as part of an effort by the local chapter of Liver Health Project, started by Harvard students. Read Full Article.
Grim numbers on World Hepatitis Day
Aug. 2 – A staggering number of Indonesians — as many as 30 million people — are infected by hepatitis, said the government and researchers at events for the country's first observance of Hepatitis Day on July 28. Read Full Article.
EC Launches HIV/AIDS and Hepatitis B, C Prevention Campaign
Aug. 2 – The European Commission will finance an HIV/AIDS and Hepatitis B and C prevention campaign targeted to those 15-24 years old with 11 EU member states. Read Full Article.
Seattle: At-Risk Groups Urged To Get Tested for Hepatitis B
Aug. 2 – An estimated 10% of foreign-born Asian Americans suffer from chronic hepatitis B infection, a rate 20 times greater than the rest of the U.S. population. For those native to some Asian countries, such as Vietnam, Korea or China, rates are even higher. Read Full Article.
No End in Sight for Adult Hepatitis B Vaccine Shortage
Aug. 2 – The lengthy and ongoing shortage of adult hepatitis B vaccine has baffled some public health doctors, which began in January 2009 when Merck announced that equipment upgrades would disrupt production of the adult version of its hepatitis B vaccine. Read Full Article.
Taiwan Researchers Find Way to Predict Hepatitis B Virus Activity
July 26 – After analyzing HBV infections for the past 17 years, researchers found two intercellular mediators in the immune system that can “predict” activity of the hepatitis B virus which could help “customize” treatments for patients. Read Full Article.
Nicaragua to Use Hepatitis B Vaccine Donated by Cuba
July 26 – Cuba donated 140,000 doses of HBV that will be used to vaccinate Nicaraguan children as well as troops, policy officials and those in the Penitentiary System. Read Full Article.
Anesthesia Contamination Tied to Hepatitis
July 26 – U.S. researchers found patients can be infected with hepatitis B and hepatitis C via intravenous administration of anesthesia and that anesthesia contamination — not endoscopy contamination — was the cause of recent hepatitis outbreaks. Read Full Article.
HIV and HBV in Liver Cells May Contribute to Accelerated Liver Disease
July 19 – Interactions between HIV and HBV within liver cells appear to promote enhanced HIV replication and increased levels of HBsAg, though not HBV viral load, which may help explain worse liver disease progression observed in co-infected individuals. Read Full Article.
Risk Behaviors for Hepatitis B High, Vaccination Remains Low Among Adults
July 19 – About one-fifth of 18- to 44-year-olds in the U.S. have reported engaging in risky behaviors that indicate the need for the hepatitis B vaccine; however, more promotion is needed to boost vaccination rates among adults. Read Full Article.
56 kids get HIV, hepatitis after blood transfusion
July 19 – At least 56 children suffering from thalassaemia tested positive for HIV, hepatitis B and hepatitis C after receiving blood transfusion at government-run hospital in India. Over the past 18 months, 8 children were found to be HIV positive while 46 others were infected by HBV. Read Full Article.
Hep B Free Philadelphia Featured on CBS3
July 12 – HBF executive director Joan Block and former Philadelphia Health Commissioner Dr. Walter Tsou were interviewed on "Speak Up" of the CWPhilly show about the new HBV awareness campaign.
Better Than Sci Fi
July 12 – University of New Mexico researchers have developed a hand-held device that can detect HBV, HCV and other viral infections in blood, saliva and urine within 5 seconds. Read Full Article.
Twilight Effect: Talk About Unsafe Sex!
July 12 – Some teens are taking the vampire thing WAY too far. There have been recent reports of teens biting each other as a sign of love and passion… even drawing blood. Read Full Blog.
18,000 Veterans Exposed to Hepatitis and HIV
July 7 – The VA has urged nearly 2,000 veterans to return for blood tests because inadequately sterilized equipment may have exposed them to viral infections during dental procedures. Read Full Article.
Come and Dine with Hepatitis B Carrier
July 7 – A girl nicknamed Chucao invites people to have dinner with her on the streets of China to promote awareness that hepatitis B is not transmitted by having meals with infected persons. Read Full Article.
Clues to Preventing Return of Liver Cancer
July 7 – A small study finds antiviral therapy halts recurrence of liver cancer in patients with chronic hepatitis B, according to researcher Dr. Hie-Won Hann. Read Full Article.
Florida State's Solomon Alabi Tested Positive for Hepatitis B
June 28 – Former Florida State star center Solomon Alabi's precipitous fall in the recent NBA draft was due in part to a diagnosis of Hepatitis B. Read Full Article.
Screening Cancer Patients for Hepatitis B: Should it Be Routine?
June 28 – The American Society for Clinical Oncology concludes there is no need to screen all cancer patients prior to chemotherapy and immunosuppressive drugs, despite the risk of potentially fatal results due to reactivation of hepatitis B. Read Full Article.
Hepatitis: A Major Public Health Concern in Cameroon
June 28 – Some two million people in Cameroon suffer from hepatitis - 10% with HBV and 13% with HCV – with concerns that it is fast becoming a public health hazard, if not checked. Read Full Article.
Congressional Hearing on Viral Hepatitis Draws Attention to HR 3974
June 21 – A Congressional hearing on chronic viral hepatitis held on June 17 in Washington, DC calls for passage of HR 3974 to increase testing and treatment for hepatitis B and C. Read Full Article.
China FDA Approves Domestic Company to Manufacture Entecavir
June 21 – A leading company in China announced that they have obtained manufacturing approval for Entecavir from the China FDA with brand name "HeDing" and "HeEn". Read Full Article.
Exalenz BreathID System
June 21 – A feasibility study to test the effectiveness of a BreathID device to diagnose the severity of liver disease in people with HBV was conducted in Hong Kong with a 91% accuracy rate. Read Full Article.
Five People at Free W.VA Dental Clinic Developed Hepatitis B
June 14 – Three patients and two volunteers at a free dental clinic developed hepatitis B and hundreds of people who received treatment or volunteered there are encouraged to be tested. Read Full Article.
Cuba's Prevention Against Acute HBV Achieves Success
June 14 – Cuba reported only four cases of acute hepatitis B in 2009, due to the massive and systematic immunization campaigns promoted by the national health system. Read Full Article.
Do We Need to Determine Viral Genotype in Treating Chronic HBV?
June 14 – A recent paper concluded that determination of HBV genotype should form part of the management in treating chronic hepatitis B. Read Full Article.
Hepatitis B: Sex Hormone Explains Higher Liver Cancer Risk in Men
June 14 – Men with hepatitis B are more likely than women to develop liver cancer, and serum concentrations of male sex hormones may play a part, a new study suggests. Read Full Article.
Chronic Hepatitis B Covered by National Broadcasts
June 3 – An eight minute segment featuring the global and national significance of chronic hepatitis B infection will be televised on “PBS NewsHour” this evening and on June 4 a radio report will be broadcast as part of NPR's "Morning Edition." View PBS NewsHour and Listen to NPR Morning Edition.
NVHR Applauds World Health Organization Resolution on Viral Hepatitis
June 3 – A World Health Organization (WHO) resolution was approved to develop a comprehensive global approach to the prevention and control of chronic viral hepatitis as well as an historic WHO-sponsored World Hepatitis Day beginning next year on July 28, 2011. Read Full Article.
Government Battles Liver Cancer with Monitoring Program
June 3 – More than 1,000 people are participating in a government project aimed at fighting liver cancer with a reward system to encourage hospitals to enroll and routinely monitor high-risk patients. Read Full Article.
Researchers Fine-Tune Hepatitis B Trials
May 25 – Top clinicians and researchers from the U.S. and Canada met in Pittsburgh for three days to work on designs for two multisite treatment trials for hepatitis B, one for adults and one for children. Read Full Article.
Green Light for “While-You-Wait” Hepatitis B Test
May 25 – An inexpensive new test for the rapid detection of the hepatitis B virus has been given regulatory approval for use in the European Union, which will enable doctors to take immediate action from the test results. Read Full Article.
Sex Hormone Explains Higher Liver Cancer Risk in Men
May 25 – Male sex hormones may explain why men who suffer from the hepatitis B liver disease are more likely to develop liver cancer than women, researchers in Taiwan have found. Read Full Article.
World Hepatitis Day Rally Attracts
Almost 500 people traveled across the country for the first World Hepatitis Day rally held on May 19 at the U.S. Capitol in Washington, DC. The rally was organized by the National Viral Hepatitis Roundtable, in partnership with the Hepatitis B Foundation and other member organizations. Amidst multiple chants – 3—9—7—4 . . . Hepatitis no more! Hey, hey, ho, ho … Hepatitis go away! 1—2—3 … Liver cancer free! – speakers fired up audience. Three Members of Congress – Mike Honda, Charles Dent and Bill Cassidy – spoke, as well as patients who introduced themselves as “I am the face of hepatitis.” The bottom line .. we CANNOT be silent anymore! Too many Americans are dying from chronic hepatitis which is preventable and treatable. Learn more.
Presidential Message on World Hepatitis Day
May 19 – President Obama sent warm greetings to all those observing World Hepatitis Day and concluded with: “On World Hepatitis Day, we renew our support for people living with hepatitis and their loved ones, and for those who are working to improve treatment and prevention. I wish you all the best as you join together to take action against this terrible disease.” Read the Presidential Message on the White House blog. A copy of the Presidential Message is available here.
500 Million People Await WHO Assembly Decision on Viral Hepatitis
May 19 – Hundreds of patient groups await the World Health Organization's decision on a resolution that would provide global endorsement of World Hepatitis Day as the primary focus for national and international awareness-raising efforts. Read Full Article.
Dine with A Stranger with Hepatitis B?
May 19 – A girl with Hepatitis B took to the streets in China holding a sign saying "Will you have dinner with a HBV carrier" in a bid to raise awareness about the virus. Read Full Article.
Hepatitis Infections Behind U.S. Rise in Liver Cancer
May 10 – Liver cancer rates are increasing in contrast to most other major forms of cancer due to chronic hepatitis and more people need to be vaccinated, diagnosed and treated says a new CDC report. Read Full Article.
Some Patients with HBV Faring Better after Liver Transplant
May 10 – Treatment to reduce recurrence of hepatitis B appears to improve liver transplant outcomes, with approximately 50% drop in need for a second transplant according to a Mayo Clinic study. Read Full Article.
Women More Likely to Die while Awaiting Liver Transplants under the MELD System
May 10 – The MELD system, which prioritizes patients with end-stage liver disease for liver transplantation based on 3 laboratory measures, appears to favor men over women who are less likely to receive a donor liver. Read Full Article.
In Ads, Plea for Asians to Get Tests for Hepatitis
May 5 – In a new ad, 10 young Asian beauty queens are asked, "Which one deserves to die?" The new campaign sponsored by San Francisco Hep B Free intends to jar Asian Americans into taking action to combat the spread of hepatitis B. Read NYT Article and View Video.
Diabetes Is Leading Cause of Attributable Cases of Hepatocellular Carcinoma
May 5 – A new study sheds light on the risk factors for primary liver cancer (HCC) and found that although chronic HBV and HCV have the highest odds ratios for HCC, more cases of HCC overall are attributable to diabetes than any other risk factor. Read Full Article.
NanoBio Launches Program for Intranasal Vaccine for the Treatment of HBV
April 26 – NanoBio and the University of Michigan are funded by an NIH grant to work on a Phase I potential therapeutic intranasal vaccine for the treatment of HBV in patients. Read Full Article.
World Hepatitis Alliance Releases Report at EASL Meeting
April 26 – Research commissioned by World Health Organization finds 80% of governments regard hepatitis B and C as an urgent public health issue, according to the first major policy report on viral hepatitis from the World Hepatitis Alliance. Read Full Article.
500 Patients Warned of Possible Blood-Borne Virus Infection
April 26 – Nearly 500 people in Canada are being warned to get tested for hepatitis and HIV after contaminated medical gear used at Victoria General Hospital was linked to an elderly man's infection. Read Full Article.
IOM Report Says Primary Care Docs Lack Knowledge About Hepatitis B, Hepatitis C
April 12 – Many primary care health professionals are unaware of the high prevalence of HBV or HCV infection in some U.S. populations and often fail to identify infected so they can be managed appropriately. Read Full Article.
Traditional Chinese Medicine May Perform Better than Interferon or Lamivudine for Chronic HBV
April 12 – A joint U.S./Chinese review of clinical trials of traditional Chinese medicine formulations were found to work as well as or better than interferon and lamivudine for people with chronic HBV, according to Hepatology publication. Read Full Article.
Ailing Chinese Dissident Is Denied Early Release
April 12 – One of China's best-known dissidents has been denied early release from prison despite being seriously ill with HBV and possible liver cancer. Read Full Article.
More Hepatitis B Patients Sue State
April 2 – Six hepatitis B patients in western Japan filed a lawsuit, joining nearly 400 other people engaged in legal battles, for the government's failure to warn of the risk posed by shared needle use in group vaccinations. Read Full Article.
Curry Ingredient Shows Promise Against Liver Damage
April 2 – A compound found in the common curry spice turmeric appears to delay the liver damage that eventually causes cirrhosis. Read Full Article.
GSK Offers Free Vaccines to Uninsured Adults
April 2 – GlaxoSmithKline has launched the GSK Vaccines Access Program to provide its adult vaccines – including HBV - free of charge to help those over the age of 18 who lack insurance coverage for vaccines. Read Full Article.
New 5-Year Strategic Plan from CDC
March 5 – The 2010 plan describes the agency's overarching goals and strategies for preventing HIV/AIDS, viral hepatitis (A, B, and C), STDs, and TB over the next 5 years. Read Full Report.
Woman Needs Doctors Note To Attend Church
March 5 – Doctors notes may be needed to get out of school or work. But what about a doctor's note to get back into church? One woman needed such a note after being diagnosed with hepatitis. Read Full Article.
Changing the Face of Research and Science: A Nonprofit Biotech Incubator
Feb. 26 - Huffington Post featured an article about a unique nonprofit organization that created a biotech center to extend its research mission, which has expanded even in this tough economy. Read Full Article.
Inactive Hepatitis B Virus Can Still Cause Liver Cancer
Feb. 26 – Despite a belief by researchers that inactive carriers of hepatitis B virus (HBV) are not at high risk of disease progression, a new study suggests that such patients are still at increased risk of hepatocellular carcinoma (HCC) and liver-related death. Read Full Article.
Transplants That Do Their Job, Then Fade Away
Feb. 26 – Jonathan Nuñez was 8 months old when a liver transplant saved his life. Three years later, his body rejected the transplant, attacking it so fiercely that it wasted away and vanished. That result, seemingly a disaster, was exactly what his doctors had hoped for. Read Full Article.
Mouse With Human Liver May Lead to Cure for Hepatitis B and C
Feb. 26 – How do you study - and try to cure in the laboratory - an infection that only humans can get? A team led by Salk Institute researchers does it by generating a mouse with an almost completely human liver that is susceptible to human liver infections and responds to human drug treatments, providing a new way to test novel therapies. Read Full Article .
Age at Time of eAg Seroconversion Predicts Chronic HBV Prognosis
Feb. 19 – People who experience hepatitis B "e"" (HBeAg) seroconversion before age 30 have better long-term outcomes – including lower rates of cirrhosis and liver cancer - than those who seroconvert 10 years later. Read Full Article.
Zimbabwan Long Distance Runner Nhauro Dies
Feb. 19 – Crack former Zimbabwe long–distance runner Patrick Nhauro died at 52 years last week after battling hepatitis B for a long time. Read Full Article.
Estimation of Healthy Upper Limits for ALT in Asian Populations
Feb. 19 – The healthy ALT thresholds in biopsy-proven normal Asians were clearly lower than the previously accepted thresholds, as has also been noted in Europeans. Read Full Article.
Hepatitis: Are You At Risk?
Feb. 19 – Parade magazine covers hepatitis B and C which impacts 5 million Americans (1 in 60 people) as a result of the recent Institute of Medicine report on Hepatitis and Liver Cancer. Read Full Article.
Short Needle May Short HBV Protection for Obese
Feb. 12 – Obese adolescents and young adults may not generate an adequate immune response to the HBV vaccine because the needles used to vaccinate them are too short. Read Full Article.
14 Million Registered Hepatitis Patients in Pakistan
Feb. 12 - There are an estimated 14 million people suffering from the hepatitis epidemic in the country, of which 5.6 million are infected with HBV, says the Health Minister. Read Full Article.
Entecavir Improves Liver Function in Decompensated Chronic HBV
Feb. 12 – The antiviral drug entecavir (Baraclude) worked as well in chronic HBV patients with decompensated cirrhosis as it did in individuals with less severe liver damage, and over 1 year, it improved liver function in these patients with the most advanced disease. Read Full Article.
Dynavax Starts Hepatitis B Trial
Feb. 12 – Dynavax will start a 2,000-patient trial in Canada and the U.S. to show that Heplisav is just as good as Engerix-B (GlaxoSmithKline) eight weeks after the last active dose. Read Full Article.
NVHR: Stop Liver Cancer 'Dead in Its Tracks' By Closing Funding Gap for Viral Hepatitis
Feb. 5 – “If policymakers are serious about reducing US cancer rates, including liver cancer, they should act immediately … to fully fund viral hepatitis education, screening, and surveillance programs for five million Americans,” says NVHR Chairperson. Read Full Article.
Going To Help In Haiti? Don't Forget Shots
Feb. 5 – Relief workers and others traveling to Haiti are being advised to get vaccinated against several potentially life-threatening illnesses, including HBV which is endemic in the country. Read Full Article.
Perinatal HBV Transmission May Occur Despite Newborn Vaccination and Immune Globulin
Feb. 5 – Babies born to mothers with HBV infection may become chronically infected even if they receive the HBV vaccine and hepatitis B immune globulin (HBIG), according to a Dutch study. Read Full Article.
We Honor the Groundhog One Day Each Year
Feb. 1 – Why would a hairy little critter be so honored as to have a special day? And why is it so valuable for studying liver disease in humans, particularly hepatitis B and liver cancer? Read Full Article.
Bill, Melinda Gates Pledge $10 Billion for Vaccines
Feb. 1 – The Bill and Melinda Gates Foundation will commit $10 billion over the next decade to vaccinate 90 percent of children in developing nations (including HBV), and to help develop vaccines for the world's poorest countries. Read Full Article.
Government Urged to Subsidize Anti-Hepatitis B Drugs
Feb. 1 – Adding anti-hepatitis B drugs to Beijing's medicine insurance list would solve severe health concerns, says a senior medical expert, and “the government has a responsibility to pay for treatment...before the financial burden becomes much heavier.” Read Full Article.
NVHR: Don't Leave 5 Million Americans with Chronic Hepatitis Out in the Cold with Budget Freeze
Feb. 1 – NVHR issues a challenge to the White House and Congress: “It is critical that policymakers understand that a budgetary freeze would leave more than 5 million Americans afflicted with chronic viral hepatitis out in the cold … and it's time to address these diseases with the full force of decisive federal action that they deserve.” Read Full Article.
More Couples Calling Off Marriage After Tests
Jan. 25 -Iin 2009, three cases of HIV/AIDS, 76 cases of HCV, and 308 HBV were discovered in premarital testing, and the higher rate of couples calling off marriages following positive test results was due to Advisory Clinics persuading them to cancel their plans. Read Full Article.
10% of Executives at High Risk of Serious Liver Disease Due to HBV
Jan. 25 - One out of every 10 executives of medium-sized and large companies in Taiwan have chronic HBV but have taken no steps to treat the condition, leaving them vulnerable to serious liver disease, according to the results of a survey. Read Full Article.
Reduced Response to HBV Vaccine in Celiac Disease Patients
Jan. 25 - Celiac disease patients do not produce adequate protective antibody levels after receiving the HBV vaccine, which may represent a significant public health problem that needs to be addressed. Read Full Article.
Are You Safe In Your Salon?
Jan. 18 - Just because your salon boasts of a swanky ambience and high-priced services, it doesn’t mean you are safe since viral infections including HIV, hepatitis B and C, etc. are things to watch out for. Read Full Article.
Landmark IOM Report on Hepatitis & Liver Cancer Finds Inadequate Federal Funding Thwarting Education, Surveillance Efforts
Jan. 18 – The National Viral Hepatitis Roundtable (NVHR), a coalition of more than 150 groups, renews its call for the U.S. to take immediate and decisive action to implement the report’s key recommendations since about 1 in 50 Americans are affected. Read Full Article.
Notes from JPMorgan: Gilead's [HBV] Combos
Jan. 18 - Keep an eye on Gilead's partnership in Asia with GlaxoSmithKline for marketing rights for tenofovir (Viread) to treat HBV in China, and possible talks about a fixed-dose combination in Asia, which would be a first for HBV treatment. Read Full Article.
Neither Diabetes nor Overweight Is a Risk Factor for Hepatocellular Carcinoma
Jan. 18 - On the basis of the community-based studies, neither diabetes nor being overweight was a risk factor for liver cancer in a dual HBV and HCV endemic area. Read Full Article.
IOM Report on Hepatitis and Liver Cancer Released
Jan. 11 – The Institute of Medicine (IOM) has released its report on the current approach to the prevention and control of hepatitis B and C in the U.S., and concludes that it is not working. With more than 5 million Americans suffering from these chronic diseases, more needs to be done to improve federal and state resources. Read Full Article.
Hep B Activists Named 2009 Top Ten Legal Figures in China
Jan. 11 – Civil right activist Lu Jun, director of the Beijing Yirenping Center, a nonprofit organization dedicated to fighting anti-HBV discrimination, was named one of the Top 10 Legal Figures in China by state-administered legal websites in December 2009. Read Full Article.
Increased Caffeine Consumption is Associated with Reduced Hepatic Fibrosis
Jan. 4 – An NIH study demonstrated that caffeine consumption, particularly from regular coffee, above 2 cup equivalents per day, was associated with less severe fibrosis. Read Full Article.
High Risk of Hepatitis for Hospital Scavengers
Jan. 4 - Sanitary workers and scavengers (particularly children collecting garbage) of hospitals and clinics are at a high risk of getting infected with viruses like hepatitis B, C and HIV because of their pilferage of hospital waste. Read Full Article.
Villanova Yarou Cleared to Practice
Jan. 4 - Villanova freshman center Mouphtaou Yarou was cleared to resume practice with the Wildcats after missing 10 games since being diagnosed with hepatitis B on Dec. 1. Read Full Article.
Number of Tattoo-Parlor Permits Rises
Jan. 4 - Tattoo shops appear to be recession-proof- more people are getting skin ink, and more places are opening. However, zoning restrictions are not enough to guarantee safety and cleanliness. It's a big concern,” says one owner. “They are hepatitis factories." Read Full Article.
China Drops Hepatitis B Testing for School, Employment Amid Efforts to Fight Discrimination
Dec. 29 – The Health Ministry announced that China will soon stop mandatory hepatitis B tests for people applying for jobs or admission to schools after years of efforts by civic groups to fight discrimination against carriers of the liver disease. Read Full Article.
Over 4 Million Suspected HBV Carriers in Pakistan
Dec. 28 – Experts speaking at a public education event report that about 4 to 5 million people are suspected HBV carriers in Pakistan. Read Full Article.
Positive Response to Premarital Test
Dec. 28 - An awareness campaign on pre-marital health screening to prevent the spread of hereditary, genetic and communicable diseases (such as HBV) conducted in shopping malls has received a positive response from the public. Read Full Article.
Milk Thistle May Limit Liver Damage from Chemo
Dec. 21 - An herb used since ancient times to treat liver ailments may help reduce the liver damage caused by some cancer drugs, suggests a recent study. Read Full Article.
Citywide Campaign Becomes National Hep B Model
Dec. 21 - National recognition, high-profile partnerships, in-kind donations and non-stop media buzz have the grassroots “Hep B Free San Francisco” campaign receiving kudos as a community in action from the federal government. Read Full Article.
Chronic HBV and Rubella Susceptibility in Pregnant Women
Dec. 21 – The first study to demonstrate an association between chronic HBV infection with rubella susceptibility in subjects from the Asian-Pacific region where chronic HBV is endemic was recently published. Read Full Article.
Scientists Uncover Protective Mechanism Against Liver Cancer
Dec. 21 – A team of scientists have identified a protein switch – TAK1 - that helps prevent liver damage (e.g. inflammation, fibrosis) that could lead to new insights into the development of liver disease and cancer. Read Full Article.
Students Face January 4th Immunization Deadline
Dec. 14 – Students in Kansas will be excluded from school after January 4 if they are not in compliance with the required immunizations, which now include three doses of the HBV vaccine for 6th to 9th grade students. Read Full Article.
New Phase I/IIa Study of Recombinant Human Interleukin-7 (CYT107) for Treatment of Chronic HBV
Dec. 14 - Cytheris announced it has begun enrolling patients in its Phase I/IIa study of an investigative immune-modulator, recombinant human Interleukin-7 (CYT107), in combination with standard antiviral treatment and vaccination in HBeAg-negative chronic HBV patients. Read Full Article.
INDIA: Most Newborns Do Not Get Vaccinated Against Hepatitis B
Dec. 14 - Shortage of vaccine and lack of awareness about the significance of HBV vaccination are the key reasons why very few newborns are being immunised in country. Read Full Article.
NVHR Offers Congressman Hank Johnson Support as He Battles Chronic HCV
Dec. 8 - Congressman Hank Johnson (D-Ga.) announced that he is undergoing treatment for chronic HCV and is believed to be the first sitting Member of Congress to acknowledge he is chronically infected with HCV. Read Congressman Johnson’s Announcement. Read NVHR News Release.
Hepatitis Redress Legislation Passed in Japan
Dec. 7 - A comprehensive bill was cleared in Japan to promote research and provide financial support to those infected with HBV and/or HCV effective Jan. 1, 2010. Read Full Article.
Statin and Diabetes Drug Show Activity against HBV in Laboratory
Dec. 7 - Simvastatin (Zocor), a medication used to lower blood cholesterol, had a synergistic effect against HBV when combined with antiviral drugs in a laboratory study. Read Full Article.
Peru Tribe Threatened by Hepatitis B
Dec. 7 - A health emergency has been declared in the Peruvian Candoshi tribe whose existence is threatened by a hepatitis B outbreak that began almost two decades ago, with members dying because they have not received treatment. Read Full Article.
Villanova Yarou Out Indefinitely with Hepatitis B
Dec. 2 - Villanova announced yesterday that 6-10 freshman foward-center Mouphtaou Yarou, who had missed the last four games, has tested positive for Hepatitis B and will remain out indefinitely. Read Full Article.
Gilead and GSK Announce Agreement to Commercialize Viread in Asia
Nov. 30 - Gilead and GlaxoSmithKline announced a licensing agreement to commercialize Viread (tenofovir) for chronic HBV infection in adults in five countries in Asia. Read Full Article.
Antifibrotic Effects of Green Tea
Nov. 30 - Green tea may protect liver cells and reduce the deposition of collagen fibers in the liver; thereby, could be a safe and effective strategy for improving hepatic fibrosis. Read Full Article.
Assessing Best Practices in HBV Therapy
Nov. 30 – A comprehensive overview of best practices in the treatment of chronic HBV that includes strategies for antiviral resistance and co-infections is available from AASLD 2009 (CME and CEU available). Read Full Article. Read Full Article.
Research May Show Why Hepatitis B Infection is Worse in Men than Women
Nov. 23 - Chinese scientists are reporting that the discovery of unusual liver proteins, found only in males, may cause HBV infection to be more severe in men than women. Read Full Article.
Dynavax Completes Enrollment of First Cohort of Patients in Phase 1b Clinical Trial for HBV Therapy
Nov. 23 - Enrollment has been completed for the first of three cohorts of patients that will receive DV-601 HBV therapy in Europe. Read Full Article.
Hepatitis Journal Options: CME-Certified Collection Available Online
Nov. 23 - Comprehensive Capsule Summaries of the most relevant hepatitis journal articles with exclusive commentaries authored by leading experts and downloadable PowerPoint slidesets now available online. Read Full Article.
National Policy on Hepatitis B to be Launched Next Year
Nov. 23 – The Health parliamentary secretary in Malta released a document aimed to launch a national policy on hepatitis B to be implemented next year. Read Full Article.
Hematologist Suspended (in HBV Reactivation Case)
Nov. 16 – A doctor has been suspended from practice for failing to test a lymphoma patient for HBV before starting treatment; the patient died from hepatitis B reactivation. Read Full Article.
Liver Reserve Measured in Breath Test
Nov. 16 - A simple breath test gives a good overall measure of liver function in patients with chronic viral hepatitis and could help in evaluating potential liver transplant candidates, a researcher said here. Read Full Article.
Silent Epidemic of Viral Hepatitis May Lead to Boom in Serious Liver Disease
Nov. 16 – JAMA article highlights that although prevention efforts have helped dramatically reduce the incidence of hepatitis B and C infections in the U.S., severe progressive liver disease such as cirrhosis and liver cancer are on the rise. Read Full Article.
High Viral Load and HBeAg Positive are Associated with Decreased Life Expectancy
Nov. 16 - Individuals with chronic HBV have a shorter life expectancy than uninfected people, according to a mathematical model presented at the recent AASLD Meeting in Boston. Read Full Article.
Viral Hepatitis and Liver Cancer Legislation Introduced in Congress Today
Nov. 2 – A bipartisan bill (H.R.3974) – Viral Hepatitis and Liver Cancer Control and Prevention Act 2009 – was introduced today in Congress today by U.S. Representatives Mike Honda (D-CA) and Charles Dent (R-PA) to address the needs of more than 5 million Americans suffering from chronic viral hepatitis. This is the first legislation that addresses both HBV and HCV, and represents a huge advocacy victory. Read Full Article.
A Call to Action! We Need Your Help Now!
We need your help to pass the historic “Viral Hepatitis and Liver Cancer Prevention and Control Act of 2009 (H.R.3974). Contact YOUR U.S. REPRESENTATIVE today to support this bill!!
Make a phone call to 1-202-224-3121 or send an email from http://writerep.house.gov.
If you don’t know who your U.S. Representative is, go to www.congress.org and enter your zip code in the upper right corner.
Use your social and professional networks to get more people like you to call their representatives! Forward this Call to Action widely!
Chronic Hepatitis B Infection Could Rise In Australia
Oct. 26 - According to a recent report, chronic HBV infections could rise in Australia with a potential three-fold increase in the number of people living with liver cancer directly caused by hepatitis B. Read Full Article.
30% of China's HBV Patients Can't Afford Long-Term Treatment
Oct. 26 - Nearly 30% of HBV patients in China do not stick to long-term medical treatment or take medicine less frequently than they should due to lack of money and 42 % of the respondents do not visit doctors regularly. Read Full Article.
Executive Summary Now Available from National Expert Policy Forum on HBV and HCV
Oct. 26 - A diverse group of experts and community members convened in September to discuss a national response to chronic viral hepatitis in the U.S. through improved prevention, detection, and patient care, which was titled “The Dawn of a New Era: Transforming our Domestic Response to Hepatitis B & C.” Read Full Report.
Remarks about HBV by President Obama at AAPI Initiative Executive Order Signing Event
Oct. 19 - President Obama signed an Executive Order re-establishing a President's Advisory Commission and White House Initiative on Asian American and Pacific Islanders (AAPI) to focus on the needs and concerns of these communities, with hepatitis B specifically named as an important health disparity. Read Full Article.
Botox Lawsuit Raises Issues on Injections
Oct. 19 - A federal lawsuit filed in California raises alarm that the Botox business model "create[s] an unacceptable and unreasonable risk of serious and debilitating injuries and illnesses, including HIV and Hepatitis B” due to single-use medication vials used on more than one patient. Read Full Article.
Subaru Donates “Hep B Hero Mobile”
Oct. 19 - Subaru of America is joining the San Francisco Hep B Free campaign as the official vehicle and partner by donating the use of a 2010 Subaru Legacy detailed with full color artwork to encourage everyone to “B a Hero” in preventing liver cancer and the hepatitis B disease. Read Full Article.
HBV Genotypes E, F, G, and H Appear Responsive to Treatment with Interferon Alpha
Oct. 19 - Patients with hepatitis B genotypes E, F, G, and H appear to be sensitive to interferon alpha, as well as nucleoside/nucleotide analogs, although sustained virological response rates did not exceed 50%. Read Full Article.
More Than 1,800 Florida Patients May Have Been Exposed To Hepatitis and HIV
Oct. 12 - Broward General Medical Center in Florida said a nurse reused saline bags and tubing during cardiac stress tests and has sent letters to all 1,851 people who may have been affected from January 2004 to early September 2009 to be tested for Hepatitis and HIV. Read Full Article.
Could Hepatitis B Vaccine Be Harmful?
Oct. 12 - In a newly-published study, vaccinated monkeys demonstrated “significant delays in the development of critical survival reflexes" compared to an unvaccinated control group. Read Full Article.
Short Strand of RNA May Help Predict Survival and Response to Treatment for Liver Cancer
Oct. 12 - A small RNA molecule, known as a microRNA, may help physicians identify liver cancer patients who, in spite of their poor prognosis, could respond well to treatment with a biological agent called interferon. Read Full Article.
Liver Cells Grown From Patients' Skin Cells…Treatment of Liver Diseases Possible
Oct. 12 - Scientists have successfully produced liver cells from patients' skin cells which is “a crucial step forward towards developing therapies that can potentially replace the need for scarce liver transplants," says lead researcher. Read Full Article.
Expert Panel of Pediatric Liver Specialists Publishes Recommendations for Monitoring and Referral of Children with Chronic Hepatitis B Infections
Oct. 5 – An expert panel of nationally recognized pediatric liver specialists convened by the Hepatitis B Foundation published the first recommendations for children chronically infected with HBV that urge consistent monitoring and referral, which was posted as an early publication today in the premier medical journal “Pediatrics”. Read Full News Release.
National Awareness Campaign “B HERE” Targets Hepatitis B
Oct. 5 – Gilead Sciences has launched a new online social media campaign to raise awareness about hepatitis B and its impact on the Asian American community through a highly interactive website that invites everyone to “Make Your Mark on Hepatitis B”. To spread the word, visit www.willyoubhere.com.
Bone Problems among Women, But Not Men, with HIV and Hepatitis
Oct. 5 - HIV-positive women who are also infected with HBV or HCV have lower bone density than positive women not infected with HBV or HCV. Among men in the study, however, no connection between HIV, viral hepatitis and bone mineral loss was documented. Read Full Article.
Occult Hepatitis B Infection and Its Possible Impact on Chronic HCV Infection
Oct. 5 - Evidence of the probable impact of occult HBV in patients with chronic HCV infection suggests a possible correlation with lower response to anti-viral treatment, higher grades of liver histological changes, and also developing hepatocellular carcinoma. Read Full Article.
Acute Hepatitis B and C Infection among Men Who Have Sex with Men
Sept. 25 - In the U.S., the incidence of acute HBV and HCV infection in 2007 were the lowest ever recorded. But trends have not been so favorable for gay and bisexual men. Read Full Article.
Patients with Cirrhosis and Impaired Cognitive Abilities Have More Motor Vehicle Accidents
Sept. 25 - A recent study found that patients with cirrhosis of the liver who developed minimal hepatic encephalopathy (MHE) had a significantly higher crash rate than the annual crash rate. Read Full Article.
Hepatitis B Vaccine Fails in Half of All Celiac Patients
Sept. 25 - A timely article on failure of the HBV vaccine in people with celiac disease asks the sensible question of whether it is time to reevaluate our current vaccine procedures. Read Full Article.
AASLD Issues Updated Practice Guidelines for Management of Chronic Hepatitis B
Sept. 22 – The updated AASLD 2009 Practice Guidelines for HBV include key changes in recommendations for 1st and 2nd line antiviral therapy based on new research and the recent approval of tenofovir (Viread) for hepatitis B. Read Full Article.
Hepatitis B Vaccinations at Birth Are Tied to Less Liver Cancer
Sept. 22 - Vaccinating children against HBV at birth can significantly reduce liver cancer in older children, a new study in Taiwan has found. Read Full Article.
Hepatitis Myths Put Canadians at Risk
Sept. 21 - According to survey results, the majority of Canadians believe common myths that hepatitis A and B are mostly diseases contracted outside Canadian borders. Read Full Article.
Animals Predisposed to Liver Cancer Can Avoid It with Low-Fat Diet
Sept. 21 - The connection between obesity and cancer is not well understood, but researchers comparing two strains of mice (one more susceptible to cancer) report provocative new findings. Read Full Article.
Pennsylvania Approves Over-the-Counter Syringe Sales
Sept. 21 - PA Department of State acts to increase access to clean needles and help slow the spread of blood-borne diseases including HIV, AIDS and hepatitis. Read Full Article.
New Jersey: 29 Hepatitis B Cases Tied to Doctor's Office
Sept. 14 - In March, the state said 5 of Dr. Parvez Dara's patients were found to have hepatitis B and that nearly 2,800 patients should get tested for it. There are now 29 positive cases, according to the state Health Department. Read Full Article.
FDA Requires Updated Labeling for Interferon Alpha Products Due to Safety Issues
Sept. 11 - Several serious events have been identified in recent months related to reported experiences with alpha interferon products and labeling has been updated to incorporate each of these class safety issues. Read Full Article.
Chinese Hepatitis B Carrier Gets Access to Food & Beverage Industry
Sept. 11 - Lei Chuang is said to be the first lucky person with hepatitis B to get a health certificate, a pass that allows him to work in the food industry, since the implementation of the Food Safety Law of the People's Republic of China which lifts the ban on HBV carriers. Read Full Article.
HBV Treatment Controversies in 2009: A Debate
Sept. 11 - Maximizing Success While Preserving Future Options: Debating Antiviral Treatment Options is a Johns Hopkins online CME course of interest to patients and providers. Read Full Article.
Gene Variant Heightens Risk of Severe Liver Disease in Cystic Fibrosis
Sept. 11 - Researchers have discovered a genetic risk factor for severe liver disease in people with cystic fibrosis...that could play a role in how rapidly persons with viral hepatitis develop liver complications. Read Full Article.
National Summit on Viral Hepatitis to be Held Sept. 10-11 in Washington, D.C.
Sept. 3 - Politicians, medical experts and community advocates will gather for 2-day conference to develop action plan to combat hepatitis B and C in the U.S. Read Full Article.
Race Not a Factor in Liver Transplantation
Sept. 3 - Racial disparities exist in many areas of health care…but race may not play a role in survival after liver transplants for hepatitis B infection, nor while waiting for one, according to a new study. Read Full Article.
Police Arrest 6 for Supplying Blood Tainted with Hepatitis B and C
Sept. 3 - Police charged six people, including a doctor, for spreading infectious diseases after they allegedly supplied blood contaminated with hepatitis B and C to blood banks in northern India. Read Full Article.
Should Baraclude and Tenofovir be First-line Treatment for Chronic HBV?
Aug. 28 - At the annual Digestive Disease Week 2009 meeting this week in Chicago, a panel of experts discussed the prevention and management of antiviral drug resistance in patients receiving long-term treatment for chronic HBV infection. Read Full Article.
FDA Investigates Reports of Liver Damage from Weight Loss Drugs
Aug. 28 - The U.S. FDA is reviewing data on suspected cases of liver injury with orlistat (Xenical or Alli), but are not yet advising any changes in the use of these weight loss drugs. Read Full Article.
Hepatitis B Vaccination Failure in Celiac Disease
Aug. 28 - A recent study confirms that celiac patients, particularly young children, have a lower percentage of response to hepatitis B vaccination than healthy subjects. Read Full Article.
Hepatitis B - How Much of a Risk to Travelers?
Aug. 21 - Hepatitis B is one of the most prevalent viruses across the globe yet it is often given a low profile by many travel health advisers. Read Full Article.
Myopathy and Neuropathy Associated with Oral Therapies for HBV
Aug. 21 - The development of clevudine as a treatment for hepatitis B was terminated recently because of case reports of myopathy. Read Full Article.
Sustained Response in HBeAg Negative Chronic HBV Patients after Pegasys
Aug. 21 – Researchers randomly assigned more than 500 HBeAg negative HBV patients to receive therapy with Pagasys or lamivudine or combination of both for 48 weeks. Read Full Article.
Patient Sues New Jersey Doc in Hepatitis B Outbreak Case
Aug.18 - A New Jersey oncologist whom health official’s suspect was responsible for a hepatitis B outbreak earlier this year has been sued by one of his patients. Read Full Article.
Hepatitis Cased Linked to South Dakota Clinic
Aug.18 - Siouxland Urology Center in South Dakota appears to be the culprit in exposing 6,000 patients to HIV and hepatitis, some of whom have tested positive for blood borne illnesses. . Read Full Article.
Community-Based Hepatitis B Screening Programs in the U.S. in 2008
Aug.18 - Currently, most hepatitis B screening in the United States is performed by independent community organizations and information about the location, number and ethnicity of people screened, and the prevalence among those screened was collected. Read Full Article.
Novel Genotype J Assigned to Genetic Variant of HBV
Aug. 8 - A genetic variant of HBV divergent from known human and ape genotypes - assigned as novel genotype J - was isolated from an 88 year old Japanese patient with hepatocellular carcinoma and may help to trace the origin of HBV. Read Full Article.
Grapefruit Juice. The Good News
Aug. 8 - Grapefruit juice has been found to give cancer treatment a boost. Doctors say chemicals in juice prevent enzyme from breaking down certain drugs, boosting their effects. Read Full Article.
Wistar Scientists Find Key to Strengthening Immune Response to Chronic Infection
Aug. 8 – Researchers have identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, HCV and HBV, as well as some cancers, such as melanoma. Read Full Article.
Hepatitis Group Is Harassed in China
July 31 - Chinese authorities seized dozens of newsletters from a nonprofit group that fights discrimination against people with hepatitis B they claimed had been printed without official permission. Read Full Article.
Helpful Guidelines for Managing Hepatitis B
July 31 - New guidelines from the NIH address the current burden of hepatitis B, the benefits and risks of treatments and the need to monitor patients are summarized for easy use. Read Full Article.
U.S. Adults Dying of Preventable Diseases
July 31 - Vaccine-preventable diseases kill more adult Americans each year than car wrecks, breast cancer, or AIDS. Yet relatively few in the U.S. know much about these diseases -- and far too few adults get vaccinated. Read Full Article.
Members of Congress Speak Out on Hepatitis B and C
July 24 - Congressmen Mike Honda (CA), Charlie Dent (PA), Anh “Joseph” Cao (LA), David Wu (OR), Bill Cassidy (LA) and Donna Edwards (D-MD) gathered with more than 70 other people on Capitol Hill to get tested and raise awareness that chronic HBV and HCV impact almost 6 million Americans. Read Full Article.
Study Reports Sperm Function Impaired by Hepatitis B Virus
July 24 – A study reports that the hepatitis B virus envelope protein S (HBs) has a direct detrimental effect on sperm function. Read Full Article.
China's Pharmaceutical Market Primed to Explode
July 24 - China's ambitious $124 billion effort to provide basic health coverage by 2011 is a brimming opportunity for companies making drugs for diseases, such as hepatitis B, that will have blockbuster potential. Large pharmaceutical companies have geared up their outreach efforts to increase treatment rate for the liver disease that kills more than 300,000 Chinese a year. Read Full Article.
Focusing HIV Treatment Helps Control HBV Co-Infection
July 20 - Prolonged use of highly active antiretroviral therapy (HAART) to treat people infected with both HIV HBV helps to better control the hepatitis B infection and could delay or prevent liver complications. Read Full Article.
Hepatitis B Vaccine Supply Issues for Infants, Children, and Adults
July 20 - Since February, there have been intermittent pediatric hepatitis B vaccine supply shortages in the U.S. The CDC has published a useful Q&A of the important issues. Read Full Article.
Dietary Influences of Liver Disease Examined
July 20 - Diets high in protein and cholesterol are associated with a higher risk of hospitalization or death due to cirrhosis or liver cancer, while diets high in carbohydrates are associated with a lower risk. Read Full Article.
Reasons Not to Panic over a Painkiller
July 10 - Last week, a federal advisory committee raised concerns about liver damage with overuse of acetaminophen, and the news left many consumers confused and alarmed. Read Full Article.
17 Year Old "It Girl" Breaks Taboos on Hepatitis C
July 10 - Gorgeous, wealthy Jazzy de Lisser is one of London’s “It” girls with HCV and her best friend is Sting’s daughter. To raise awareness and change people’s perceptions, she released an award-winning film about her life and the debilitating treatment she went through. Read Full Article.
VA Sends Letter about Unclean Equipment
July 10 - A Department of Veterans Affairs letter pledges free medical care and treatment for former patients who have tested positive for HIV or hepatitis since being exposed to endoscopic cleaning mistakes at three VA hospitals in the Southeast. Read Full Article.
Dentistry Link in Hepatitis B
July 10 – An average of nearly 300 people in Beijing were infected with hepatitis B every day via dental treatments, an industry insider estimates. Read Full Article. Read Full Article.
FDA Takes Action on Acetaminophen
July 6 - Acetaminophen is generally safe for most people when used as directed, but it can cause life-threatening liver injury if taken at high doses or by individuals at risk for hepatotoxicity (i.e. chronic hepatitis). Read Full Article.
FDA Advisory Panel Urges Black Box Warning and Potential Ban on Prescription Acetaminophen Combinations Due to Liver Toxicity
July 6 - The U.S. FDA held hearings on acetaminophen liver toxicity - a leading cause of acute liver failure, accounting for an estimated 50,000 emergency room visits and nearly 500 deaths annually in the U.S. Read Full Article.
Hepatitis B Virus Mutations May Predict Risk of Liver Cancer
July 6 - Certain mutations in the DNA of the hepatitis B virus are associated with the development of liver cancer and may help predict which patients are at increased risk. Read Full Article
Ignorance Fueling Spread of Hepatitis B in Asia
July 6 - Ignorance is fueling the spread of hepatitis B in Asia, where patients are failing to get proper treatment and not enough is done to reduce transmission of the virus from mother to child, an expert said. Read Full Article.
VA Facilities Improperly Sterilized Colonoscopy Equipment
June 26 - Fewer than half of VA facilities selected for random inspections had properly sterilized colonoscopy equipment with hospitals in Florida, Georgia and Tennessee possibly exposing 10,320 veterans to HBV, HCV or HIV. Read Full Article.
FDA to Hold Advisory Meeting on Liver Injury and Acetaminophen
June 26 - The U.S. FDA will hold an advisory meeting on June 29-30 in Maryland to address the problem of liver injury related to the use of acetaminophen in both over-the-counter (OTC) and prescription products. Read Full Article.
Guide to Hepatitis B for People Living With HIV Now Available
June 26 - Treatment Action Group has just released a guide in both English and Spanish that provides information on the prevention, care, and treatment of HBV, and the impact of HBV on HIV disease. Read Full Article.
Patient to Patient Transmission of HBV: A Systematic Review of Outbreaks
June 26 - HBV outbreaks are still a serious public health concern in high-income countries, so to identify the most frequent infection pathways and clinical settings a systematic review between 1992 and 2007 was conducted in the U.S. and EU. Read Full Article.
Effect of Coffee and Green Tea Consumption on the Risk of Liver Cancer
June 19 – A new study suggests that coffee consumption may reduce the risk of liver cancer regardless of HBV and HCV infection status, whereas green tea may not reduce this risk. Read Full Article.
Risk of Liver Cancer in Women with HBV Varies with Number of Pregnancies
June 19 - Risk for primary liver cancer was significantly higher among women with HBV than among women without the virus, according to a new study. Read Full Article.
VA Blasted at Hearing on Contamination Scandal
June 19 - At yesterday’s hearing before a House Veterans Affairs committee, the VA was roundly criticized for not increasing safeguards and improving procedures after shoddy colonoscopies and endoscopies were potentially linked to the spread of HIV, HBV and HCV. Read Full Article.
Kids With Hepatitis Go Without Treatment
June 12 –Many Australian children with hepatitis B or C are going without the medicines they need because of a "head in the sand" approach by health authorities, new research has found. Read Full Article.
Okyeame Kwame Fights hepatitis B
June 12 – Award-winning “Rap Doctor” Kwame in Ghana has organized free HBV screenings to help save lives, “especially those of young people, who are the backbone of the country’s future.” Read Full Article.
Breath Test Could Help Assess Liver Function
June 12 – A simple, quick breath test may help predict prognosis in patients with chronic liver disease, a researcher reported at DDW last month. Read Full Article.
Physician Practices Regarding Adult Hepatitis B Vaccination: A National Survey
June 12 - Less than 50% of adults with risk factors for hepatitis B infection have been vaccinated. In a national survey, less than one third of primary care physicians reported routinely assessing for and vaccinating adults with hepatitis B risk factors. Read Full Article.
CalHEP Plans Education and ACTION on June 10
June 8 – Please join the California Hepatitis Alliance - CalHEP – which is organizing a rally and legislative visits in Sacramento on June 10 for HBV and HCV. Read Full Article.
Physician Practices Regarding Adult Hepatitis B Vaccination: A National Survey
June 8 - Less than one-third of primary care physicians reported routinely assessing for and vaccinating Adults with hepatitis B risk factors. Read Full Article.
Hepatitis B May Increase All-Cause Mortality in HIV-Positive People
June 8 – First meta-analysis finds that HIV co-infections with HBV result in a significantly higher rate of all cause mortality than without HBV. Therefore, HBV should be aggressively treated in HIV co-infected persons. Read Full Article.
Vegas Hepatitis C Outbreak Spurs New Laws
June 8 - Spurred by a hepatitis C outbreak in Las Vegas that led to the largest patient notification in U.S. history, new laws have been introduced to lessen the chance for a similar problem in the future. Read Full Article.
Miss Ghana Marks World Hepatitis B Day
June 1 - Miss Ghana 2008 called on Government to include vaccination against Hepatitis B in the National Health Insurance Scheme to ensure that Ghanaians get tested and vaccinated. "People who are tested positive can be treated in Ghana," she said. Read Full Article.
Heavyweights, Hepatitis and Lawsuits
June 1 – The World Boxing Association fight scheduled on May 30 between heavyweight champ Valuev and Chagaev was cancelled due to a hepatitis B infection found in Chagaev's blood. Read Full Article.
Does HBV Viral Load Level Predict Development of Liver Fibrosis?
June 1 - Two studies presented at EASL found that the role of HBV viral load differs for HBeAg-negative and HBeAg-positive individuals in the development of fibrosis. Read Full Article.
National Viral Hepatitis Roundtable Observes World Hepatitis Day and Calls for Increased Federal Action
May 21 – NVHR calls for greater investment in public health and federal leadership to improve the care and support of the almost 6 million Americans suffering from chronic hepatitis B and C. Read Full Article.
Advocacy Groups Deplore Cuts to WHO Agenda
May 21 - H1N1 flu was allowed to knock viral hepatitis from the agenda of this week's World Health Organization congress. “One million people will die before the WHO Assembly next meets in 2010,” said Charles Gore, president of the World Hepatitis Alliance. Read Full Article.
Cuba, A Nation without Hepatitis B
May 21 - Systematic immunization campaigns carried out in Cuba over the past 17 years have allowed the nation to reduce the incidence of acute hepatitis B more than 99%. Read Full Article.
In Midst of Pediatric Hepatitis B Vaccine Shortage, CDC Urges Docs Not to Hoard Doses
May 21- Supplies of pediatric hepatitis B vaccines are expected to remain tight through the summer, but CDC says that supplies will be sufficient through the end of the year, if providers order wisely. Read Full Article.
World Hepatitis Day Message from President Obama
May 19 – "I extend my warmest greetings to all those recognizing World Hepatitis Day. Your commitment to public health is evident in your ongoing work to raise awareness and take action against this life-threatening illness." Read Full Message
Am I Number 12?
May 19 – Is the second annual World Hepatitis Day as part of an ongoing movement to raise awareness of the global problem of chronic hepatitis B and hepatitis C which afflicts nearly
1 out of 12 people worldwide. Read Full Article
Congressional Briefing on Chronic Viral Hepatitis and Liver Cancer
May 19 – In recognition of World Hepatitis Day and May as National Hepatitis Awareness Month, the Hepatitis B Foundation is hosting a Congressional briefing titled "Chronic Viral Hepatitis: A Liver Cancer Story" with special guests Congressmen Mike Honda and Charlie Dent. Read Press Release
CDC Recognizes National Hepatitis Awareness Month and World Hepatitis Day
May 19 – Both events draw attention to the large but often under-recognized burden of disease and death associated with viral hepatitis - Globally, hepatitis B and C kill approximately 1.5 million persons per year, and in the U.S. at least 15,000 Americans. Read Full Article
Hypothyroidism May Increase Liver Cancer Risk in Women
May 8 – Recent study indicates that women with a prior history of hypothyroidism may be at increased risk for liver cancer. Read Full Article.
Hepatitis B and Pregnancy: An Underestimated Issue
May 8 - Hepatitis B infection during pregnancy presents a unique set of management issues. Read Full Article.
Side Effects of Long-Term Oral Antiviral Therapy for Hepatitis B
May 8 – A review summarizes the safety profile of the five approved oral nucleoside analogs used to treat chronic HBV, including safety in pregnancy. Read Full Article.
Pharmasset Voluntarily Halts Clinical Studies with Clevudine for HBV
April 27 - Phase III studies of clevudine for the treatment of chronic HBV have been voluntarily stopped by the drug company due to concerns about study results in South Korea. Read Full Article.
Cangene's HBV Therapeutic Approved in Canada for a Second Indication
April 27 – Canada has approved HepaGam B for treating acute exposure to hepatitis B virus, in addition to already being approved by the U.S. FDA for liver transplant recipients, which makes it the only hepatitis B immune globulin product approved for both indications in North America. Read Full Article.
EASL Meeting 2009 Updates on HBV
April 27 - The European Association for the Study of Liver Disease met in Denmark April 22-26 and summaries of HBV abstracts and presentations are available at HIVandHepatitis.com
The Vaccines-Autism War: Détente Needed
April 17 - The airways smoked as activist Jenny McCarthy, mother of a child diagnosed with autism who blames vaccines, and her partner, Jim Carrey, faced off with two distinguished pediatricians representing the American Academy of Pediatrics. Read Full Article.
Report: Unscreened Blood Posed Danger
April 17 - For years, the use of unscreened blood transfusions exposed severely wounded service members and other trauma patients in Iraq and Afghanistan to the inherent risk of diseases such as HIV, hepatitis and malaria, according to medical experts who advise the secretary of defense. Read Full Article.
Vaccination Fears Over Plan for Hepatitis B Jabs for Babies
April 17 - Government health experts are considering whether to add the vaccine to a jab given to children at eight weeks in response to rising levels in Britain of hepatitis B, a blood infection that can lead to liver cancer. Read Full Article.
NJ Doctor Stripped of License After Hepatitis B Outbreak
April 10 - State regulators indefinitely stripped the license of a New Jersey doctor Wednesday after health officials say was the source of a breakout of hepatitis B among his 3,000 patients. Read Full Article.
Hundreds of Thousands Suffering from
April 10 - Hundreds of specialists gathered in Portugal to discuss new ways of treating hepatitis B, which affects over 100,000 Portuguese and at least 5% of immigrants to Portugal. Read Full Article.
Gene Clue to Asian Hepatitis Risk
April 10 - Japanese scientists report they have uncovered a genetic variant that could help explain why Asians seem especially vulnerable to the hepatitis B virus (HBV). Read Full Article.
Hepatitis B Linked to Shared Medical Gear
April 10 - When they looked for sources of patient-to-patient transmission of hepatitis B in the healthcare setting, Italian researchers found it in some unexpected places. Read Full Article.
Dr. Brian McMahon Honored by Hepatitis B Foundation with Distinguished Scientist Award 2009.
HBF co-founder and president Dr. Timothy Block (right) and HBF board chairman Joel Rosen (left) present honoree Dr. McMahon with a beautiful crystal globe award in recognition of his outstanding HBV work that has impacted the world. Read Full Article.
New Jersey Doctor in Hepatitis B Case has License Suspended
April 6 - State regulators temporarily suspended the medical license of a doctor who health officials suspect is linked to a hepatitis B outbreak in NJ. Nearly 3,000 patients have been warned to get tested after five cancer patients tested positive for HBV. Read Full Article.
New Studies Examine Elimination of Hepatitis B and C
April 6 - Researchers in Italy publish first new study that sheds light on the immunological response to coinfection with HBV and HCV and report that for patients with chronic HCV, HBV superinfection can lead to clearance of HCV. Read Full Article.
Manhattan Doctor Loses License in Hepatitis Probe
April 6 – A Manhattan anesthesiologist was barred from practicing in the state after officials said his sloppy injection techniques infected at least 11 patients with hepatitis. Read Full Article.
Kuwait Red Crescent Society Adopts Hepatitis B Awareness Campaign
April 6 – “Education is the first step towards prevention. This campaign is an opportunity to reach out to all Kuwaitis and help save lives,” says president of the Kuwait Red Crescent Society. Read Full Article.
VA Unsure of Scope of Patient Contamination
March 30 - Thousands of military veterans across the South are waiting to find out if they were exposed to hepatitis and HIV by government clinics that performed colonoscopies and other procedures with equipment that wasn't properly sterilized. Read Full Article.
Stem Cell Liver Treatment at China Hospital
March 30 - A hospital in Shanghai will begin treating patients with terminal cirrhosis of the liver by using their bone marrow stem cell since stem cells can transform themselves into different cell types that can aid a damaged liver and improve the organ's function. Read Full Article.
Used needles are causing a health crisis in India
March 30 - All over India, children scavenge in the filth for discarded syringes to sell back to hospitals and quacks. The needles, used again and again, kill at least 300,000 people a year. Read Full Article.
Health Insurers Ease Stance on Pre-Existing Conditions
March 30 – In a surprise announcement, insurers said they were willing to discard an element of their longstanding business model, under which insurance policies are priced, in part, on the basis of a person's medical condition or history. Read Full Article.
Hepatitis B Knocks Out World Title Fight
March 20 - The World International Boxing Organisation junior lightweight bout between South African Marali and Thailand Sakkreenin was cancelled as the Thai boxer has tested positive for hepatitis B. Read Full Article.
Approval of Clevudine for the Treatment of Chronic HBV in the Philippines
March 20 – The Philippine's FDA approved Clevudine for the treatment of HBV, which affects an estimated 8 million people in the country. Read Full Article.
Tattoo Parlour Sued Over Possible HIV, Hepatitis Exposure
March 20 - Owners of a Mississauga tattoo shop and the public health department are facing a $20 million lawsuit from customers who have been infected with HBV and/or exposed to HIV and HCV. Read Full Article.
Army Hospital May Have Spread Disease with Shared Insulin Pens
March 20 - More than 2,000 people may have been put at risk of AIDS and hepatitis by sharing insulin pens and cartridges in two Army hospitals, the U.S. Food and Drug Administration reports. Read Full Article.
Veterans Administration Denies Hepatitis Results
Mar. 16 – A lawsuit could be coming at the Veterans Administration for what might be thousands of risky colonoscopies performed, with at least a six patients testing positive for hepatitis. Read Full Article.
Evans Surgery Center Warns Patients May be Infected
Mar. 16 – The Evans Surgery Center in Georgia has sent out about 1,300 letters telling patients to get tested for hepatitis B, hepatitis C and HIV. Read Full Article.
Campaign Addresses Unsafe Injection Practices
Mar. 16 - A spate of hepatitis B and C infections traced to unsafe injection practices at ambulatory care centers across the country has prompted the CDC to join a new national education campaign. Read Full Article.
Tainted Syringes Behind Indian Hepatitis Outbreak
Mar. 9 – Investigators in western India traced the cause of the deadly hepatitis B outbreak to infected syringes from an operation to illegally recycle hundreds of tons of used medical equipment. Read Full Article.
Call for EU Action on Hepatitis Death Toll
Mar. 9 – Slovenian MEP Alojz Peterle calls for early diagnosis for those at risk from hepatitis: "Hepatitis represents one of the major challenges for public health in Europe." Read Full Article.
Artificial Liver Extends Lives
Mar. 9 – A new out-of-body artificial liver is extending lives by essentially doing what dialysis does for kidneys. Read Full Article.
Liver Transplant Recipients with Hepatitis B May Need Lifelong Antiviral Treatment
Mar. 9 – Patients who undergo liver transplantation for hepatitis B-related liver damage should receive lifelong antiviral treatment to keep the disease from coming back. Read Full Article.
Modasa in Battle Mode to Tame Deadly Hepatitis B
Mar. 2 – There are no signs yet of the outbreak in India being contained as the official death toll rose to 48 with a total of 154 patients already been diagnosed with HBV in and around Modasa. Read Full Article.
Hepatitis Outbreaks Blamed on Clinicians
Mar. 2 – Sloppy clinical practices caused 33 outbreaks of hepatitis B (HBV) or hepatitis C (HCV) in the past decade, reports CDC, with more than 60,000 patients tested, 448 actually infected, and several malpractice lawsuits filed. Read Full Article.
Panel Widens Recommendations on Hepatitis A Vaccine
Mar. 2 – 20 cases, including a 51-year-old grandmother who died, have gotten sick after kids have been adopted. CDC now recommends U.S. citizens who expect to have close contact with an adopted child from countries with high rates of hepatitis A should be immunized within 60 days. Read Full Article.
Transplant Patient Hanged Herself After Being Told Liver Donor had Hepatitis B
Mar. 2 – A mother of three walked out of the hospital and committed suicide after learning her new liver had been donated by a hepatitis B sufferer. Read Full Article.
IOM Committee on Chronic Hepatitis Hosts Public Meeting March 3
Feb. 16 – A free meeting hosted by the Institute of Medicine in Irvine, CA and will feature expert testimony and individual testimonies. Register at website.
Alaska Native Consortium Gets Federal Grant to Study Hepatitis B
Feb. 16 – The Alaska Consortium will use a $1 million grant from the National Institutes of Health to study hepatitis B. Read Full Article.
Lawmakers in the State of Washington May Pass Health Standards for Body Piercings
Feb. 16 – The fact that infectious diseases — such as HBV — can spread through improperly sterilized equipment has prompted state lawmakers to consider passing legislation establishing health and sterilization standards for body piercing shops. Read Full Article.
Infection Control Practices in Assisted Living Facilities: A Response to Hepatitis B Virus Infection Outbreaks
Feb. 16 – Fifty of 155 assisted living facilities in central Virginia were surveyed and 7 of these facilities shared (without cleaning between residents) finger stick devices for glucose monitoring; 17 did not offer employees HBV vaccine. Read Full Article.
Global Creative Competition
Feb. 9 – The World Hepatitis Alliance is calling on creative people around the globe to take part in the first creative competition for World Hepatitis Day on May 19, 2009. Visit website.
Mistake at Texas Army Hospital Puts Thousands at Risk
Feb. 9 – William Beaumont Army Medical Center announced that 2,114 diabetic patients treated at the hospital may be at risk for contracting blood-borne illnesses. Read Full Article.
PKIDS Launches New Website for Girls
Feb. 9 – Parents of Kids with Infectious Diseases created a new website called “Pirls”, where girls ages 11 to 15 can listen to music, play games and learn about vaccine-preventable diseases. Visit website.
Hepatitis B Policy Fellowship - Application Deadline Extended to March 9!
Feb. 9 – The Association of Asian Pacific Community Health Organizations will fund a one-year paid HBV policy fellowship in Washington, DC. Read Guidelines.
EASL Publishes Updated Guidelines for Management of Chronic HBV
Feb. 3 – The European Association for the Study of the Liver (EASL) has published updated HBV clinical practice guidelines in the February 2009 Journal of Hepatology. Read 2009 Guidelines.
More Federal Funds for Infectious Diseases in House Economic Stimulus Proposal
Feb. 2 – The House proposal allocates $335 million for programs that combat AIDS, sexually transmitted diseases (including hepatitis B) and tuberculosis. Read Full Article.
Barbers Reuse Razors
Feb. 2 – Re-using razor blades carries the possibility of transmitting blood-borne infections such as HIV, HBV and HCV, report health inspectors. Read Full Article.
HBV Prevalence in Kuwait
Feb. 2 – A panel of Kuwaiti hepatologists is developing a comprehensive treatment algorithm for chronic HBV, which supports the American Association for the Study of Liver Disease (AASLD) updated guidelines. Read Full Article.
Hepatitis Outbreaks Linked to Poor Infection Control
Jan. 26 – Thousands of patients are needlessly exposed to HBV and HCV due to the failure of health care personnel to follow basic infection-control. Read Full Article.
Nexavar® Effective for Hepatocellular Carcinoma in Asians
Jan. 26 – Researchers from 23 medical centers in Asia have reported that Nexavar® (sorafenib) is effective in patients with advanced hepatocellular carcinoma (liver cancer). Read Full Article.
Court Allows Jury to Decide if Pre-Existing Condition Exclusion Applies for Chronic Hepatitis B Patient
Jan. 26 – The court had to decide whether Yong Kim's gastric pain, evident for months before her insurance policy began, was caused by liver disease (including HBV) or diverticulitis. If caused by liver disease, then the insurance company did not have to pay for a liver transplant. Read Full Article.
"Free Hug to Hepatitis B Patients" Activity Gets Warm Response in China
Jan. 19 – Young volunteers of hepatitis B patient groups offered free hugs in the streets of Zhengzhou City, China to help decrease the stigma and discrimination against those living with HBV. Read Full Article.
Vitamin E Treatment for Children with Chronic HBV
Jan. 19 – Recent reports have shown that treatment with vitamin E in adults can normalize ALT and may also lead to HBeAg seroconversion. The first study in children that evaluated the effect of vitamin E in a placebo controlled trial was just completed. Read Full Article.
HBV Patients Demand Dialysis Facility at Hospital in Pakistan
Jan. 19 – Patients suffering from hepatitis B complained that they were not being admitted for dialysis at the People’s Medical College Hospital in Nawabshah, Pakistan. Read Full Article.
Liver Cancer and Asian Americans: A Deadly Problem with an Easy Solution
Jan. 19 – While heart disease is the number one killer of Americans, that dubious title is given to cancer among Asians in the U. S. Read Full Article.
Merck Reports Shortage of the Adult Formulation of its HBV Vaccine
Jan. 13 – Beginning in January 2009, Merck expects to experience a supply interruption in the U.S. for the adult formulation of their HBV vaccine, Recombivax HB, but does not anticipate the pediatric formulation will be affected. Read Full Article.
Drug-Induced Liver Injury in the U.S.
Jan. 13 – Research provides an interesting snapshot of clinically significant drug-induced liver injury, with the most commonly implicated single agent being amoxicillin/clavulanate. Read Full Article.
Minimal Hepatic Encephalopathy with Cognitive Impairment Common in Non-Alcoholic Cirrhosis..like HBV and HCV
Jan. 13 – Recent reports reveal that patients with minimal hepatic encephalopathy, a significant complication of cirrhosis, have an increased occurrence of traffic violations and vehicle-related accidents due to cognitive impairments. Read Full Article.
Final Statement Available for NIH Consensus Conference on the Management of Hepatitis B
Jan. 7 – The NIH brought together in Oct. 2008 an independent panel to examine the evidence on the management of hepatitis B and identify future research needs. The panel’s statement is based on a systematic literature review, expert presentations, and audience commentary. Read Final Statement.
More Than 60,000 Patients Risked Hepatitis Infections
Jan. 7 – Failure to follow basic infection practices placed more than 60,000 U.S. patients at risk for hepatitis B and C, according to a new report from the CDC. Read Full Article.
FDA Approves Most Comprehensive System to Test Donated Blood for HIV and Hepatitis B & C
Jan. 5 – A new test from Roche to screen donated blood in a single, automated assay has been approved and will increase the safety of blood supplies by identifying all 3 infections earlier than traditional blood tests. Read Full Article.
Hepatitis Education Website Available for Men Who have Sex with Men
Jan. 5 – The American Social Health Association has launched an online viral hepatitis education website for men who have sex with men that was funded by and developed in collaboration with the CDC. Read Full Article.
Discrimination Against Hepatitis B Carriers in China
Dec. 23 – Carriers are shunned and discriminated against in school and at the workplace due to widespread ignorance about the disease. View video news release.
High Burden of Illness Associated with Liver Cancer
Dec. 23 – Researchers find considerable economic impact of liver cancer in U.S. with annual healthcare costs estimated to be $454.9 million. Read Full Article.
New Television Campaign in Mandarin about Chronic HBV
Dec. 23 – Bristol-Myers Squibb launched its first-ever, non-English-language TV campaign in the U.S.to encourage Chinese Americans to talk to their doctors about HBV. Read Full Article.
Office of Minority Health Releases Goals and Strategies For Chronic HBV in Asian American Communities
Dec. 17 – The National Task Force on Hepatitis B Expert Panel convened by the HHS Office of Minority Health released today its new "Goals and Strategies to Address Chronic Hepatitis B in Asian American Native Hawaiian and Other Pacific Islander Populations. Read Press Release.
Improved Testing for HBV
Dec. 12 – Roche’s fully automated real-time PCR technology for the detection of HBV DNA been approved in Europe. Read Full Article.
Perinatal HBV Transmission and Management of Pregnant Women with Hepatitis B
Dec. 12 – Two studies, respectively, identify factors for perinatal transmission due to vaccine failure and that there is a wide diversity in managing infected pregnant women. Read Full Article.
Crucell Announces Registration of HBV Vaccine in China
Dec. 12 – Dutch biopharmaceutical company, Crucell, has announced that the Chinese authorities have released Hepavax-Gene vaccine for registration in China, which has the largest vaccine market in the world. Read Full Article.
Tenofovir Superior to Adefovir to Treat Chronic Hepatitis B
Dec. 5 – Tenofovir is superior to adefovir for the treatment of HBV according to data published in the New England Journal of Medicine. Read Full Article.
Hepatitis B Virus Screening for Internationally Adopted Children
Dec. 5 – A recent study of 1,282 adopted children with a hepatitis prevalence rate of 4% reinforces the American Academy of Pediatrics recommendations for HBV testing of international adoptees. Read Full Article.
Doctors Divided Over Hepatitis Deportation
Dec. 5 – Health officials in Dubai are divided over whether a person with hepatitis B should be deported under their law. Read Full Article.
U.K.’s First Hep B Transmission Conviction Raises Concerns
Nov. 26 – British AIDS advocates are speaking out against the United Kingdom’s first hepatitis B transmission conviction, which involves a 29-year-old man found guilty of grievous bodily harm for infecting his female partner. Read Full Article.
For 3rd Year, Liver Cancer Mortality Increases Despite Overall Decline in Cancer Deaths
Nov. 26 – According to the National Cancer Institute’s annual cancer report, both incidence and death rates from all cancers combined decreased significantly. However, for the 3rd straight year, cancers with increasing mortality included liver, esophageal and pancreatic cancer. Read Full Article.
Implementation of Newborn Hepatitis B Vaccination
Nov. 26 – More complete implementation of routine newborn HepB vaccination globally would reduce the substantial morbidity and mortality caused by HBV infections acquired by infants from infected mothers at birth. Read Full Article.
Working in Health Care Can Be Risky
Nov. 21 - A new study from the CDC shows that health care workers are more likely to die from bloodborne infections such as hepatitis B and C than people working in other occupations. Read Full Article.
Prognosis of Young HBV Patients with Hepatocellular Carcinoma
Nov. 21 - There is a distinct survival advantage for young patients diagnosed early which supports the importance of extending hepatocellular carcinoma (liver cancer) surveillance to young hepatitis B patients. Read Full Article.
Man Jailed in UK for Passing on Hepatitis B
Nov. 21 - A man who had unprotected sex and knowingly gave a woman hepatitis B, despite warnings that he should always practice safe sex, was jailed for two years. Read Full Article.
Institute of Medicine Public Meeting on Viral Hepatitis
Thursday December 4, Washington, DC
Nov. 19 - The Hepatitis B Foundation will provide expert testimony at the Institute of Medicine's Committee on Prevention and Control of Viral Hepatitis Infections free public meeting on Thursday, December 4, 2008 (1:00 to 5:00 pm) in the Board Room at the National Academy of Sciences Building in Washington, D.C,. It’s free, but please Register now!
AASLD: Pregnancy Data Reassuring to Women with Liver Transplants
Nov. 19 - Data from the National Transplantation Pregnancy Registry show the risk of medications in women with liver transplants is no higher that than seen in the general population. Read Full Article.
New Imaging Technology Accurately Identifies Liver Disease
Nov. 19 - A new study shows that an imaging technology called magnetic resonance elastography (MRE) can identify liver fibrosis with high accuracy and help eliminate the need for liver biopsies. Read Full Article.
Global Hepatitis B Initiative Launched in San Francisco
Nov. 3 - The first global hepatitis B initiative, the Asia and Pacific Alliance to Eliminate Viral Hepatitis(APAVH) was launched by the Asian Liver Center at Stanford and the U.S. CDC in collaboration with the World Health Organization to close the gaps in hepatitis B prevention and treatment. Read Full Article.
Doctors Demand Money to Fight Virus
Nov. 3 - The Australasian Society for HIV Medicine, Cancer Council, Gastroenterological Society of Australia and Hepatitis Australia warn more money is urgently needed to draw up a national strategy to deal with hepatitis B, a virus that affects up to 160,000 Australians. Read Full Article.
Vaccination Programs Prevent Millions of Deaths
Nov. 3 - According to the Global Alliance for Vaccines and Immunization (GAVI), vaccine programs targeting hepatitis and meningitis in the world's poorest countries will have saved the lives of 3.4 million people by the end of 2008. Read Full Article.
Hepatitis B Patients Sue the Bulgarian State
Oct. 28 - Four people with hepatitis B filed a collective lawsuit against the state-run National Health Insurance Fund because it refused to provide the urgent medical treatment they needed. Read Full Article.
Hepatitis B Vaccine Protection May Wane in Teens
Oct. 28 - Protection against hepatitis B appears to drop off in adolescents who got the hepatitis B vaccine beginning at birth, according to a new report. Read Full Article.
China Bans Children with HBV from Daycare Centers
Oct. 28 - Daycare centers in many provinces throughout China have banned children who test positive for Hepatitis B. Read Full Article.
NIH Consensus Conference on HBV Management
Oct. 23 - To examine the challenging and complex issues of hepatitis B, the NIH convened an independent, impartial panel this week to weigh the available evidence on the management of hepatitis B.
Read the NIH Press Release.
Read the entire NIH Consensus Development Conference Statement.
View the video webcast online.
HBF Researchers Develop Blood Test for Liver Damage
Oct. 17 - Hepatitis B Foundation scientists are developing a simple blood test that can help identify people with liver disease by detecting an antibody that is present in people with liver damage. View Video.
Genetic 'Fingerprint' Shown To Predict Liver Cancer's Return
Oct. 17 - Scientists have reached a critical milestone in the study of liver cancer that lays the groundwork for predicting the illness's path, whether toward cure or recurrence. Read Full Article.
Vitamin D Deficiency Common in Patients with Chronic Liver Disease
Oct. 17 - A research study of 118 chronic liver disease patients found that 92.4 percent had some degree of vitamin D deficiency and at least one third were severely deficient.. Read Full Article.
Elective Cesarean Delivery Lowers Risk of Vertical Hepatitis B Transmission
Oct. 8 - Elective cesarean section is associated with a lower rate of mother-to-child transmission of hepatitis B virus in patients with high viral loads. Read Full Article.
NIH Launches New Web Site for Parents
Oct. 8 - A new website from the NIH describes why research in children is important, how studies are conducted, and what measures are taken to protect participants' safety and privacy. Read Full Article.
Obesity Drugs Fight Flu, Hepatitis, HIV
Oct. 8 - Current anti-obesity drugs that help slow metabolism may be used to fight infections such as influenza, hepatitis and HIV, according to a new study. Read Full Article.
Study Finds Association Between Hepatitis B and Pancreatic Cancer
Oct. 1 - People with pancreatic cancer are more likely than those without the disease to have been infected with the hepatitis B virus, a study has shown for the first time. Read Full Article.
Children Vaccinated Against Hepatitis B Not at Increased Risk of MS
Sept. 26 - The American Academy of Neurology reports that the majority of children vaccinated against hepatitis B are not at an increased risk of developing multiple sclerosis. Read Full Article.
Students Getting Tested for Diseases after Needle Incident
Sept. 26 - Parents are in shock after learning their kids were pricked by needles at Goshen Middle School with more than a dozen students tested for HIV, HBV and HCV. Read Full Article.
FDA Requests Further Information on Merck´s Experimental Hepatitis B Vaccine
Sept. 26 - The FDA placed a hold on clinical trials for Heplisav, a new hepatitis B vaccine, because of safety concerns when a patient was diagnosed with a rare disease that causes blood vessels to inflame. Read Full Article.
CDC Expands Hepatitis B Testing Recommendations
Sept. 19 - The CDC today issued new recommendations designed to increase routine hepatitis B testing in the U.S. and new guidance for the medical management of individuals chronically infected with hepatitis B. Read Full Article.
Nokia Still in Court Over Alleged HBV Discrimination
Sept. 19 - The Beijing Yirenping Centre, one of China's most highly visible watchdogs on HBV, has called for Nokia to honestly face the problem of workplace discrimination. Read Full Article.
Researchers Invigorate "Exhausted" Immune Cells
Sept. 19 - Researchers have found a novel tool that may advance the development of new therapies for diseases such as HIV, hepatitis B and C, and cancer. Read Full Article.
Epidemiology of HBV in Truck Drivers in Brazil
Sept. 19 - Research findings confirm truck drivers in Brazil are at high risk for HBV and the importance of a public health policy to address this group. Length of profession, time away from home, and history of STDs were independently associated with HBV infections. Read Full Article.
Pregnancy and Liver Transplantation
Sept. 15 - Despite an increased risk of maternal and fetal complications, pregnancy in transplant recipients can have a successful outcome. Read Full Article.
Prevalence of HBV Infection Among Women of Reproductive Age
Sept. 15 - Researchers concluded that screening for HBsAg during pregnancy is still necessary for reduction of perinatal HBV transmission even in countries with low HBV prevalence. Read Full Article.
New Approach To Treatment of HBV Infection
Sept. 15 - Researchers are studying the efficacy of DNA inhibitors on HBV infection and replication to assess the potential for early intervention therapy. Read Full Article.
Roche Wins FDA OK for HBV DNA Test
Sept. 5 - The first FDA test for quantifying hepatitis B DNA can be used by doctors to establish a baseline level of infection and assess responses to therapy. Read Full Article.
HBV Reactivation Leads to High Risk of Liver Failure and Death
Sept. 5 - New test results revealed that liver-related mortality was significantly higher in individuals who experienced hepatitis B reactivation after previously resolved infection than in those with acute hepatitis. Read Full Article.
Newest Disease-Spreading Fear: Handcuffs
Sept. 5 - A Canadian company warned a national police conference in Montreal that dirty handcuffs can transmit herpes, HIV, influenza and hepatitis B. Read Full Article.
Tired of Hep B, Woman Sets Herself on Fire
Sept. 5 - A 22-year-old woman allegedly fed up with Hepatitis B decided to kill herself Thursday by setting herself on fire. Read Full Article.
Clinical Trials for Treatment to Prevent Recurrence of Liver Cancer Begin
Sept. 2 - Enrollment has begun in a Phase 3 study to evaluate Nexavar (Sorafenib) tablets for treatment following surgery or local radiation for patients with primary liver cancer. Read Full Article.
Anesthesiologist Allegedly Spreads Hepatitis
Sept. 2 - A New York anesthesiologist has been suspended and is accused in lawsuits of infecting at least 14 patients with hepatitis B and C. Read Full Article.
Prior Non-responders Respond Well to a Double Dose of Combined Hepatitis A and B Vaccine
Aug. 22 - Revaccination of non-responders to the standard hepatitis B vaccine regimen with a double dose of the combined hepatitis A and B vaccine appears to be highly effective. Read Full Article.
UN Health Agency Spotlights Impact of Hepatitis B Virus
Aug. 26 - The United Nations health agency is launching a new information campaign to highlight the impact of the hepatitis B virus, which is currently found in about 2 billion people worldwide despite being preventable by vaccine for more than 25 years. Read Full Article.
Edmonton's ViRexx Upbeat Over Hep B Vaccine
Aug. 22 - An important first step in the in the development of an effective Hepatitis B therapeutic vaccine was reported by Canadian company ViRexx at the 2008 International HBV Meeting. Read Full Article.
High HBV Viral Load at Surgery Tied to Liver Cancer Return
Aug. 22 - In patients undergoing liver resection for hepatocellular carcinoma related to hepatitis B virus infection, viral load at the time of surgery is predictive of cancer recurrence. Read Full Article.
India's Hepatitis B Virus Drug Market Grows
Aug. 22 - The hepatitis B drug market in India will grow ten-fold by 2012 due to increasing wealth, urbanization, and disease awareness. Read Full Article.
Researchers Create Blood Cells In The Lab
Aug. 22 - New technology will make vast quantities of blood available without the need for donors which reduces the risk of transmitting HBV, HCV and other diseases. Read Full Article.
Nano Vaccine For Hepatitis B Shows Promise For Third World
Aug. 18 - Scientists report a novel "needle-free" nasal immunization method that could provide a safe and effective alternative HBV vaccine for countries where refrigerated storage and sterile needles are scarce. Read Full Article.
Conference Inspires Youth to be Hep B Leaders
Aug. 18 - One hundred students from all over the U.S. will learn about the fight against hepatitis B and how to educate their community at the 6th Annual Youth Leadership Conference on Asian and Pacific Islander Health at Stanford University. Read Full Article.
Hepatitis B Genotypes Could Determine Liver Cancer Risk
Aug. 18 - New data may help identify individuals who are at an increased risk for liver disease progression based on a particular HBV genotype or mutation. Read Full Article.
FDA Approves Viread for Chronic Hepatitis B in Adults
Aug. 11 - The U.S. FDA has granted marketing approval for Viread (tenofovir) for the treatment of chronic HBV in adults. Viread has been available in the U.S. as a treatment for HIV infection in adults since 2001, and represents an important new treatment option. Read Full Article.
People Living With HIV/AIDS In Canada Have Difficulty Obtaining Organ
Aug. 11 - The majority of liver transplants in Canada are performed on people living with HBV or HCV. Many also have HIV. "I'm not asking for special access for those who are coinfected, just fairness in access," says leading physician. Read Full Article.
New Recommendations For Disaster Survivors
Aug. 11 - New vaccine recommendations were released by the CDC to help injured disaster survivors that may be at risk for infection from blood-borne viruses such as hepatitis B and C. Read Full Article.
Biologists Develop Machine To Remove Viruses From Blood
Aug. 11 - In a method similar to dialysis, the hemopurifier is designed to filter out viruses and toxins before they attack organs. Read Full Article.
Low Hep B Vaccination Rates Seen in Newborns
Aug. 4 - Results of a CDC survey indicate that only about 50% of newborns receive a dose of hepatitis B vaccine before hospital discharge. Read Full Article.
Structure of Hepatitis B Mapped By Spraying Virus Aug. 4 - Researchers have mapped the structure and composition of the hepatitis B virus using a newly developed method. Read Full Article.
U.S. Tightens Visas with Vaccine Requirements
Aug. 4 - New vaccine requirements, including HBV, will affect anyone who is applying for an immigrant visa for entry into the U.S. Read Full Article.
First and Only Drug Therapy Approved in China for Liver Cancer
Aug. 4 - The FDA of China has approved Nexavar (sorafenib) tablets for the treatment of patients with unresectable or metastatic liver cancer which significantly improves overall survival rates. Read Full Article.
Demographic Variations Seen in Liver Cancer Incidence
July 28 - The incidence of hepatocellular carcinoma in the US differs significantly by sex, ethnicity, and age at diagnosis according to a new study. Read Full Article.
Two Studies Look at Promising Therapies for Liver Cancer
July 28 - Recently published studies produced promising data on experimental therapies for liver cancer: the systemic chemotherapy drug sorafenib (Nexavar), and combination therapy using doxorubicin-eluting beads plus radiofrequency ablation. Read Full Article.
Adults Need Vaccines - But Most Don't Get Them
July 28 - Low immunization rates represent a national public health crisis according to infectious-disease experts. Read Full Article.
Olympians Warned Not to Celebrate Beijing with Tattoos
July 21 - The tradition for some athletes to celebrate their participation in the Olympic Games in Beijing by getting a tattoo "seriously risks" the transmission of blood-borne diseases such as hepatitis B. Read Full Article.
Hepatitis B Activists Rejoice as China Unblocks Web Site
July 21 - A web site for people in China living with hepatitis B is back online after being blocked for 43 days by government authorities. Read Full Article.
Obesity and Diabetes Are Linked to Increased Risk of Liver Cancer
July 21 - The finding that both obesity and diabetes are predictors of liver cancer may shed some light in preventing this fatal diagnosis. Read Full Article.
Excellent Response Rate in Previous Nonresponders to Hepatitis B Vaccine
July 21 - Revaccination with a double dose of the combined hepatitis A and B vaccine is highly effective in nonresponders to the standard hepatitis B vaccine regimen. Read Full Article.
Rates of Hepatitis B on the Rise
July 14 - The number of teenagers in the U.K. being treated for hepatitis B and C has more than quadrupled over the last year. Read Full Article.
New Law Adds to List of Deportable Diseases
July 14 - Tuberculosis and hepatitis B are now included in the list of deportable diseases, a Dubai health official has confirmed. Read Full Article.
Hepatitis B Patients Face Broad Discrimination in China
July 14 - The Yirenping Center in Beijing has created a forum for hepatitis B patients who seek information and basic human rights that enable them to fight discrimination. Read Full Article.
Nevada: "Aid from Congress Isn't Coming"
July 3 - Prior to submitting an emergency spending bill to the President, federal lawmakers eliminated $5 million in money set aside to help defray costs associated with a hepatitis outbreak in Las Vegas. Read Full Article.
Entecavir Boosts Hepatitis B Response After Lamivudine Failure
July 3 - After 52 weeks of treatment, entecavir lowered DNA levels and increased the loss of e-antigen compared with lamivudine. Read Full Article.
Children Must Be Protected Against Hepatitis
July 3 - Hepatitis B can be prevented through the widespread use of vaccines; however, currently no mass vaccination programs exist in the UK where strains of the virus are becoming increasingly resistant to treatment. Read Full Article.
Patient Safety Measures Draw Mixed Reaction
June 25 - NYC Gov. David A. Paterson's measures aimed at improving patient safety and putting more teeth into physician discipline drew a mixed reaction from experts in health care and the legal profession. Read Full Article.
Hepatitis B Almost Eradicated in Cuba
June 25 - With 17 cases reported in 2007 and only four so far this year, Cuba is ready to eradicate hepatitis B transmission with a highly effective vaccination program. Read Full Article.
Countdown to Finish Line Event for John Ellis Cycling Tour!
June 20 - 17 year old John Ellis is close to completing his 1,100 mile tour from Pensacola to Philadelphia in the Believe in the Cure Cycling Tour. Learn more about this extraordinary teen with hepatitis B and Make a Donation in his honor!
Adolescents May Require Hepatitis B Vaccine Boosters
June 20 - Widespread vaccination of infants and children against hepatitis B has dramatically reduced the incidence of the disease, but it remains unclear how long this protection lasts. Read Full Article.
Edmonton Dentist Tests Positive for Hepatitis B
June 20 - After testing positive for hepatitis B, a Canadian dentist quit his practice and 1,400 patients will be notified about the possible exposure. Read Full Article.
PharmaEssentia Announces Milestone in Development of New Interferon
June 20 - Studies show a new PEG-interferon-alpha drug for hepatitis B and C is particularly long-lasting compared to the two other pegylated-interferon drugs currently on the market. Read Full Article.
Warnings Over Body Piercing Boom
June 16 - Belly button piercings are common among young women. Problems over botched body piercings and the risk of contracting hepatitis B or C could place a "substantial burden" on the health care system in the near future, a British study says. Read Full Article.
Hepatitis Alert Follows Tokyo Stabbings
June 16 - Tokyo police today warned of a potential hepatitis B risk for persons who came in contact with blood following the mass killing in the Akihabara district. Read Full Article.
HBV Website in China Shut Down By Government
June 16 - The Hepatitis B Camp Network, the most popular website in China for people living with HBV, has been closed down for the second time in six months. Patients rights advocates have voiced strong condemnation. Read Full Article.
How, Why and Who Should Perform Liver Biopsy in Chronic Liver Diseases
June 6 - Most authorities consider liver biopsy to be the "gold standard" in the prognosis and management of liver fibrosis. Read Full Article.
Chronic HBV Patients with Normal ALT May Experience Active Liver Disease Progression
June 6 - Studies have shown that liver disease progression can occur in people with normal or only minimally elevated ALT and AST. Read Full Article.
Beirut Health Ministry Launches Campaign to Fight Viral Hepatitis
June 6 - A new national awareness campaign highlights the importance of health education, early detection of hepatitis and vaccination. Read Full Article.
Teens Biking 1100 Miles for Hepatitis B Awareness
June 3 - Best friends John Ellis and Jamaal Warren recently graduated from Tate High School and will spend the next three weeks of their summer vacation together on a 1,100-mile bike ride from Pensacola to Philadelphia to raise awareness about hepatitis B. Read Full Article.
9.2 Million People in Peru Receive Hepatitis B Vaccine
June 3 - Millions of Peru's people were vaccinated in the past two months as a part of a campaign against HBV, cirrhosis and liver cancer. Read Full Article.
Hepatitis B Rise Leads to Migrant Screening
June 3 - One in ten of the Chinese immigrant population in Britain is carrying the hepatitis B virus, which is leading to calls for all immigrants to be screened upon entering the country. Read Full Article.
United States Seeks New Hepatitis Blood Donation Rules
May 23 - The U.S. FDA now recommends that people who have repeated false positive tests for hepatitis B, but who are subsequently found to be uninfected, be allowed to donate blood. Currently, these people are indefinitely deferred from blood donation. Read Full Article.
Canadians with Hepatitis B and C Demand Action to Tackle Life Threatening Disease
May 23 - Canadians with hepatitis B and C are demanding the government demonstrate their commitment to prevention, treatment, and research with funding proportionate to the impact and burden of this health issue. Read Full Article.
Fight Against Hepatitis B Also a Battle Against Fear
May 23 - Australia's former deputy prime minister and health minister Brian Howe speaks out on behalf of the country's National Hepatitis B Alliance that is calling for a national action plan. Read Full Article.
New Treatment Choice for Adolescents with Chronic HBV
May 23 - Studies suggest that pegylated interferon is a good therapeutic option for teens with HBeAg negative chronic hepatitis B. Read Full Article.
Congressional Briefing on Hepatitis B Held Today
May 20 - In observation of National Hepatitis B Week (May 19-23), the Hepatitis B Foundation and the Association of Asian Pacific Community Health Organizations are hosting a Congressional Briefing titled Zero Tolerance for Hepatitis B: the Health Needs of Women and Children. Read Press Release.
Today is World Hepatitis Day
May 19 - More than 200 patient advocacy groups from around the globe will observe World Hepatitis Day to increase awareness of the shocking statistic that one in 12 people on the planet are living with hepatitis B or hepatitis C. Read more.
California Legislator Shares Her Story About Hepatitis B
May 16 - California Assemblywoman Fiona Ma tells about her life with hepatitis B and the "San Francisco Hep B Free" campaign to raise awareness about this deadly but preventable disease. Read Full Article.
HBV Patients in China Unite on World Hepatitis Day
May 16 - HBV patients in China launched a campaign called "Fly the Jade Kite" to raise awareness about discrimination in conjunction with World Hepatitis Day on May 19th. Read Full Article.
National Committee Leads World Hepatitis Day Campaign in Egypt
May 16 - Screening, vaccination, ultrasound, consultations and seminars will be free to the public in observation of World Hepatitis Day. Read Full Article.
Hepatitis B Experts at Loggerheads
May 12 - A top Australian virologist warned that monotherapy has needlessly created resistance to antiviral drugs by giving a survival advantage to mutated strains of the virus. Read Full Article.
"Am I Munber 12?"
May 9 - The World Hepatitis Alliance has kick-started the 'Am I Number 12?' campaign to raise awareness about a disease that is claiming 1.5 million lives per year. The objective is to launch World Hepatitis Day 2008 on May 19th that will highlight the global burden of chronic hepatitis B and C in 12 major cities. Read Full Article.
Review Finds "Worrying" Gaps in Drug Treatment Services
May 9 - Inconsistent practices in key areas of delivery such as testing and treatment are failing to reduce hepatitis B and C in drug users in the UK. Read Full Article.
Hepatitis B Patients on Pegasys Achieve Positive Treatment Response
May 9 - New data show that a significant number of patients with chronic hepatitis B treated with a pegylated interferon achieved HBsAg clearance. Read Full Article.
Asian Americans Confront Unique, Unusual, and Unnecessary Cancer Burden
May 9 - Activities throughout the month of May are planned to raise awareness about the disproportionate rates of liver cancer among Asian Americans resulting from infections such as hepatitis B and C. Read Full Article.
Student Plans 1,100 Mile Bike Trip to Promote Awareness of Hepatitis B
May 5 - Seventeen year-old John Ellis who was recently diagnosed with HBV will cycle from his hometown of Pensacola Florida to Philadelphia PA, the home of the Hepatitis B Foundation to raise awareness about the disease. Read Full Article.
Hepatitis B Patients Getting Short-Changed by Province
May 5 - Nearly 100,000 Ontarians living with chronic hepatitis B are not getting access to the most effective treatments because the drugs are not covered by Canadian health insurance. Read Full Article.
Pregnancy and Liver Disease
May 5 - Although liver disease does not occur frequently during pregnancy, when it does, it can cause significant morbidity and mortality for both fetus and mother. Read Full Article.
China has 93 Million HBsAg Carriers
Apr. 25 - According to the Ministry of Health, about 7.18 percent of the total population are hepatitis B surface antigen (HBsAg) positive. Read Full Article.
Liver Cancer Screening Improves Survival of Patients with Chronic Hepatitis B or C
Apr. 25 - Survival of patients with HCC detected by screening has improved in recent years due to increased chance of curative treatment. Read Full Article.
HBV Immunization Program Successful in Italy
Apr. 25 - Acute hepatitis B incidence has decreased dramatically since universal vaccinations were introduced in Italy, but challenges remain. Read Full Article.
Get Your Jabs Before Heading to China for 2008 Olympics
Apr. 21 - Those heading to China for this summer's Olympic Games should ensure they are properly vaccinated beforehand. Read Full Article.
U.S. Senator Seeks Funds for Hepatitis Scare
Apr. 21 - Senate Majority Leader Harry Reid is seeking $26 million in emergency funds from Congress to help deal with the hepatitis C crisis in Southern Nevada. Read Full Article.
Hepatitis B Tied to Bile Duct Cancer
Apr. 21 - The results of a recent study suggest there is an association between HBV infection and an increased risk of bile duct cancer which is very difficult to treat. Read Full Article.
Slightly Abnormal Blood Test May Point to a 'Silent' Form of Hepatitis B
Apr. 14 - A study showing the presence of hepatitis B DNA in the absence of actively replicating virus means that even patients who are not ill with the disease could be infectious. Read Full Article.
Hepatitis B Virus Triggers Cell 'Suicide' in Chronically Infected Patients
Apr. 14 - Researchers have found that T cells are an important factor in determining why some people can fight the Hepatitis B virus off successfully while others can't. Read Full Article.
Experts Renew Calls for In-Prison Needle Exchanges
Apr. 14 - Researchers have called for prison-based needle exchanges as findings show a high rate of syringe sharing amongst incarcerated individuals which leads to greater risk of transmitting infectious diseases such as HBV. Read Full Article.
State to be Sued by Hepatitis B Carriers, Who Top 1 Million
Apr. 7 - People who are believed to have contracted hepatitis B through mandatory vaccination against infectious diseases, including polio, measles and influenza, plan to file a series of lawsuits against the Japanese government for relief measures to help treat the disease. Read Full Article.
National Hepatitis B Campaign Launched in Egypt
Apr. 7 - The campaign, known as a "University Awareness Campaign," it seeks to provide free HBV vaccinations for final year medical students - a segment at great risk of coming into contact with the virus, it added. Read Full Article.
Canadian Government Expands Hepatitis B Drug Coverage
Mar. 31 - The British Columbia (BC) government will cover adefovir (Hepsera) and entecavir (Baraclude) for the treatment of hepatitis B, which affects about 30,000 to 60,000 individuals and is estimated to cost about $3 million per year. Read Full Article.
Former Fashion Fair model with HBV Honored for Her Advocacy
Mar. 31 - Former model Rosie M. Butler lives with chronic HBV and has dedicated her life to raising funds for liver disease research at the University of Alabama, which honored her efforts with the creation of the "Rosie M. Butler Endowed Support Fund for Viral Hepatitis". Read Full Article.
Turning the Tide of Liver Cancer Among Asians
Mar. 31 - A largely preventable cancer is expected to become more common in the United States in coming years. No, it's not lung cancer -it's liver cancer, which is the fastest growing cancer in the U.S. and the third most common cause of cancer death worldwide. Read Full Article.
Viread Approved for Treatment of Chronic HBV in Europe
Mar. 21 - Viread (tenofovir), an antiviral drug used for treating HIV/AIDS, has been recommended for approval by a European Commission as a treatment for hepatitis B. Read Full Article.
Scientists Unite to Fight Disease
Mar. 21 - More than 120 Chinese and European Union scientists have gathered in Shanghai to seek ways to cooperate in the fight against infectious diseases such as influenza, tuberculosis and hepatitis B. Read Full Article.
Feeling Liverish.Maybe It's Your Liver?
Mar. 21 - According to traditional Chinese medicine, people with chronic hepatitis B should be especially vigilant in spring and watch their diet, exercise regularly, get plenty of rest and maintain a positive outlook. Read Full Article.
Hep B Vaccine Trial Placed on Hold
Mar. 21 - US regulators have temporarily suspended clinical development of Heplisav, an investigational hepatitis B vaccine after a serious adverse reaction. Read Full Article.
Baby of Hep B Mother Must Be Vaccinated, Judge Rules
Mar. 17 - A judge has ordered a mother with chronic hepatitis B to have her newborn baby vaccinated against the infectious disease, capping an unusual case that underlined the continuing fear of immunization among some Canadians. Read Full Article.
Taking Hepatitis B Drug with Interferon May Be Dangerous
Mar. 17 - Canadian health officials are warning consumers being treated with Sebivo (telbivudine) for hepatitis B not to combine the medication with any interferon products because of potentially serious drug interactions. Read Full Article.
Chronic Hepatitis B: Preventing, Detecting, and Managing Viral Resistance
Mar. 17 - HBV antiviral drug resistance may be best prevented by using a combination of nucleoside and nucleotide drugs with different resistance profiles for first-line treatment of chronic hepatitis B. Read Full Article.
HBF Testifies Before Congress for More HBV Funding
Mar. 13 - HBF President Dr. Timothy Block was invited by U.S Representative David Obey, Chairman, Committee on Appropriations, Subcommittee on Labor, Health and Human Services, to present testimony today advocating for more HBV funding in the fiscal year budget 2009. Dr. Block cited the recent Nevada outbreak as a dramatic example of how the nation is facing a major public health challenge that cannot be ignored. "If we don't act with urgency, more and more people will suffer from chronic hepatitis," he said. Read Dr. Block's complete HHS Testimony.
FBI Investigating Clinic in Las Vegas Hepatitis Outbreak
Mar. 10 - The FBI is investigating possible Medicare fraud at a Las Vegas surgical center believed to have spread hepatitis by reusing syringes and vials of medication. Read Full Article.
Effects of Kava on the Liver
Mar. 10 - Recent evidence has begun to emerge about adverse affects to the liver caused by a popular herbal remedy to treat anxiety, insomnia and tension. Read Full Article.
Slimming Aids and other Herbal Remedies Can Effect Liver
Mar. 10 - In recent years, dietary supplements have been implicated in causing severe and sometimes fatal hepatotoxicity. Read Full Article.
CDC Head: Problems at Nevada Clinic Could Be 'Tip of Iceberg'
Mar. 6 - Nevada health officials are trying to contact about 40,000 patients who had procedures at the Endoscopy Center of Southern Nevada between March 2004 and Jan. 11, 2008, advising them to be screened for hepatitis B, hepatitis C and HIV. Read Full Article.
Acetaminophen and Liver Damage at a Glance
Mar. 5 - Tylenol is currently the most popular painkiller in the U.S. Americans take over 8 billion pills of Tylenol each year. But is it safe? Read Full Article.
Waning-off Effect of Serum Hepatitis B Surface Antibody
Mar. 5 - A recent study of Taiwanese university students revealed that booster doses of HBV vaccine should be considered to effectively protect against future hepatitis B infection. Read Full Article.
Family of Liver Cancer Genes Discovered
Mar. 5 - The discovery of two genes that predispose individuals to hepatocellular carcinoma may prove to offer a valuable tool in diagnosis and treatment. Read Full Article.
Hepatitis C Fear for Thousands in Nevada
Feb. 29 - Six people who underwent endoscopic procedures at a Nevada clinic have contracted hepatitis C, but 40,000 more should be tested for it, as well as for HBV and HIV, said health officials. Read Full Article.
Japan's Hepatitis B Victims Plan to Sue Government
Feb. 29 - Japan's hepatitis B sufferers infected through contaminated vaccine syringes plan to sue the government for financial and medical assistance after a recent victory by hepatitis C patients. Read Full Article.
Hepatitis E Virus May Cause Chronic Liver Disease
Feb. 29 - In addition to vaccinating against hepatitis A, the hepatitis B vaccine should be offered to anyone visiting areas where HBV is widespread. Read Full Article.
Combination Vaccine Recommended for International Travelers
Feb. 29 - Contrary to widely held beliefs, hepatitis E infection can lead to chronic liver disease in transplant patients. Read Full Article.
Toward A Banana-based Vaccine for Hepatitis B
Feb. 25 - Bananas appear to be an ideal production and delivery vehicle for a plant-based, oral HBV vaccine. Read Full Article.
Risk of Peripheral Neuropathy with Sebivo (Telbivudine)
Feb. 25 - According to new warnings, chronic hepatitis B patients who are being treated with Sebivo should be carefully monitored for signs of peripheral neuropathy. Read Full Article.
Too Much Fast Food and Too Little Exercise Harm the Liver
Feb. 25 - Too much fast food and not enough physical activity can result in sharp increases in liver damage. Read Full Article.
California Bill Aims to Boost Culturally Appropriate HBV Prevention and Management
Feb. 15 - New legislation in California would expand Medicaid coverage to people with chronic hepatitis B and provide grants for multicultural HBV public awareness campaigns. Read Full Article.
An Enormous HBV-Related Liver Disease Burden Projected in Vietnam by 2025
Feb. 15 - Hepatitis B is the major cause of chronic liver disease in Vietnam, with a projected incidence of 8 million by 2025. This means the HBV-related liver disease burden will be enormous. Read Full Article.
West Bengal Gets Aid to Fight Liver Diseases
Feb. 15 - With terminal liver diseases on the rise, the West Bengal Liver Foundation seeks to address chronic hepatitis B, which affects an estimated 30 million people (3-4% of the Indian population). Read Full Article.
Anti-fungal Tablets Linked to Liver Deaths
Feb. 12 - Three people have died and several others have suffered serious liver reactions after taking Lamisil, a popular medication to treat fungal infections. Read Full Article.
Tattoos May Be Tomorrow's Vaccines
Feb. 12 - Using tattoos, scientists have found a more effective way to deliver therapeutic vaccines to fight cancer and other serious conditions. Read Full Article.
Innogenetics Secures Key Hepatits B Testing Patent
Feb. 12 - A Belgium biotech company has secured a US patent for hepatitis B drug resistance testing which is highly recommended for all hepatitis B antivirals. Read Full Article.
Two Drug Firms Charged in France over Hepatitis Vaccine
Feb. 4 - GlaxoSmithKline and Sanofi Pasteur are facing charges in France that their hepatitis B vaccine caused serious side effects among 1,300 patients between 1994 and 1998. The companies deny any wrongdoing. Read Full Article.
Cure for Cirrhosis?
Feb. 4 - Scientists have developed a drug that inhibits the activation of the protein that causes tissue scarring. The discovery may lead to new drugs to treat fibrosis/cirrhosis and other types of tissue scarring. Read Full Article.
Double-Dose Hepatitis B Revaccination has Good Results in HIV-positive Patients
Feb. 4 - Use of a double-dose of hepatitis B virus vaccine in HIV-positive patients who did not respond to standard vaccination has a 50% success rate, according to a Dutch study. Read Full Article.
Too Few U.S. Adults Getting Needed Vaccinations
Feb. 4 - According to US health officials, a concerted effort is needed to raise adult immunization rates to protect from a range of dangerous diseases. Vaccinations aren't only for children, adults need them, too. Read Full Article.
Doctors Report Transplant Breakthrough
Jan. 28 - Doctors have developed a technique that could free many patients from having to take anti-rejection drugs for the rest of their lives. The treatment involves weakening the patient's immune system, then giving the patient bone marrow from the person who donated the organ. Read Full Article.
Organizing Organ Donation
Jan. 28 - To help boost organ donation rates in Britain an opt-out, rather than an opt-in system was recently proposed. Everyone would be presumed to be a willing organ donor at death unless he or she had stated otherwise. This opt-out system already exists in Europe and has also been proposed for the U.S. Read Full Article.
Genes Key To High Liver Cancer Rates In Men
Jan. 28 - A fundamental difference in the way males and females respond to chronic liver disease at the genetic level helps explain why men are more prone to liver cancer, according to a recent study. Read Full Article.
Hepatitis B Exacerbation May Occur in Women After Giving Birth
Jan. 28 - Researchers in the Netherlands investigated the evolution of liver disease during and after pregnancy in women with chronic HBV and concluded that a significant increase in liver inflammation often occurs after pregnancy that may be due to a reactivation of the immune system after delivery. Read Full Article.
Impact of Hepatitis B on Quality of Life
Jan. 21 - Infection with chronic HBV causes considerable distress to individuals and results in substantial global economic loss through costs of treatment and lost productivity. However, the impact on the quality of life of patients is not well studied. Read Full Article.
Chinese Army to Vaccinate All New Recruits Against Hepatitis B
Jan. 21 - The Chinese People's Liberation Army has begun to vaccinate all new recruits against hepatitis B In an effort to reduce the HBV rate in China. Plans to revise existing rules on vaccination to provide vaccine to all army personnel are underway. Read Full Article.
San Francisco Medical Center to Use Gene Therapy
Jan. 21 - California Pacific Medical Center announced this week that it has become the first medical research institute to use a gene-silencing therapy to treat hepatitis B. This new therapy prevents the virus from multiplying by effectively paralyzing it and making it unable to create infectious virus particles.. Read Full Article.
Nucleonics Initiates HBV Clinical Trial with New eiRNA Therapeutic
Jan. 14 - Nucleonics announced that it has begun treating HBV patients in a Phase I study with NUC B1000, which is designed to lower viral antigen load as well as viral DNA load. Read Press Release.
Blood Scare for British Troops
Jan. 14 - Six British civilians and 18 soldiers working in Afghanistan or Iraq may have been exposed to contaminated blood provided by the US military and face an agonizing wait to learn the results of their own tests for blood infections. Read Full Article.
Emergent Hepatitis B Drug Moves to Next Stage
Jan. 14 - Emergent BioSolutions is progressing to the next stage in its study of a therapeutic hepatitis B vaccine, which is anticipated to increase the potential of clearing the virus and eliminating the need for long-term antiviral therapy. Read Full Article.
Premarital AIDS and Hepatitis Tests Become Mandatory
Jan. 14 - Hepatitis B and C and HIV will join the other mandatory medical tests that Saudi couples who are about to marry will have to undergo in order to be issued a marriage certificate. Read Full Article.
Potency of Tenofovir in Chronic Hepatitis B: Mono or Combination Therapy?
Jan. 8 - The concept of combination therapy has long been established as the paradigm of therapy for a number of other chronic infections to diminish or delay occurrence of resistance. The combination regimens should be compared to monotherapy with our most effective nucleos(t)ide analogues, such as entecavir and tenofovir, according to new article in J. of Hepatology. Read Full Article.
The Underestimated Risk of Hepatitis A and Hepatitis B: Benefits of an Accelerated Vaccination Schedule
Jan. 7 - Three doses of TwinrixR administered over three weeks and a fourth at 12 months provides rapid initial protection for most individuals for whom the standard 6-month vaccination schedule would not be suitable, including last-minute travelers to HAV or HBV endemic areas and short-term correctional facility inmates. Read Full Article.
Long-Term Peginterferon Shows Promise Against Hepatitis B in Pilot Study
Jan. 7 - Hepatitis B e antigen (HBeAg)-negative patients treated with pegylated interferon alfa-2a over a period of sixty weeks showed a higher rate of sustained virologic response than that usually achieved with the standard treatment duration of 48 weeks. Read Full Article.
Shorter Legs Linked To Liver Disease
Jan. 7 - Short legs are linked to an increased risk of liver disease, suggests a new study. The research contributes to a growing body of evidence on the link between leg length and health. Read Full Article.
Mortality Related to Chronic HBV and HCV in France
Dec. 31 - In France, 4,000-5,000 deaths related to HCV and HBV infection occurred in 2001. Alcohol consumption and HIV infection were important co-factors. Read Full Article.
Deaths in China from Hepatitis B Prompt Bristol, Glaxo Urgency
Dec. 31 - In China, hepatitis B kills about 808 people daily. Now, a growing middle class may open doors for Western pharmaceutical companies such as Bristol-Myers Squibb & Co. and GlaxoSmithKline Plc, which sell drugs to treat the virus. Read Full Article.
HBF Scientists Discover Possible New Alternative to Liver Biopsy for Early Detection and Monitoring
Dec. 24 - Scientists working at the Hepatitis B Foundation, in partnership with Drexel University College of Medicine, report they may have discovered a reliable alternative to liver biopsy for the early detection of liver fibrosis and cirrhosis, which afflict more than 5 million Americans, in upcoming J. of Virology. Read Press Release.
HBF Publication Reports Significant Underestimation of Chronic HBV in the U.S.
Dec. 24 - Hepatitis B Foundation reports there are closer to two million Americans chronically infected with HBV in the J. of Viral Hepatology. New calculations reveal at least one million Americans may be missing from official estimates of chronic HBV rates in the U.S. Read Full Article.
San Francisco Hospital to Help with HBV in Vietnam
Dec. 24 - A San Francisco medical center, led by Dr. Robert Gish, is teaming up with a hospital in Ho Chi Minh City to help combat hepatitis B. Read Full Article.
FDA: Tattoos Can Endanger Health
Dec. 24 - The U.S. Food and Drug Administration is warning consumers to consider potential health and safety risks before getting tattoos since dirty needles can transmit blood-borne infections like hepatitis B. Read Full Article.
Living Donor Liver Transplantation for HBV Related
Dec. 24 - Living donor liver transplant has become established as a viable clinical option for chronic HBV patients with cirrhosis in Turkey. Prophylactic antiviral treatment and low dose HBIg provide excellent results for transplant recipients. Read Full Article.
Hong Kong Study Reveals "Public Lacks Awareness of Hepatitis B"
Dec. 17 - Despite being aware that hepatitis B can lead to liver cancer, many carriers of the disease have not been properly screened for the virus nor do they know how to manage their condition, according to a survey of 3,318 people conducted by Hong Kong researchers. Read Full Article.
Exacerbation of Chronic Hepatitis B Infection After Delivery
Dec. 17 - In women with chronic HBV, a significant increase in liver inflammation often occurs following pregnancy due to a reactivation of the immune system. Close monitoring and treatment may be needed. Read Full Article.
Association Between Herbalife Nutritional Supplements and Acute Hepatotoxicity
Dec. 17 - Individuals suffering from underlying liver disease such as HBV should exercise caution in the consumption of Herbalife products, according to an Israeli University study. Read Full Article.
Comparison of Interferon-á and Lamivudine Treatments in Children with Chronic HBV
Dec. 17 - When the therapeutic efficacy of two different treatment regimens was studied, results showed that there was no substantial difference between sequential and simultaneous treatments of Interferon-á and Lamivudine in children with chronic HBV. Read Full Article.
Effect of Lamivudine and Adefovir on Preventing Hepatocellular Carcinoma
Dec. 10 - A recent study concluded that oral antiviral agents, such as Lamivudine and Adefovir, may reduce the incidence of HCC in patients with HBV-related liver cirrhosis. Read Full Article.
New Upper Limit Defined for Normal ALT in Adolescent Males
Dec. 10 - The new definition of normal adolescent ALT allows greater sensitivity in diagnosing early liver disease and targeting interventions that can be implemented to minimize future health-related morbidity. Read Full Article.
Canadians May be Denied Access to Effective New Hepatitis B Treatment
Dec. 10 - A new drug reimbursement recommendation to restrict access to Baraclude(Entecavir) may result in a significant proportion of patients having to use treatment that has largely been abandoned in the USA and Europe as substandard. Read Full Article.
Study: No Link Between Hepatitis B Shot and MS
Dec. 4 - There is no link between vaccination to protect against hepatitis B and the risk of developing multiple sclerosis (MS) in childhood, a new study finds. Read Full Article.
After Hepatitis Case, State Acts to Speed Alerts to Patients at Risk
Dec. 3 - A nearly three-year delay in informing patients of a Long Island doctor that his poor infection-control practices could have exposed them to hepatitis and HIV has prompted New York officials to propose a series of changes to better coordinate Health Department investigations. Read Full Article.
Preemptive Lamivudine Therapy Reduces Risk of Liver Disease Flares in Hepatitis B Patients Starting Cancer Chemotherapy
Dec. 3 - Study results have found that treating HBsAg positive patients with Lamivudine prior to undergoing chemotherapy reduces their risk of HBV reactivation, acute liver failure, and mortality. Read Full Article.
Long-Term Treatment Success with Pegasys Plus Ribavirin for Patients with HCV and HBV Co-Infection
Dec. 3 - Researchers have concluded that combination therapy with Pegasys plus Ribavirin appears to be safe and effective for treatment of patients co-infected infected with HCV and HBV with a substantial proportion of the patients achieving HBsAg clearance. Read Full Article.
Non-Invasive Tests for Cirrhosis May Help to Avoid Liver Biopsy
Dec. 3 - Ultrasound and magnetic resonance imaging techniques may reduce the need for biopsies and provide a useful new set of tools not only for diagnosing liver fibrosis and cirrhosis, but also for evaluating the effectiveness of new treatments for early-stage fibrosis. Read Full Article.
New Wave of Immigration Blamed for Doubling of HBV in UK
Nov. 26 - A recent report found that soaring rates of hepatitis B infection fuelled by large-scale immigration pose a serious health threat in the UK that is not being addressed properly. A public education campaign, universal vaccination policy, and action to identify and treat those who are infected were recommended. Read Full Article.
Growing Focus on Reused Medicine Vials
Nov. 26 - Public health officials have raised a red flag about the risks of transmitting blood-borne diseases through medicine vials that hold more than one dose. While such vials may reduce waste of medicine, they are more susceptible to contamination than single-dose vials. Read Full Article.
New Organ Allocation Criteria Associated with Decreased Deaths on Liver Transplant List
Nov. 26 - By changing the method in which donated livers are allocated to potential transplant patients, the number of deaths among individuals on the waiting list has decreased. Conclusive evidence has shown that this policy had a positive impact on waiting list mortality. Read Full Article.
First FDA-Approved Drug Therapy for Liver Cancer
Nov. 20 - The FDA has approved a New Drug Application for Nexavar, an oral anticancer drug shown to significantly improve overall survival in patients with liver cancer. This new drug provides a valuable option for liver cancer patients and will likely become the standard systemic therapy for treatment. Read Full Article.
Scientific Evidence of the Significant Anti-cancer Effect of Milk Thistle
Nov. 19 - Research results have indicated that silibinin, an active compound in milk thistle, can be used to prevent the development of liver cancer. Read Full Article.
Get Kids Vaccinated or Else, Parents Told
Nov. 16 - Prince Georges County, Maryland is threatening to take legal action against parents who do not get their children mandatory hepatitis B and chickenpox vaccinations. Read Full Article.
U.S. Representative Mike Honda Introduces Bi-Partisan Bill to Boost Hepatitis B Research and Prevention
Nov. 14 - Aiming to reduce the number of Hepatitis-B victims, Rep. Mike Honda (D-CA) and Rep. Charlie Dent (R-PA) recently introduced a bill that could boost immunization rates against the disease and increase funding for Hepatitis-B research. Read Bill H.R. 3944
Tenofovir Works for HBV-Infected Patients
Nov. 14 - Tenofovir is an effective and well-tolerated treatment option for HBV monoinfected patients with prior treatment experience, according to the findings of a recent study. Read Full Article.
Gender Difference in the Natural Course of HBeAg Positive Chronic Hepatitis B
Nov. 14 - Taiwanese researchers reported results from a longitudinal study to clarify gender-related differences in the natural history of hepatitis B, taking into account HBV genotype. Read Full Article.
Failure to Immunize Makes Britons Susceptible to Hepatitis B Infection
Nov. 13 - The failure of the UK to introduce universal hepatitis B immunization means that most British citizens are susceptible to infection, warns an infectious disease expert. Read Full Article.
Questionnaire Determines Current Level of Oncologists Awareness of Antiviral Prophylaxis to Prevent Reactivation of HBV
Nov. 13 - According to a recent survey, improving awareness of HBV reactivation and antiviral prophylaxis in the Oncology community appears warranted. Read Full Article.
NAC Slows Early-Stage Non-Acetaminophen-Related Liver Failure
Nov. 13 - There appears to be a benefit in administering the antidote for acetaminophen poisoning to slow early-stage acute liver failure triggered by hepatitis B and other causes. Read Full Article.
Cuba is Ready to Eradicate Hepatitis B
Nov. 8 - The increasing production of the Cuban vaccine Heberviovac HB has made it possible for the total elimination of hepatitis B, said Dr. Herrera during the inauguration of the 28th International Biotechnology Congress in Havana. Read Full Article.
Nationwide Decrease in the Need for Liver Transplant
Nov. 5 - A new Mayo Clinic study found a nationwide decrease in the need for liver transplant in patients with hepatitis B, which coincides with the increasingly widespread use of oral antiviral medications to slow disease progression. Read Full Article.
Merck to Develop HEPLISAV, an Investigational HBV Vaccine in Phase 3 Trials
Nov. 5 - Dynavax and Merck announced a global partnership to jointly develop HEPLISAV, a novel investigational hepatitis B vaccine, which shows promise great promise for hard-to-protect patient populations. It's in Phase 3 trials for older adults and dialysis patients. Read Full Article.
Ignorance fuelling spread of hepatitis B in Asia
Nov. 5 - Ignorance is fuelling the spread of hepatitis B in Asia, where patients are failing to get proper treatment and not enough is done to reduce transmission of the virus from mother to child. Read Full Article.
Favorable Prognosis Seen in Children with Chronic Hepatitis B
Oct. 29 - A report in the October issue of Clinical Infectious Diseases evaluates the clinical, biochemical, virological, and histological features of chronic hepatitis B virus infection and looks at data regarding its long-term course in children. Read Full Article.
New Theory of How Viruses May Contribute To Cancer
Oct. 29 - A new study suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits. Researchers call this the Phoenix Paradigm. Read Full Article.
Hepatitis B, Liver Cancer Hit Asian Community
Oct. 29 – Compared to other ethnicities, Asian Americans are nearly three times as likely to develop liver cancer, mostly due to the prevalence of chronic hepatitis B infection. Language barriers, lack of medical care access, and cultural taboos have been cited as reasons Asian Americans do not get the necessary screening for HBV and liver cancer. Read Full Article.
FDA Approves Alternate Dosing Schedule for a Twinrix
Oct. 22 - Twinrix, the only hepatitis A and hepatitis B combination vaccine available in the U.S has been approved by the FDA for an accelerated dosing schedule. This could benefit individuals who plan to travel internationally to high-risk areas, healthcare workers and emergency personnel, people who have been diagnosed with sexually transmitted diseases, as well as others at risk for hepatitis. Read Full Article.
Gilead Submits Marketing Applications for Viread for HBV
Oct. 22 - Data from clinical trials show that Viread (Tenofovir), currently approved to treat HIV, can have beneficial effects on chronic hepatitis B throughout the course of infection, potentially preventing fatal liver damage and liver cancer. Read Full Article.
Immune Cells Fighting Chronic Infections Become Progressively 'Exhausted'
Oct. 22 - A new study of immune cells battling chronic viral infection shows that the cells, called T cells, become exhausted by the fight and undergo profound changes that make them progressively less effective over time. Using a technique called gene-expression profiling, scientists have studied the mechanisms involved in T cell exhaustion. Read Full Article.
Use of Hepatitis B Vaccine for the Treatment of Chronic Hepatitis B
Oct. 16 - The HBV vaccine administered with interferon and nucleoside analogs may be a promising new therapeutic approach to control chronic Hepatitis B. The combination therapy is being evaluated for its efficacy and ability to suppress viral replication. Read Full Article.
Telbivudine May Be More Efficient for Chronic Hepatitis B
Oct. 16 - Data from this and previous studies indicate that Telbivudine may provide greater and more consistent HBV DNA suppression than Adefovir and Lamivudine in chronic hepatitis B e-antigen (HBeAg) positive patients. Read Full Article.
Minimal Hepatic Encephalopathy Associated With Increased Traffic Accidents
Oct. 16 - "Patients with cirrhosis who are not actively drinking should always be asked about their driving history," concludes study that shows patients with minimal hepatic encephalopathy report more traffic accidents and violations than other individuals. Read Full Article.
Noninvasive Tests for Cirrhosis May Help To Avoid Liver Biopsy
Oct. 8 - New non-invasive imaging techniques may provide an innovative set of tools not only for diagnosing liver fibrosis and cirrhosis, but also for evaluating the effectiveness of new treatments for early-stage fibrosis. Read Full Article.
Researchers Study Attitudes of Chronic Hepatitis B Patients in the USA
Oct. 8 - Researchers suggest that CHB patients experience greater symptoms than previously recognized and that patients perceptions of disease and attitudes about treatment may differ based on individual ethnicity and/or treatment experience. Read Full Article.
Stanford Researchers Find Way to Fight Treacherous Hepatitis B
Oct. 4 - One in four people who are chronically infected with hepatitis B will die from its impact if untreated, but a team of researchers at the Stanford University School of Medicine has identified the most cost-effective way of fighting this treacherous infection. Read Full Article.
World Hepatitis Awareness Day 2007
Oct. 1 - Events are taking place today in more than forty counties worldwide to increase awareness of viral hepatitis and encourage those who may be at risk to 'Get Tested'. Read Press Release.
Mixing Large Doses of Common Painkiller and Caffeine May Increase Risk of Liver Damage
Oct. 1 - Scientists have reported a potentially harmful interaction from consuming large amounts of caffeine while taking acetaminophen. They warn patients should monitor their intake carefully to prevent liver damage. Read Full Article.
Chronic Hepatitis Common in Children with HIV
Oct. 1 - A recent report found that all children and adolescents with HIV should be routinely screened for both hepatitis B and C. Read Full Article.
Favourable Outcomes for Long-term Lamivudine Treatment of Children with Chronic HBV
Sept. 27 - The aim of this study was to examine the safety of lamivudine and the durability of clinical responses in a group of children who received up to 3 years of treatment for CHB. Read Abstract.
Teesside Pupils Will be First for Hepatitis B Vaccine
Sept. 27 - Around 4,000 youngsters between the ages of 11 and 13 in the South Tees area of the U.K. will be vaccinated as health chiefs aim to catch up in tackling a national rise in infections. Read Full Article.
A Fruity Solution Against Hepatitis B?
Sept. 27 - New approaches are needed to succeed in bringing this virus under control - genetically modified plants may be a promising attempt. Dr. Xiao-Ming Lou and his team in Shanghai, China, modified the genome of a tomato in a way that the plant becomes an edible-vaccine, which will create a good immune response and be less expensive than the existing vaccines. Read Full Article.
Comparison of Same-Day Pre-Biopsy Versus Real-Time Ultrasound Approach
Sept. 27 - It is not clear as to whether performing real-time ultrasound (i.e. at the time of liver biopsy) is any more effective than marking the puncture site shortly before biopsy. Biopsy size, fragmentation, complications and diagnostic outcome were assessed in the comparison between approaches. Read Full Article.
Liver Cancer Marker Could Yield Blood Test for Early Detection
Sept. 19 - Researchers report on a new blood screening technique that could make it possible to detect early-stage liver cancer and predict how well a patient will do following treatment. Read Full Article
Pioneering New Treatment “Cooks” Liver Tumors
Sept. 19 - Cancer patients from across the world may benefit from an innovative treatment which destroys cancerous tissue and minimizes the chance of the disease reoccurring. Read Full Article.
Targeting Nerve Growth Factor May Lead To Cure For Liver Cancer
Sept. 19 – Scientists have discovered that Nerve Growth Factor plays a critical role in the development of liver cirrhosis and its progression towards hepatocellular carcinoma. In the future, bioengineers may be able to use NGF in the early diagnosis of liver cirrhosis and HCC. Read Full Article.
HCV and HBV Spreading More Slowly Among Injection Drug Users in San Francisco
Sept. 12 - Injection drug users are still at a very high risk of acquiring hepatitis C and B; however, needle-sharing is less common, and users do not become infected as quickly as they did in the past, according to a new study. Read Full Article
FDA Safety Warning: PegIntron
Sept. 12 - The FDA revised safety labeling for peginterferon alfa-2b to warn of the risk for potentially fatal psychiatric events. Extreme caution is therefore advised when treating patients with a history of psychiatric disorders. Read Full Article.
HBV Coinfection Linked to Reduced Efficacy of Anti-HCV Therapy
Sept. 12 – In patients chronically infected with hepatitis C, coinfection with hepatitis B appears to decrease the efficacy of anti-HCV therapies, regardless of the viral genotype, new research suggests. Read Full Article.
Third Annual Answer to Cancer Run Benefits Hepatitis B Foundation
Sunday Sept. 16, 2007 @ 9:00 am in Mahwah, NJ
Sept. 5 - Answer to Cancer, a national foundation that benefits organizations that promote awareness for hepatitis B and liver cancer, will hold its third annual 5K run/walk at Darlington Park in Mahwah, NJ, on Sunday, September 16. The A2C Foundation has raised more than $350,000 since its inception in 2003. Register Today!
China Has 120 Million Hepatitis B Carriers
Sept. 5 - At least 120 million people in China have become carriers of the hepatitis B virus out of the 700 million people who once were infected with it, announced the Chinese Ministry of Health at the unveiling of a free hepatitis B vaccination project for 320,000 primary school students in northwest China's Qinghai Province. Read Full Article.
Muscular Exercise Can Cause Highly Pathological Liver Function Tests in Healthy Men
Sept. 5 – A study in healthy men revealed that AST and ALT increased significantly after intensive muscular exercise (weightlifting) and remained increased for at least 7 days post-exercise. These findings highlight the importance of imposing restrictions on weightlifting prior to and during clinical studies, and that intensive muscular exercise should also be considered as a cause of asymptomatic elevations of liver function tests. Read Full Article.
Scientists Develop New Test for Liver Cancer
Aug. 21 - A simple blood test can detect early stage liver cancer and more accurately diagnose a disease that is a major killer in Asia and Africa. When used in conjunction with the [standard] AFP test, the new method was "more accurate and represents a more powerful tool to better detect liver cancer and save lives by getting patients earlier treatment", said researchers. Read Full Article.
Hepatitis B Virus and HIV Coinfection: Results of a Survey on Treatment Practices and Recommendations for Therapy
Aug. 21 - Inconsistencies among the different sets of guidelines for the treatment of HBV infection is a reflection of the complexities involved in treating such individuals. To address this important issue, a survey on how clinicians "in the real world" are managing HIV-HBV coinfected patients was sent to a federally funded, national network of community-based clinical treatment centers. Read Full Article.
An Editorial: Screening For and Treating Hepatitis B Virus in Patients with HIV Infection
Aug. 21 - Why it is so important to be diligent with regard to screening for hepatitis B virus (HBV) in the context of HIV infection? Treating HBV infection, if necessary, makes a difference . . . preventing HBV infection is better than treating it. Thus, every HIV-infected patient should be screened for HBV infection and offered vaccination in the instance of negative results for HBV markers. Read Full Article.
Progress in Hepatitis B Prevention Through Universal Infant Vaccination
Aug. 16 - China has made substantial progress in implementing universal, timely hepatitis B vaccination for infants, and preventing chronic HBV infection in children. Read Full Article.
Ignorance About Hep B Worries Charity
Aug. 16 - A recent poll conducted in the UK by the NHS Foundation Trust found that most gay men know little about Hepatitis B. The goal of the organization is to provide information and services about HBV to gay and bisexual men. Read Full Article.
Father-to-Child Hepatitis B Transmission Documented in Japan
Aug. 16 – Researchers in Japan found evidence of HBV infection via father-to-child transmission. Based on their findings, universal vaccination against HBV of all children was recommended. Read Full Article.
Hepatitis B Vaccine Protection May Not Be Long-Lasting
Aug.7 - Two adolescents in five who received a first dose of hepatitis B vaccine as newborns had evidence of waning immunity by age 14. Only 60% of 14-year-olds had an anamnestic response to hepatitis B vaccine booster dose compared with 97% of five-year-olds, according to findings published in the August issue of Pediatrics. Read Full Article.
5.4% of Healthy Blood Donors with the Core Antibody Have Detectable Viral Load
Aug. 7 - Transmission of HBV through blood transfusions is rare, but does occur even when donors test negative for the hepatitis B surface antigen (HBsAg), which is believed to be the hallmark of HBV infection. Read Full Article.
Coffee Consumption and Risk of Liver Cancer
Coffee, 2 Cups Daily, May Reduce Risk for Liver Disease, ALT Elevations
Aug. 7 – a meta-analysis of observational studies indicate that an increased coffee consumption is associated with a reduced risk of liver cancer, both among individuals with and without a history of liver disease. Overall, the risk of liver cancer decreased by 43% for an increment of 2 cups of coffee per day…A protective effect of coffee consumption on liver cancer is biologically plausible. Read Full Article.
Korean Mummy Holds Clues to Disease
July 26 – The liver of a child mummy preserved for 500 years will be studied by a team international experts to help scientists understand how the hepatitis B virus evolved to its present state and what to expect in the future. Read Full Article.
Protecting HIV Patients from Hepatitis B Virus
July 26 – Because individuals infected with HIV are at a significantly increased risk for contracting HBV, researchers at the University of Alberta endorse HBV immunization for this high-risk population and further studies to identify why some HIV patients fail to respond to the vaccine. Read Full Article.
Management of HBV Infection in Japan
July 26– In an effort to develop more efficient treatments for HBV, scientists at Kyoto University performed a pilot study of sequential therapy with lamivudine/interferon and found this protocol to be a viable alternative to conventional monotherapy. Read Full Article.
Does Race or Gender of HCV Patients Influence Physicians' Testing for Hepatitis A and Hepatitis B?
July 26 - A recent study revealed that a patients' race, but not gender, had a significant impact upon whether HCV-infected individuals were tested for HAV and HBV by their physicians. Read Full Article.
Researchers Develop Tool to Gauge Quality of Life of Hepatitis B Patients
July 18 – In a new study, UCLA researchers measured the effect of hepatitis B on patients' quality of life beyond just the physical symptoms of the disease and created a new tool to better assess patients' overall well-being, which may help clinicians guide treatment. The study documented that for those without advanced liver disease, the psychosocial impact of the disease affected their lives more than the physical symptoms. Read Full Article.
High-Risk Groups Told to have Blood Tested for Hepatitis
July 18– More than a million Malaysians are estimated to be carriers of hepatitis virus, and the Health Ministry wants those in the high-risk groups to have their blood tested. Read Full Article.
Infectious Diseases Experts Issue Blueprint To Avert Thousands Of Preventable Deaths
July 18 - The Infectious Diseases Society of America has released a new "Blueprint for Action" to increase adult vaccination rates against preventable deaths. The plan calls for raising public awareness about the importance of adult vaccination, improving access and affordability, and educating physicians to offer adult vaccinations during routine office visits. Read Full Article.
The HBV Asian Epidemic You Don't Know About
July 11– A press conference in New York City last month addressed an issue that often goes ignored but is already affecting many Asian Americans in the 21st century - chronic hepatitis B. A recent study revealed some alarming figures: survey responses of patients (55% of whom were Asian American) indicated that not enough patients or the general population are properly informed about hepatitis B and its causes, although the similarities to the HIV epidemic are obvious. Read Full Article.
Incidence of Non-Hodgkin's Lymphoma Among Individuals with Chronic Hepatitis B
July 11– Researchers reported in Hepatology this month that patients with chronic HBV infection were almost 3 times more likely to develop non-Hodgkin's lymphoma (NHL) compared with comparison patients, after adjusting for demographics, comorbidity, and HCV co-infection. Read Full Article.
Some 12 Million Vietnamese Suffer From Hepatitis B
July 11– Some 12 million Vietnamese people (or 14 percent of Vietnam's population) are infected with hepatitis B and up to 12 percent of the infected people are aged around 10 years. Approximately three million of them need treatment, reported China's Xinhua news agency. Read Full Article.
Over Half of Trainee Surgeons in U.S. Don't Report Needlestick Injuries
July 6 – According to a New England J. of Medicine study, nearly every trainee surgeon has experienced a needlestick injury by their final year of postgraduate education. Up to 800,000 needle-stick injuries are reported annually by healthcare workers in the US, but over 50% of all needlestick injuries are not reported, including 16% of injuries that involved a source patient who was infected with HIV, hepatitis B, or hepatitis C. Read Full Article.
Why Liver Cancer is More Prevalent in Males than in Females
July 6– Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer in men than in women, according to researchers. Liver cancer (or hepatocellular carcinoma- HCC) is a devastating complication of chronic inflammation caused by risk factors such as hepatitis B and C. Read Full Article.
New Data Suggest that Patients with Chronic Liver Disease are at Increased Risk for Heart Disease
July 6 - Researchers publish data that NASH, HCV, and HBV are strongly associated with early atherosclerosis (hardening of the arteries) independent of classical risk factors such as insulin resistance and metabolic syndrome components. Read Full Article.
Hepatitis B Drug Can Compromise HIV Treatment
June 29 – The United States Department of Health and Human Services now recommends against using entecavir (baraclude) as the first option in treating patients co-infected with hepatitis B and HIV. Researchers reported that a patient infected with both hepatitis B and HIV who was treated with entecavir developed a mutant strain of HIV that is resistant to other antiviral drugs. Read Full Article.
Abbott's RealTime Hepatitis B Viral Load Test Receives CE Marking in Europe
June 29– Abbott has received CE marking for a real-time PCR (polymerase chain reaction) test for monitoring hepatitis B viral load in patients, allowing the test to be marketed in the European Union. The RealTime HBV assay is a reliable test for detecting and measuring all known HBV genotypes; thereby, giving physicians better information to guide treatment decisions. Read Full Article.
Sci B Vac Proven to Prevent Recurrence of Hepatitis B
June 29 - Scigen Limited announced that Sci B Vac, a new hepatitis B vaccine derived from mammalian cells, has been proven to prevent recurrence of hepatitis B virus infection in patients receiving antiviral prohylaxis after liver transplantation for chronic hepatitis B. Read Full Article.
Viread Phase III Study for Chronic HBV Meets Primary Endpoint
June 21 – Viread (tenofovir DF) 300 mg met its primary efficacy endpoint: a complete response at week 48 defined by serum HBV DNA levels below 400 copies/mL and histologic improvement by at least a two point reduction. Read Full Article.
FDA Warns DuPont About RelyOn Claims of Prevention
June 21– DuPont was warned by the U.S. FDA about "misbranding" its RelyOn antiseptic spray and hand wipes, which has insufficient evidence to support its claims these products prevent diseases including hepatitis A, B, and C, and HIV type 1. Read Full Article.
In 'Spontaneous' Liver Cancer, Researcher Sees a Cure
June 21 - Researchers at Georgetown University have uncovered a new molecular mechanism that may “spontaneously” cause liver cancer. This finding could suggest a method to target pre-cancerous lesions in the liver.. Read Full Article.
NASTAD Releases Primer on Viral Hepatitis Policymaking and Programs
June 11 – A “Primer on Viral Hepatitis Policymaking and Programs at the Federal Level” has been released by the National Alliance of State & Territorial AIDS Directors (NASTAD) to increase understanding about the process through which federal viral hepatitis funding and program decisions are made. Access Article.
Prognosis Following Hepatitis B Surface Antigen Clearance
June 11– Clearance of hepatitis B surface antigen (HBsAg) remains the goal of antiviral therapy for chronic hepatitis B, but some research suggest that patients who clear HBsAg remain at risk for hepatic complications including liver cirrhosis and hepatocellular carcinoma (HCC). Read Full Article.
Liver Cancer Patients with High HBV Levels Face Poorer Outcomes
June 11 - Based on findings from the first-ever study examining the prognostic value of serum HBV DNA levels for patients with liver cancer undergoing chemotherapy, researchers recommend that antiviral therapies to reduce HBV viral load should be considered as part of management for liver cancer patients undergoing chemotherapy. Read Full Article.
Hepatitis B Patients' Understanding of Infection and Treatment Deficient
June 1 - Many patients with chronic hepatitis B are deficient in their understanding of the lifelong disease and often do not comply with the drug regimens necessary to control it, according to a new UCLA survey that suggests improved patient involvement in disease management decisions could be the key to fixing this problem. Read Full Article.
Toward A Banana-Based Vaccine For Hepatitis B
June 1 - Bananas have emerged as the best candidate to deliver a bite-sized vaccine for hepatitis B virus (HBV) to millions of people in developing countries, according to researchers. Read Full Article.
Prevention of Hepatitis B in Travelers
June 1 – Foreign travel is increasing and many travelers are at risk of developing hepatitis B. A prevention guide for health professionals gives useful advice to all travelers. Read Full Article.
HBV Not Directly Tied to Increased Stroke Risk
May 23 - The increased risk of stroke or myocardial infarction (MI or heart attack) associated with hepatitis B appears to be secondary to liver dysfunction rather than a direct consequence of HBV infection, Korean and UK researchers report in the May issue of Stroke. Read Full Article.
Asians Losing Race with Hepatitis
May 23 - As an Asian-American politician, Chi Mui became San Gabriel's first Asian mayor in March 2006. As an Asian, Mui belonged to a larger, more disturbing health care demographic. He died of liver cancer at 53 after about a month in the position. Mui had hepatitis B, a disease that is dubbed a "silent killer" and disproportionately affects Asians. Read Full Article.
Causes of Death in Individuals with Hepatitis B or C
May 23 – A large study was conducted over 12 years to investigate all causes of death among individuals with HBV and/or HCV in a community-based setting. Researchers concluded that, “Our data highlight that young people with hepatitis C and with HBV/HCV coinfection face a higher mortality risk from continued drug use than from their infection, whereas the main cause of hepatitis B death was liver related.” Read Full Article.
May 2007 is 12th Annual Hepatitis Awareness Month
May 15 - May 2007 marks the 12th anniversary of Hepatitis Awareness Month. The May 11 issue of MMWR highlights public health measures to vaccinate and protect children from hepatitis B virus infection in China and to monitor the characteristics of persons with chronic hepatitis B in San Francisco, California.
Read Full Article.
Characteristics of Persons with Chronic Hepatitis B --- San Francisco, California, 2006
May 15 - In 2006, the San Francisco Department of Public Health characterized persons with reported confirmed chronic HBV infection for a hepatitis B registry, which will enable health departments and health-care providers to link HBV-infected persons and their contacts with recommended prevention and care services.
Read Full Article.
Revised Treatment Guidelines for Use of Entecavir in HIV-HBV Co-Infected Patients
May 15 - The U.S. Department of Health and Human Services released a supplement to their guidelines HIV-1-infected adults and adolescents concerning use of entecavir (Baraclude) in HIV-HBV coinfection. This revision was made in response to recent reports indicating that entecavir may be active against HIV as well as HBV, and thus could promote the development of drug-resistant HIV if used as monotherapy. Read Full Article.
Prevention of Hepatitis B in Travelers
May 15 - Foreign travel is increasing and many travelers are at risk of developing hepatitis B. A prevention guide developed for health professionals to give advice to travelers is also useful for the general public
Read Full Article.
U.S. Representatives Recognize National Hepatitis B Awareness Week!
May 9 - In order to break the silence surrounding this deadly disease and bring awareness to the American people, Rep. Mike Honda, Rep. Edolphus Towns, and Rep. Charlie Dent introduced H. Res. 366, Supporting the Goals and Ideals of National Hepatitis B Awareness Week.
Read Full Article.
Wednesday May 9 @ 12 Noon - Free Webcast: The Changing Epidemiology of Hepatitis B
May 9 - An online audio webcast featuring Dr. Stanley Martin Cohen, Associate Professor of Medicine and Director of Hepatology at Rush University Medical Center, Chicago, IL, will be offered for 1 CEU. The webcast is offered by Abbott Diagnostics in collaboration with the Hepatitis B Foundation. Free Online Registration Now!
Nucleonics Receives FDA Clearance to Begin Phase 1 Trial of New eiRNA Therapy for HBV
May 4 -The U.S. Food and Drug Administration has approved Phase I human clinical trials for Nucleonics’ investigational eiRNA therapy for the treatment of chronic hepatitis B, which will begin in June. Read Full Article.
Woman Contracts Hepatitis B During Oral Surgery
May 4 – Universal hepatitis B vaccination of all adults up to 40 years of age should be encouraged according to New York City officials who report the hepatitis B virus was transmitted from one patient to another when they both underwent oral surgery in the same office on the same day, despite proper infection control measures. Read Full Article.
Does Exposure to Hepatitis B Increase Risk for Liver Cancer in HCV Patients?
May 4 – Researchers reported results from a 10 years study of HCV patients that show exposure to HBV increases the risk for liver cancer in patients with HCV infection and cirrhosis. Read Full Article.
Blood DNA Can Be Early Predictor of Liver Cancer
April 25 – Scientists have discovered a means for early detection of liver cancer using DNA isolated from serum samples as a baseline biomarker. This is a critical breakthrough for identifying hepatocellular carcinoma (HCC) at an earlier stage. Read Full Article.
Prolonged Antiviral Therapy for Hepatitis B Virus-Infected Health Care
April 25 – Prolonged antiviral therapy has been found to be a viable management option to prevent transmission of the HBV virus from healthcare workers to patients. Read Full Article.
Pegintron Approved in China for Treating Chronic Hepatitis B
April 25 – Schering-Plough Corporation has announced that PEGINTRON (peginterferon alfa-2b) has been approved by the Chinese State Food and Drug Administration for the treatment of patients with chronic hepatitis B, the most prevalent infectious disease in China and one of the country's leading causes of death. Read Full Article.
Hepatocellular Carcinoma Does Not Decrease Liver Transplant Survival
April 18 – A recent comparison of survival in hepatitis B patients undergoing liver transplantation for cirrhosis vs. hepatocellular carcinoma shows rates are comparable: 90% vs. 83% respectively. Read Full Article.
Standard Tests May Not Detect "Hidden" Hepatitis B in HIV/HBV Coinfected Patients
April 18 – A significant number of HIV patients may have "occult" (or hidden) HBV infections that are not detected with standard screening tests, according to two recent studies. These results indicate a need for better screening for HBV in "high-risk" populations. Read Full Article.
Antiviral Therapy for Hep B Health Workers Reduces Work Restrictions
April 18 – Providing antiviral therapy for HBV infected health care workers prevents the loss of highly qualified medical personnel without jeopardizing patient safety, finds researchers. Read Full Article.
Watch Out for Hepatitis B
April 12 – Only half the HIV patients attending U.S. clinics are being monitored for hepatitis B, according to three recent studies. Since between 1 in 4 and 1 in 10 patients who have hepatitis B may have an 'occult' infection, meaning the virus cannot be detected with standard blood tests, there is a greater need to test HIV patients for a possible co-infection with HBV. Read Full Article.
FDA Licenses First Biologic Product to Prevent HBV Reinfection in Liver Transplant Patients
April 12 – HepaGam B is the first immune globulin product to be approved for the prevention of HBV reinfection in liver transplant patients. This approval provides a new treatment option for transplant patients who are at increased risk of reinfection of HBV. Read Full Article.
Two Studies Examine Effect of Age on Liver Disease Progression
April 12 – Patients who experience HBeAG seroconversion before age 40 are at a significantly lower risk of progression to liver cirrhosis than those over age 40. Also, researchers studying the relationship between age and development of hepatocellular carcinoma (HCC) found that the development of HBV-related HCC in young patients may be different from their older counterparts. Read Full Article.
High-Tech Tools Fight Hepatitis
April 5 – In an effort to bring healthcare to the community, clinics in Hawaii plan to use telemedicine in the treatment of hepatitis. With the use of a video monitor and audio system, doctors hope to bring medical care to the needy or homeless in rural areas Hawaii. Read Full Article.
FDA Approves Accelerated Dosing Schedule for Twinrix
April 5 – Twinrex, the only hepatitis A and hepatitis B combination vaccine available in the U.S has been approved by the FDA for an accelerated dosing schedule. This could benefit individuals who plan to travel internationally to high-risk areas, healthcare workers and emergency personnel, people who have been diagnosed with sexually transmitted diseases, as well as others at risk for hepatitis. Read Full Article.
Rare Case of Dental Patient-to-Patient Hepatitis B Virus Transmission Recorded
April 5 – Researchers have documented a case of hepatitis B virus transmission between two patients at a dentist's office in the U.S. While this kind of infection is exceedingly rare, universal vaccination against the virus would likely have prevented both cases. Read Full Article.
PKIDS Interviews Dr. Timothy Block, Co-Founder of the Hepatitis B Foundation
March 27 – The national nonprofit PKIDS interviews Dr. Timothy Block, Co-Founder and President of the Hepatitis B Foundation, a world-class nonprofit research organization with a mission to find a cure and improve the lives of 400 million people living with this serious liver disease. Download Podcast Interview.
America's Scientific and Medical Progress Threatened By Flat Funding For NIH
March 27 – Leading U.S. universities call for increased NIH funding to protect health and retain the nation's scientists. The report argues that research momentum gains have slowed, and in some cases may be lost, if flat funding continues. Read Full Article.
FDA Warns Against Use of Emtricitabine (Emtriva) with Duplicate Combination Products and Lamivudine
March 27 – FDA Warns Against co-administration of emtricitabine with other emtricitabine-containing products and lamivudine. This includes fixed-dose combination products with emtricitabine or lamivudine. Read Full Article.
2-For-1 Liver Transplant Saves Two
March 20 – Transplant surgeons split one liver between two patients with success. It doesn't happen often with the more than 6,000 liver transplants annually. Just 123 split-liver transplants were performed in the U.S. last year. If more were performed, there would a much shorter waiting list for liver transplants. Read Full Article.
Police, Fire and Prison Staff to Get Injections Against Hepatitis B
March 20 – Police and firefighters will be given the hepatitis B vaccine as part of a number of new measures to protect frontline workers from blood-borne viruses. Read Full Article.
Hepatitis A and Hepatitis B at Lowest Levels Ever Reported
March 15 – CDC reports that hepatitis A and B are at the lowest levels ever in the United States due to safe vaccines and strong federally support immunization programs. Read Full Article.
Sport Fears Over Sweat Risk
March 12 – A recent study of 70 male Olympic wrestlers found eight who had the hepatitis B virus in their sweat. However, British experts say that catching it through sweat, rather than blood, remains extremely unlikely. Read Full Article.
Hepatitis B Vaccination for Iranian Teens Starts
March 12 – Nationwide hepatitis B vaccination for Iranian teens has started because hepatitis B is the leading cause of cirrhosis in the country and 2 million Iranians are chronically infected with the virus. Read Full Article.
Hepatitis E Vaccine Effective in High-Risk Population
March 12 – A new vaccine has been found to be more than 95% effective in preventing hepatitis E, which is transmitted through contaminated water and food. in healthy subjects from the Nepalese army. Read Full Article.
Hepatitis B Found in Sweat of Olympic Athletes
March 2 – A study conducted among 70 male Olympic wrestlers show that while none tested positive for hepatitis B, DNA testing found the virus hiding in the blood of 13% and in the sweat of 11%, with sweat levels of the virus similar to those found in the blood samples. Read Full Article.
Hepatitis B Drug Triggers HIV Drug Resistance
March 2 – A commonly used hepatitis drug spurs resistance to HIV drugs in patients who are infected with both viruses, Johns Hopkins researchers report. Read Full Article.
Sebivo (Telbivudine) Recommended for Approval in European Union for HBV
March 2 – An estimated one million Europeans are infected with hepatitis each year. A new drug, Sebivo, has been recommend for approval in Europe, which follows earlier approval in the U.S. where the drug is marketed as Tyzeka. Read Full Article.
Israeli Researchers Discover Drug Effective Against Liver Cancer & HBV
Feb. 27 – Pre-clinical studies from Can-Fite BioPharma, an Israeli biotech company, show that a drug that they are testing (CF102) is active not only against liver cancer but also hepatitis B. Read Full Article.
Romania Suffering Europe's Highest Hepatitis Rate
Feb. 27 – With 2 million of its 22 million people infected with a form of hepatitis, Romania has Europe's highest burden of the disease. Read Full Article.
Number of People Infected with Hepatitis B Reaches 4 Million in Turkey
Feb. 20 – With an estimated 4 million people in Turkey already infected with hepatitis B, the Health Ministry has plans for decreasing the rate by 2010. Read Full Article.
World Digestive Health Day – Focus: Hepatitis B and C
Feb. 20 – A total of 400 million people are chronically infected with hepatitis B, and about half that number is chronically infected with hepatitis C. Together, these diseases are responsible for the majority of liver cancer cases, the 3rd leading cause of cancer death worldwide. On May 29 2007, the World Gastroenterology Organisation (WGO) will focus worldwide attention on Hepatitis B and C during its World Digestive Health Day on May 29, 2007. Read Full Article.
Chinese Employers Shun Carriers of Hepatitis B
Feb. 20 – Discrimination against those with hepatitis B, experts say, is on the increase, partly because the dangers of the virus have been exaggerated by medical testing companies touting services and advertisers pushing fake cures. Such ploys gain attention in China, where 120 million carry the hepatitis B virus. Read Full Article.
Long-Term Adefovir Therapy Useful for Chronic Hepatitis B
Feb. 14, 2007 – New research shows that treatment with adefovir dipivoxil for up to 5 years is well tolerated and benefits hepatitis B patients who are e-antigen negative(HBeAg-). Read Full Article.
HBV Infection May Promote HCV Clearance in HIV Positive Patients
Feb. 14 – Researchers report that HBV may favor the elimination of HCV in HIV-coinfected patients, which may influence liver disease and therapeutic decisions. Read Full Article.
Superior Results Using Antiviral Agents Before Pegylated Interferon to Treat HBV
Feb. 6 - Studies have shown that using a potent antiviral before adding an immunomodulator (e.g. pegylated interferon) is a novel approach for improving the effectiveness of HBV treatment, and would also reduce the frequency of antiviral resistance. Read Full Article.
Management of HIV and Hepatitis B Coinfection
Feb. 6 - Coinfection with HIV and HBV has a significant impact on hepatitis B disease with faster rates of progression to cirrhosis and end stage liver disease. A recent review highlights the most important developments in the management of HIV and HBV coinfection. Read Full Article.
Complementary and Alternative Medicine in Hepatology
Feb. 6 – A review of the effectiveness of the use of complementary and alternative medicines among individuals with liver disease appears in the online edition of Clinical Gastroenterology and Hepatology. Read Full Article.
Transplant Shows Best Survival for Primary Liver Cancer
Jan. 23 - If all things were equal, a new liver would offer the best chance of long term survival for hepatocellular carcinoma. After five years, the survival rate for transplant patients was 67%, versus 38% for those who had surgical resection and 19% for ablation procedures. Patients with liver cancer who had no treatment have a five-year survival rate of 3%. Read Full Article.
Impact of Co-Infection with More than One Hepatitis Virus
Jan. 23 - Due to overlapping risk factors, many individuals are infected with more than one form of viral hepatitis. Since co-infections can cause more liver damage and complicate treatment, it is important that a person with one type of hepatitis be tested for other hepatitis viruses. Read Full Article.
Breakthrough Could Prevent Many Fibrotic Diseases
Jan. 23 - Researchers at Rice University have found that a protein, called serum amyloid P or SAP, could lead to the first treatment that prevents the build-up of deadly scar tissue in many diseases that account for an estimated 45% of U.S. deaths each year. Currently there are no approved treatments to prevent fibrosis (which occursin cirrhosis) and it is considered to be an irreversible process. Read Full Article.
Number of Hepatitis B Cases Rises Dramatically
Jan. 18 - New statistics indicate an enormous increase of hepatitis B in Ireland – from about 30 cases reported in 1997 to over 900 in 2005. Read Full Article.
Cancer Deaths Inch Down for Second Year
Jan. 18 – For the second year in a row, the absolute number of deaths caused by cancer have decreased in the U.S. Liver cancer, however, continues to be on the rise. Read Full Article.
Diabetics at Risk of Hepatitis B Due To Bad Medical Practices
Jan. 10 - Diabetic residents in nursing and care homes in the U.K. may be at increased risk of contracting hepatitis B because some staff continue to re-use disposable lancing devices that should only be used once. Read Full Article.
Parents in China Drop HBV Discrimination Suit
Jan. 10 - Parents of seven HBV-infected children recently expelled by a top school in China sued authorities for discrimination, but dropped their suits after heavy pressure from local officials. Read Full Article.
Diet Seen to Affect Hepatocellular Cancer Risk
Jan. 10 - Certain foods, among them milk and fruit, appear to reduce the risk of hepatocellular carcinoma (HCC), according to Italian researchers. Read Full Article.
Tenofovir Plus Emtricitabine Shows Efficacy in Resistant HBV Infection
Jan. 10 – A recent study indicates that tenofovir, after treatment failure with adefovir, may be an effective option for patients with resistant HBV infection. Read Full Article.
A Painkiller Reminder
Jan. 2 - FDA label proposal reinforces advice to proceed with caution on over-the-counter painkillers, noting they pose a risk of liver and stomach damage. Read Full Article.
Development of Osteoporosis in Liver Cirrhosis
Jan. 2 - Cirrhosis is a major cause of osteoporosis and its degree is related to the severity and not the cause of the liver disease. Read Full Article.
Clues to the Hepatitis Mystery
Jan. 2 - Thirteen centuries ago, Pope Zacharias quarantined jaundiced patients to stop liver sickness from spreading through Rome. But it took centuries before a team of scientists discovered the cause of infection. Read Full Article.
A Case for Treating High HBV DNA Levels Before Starting HIV Therapy
December 15 – Researchers make a case for providing hepatitis B treatment for co-infected patients with high HBV viral loads before initiating antiretroviral therapy for HIV. Read Full Article.
Updated HBV Immunization Recommendations for Adults
December 15 - Updated recommendations to increase hepatitis B vaccination of adults at risk for HBV infection in all settings have been published in the second of a two-part statement from the Advisory Committee on Immunization Practices. Read Full Article.
Factors Influencing Liver Disease Progression in Chronic Hepatitis B
December 15 – A new comprehensive review highlights pertinent data on the factors associated with progressive HBV-related liver disease in affected patients, which could lead to improvements in the selection of candidates for intervention, such as lifestyle changes and antiviral therapy, and overall disease management. Read Full Article.
Dynavax's HEPLISAV Vaccine Superior to Conventional HBV Vaccines
Nov. 28 - Dynavax Technologies announced that HEPLISAV, its HBV vaccine, can generate 98.5% protection after two doses in older difficult-to-immunize adults vs. 73.1% for Engerix-B by GlaxoSmithKline. Read Full Article.
School Nurses Working to Meet State Vaccination Requirements
Nov. 28 - State requirements that children get vaccinated for hepatitis B and chicken pox have many school systems scrambling to keep their children in class. Read Full Article.
Updated Management Guidelines for HBV in the Asia-Pacific
Nov. 28 - The ACT-HBV Asia-Pacific Steering Committee members have updated the treatment recommendations for chronic hepatitis B based on a review of the most recent clinical data in this highly endemic region of the world. Read Full Article.
HBV Advocate’s AASLD Conference Coverage
Nov. 28 – A list of all the important and interesting abstracts about hepatitis B from the 2006 AASLD Conference has been posted on the HBV Advocate website. Read Full Article.
NCI Researchers Induce Natural Killer Cells to Fight Liver Cancer in Mice
Nov. 21 - Two types of killer immune cells play divergent roles in fighting cancer located in the liver and study results provide insight into how the power of the immune system can be harnessed to develop new anticancer therapies. Read Full Article.
Model May Help Predict Survival After Liver Transplant
Nov. 21 - A new model may help predict survival after liver transplant and may be particularly helpful for expanding criteria to include marginal or high-risk donors; thus, increasing the availability of livers for transplantation. Read Full Article.
Superheroes Help Gay Community Fight
Nov. 21 - The "Vaccinators”, the sexual health superheroes, have rolled into town to encourage gay men in the United Kingdom to be vaccinated against hepatitis B. Read Full Article.
Can Green Tea Help
Ameliorate Liver Fibrosis?
Nov. 15 - Patients with chronic hepatitis often use alternative and complementary therapies they hope will improve liver health. According to researchers, green tea polyphenols may be a useful therapeutic agent for treatment of hepatic fibrosis. Read Full Article.
HBV Viral Load &
Nov. 15 - Persons with chronic hepatitis B have a significantly higher risk of mortality compared to uninfected persons which can be directly related to the amount of HBV viral load. Read Full Article.
Issues in Infectious Diseases
Nov. 15 - As International adoptions become increasingly common in the US, it is necessary for families considering adoption to become informed about potential infectious disease risks.Read Full Article.
Elevated ALT Levels Predict Risk of Death From Liver Cancer
Nov. 6 - The currently accepted upper limit of normal for ALT levels is "artificially high," officials from the AASLD believe. The current normal range excludes a number of individuals who feel well but who are at increased risk for liver disease. Read Full Article.
Hepatitis B in Children: Update 2006
Nov. 6 - HBV infection occurs in newborns, infants and children and is frequently unrecognized. Compared to the disease in adults, hepatitis B in children is frequently less severe but more likely to be prolonged. Read Full Article.
Three-Year Data Showed Low Incidence of Baraclude (Entecavir) Resistance in Nucleoside-Naïve Chronic Hepatitis B Patients
Nov. 6 - Bristol-Myers Squibb announced three-year results of the Baraclude (entecavir) resistance monitoring program, which found the incidence of resistance to be low among nucleoside-naïve patients treated with the approved drug. Read Full Article.
Tyzeka Bests Epivir at HBV Control at Two Years
Oct. 31- Tyzeka (telbivudine) was superior to Epivir (lamivudine) at reducing hepatitis B virus to undetectable levels report scientists at the October AASLD Meeting. Read Full Article.
British Scientists Grow Human Liver in a Laboratory
Oct. 31 - Scientists have grown the world's first artificial liver from stem cells in a breakthrough that will one day provide entire organs for transplant. Read Full Article.
The Hepatitis B Therapeutics Market in China Will Double by 2010
Oct. 31 - A leading research firm reports that China, the world's largest HBV drug market is expected to double by 2010 due to expanded diagnoses and treatment initiatives. Read Full Article.
Telbivudine Approved by FDA as New Treatment for Chronic Hepatitis B
Oct. 25 - Idenix Pharmaceuticals announced the approval of Tyzeka (telbivudine) by the U.S. Food and Drug Administration as a new once-a-day oral treatment, taken with or without food, for patients with chronic hepatitis B. Read Full Article.
Vaccination Nearly Eliminates HBV in Hawaiian Children
Oct 24 - Hepatitis B virus infections among elementary school children in Hawaii fell by more than 90% after universal infant hepatitis B vaccination was implemented, according to a report in the October issue of Pediatrics. Read Full Article.
Genetically Modified Viruses May Help Cure Hepatitis B Infections
Oct. 24 - South African scientists have developed a new approach using RNA interference (RNAi) technology that could potentially lead to a powerful medicine to treat the Hepatitis B. Read Full Article.
Some Prescriptions Can Lead to Chronic Drug-Induced Liver Injury
Oct. 24 - A new consortium study found higher rates of chronic drug-induced liver injury (DILI) resulting from common prescription medications. Read Full Article.
Schools Ban Hepatitis B Virus Carriers
Oct. 17– Nineteen junior high school students were told to leave school and go home after they were found to be carriers of the hepatitis B virus. The Chinese Ministry of Health blasted the decision to ban the pupils since it has launched a nationwide campaign calling on people to not take a biased attitude towards people with hepatitis B. Read Full Article.
CDC Announces Updates to the Adult Immunization Schedule
Oct. 17 - The Centers for Disease Control and Prevention (CDC) has expanded the Adult Immunization Recommendations, now available in English and Spanish, to include vaccination for any adult seeking protection from hepatitis B. Read Full Article.
Clinical Care Options Hepatitis 2006 Update
Oct. 17– CME programs are now available to assist physicians treating hepatitis B patients - an “Update on the Management of Hepatitis B”, by Mark Ghany, MD, and “HBV Resistance”, by Anna Lok, MD. Read Full Story.
Clinical Significance of Occult HBV in People with HIV
Oct. 10 - Some research has shown that coinfection with HIV and hepatitis B is associated with worse liver disease progression, but it is unclear with low levels of occult or "hidden" HBV. “Occult infection” is diagnosed when HBV DNA is detected with core antibodies (anti-HBc) but without surface antigen (HBsAg). Read Full Article.
Overview of Antiretroviral Therapy for Patients with HIV-HBV Coinfection
Oct. 10 - In the U.S. and Europe, it is estimated that 7%-10% of HIV positive men have chronic hepatitis B. "HIV infection modifies the course of HBV infection by increasing rates of chronicity, prolonging HBV viremia, and increasing liver-related morbidity," say researchers from Stanford University. Read Full Article.
Cost Effectiveness of Treatment Options for HBV Patients with Cirrhosis
Oct. 10 - Patients with chronic HBV are at risk for developing advanced liver disease, including cirrhosis and liver cancer. "Both entecavir and adefovir [monotherapy] are cost-effective" in patients with HBV-related cirrhosis, researchers concluded. Read Full Article.
Can Razor Blades Transmit Hepatitis B Virus?
Oct. 4- HBV is known to be transmitted through sharing drug-injection equipment, however, the risk of sharing of personal care items is less certain. Turkish researchers concluded from a recent study that reuse of blades that carry HBV can infect others. Read Full Article.
Women Given Liver Transplants Outlive Male Recipients By Around 4 Years
Oct. 4 - Researchers evaluated 2702 people who had received a liver transplant between 1985-2003, and found female liver transplant recipients outlive men given the same procedure by an average of 4.5 years. Read Full Article.
Chinese Doctors Urge Better Awareness of Hepatitis B Disease
Oct. 4– More than 300,000 Chinese died of liver cancer and cirrhosis due to hepatitis B, which is raising the alarm in China. It’s estimated that 120 million Chinese have hepatitis B, so the country has recently stepped up the efforts to raise public awareness of the disease. Read Full Article.
Idenix Gets OK for Chronic Hepatitis B Drug in Switzerland
Sept. 26 - Idenix Pharmaceuticals reports that Switzerland has approved its drug, telbivudine, for chronic hepatitis B in patients. A new drug application was submitted by Idenix with the U.S. Food and Drug Administration in late 2005. Read Full Article.
Sir Bob Geldof and World Health Organization Urge People At Risk to Get Tested for Hepatitis
Sept. 26 - Sir Bob Geldof adds his voice to that of hepatitis patient groups, the World Health Organization and the European Association for the Study of the Liver by calling on governments around the world to make hepatitis a priority before it’s too late. Read Full Article.
Regenerating Hope for Liver Disease
Sept. 26 - A protein, caveolin-1, was identified by scientists as being essential in the process of liver regeneration, in a discovery that could lead to treatments for serious liver diseases such as hepatitis. Read Full Article.
Cancer Death Rates on the Decline – Liver Cancer Rates Continue to Rise
Sept. 15 - Americans' risk of dying from cancer continues to edge down, largely because less people smoke, but the rate of new cases of liver cancer continues to increase, according to a report from the nation's leading cancer organizations. Read Full Article.
New Test for Acetaminophen Poisoning
Sept. 15 - A new test for acetaminophen poisoning, the most common cause of acute liver failure in adults in the United States is effective with children as well as adults, according to a study published in the September issue of the journal of the American Academy of Pediatrics. Read Full Article.
Grand Opening Celebration of the
Hepatitis B Foundation's New Biotech Center
Sept. 7 – More than 150 VIP guests and state legislators attended the Grand Opening of the new "Pennsylvania Biotechnology Center of Bucks County" held on Sept. 7, 2006. The Center was created by the Hepatitis B Foundation, and is owned in partnership with Delaware Valley College.
- At the opening, a congratulatory message from Pennsylvania Governor Edward Rendell was read by his representative. Read Full Letter.
- In addition, Governor Rendell announced the approval of the new biotech center as a Keystone Innovation Zone, which includes $250,000 in operational funds. Read Full Article.
- The Philadelphia Business Journal featured the dream, the mission, and the person who drove the creation of this new center. Read the Full Article.
Past HBV Viral Load Strong Predictor of Mortality and Morbidity from HCC and Chronic Liver Disease in a Prospective Study
Sept. 6– Researchers report the results of an 11-year study of almost 3,000 HBV-positive Chinese adults from Haimen City. High viral load is a strong predictor of mortality from liver cancer and chronic liver disease; past viral loads predict current liver disease severity; and viral load is useful in determining risk level in HBV. Read Full Article.
HBV Vaccine - A Success Story for Cuban Biotech Company
Sept. 6- Since 1999 there haven't been any cases of hepatitis B among Cuban children. All Cuban citizens born after 1980 received the HBV vaccine, produced by the Centre for Genetic Engineering and Biotechnology, and certified in 2001 by the World Health Organization. Read Full Article.
Updated: Hepatitis B and the Healthcare Worker
Aug. 30– Significant revisions to the educational Q&A “Hepatitis B and the Healthcare Worker”, created by IAC and reviewed by the CDC, should be read by all health professionals at risk or already chronically infected with HBV. Read Full Article.
Promising Alternative to Biopsy in Chronic Liver Disease
Aug. 30– The prognosis of chronic liver disease is directly related to the development of fibrosis. A simple, safe and non-invasive alternative method, transient elastography, seems to be one of the most promising and appears reliable for evaluating the stage of liver fibrosis. Read Full Article.
Vaccination Update Against Hepatitis B Virus in Patients with Chronic Kidney Disease
Aug. 30– Outbreaks of HBV infection among hemodialysis patients continue to occur despite vaccination. Researchers report that the route of vaccine administration appears to make a difference - giving the vaccine in the skin (intradermal) is associated with greater protection than when it is given in the muscle (intramuscular). Read Full Article.
Impact of “Hidden” HBV Infection in HIV patients Starting Antiretroviral Therapy
August 14– Hidden or “occult” HBV infection seems to be relatively frequent in HIV-positive patients starting drug therapy and may induce hepatic flares, even while on lamivudine treatment or when the drug is discontinued. Read Full Article.
Clinicians Expect Baraclude Use to Increase for the Treatment of HBV
August 14– A leading pharmaceutical market research firm finds that after one year on the market, more than 25% of clinicians surveyed say they prescribe Bristol-Myers Squibb's Baraclude (entecavir) as a first-line therapy for the treatment of hepatitis B and that they expect that its usage will increase in the next two to three years. Read Full Article.
Risk of New-Onset Hepatitis B in Patients Undergoing Chemotherapy
August 14 - Use of certain chemotherapy drugs weakens the immune system and can allow the activation or reactivation of HBV. New-onset hepatitis B after chemotherapy, which may be due to “hidden” or occult HBV infection, is associated with high rates of morbidity and mortality. Read Full Article.
New Updated Treatment Algorithm for Chronic HBV
Aug. 8– The U.S. Treatment Algorithm for HBV (Keeffe, et al), first published in 2004, has been updated to include data from two additional therapies, entecavir and peg-interferon, which were approved in 2005. There are now five approved HBV therapies. Read Full Article.
Age Alone Does Not Affect Outcome of Liver Transplant in Elderly
Aug. 8- Patients aged 70 years or older receiving liver transplants have the same survival rates as patients in their 50s, a new study shows. Therefore, elderly patients with liver disease should not necessarily be excluded from liver transplantation because of age alone. Read Full Article.
Cost Comparison of Hepatitis B Drug Therapy
Aug. 1– What does it cost for the different approved HBV drug therapies? See the cost comparison of the approved therapies provided in the Hepatitis B Foundation’s free B Informed newsletter. Read Full Article.
Donations after Cardiac Death Could Expand Organ Pool
Aug. 1 - Transplanting organs from those who suffer cardiac death, rather than the widely accepted standard of brain death, could sharply increase the supply by perhaps 25%. Read Full Article.
China Vaccinates 11 Million Children Anti-Hepatitis B Project
Aug. 1 - China has vaccinated more than 11 million children against hepatitis B since 2002, especially infants within 24 hours of birth to prevent maternal transmission. More than 120 million Chinese are chronically infected with hepatitis B, and the vaccination program is believed to have prevented some 200,000 future deaths from liver cancer. Read Full Article.
FDA Panel Advises Approval of Nabi-HB Drug
July 18– A Food and Drug Administration (FDA) advisory committee voted to recommend the use of Nabi- HB Intravenous (Hepatitis B Immune Globulin) to prevent recurrence of hepatitis B in patients who have received liver transplants, which paves the way for full FDA approval. Read Full Article.
More Kids Need Proof of Vaccines
July 18– This coming school year, for the first time, Maryland students in grades 5 through 9 must provide proof that they have been vaccinated against chickenpox and hepatitis B. State lawmakers ordered the change primarily to protect older children against hepatitis, a rising public health concern, as they approach adulthood. Read Full Article.
What You Should Know About Complementary and Alternative Medicine
July 18– There are important distinctions between complementary and alternative medicine. Complementary medicine is something that is used in conjunction with conventional medicine, while alternative medicine is used in place of conventional treatment. Read Full Article.
Hepatoxicity Warning Added to Ketek Label
July 7- The FDA has approved a label revision for the antibiotic Ketek (telithromycin) warning of possible severe and sometimes fatal liver injury during or immediately following treatment with the drug that is used for respiratory conditions. Read Full Article.
High Tylenol Doses Linked To Liver Woes
July 7- Healthy adults taking maximum doses of Tylenol for two weeks had abnormal liver test results in a small study, raising concerns that the popular painkiller might lead to liver damage even at recommended amounts. Read Full Article.
Senator Rick Santorum Introduces National Hepatitis B Act in U.S. Senate
June 30– U.S. Senator Rick Santorum (R-PA) introduced the National Hepatitis B Act (Senate Bill, S.3558) that calls for a comprehensive program in support of hepatitis B. U.S. Senator Diane Feinstein (D-CA) is cosponsor of the bill.
Read Full Article
First Online Television Network for Hepatitis B at www.HepB.tv
June 30 - HepB.tv offers original and syndicated video and audio programming to educate and motivate people to seek testing, vaccination and treatment.
HBV Treatment: Highlights from Digestive Disease Week 2006
June 30– Review of treatment options for chronic hepatitis B and a library of slides and posters from Digestive Disease Week 2006 (DDW).
Read Full Article
What You Should Know About Complementary and Alternative Medicine (CAM)
June 18 - The National Center for Complementary and Alternative Medicine at the NIH has developed a tip sheet for people who are considering using CAM. Read Full Article.
Stem-Cell Research Might Help Repair Damaged Livers
June 18 - If the experimental stem-cell work continues successfully, the technique could one day repair livers badly damaged by drug overdoses, hepatitis and alcoholism. Read Full Article.
Merck Creates New Adult Patient Assistance Program for Vaccines
June 15– Merck & Co has created a new patient assistance program to provide free vaccines, which includes their hepatitis B vaccine, to adults who are uninsured or unable to afford vaccines. Read Full Story.
Coffee Consumption May Protect Liver from Alcohol
June 13 - Coffee may help protect the livers of heavy alcohol drinkers. One to three cups of coffee a day was associated with a 40% decrease in the risk of alcoholic cirrhosis versus drinking less than one cup. Read Full Article.
Cost Effectiveness of Hepatitis B Treatment with Antiviral Agents
June 10 - A study presented at Digestive Disease Week 2006 conference showed that treatment with entecavir is cost-effective compared with either lamivudine or adefovir. Read Full Article.
Treatment of Chronic Hepatitis B: Highlights from EASL Meeting
June 7 - Dr. Emmet Keeffe reviews current and future antiviral therapeutic options. Read Full Article.
Hepatitis B Vaccination Coverage Among Adults -- United States, 2004
June 7– Strategies to vaccinate adults at high risk are critical to eliminating HBV in the U.S., according to recent MMWR Report of the Centers for Disease Control and Prevention. Read Full Article.
Callisto Drug Atiprimod Shows Promise in Advanced Liver Cancer in Phase I Trials
June 6– Three of four advanced cancer patients had measurable tumor regressions and loss of many of the debilitating symptoms of secondary liver cancer with Atiprimod. Read Full Article.
Huge Numbers of Hepatitis B and C Cases in Ireland
June 2 - A huge increase in reported cases of hepatitis B in Ireland over the past decade is due to better screening programmes. Read Full Article.
Fatigue A Lasting Problem After Liver Transplantation
June 2 - A new study found that fatigue (physical vs. mental and reduced activity vs. reduced motivation) after liver transplantation is a major problem that does not tend to improve with time. Read Full Article.
Summer Push for Hep Vaccinations
May 31 - After a successful pilot program in Chicago last summer, the innovative Hep Team is expanding to three major cities this summer to raise awareness among gay and bisexual men that hepatitis A and B are vaccine-preventable. Read Full Story.
Congressional Briefing on Hepatitis B Raises Awareness
May 31– Leaders from the NIH, CDC, and the Hepatitis B Foundation spoke about the urgent need for screening and early detection of hepatitis B at a congressional briefing held on May 11 for key policy makers. Read Full Article.
Hepatitis B Therapy Highlights -- Digestive Disease Week 2006
May 23 - This report addresses key issues of the most clinically relevant treatment options for HBV presented at DDW 2006, as placed within a broader context. Read Full Article.
Asian Immigrants at High Risk for HBV Infection and More
May 23 - CDC reports on the prevalence of chronic HBV among Asian immigrants, indicating the need for improved patient education and screening programs. Read Full Article.
Factors in Quality of Life for Chronic Liver Patients
May 23 - New study shows that health-related quality of life in chronic liver patients is clearly determined by disease severity, joint pain, depression, decreased appetite and fatigue. Read Full Article.
Hepatitis Patients at Risk for Accidental Acetaminophen Toxicity
May 22 - A number of over-the-counter and prescription drugs contain acetaminophen, which may put acute hepatitis patients at risk of acetaminophen toxicity at lower doses than previously recognized. Read Full Article.
Hepatitis Risk for East Asians in New York
May 11 - One in seven East Asian immigrants in New York City carries the hepatitis B virus, a new study has found. Read Full Article.
NVHR To Present Strategic Plan to Congress on May 10, 2006
The National Viral Hepatitis Roundtable (NVHR) will formally present its new plan Eliminate Viral Hepatitis to Congress on Wednesday May 10 on the steps of the U.S. Capitol. Read Full Article.
Congressional Briefing on Hepatitis B Scheduled May 11, 2006
A congressional briefing on hepatitis B will be held on May 11, 2006 in Washington, DC, for leaders from the NIH, CDC and Hepatitis B Foundation to highlight this disease among key policy makers. This is a follow-up to the Briefing held last summer. Read Full Article.
HBV Treatment Updates from EASL Meeting 2006
May 1 - HIV and Hepatitis has posted previews of selected studies from Annual Meeting of the European Association for the Study of the Liver (EASL) held April 26-30 in Vienna, Austria. Read Full Article.
FDA Grants Orphan Drug Designation to Nexavar for the Treatment of Hepatocellular Carcinoma
April 26 - The U.S. Orphan Drugs Act encourages the development of drugs for the diagnosis, prevention, or treatment of a medical condition that affects less than 200,000 Americans. Hepatocellular cancer, or liver cancer, is a highly fatal disease. Read Full Article.
NVHR Strategic Plan to Eliminate Viral Hepatitis Now Released!
April 19 - The first-ever national hepatitis plan has just been released by the National Viral Hepatitis Roundtable. It calls for all Americans to work together to bring an end to the needless suffering caused by viral hepatitis in the United States. Click here to read the full “Eliminating Hepatitis: A Call to Action”.
Online Cancer Resource Helps Asian Americans
April 13 - Asian Americans can now access online cancer information written in a variety of languages via a Web site funded by the National Cancer Institute and launched by the American Cancer Society and the Asian American Network for Cancer Awareness, Research and Training. Read Full Article.
Liver Biopsy Not Foolproof
April 12 - Liver biopsy is considered a gold standard for staging chronic liver disease, but sometimes it’s fool's gold, according to data reported at the American College of Physicians meeting. Read Full Story.
Experts at NIH Meeting Agree Key Issue in Hepatitis B Treatment is to Avoid Drug Resistance
April 10 - The National Institutes of Health (NIH) convened a national meeting to address current controversies in the management and treatment of hepatitis B and to make recommendations on directions for future research. Although there was vigorous debate on every issue, the experts all agreed that resistance to the currently approved drugs is a key concern in the treatment of hepatitis B. Read Full Article.
“The Vaccinators” Hit London Bars to Promote Hepatitis Vaccination
April 7 - Arriving in a “superhero” bus, men dressed as “The Vaccinators” launched a vaccine campaign to stamp out hepatitis A and B in the gay community. Read Full Article.
Oklahoma State House Panel Passes Tattoo Regulation Measure
April 5 - Oklahoma legislators are responding to an increase in hepatitis cases blamed on unsanitary tattooing practices, with an HBV outbreak in 2004 linked to home tattooing. Read Full Article.
Monotherapy vs. Combination Therapy for the Treatment of Chronic HBV?
April 4 - The issue of monotherapy vs. combination therapy for chronic HBV was a topic for debate at the 2006 Shanghai-Hong Kong International Liver Congress held in China. Read Full Article.
Pros and Cons of Serologic Clearance of HBsAg as a Treatment Endpoint for Chronic HBV Infection
April 4 – Whether serologic clearance of HBsAg is the best treatment endpoint for patients with chronic HBV infection was discussed at the 2006 Shanghai-Hong Kong International Liver Congress. Read Full Article.
Characteristics of Drug Resistant HBV in Co-infected HIV/HBV Individuals on Extended Lamivudine Therapy.
April 4 – The issue of greater immunocompromise and drug resistance among HIV co-infected patients makes the timing and selection of HBV therapy critical in this population. Read Full Article.
Telbivudine Provides Greater Response than Lamivudine in Chinese Patients with Chronic HBV
March 27 - New clinical data demonstrates telbivudine provides both superior antiviral and clinical efficacy in Chinese patients after one year of use when compared with lamivudine. Read Full Article.
American Academy of Pediatrics Endorses CDC's HBV Recommendations for Infants, Children, and Adolescents
March 27 - CDC recommends ALL newborns receive the first dose of HBV vaccine before leaving the hospital, and ALL children and teens up to 19 years of age be vaccinated. Read Full Article.
Phase 2 HBV Data Show Strong Efficacy for Pradefovir Mesylate
March 19 – Pradefovir, using Metabasis’ pro-drug technology to achieve higher concentrations of adefovir in the liver, shows significant viral load reduction. Read Full Article.
Man Claims He Got Hepatitis Through Illegally Harvested Tissue
March 23 - A Nebraska man claims he contracted hepatitis B and C through a tissue transplant that was illegally harvested in a massive scam of stolen body parts. Read Full Article.
Impact of HBV on Liver Transplantation in the U.S.
March 20 – HBV is generally considered to be a minor health issue by many gastroenterologists; however, with growing immigration from overseas, it may eventually have a big impact on liver transplants. Read Full Article.
Menatetrenone Improves Hepatocellular Carcinoma Outcome
March 16 – Results of a pilot study suggest menatetrenone for hepatocellular carcinoma (primary liver cancer) reduces recurrences and improves survival. Read Full Article.
HBV DNA Levels Early Predictor of Nonresponse with Interferon alpha
March 17 – HBV DNA testing at baseline and 12 weeks has high predictive value for identifying patients who will not reach sustained response with IFN therapy. Read Full Article.
Phase 2 HBV Data Show Strong Efficacy for Pradefovir Mesylate
March 19 – Pradefovir, using Metabasis’ pro-drug technology to achieve higher concentrations of adefovir in the liver, shows significant viral load reduction. Read Full Article.
Transient Elastography Detects Cirrhosis in Chronic Liver Disease
March 9 - FibroScan, a noninvasive technique that measures liver fibrosis, accurately detects cirrhosis in patients with chronic liver disease. Read Full Article.
Diabetes Associated with an Increased Risk for Hepatocellular Carcinoma (HCC)
March 8 – A significant association between HCC and diabetes, independent of alcohol use or viral hepatitis, was found in a review of 10 studies. Read Full Article.
Baraclude Trumps Epivir as HBV Therapy
March 8 - Two international studies showed that Baraclude (entecavir) appears to be superior to Epivir-HBV (lamivudine) at reducing viral loads in patients with HBV. Read Full Article.
The Extrahepatic Consequences of Cirrhosis
March 3 - Cirrhosis can result in serious damage to the liver, as well as other vital organs. Read Full Article.
Ask the Experts about Hepatitis B
March 3 – What is your diagnosis of a 32 year old patient with HBeAg-negative/HBeAb-positive, normal ALT, and high viral DNA? Read Dr. Paul Martin’s Answer.
HBV Infection Predicts Clearance of HCV in Hemophiliacs
Feb 28 - Consistent with what has been seen in other patient groups, chronic HBV infection was associated with a nine-fold increased chance of HCV clearance in hemophiliac patients. Read Full Article.
Gilead Sciences Launches STOP Hep B Campaign
Feb. 28 – Community partnerships and interactive online education provide opportunities for patients and caregivers to “stop hepatitis B” together. Read Full Article.
UK Issues HBV Treatment Guidance
Feb. 21 - The U.K. National Institute for Health and Clinical Excellence recommends the use of two new drugs for treating hepatitis B. Read Full Article.
New Compound May Protect Against Liver Cancer
Feb. 15 - National Cancer Institute researchers found a new compound that protects against the development of liver cancer in lab animals. Read Full Article.
ANA380 Shows Robust HBV Viral Reduction
Feb. 14 - Anadys announced that ANA380 in phase II trials showed significant viral load reduction in patients with lamivudine-resistant HBV. Read Full Article.
AIDS Overtakes HBV in China
Feb. 13 - The Chinese government said that AIDS surpassed hepatitis B as the country's third-deadliest infectious disease in 2005. Read Full Article.
HBV Genotype Linked to Liver Damage in HIV Co-Infections
Jan. 31 - A study found that the degree of liver damage in HIV/HBV co-infected patients is affected by HBV genotype. Read Full Article.
National Hepatitis B Act Reaches Congress!
The first-ever hepatitis B legislation H.R. 4550, the "National Hepatitis B Act" was introduced by U.S. Representatives Mike Honda (D-CA) and Charles Dent (R-PA) to Congress on December 15 in an historic bi-partisan effort. Read Full Article.
Overall Cancer Deaths Still Dropping, But Liver Cancer is Increasing
Oct. 5, 2005- Liver cancer seems to be on the rise researchers reported in the Journal of the National Cancer Institute, a blip of bad news in the nation's otherwise optimistic annual report on cancer that shows survival continuing to improve. One factor may be hepatitis infections. Read Full Article.
Stalking a Cancer That's Silent and Deadly
Oct. 11, 2005- The New York Times reports that although you don't hear much about liver cancer, its incidence is increasing faster than any other cancer in the United States – an increase that is expected to continue for two more decades. The striking increase in liver cancers here and in other developed countries is a result of chronic and usually silent infections by the hepatitis B and C viruses. Read Full Article in the New York Times.
Hepatitis B Vaccine Considered For All Adults
Sept. 26, 2005- Many in the health community believe the time is right to broaden the assault against hepatitis B, and they hope to persuade the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices to recommend its vaccine for all adults. The committee is scheduled to discuss the vaccine during its Oct. 26-27 meeting. Read Full Article.
New Web Site to Track Clinical Drug Trials
Sept. 22, 2005- The International Federation of Pharmaceutical Manufacturers and Associates, a trade group for the global drug industry, has launched a new website at www.ifpma.org/clinicaltrials. It is designed to help users navigate 250,000 links to find clinical trials information and results on other sites run by federation members and government and nonprofit groups. Read Full Article.
Europe Suspends Sales of Pediatric Vaccine
Sept. 20, 2005 - The European Medicines Agency has suspended sales of Sanofi Pasteur Merk's childhood vaccine Hexavac because of concerns about the long-term protection against hepatitis B. Experts at the London-based agency have identified a problem with the hepatitis B element of the shot, resulting in decreased ability of the vaccine to stimulate an immune response. Hexavac is a vaccine for infants and children against diphtheria, tetanus, whooping cough (pertussis), hepatitis B virus, polio virus and Haemophilus influenzae type b.
Thinking Outside the Black Box: Toward Optimal Treatment of Chronic Hepatitis B in HIV Patient
Sept. 14, 2005 – Treatment and management of HIV-HBV coinfection represents a growing concern both in the US and worldwide, where health authorities estimate more than 300 million persons are living with chronic hepatitis B, 40 million with HIV-1 infection, and an unknown number living with both these viral infections. HIV contributes to HBV disease progression and HBV hastens progression of HIV disease. Read Full Article.
Relationship of Genotypes of HBV to Mutations, Disease Progression and Antiviral Therapy
Sept. 13, 2005 –Genotypes may account not only for differences in the prevalence of HBV mutants in various geographic regions, but also for differences in clinical outcome and response to therapy, according to a report in the J. of Viral Hepatology 12(5) 2005. Read Full Article.
Why Treat Hepatitis B Now? The Clinical View
Sept, 12, 2005 – This Treatment Update, by Dr. Emmet Keeffe at Stanford U. School of Medicine, includes CME-certified Educational Modules as well as Interactive Case Challenges and is now available to you on the Clinical Care Options Web site. Read Full Article.
HBF and IHVR Scientists Report On GP73, a Resident Golgi Glycoprotein, is a Novel Serum Marker for Hepatocellular Carcinoma
Sept. 6, 2005 - HBF and IHVR scientists reported in the J. of Hepatology (Aug. 30, 2005) that GP73 was better than AFP for the diagnosis of early HCC. Further validation studies are needed to confirm the role of GP73 in the early detection of HCC. Read Full Article.
Impact of Chronic Viral Hepatitis on Health-Related Quality of Life in HIV
Sept. 6, 2005 - Little is known about the health burden of chronic viral hepatitis in HIV-infected patients. A study compared health-related quality of life of patients with HIV and hepatitis C virus (HCV) or HIV and hepatitis B virus (HBV) coinfection to those with HIV monoinfection. Findings were reported in Am J Gastroenterology (Sept. 2005). Read Full Article.
Thalassemic Children at Higher Risk of Acquiring Hepatitis
Sept. 4, 2005 - In India, every year about 10,000 children are born with thalassemia, which represents 10% of the total number of thalassemic children born worldwide. Since thalassemic patients have to undergo blood transfusion regularly, they are at a higher risk of acquiring hepatitis B and C. Read Full Article.
24 HBV Therapies and Vaccines are FDA-approved or In Development
Aug. 29, 2005 - With FDA approval in 2005 of peginterferon alfa-2a (Pegasys) and Entecavir (Baraclude), there is now an impressive 40% percent increase in the number of approved drug treatment options for HBV infection. Read Full Article.
HIV and Hepatitis B Virus Coinfection: Question and Answers
Aug. 25, 2005 - Learn about the current treatment of hepatitis B in the setting of HIV infection, emerging therapeutic strategies, and therapeutic guidelines. Read Full Article.
Eating Soy May Ease Liver Cancer Risk, Claim Scientists
Aug. 25, 2005 - Adding soy to your diet may be the key to keeping liver cancer at bay, says an international team of scientists who studied the effect of this soybean-derived substance in a group of Japanese people at risk for the disease. Read Full Article.
Research Proves Black Tea as Powerful as Green, Yet Consumers Don't Recognize Health Benefits
Aug. 23, 2005 - A recent survey reveals that Americans overwhelmingly associate health benefits with green tea and overlook the health benefits of regular, black tea. Seventy-one percent identify hot green tea as a good source of antioxidants, while only 34 percent of respondents view regular hot tea as a good source of antioxidants. In fact, regular (black) and green tea have virtually the same amount of antioxidants. Read Full Article.
Online Registration Now Available for HepDART 2005 Conference
Aug. 18, 2005 – The bi-annualHepDART conference will be held in Hawaii Dec 11-15, 2005. The goal is to bring clinicians, researchers, and basic scientists together to advance the knowledge of drug development in the treatment of hepatitis B and C. Visit www.informedhorizons.com/hepdart2005/
A One Year Trial of Telbivudine, Lamivudine, and the Combination in Patients With Hepatitis B e Antigen-Positive Chronic Hepatitis B
Aug. 18, 2005 - The results of a study comparing telbivudine, telbivudine and lamivudine vs. lamivudine alone in the treatment of hepatitis B e-antigen positive adults with compensated chronic hepatitis B was reported in Gastroenterology 2005 (Aug;129). Read Full Article .
Viral Link to Liver Cancer Found
Aug. 17, 2005 - Doctors at the MD Anderson Cancer Center in Texas report that they've found how HBV can help mediate the development of liver cancer in people with the viral infection. This finding paves the way for a possible treatment, either to prevent liver cancer or for people who already have the disease, the researchers point out. Read Full Article.
Open Wide: Dental Health and Viral Hepatitis May Be More Important Than You Think
Hepatitis Magazine (July-Sept 2005) - There are three important issues for patients to consider – the special dental concerns of hepatitis patients, the risk of transmission to the dentist (which is greatly decreased due to a safe vaccine), and the strict dental requirements for the patient who needs a transplant. In many instances, poor dental health can result in a patient being rejected for transplant. Read Full Article.
HIV/Hepatitis Coinfections: Special Treatment Issues in Patients With Liver Disease
Aug. 9, 2005 - Diseases such as end-stage liver disease are replacing opportunistic infections as leading causes of mortality in patients with HIV disease. In some patient populations, almost all individuals will carry both HIV and hepatitis C virus (HCV), many will have hepatitis B virus (HBV) coinfection, and some will be infected with all 3 viruses. An expert interview with Paula Greiger, MD, discusses the additional challenges posed by these hepatitis coinfections. Read Full Article.
Telbivudine Achieves Primary Endpoint in Phase III
GLOBE Trial, Largest Ever Registration Trial in Hepatitis
July 28, 2005 -The largest hepatitis B registration trial to date, GLOBE trials, sponsored by Idenix and Novartis, enrolled more than 1,350 patients in over 130 medical centers worldwide. The ongoing trial is evaluating the safety and efficacy of telbivudine compared to lamivudine in patients with HBeAg-positive and HBeAg-negative compensated chronic hepatitis B for two years of treatment. Read Full Article.
Lamivudine Prophylaxis in HBV Carriers Receiving Chemotherapy
July 25, 2005 - Reactivation of hepatitis B virus (HBV) is a well-recognized complication of chemo/immunosuppressive therapy in individuals who are HBV surface antigen-positive inactive carriers and in individuals with chronic HBV infection. Read Full Article.
Gilead Initiates Phase III Clinical Trials for Tenofovir for
Chronic Hepatitis B
July 19, 2005 - Gilead Sciences has begun enrolling patients in its Phase III clinical program evaluating the oral antiviral drug tenofovir disoproxil fumarate (tenofovir DF) for the treatment of chronic hepatitis B. Two Phase III clinical trials (Studies 102 and 103) will evaluate tenofovir DF among patients with either hepatitis B "e" antigen (HBeAg)-positive chronic hepatitis B or HBeAg-negative/anti-hepatitis B "e" positive (anti-HBe positive) chronic hepatitis B. Read Full Article.
Experimental HBV Drug Pradefovir Shows Promising Phase 2 Results
July 19, 2005 - Valeant Pharmaceuticals reports promising 24-week interim data from a Phase 2 study of its oral antiviral compound pradefovir. The company is evaluating the safety and efficacy of pradefovir for the treatment of compensated chronic hepatitis B. Read Full Article.
Is Routine Screening for HCC Recommended for the Hepatitis
B Patient in the Inactive Carrier State?
July 19, 2005 - Dr. Emmet Keeffe, Professor of Medicine, Chief of Hepatology, Medical Director, Liver Transplant Program, Stanford University Medical Center, Stanford, California, responds to this question in a comprehensive manner. Read Full Article.
CDC Releases Guidelines for Improving HBV Vaccination Rates
Among High-Risk Adults
July 15, 2005 – The Centers for Disease Control and Prevention (CDC) has issued guidelines to improve influenza, pneumococcal polysaccharide, and hepatitis B vaccination coverage among high-risk adults younger than 65 years. Although vaccines are effective and widely available, vaccination rates remain low. Read Full Report.
New England Journal of Medicine Article Supports PEGASYS as
a First-Line Therapy in Chronic Hepatitis B
June 29, 2005 - According to a major study published in the June 30 edition of the New England Journal of Medicine, patients with the most common form of hepatitis B in the United States who are treated with PEGASYS(R) (peginterferon alfa-2a) are more likely to achieve a sustained response than those treated with lamivudine, the current standard of care. "Good therapeutic options are what people affected by hepatitis B need. This appears to be another important step forward," said Timothy M. Block, Ph.D., president of the Hepatitis B Foundation. Read Full Article.
Panel Backs Tougher Hepatitis B Guidelines
June 29, 2005 - Vaccine experts voted Wednesday to strengthen a national recommendation that all healthy newborn babies get a hepatitis B shot before leaving the hospital, saying "exceptions should be rare" and should require documentation and follow-up. Read Full Article.
Science Making Headway Against Hepatitis B
June 29, 2005 - Two new studies suggest researchers are moving closer to finding the best treatments for chronic hepatitis B for specific patients. Dr. Anna S.F. Lok, a renowned hepatologist, wrote an editorial that accompanies the studies in the June 30 issue of the New England Journal of Medicine. Read Full Article.
NIH Requests Applications for Clinical Studies of Milk Thistle
in Chronic Liver Disease
June 29, 2005 - The National Institutes of Health have a keen interest in studying the potential benefits of silymarin (milk thistle) on the liver. Dr. Jay Hoofnagle, of the Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), writes about the NIH-initiated effort to conduct the first scientifically rigorous study of silymarin in Hepatology July 2005. Milk thistle has been used for centuries to treat acute and chronic liver diseases. A letter of intent is requested by August 15, 2005 and final applications by September 12, 2005. Applicants are limited to the United States. For details, visit the NIH grant page. Read Full Article.
Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical
Learn more about milk thistle from the Agency for Healthcare Research and Quality, Rockville, MD. Read Full Article.
Dynavax Starting Phase III Trial of Vaccine for Hepatitis B
June 24, 2005 - Aiming to file a biologics license application in 2007, Dynavax Technologies began a pivotal Phase III trial to test its HBV vaccine against Engerix-B (GlaxoSmithKline, or GSK), in older adults. Dynavax reported positive data from a Phase II/III trial with the vaccine, which showed statistically significant superiority in protective antibody response and robustness of protective effect after three vaccinations vs. GSK's product in older adults. Read Full Article.
Soy Intake Linked With Reduced Hepatocellular Carcinoma Risk
June 21, 2005 - Consuming miso soup and other soy foods may reduce the risk of hepatocellular carcinoma (HCC), according to the results of a study published in the June 10th issue of the International Journal of Cancer. The team adjusted for hepatitis B and C viral infection, which are major HCC risk factors in this population. Read Full Article.
Pharmasset to Develop Clevudine for the Treatment of Chronic
June 27, 2005- Pharmasset and Bukwang Pharm. Co. announced that they have entered into an exclusive license agreement under which Pharmasset will develop and commercialize Clevudine, also known as L-FMAU, for the treatment of chronic hepatitis B virus (HBV) infections in the Americas, Europe, and other select territories. Clevudine is a potent oral, once-daily HBV antiviral drug currently in Phase 3 clinical trials in Korea and has been the subject of earlier stage clinical trials under an Investigational New Drug application filed with the US FDA. Read Full Article.
Double Dose of Hepatitis B Vaccine More Effective for HIV Patients
June 21, 2005- A study reported in Vaccine shows that a double dose of a commonly used hepatitis B vaccine is [more] effective in preventing the disease in HIV-positive adults. Read Full Article.
Combination of Nucleoside Analogues in the Treatment of Chronic
June 16, 2005- Owing to the persistence of hepatitis B virus and the selection of drug-resistant mutants, antiviral therapy for chronic hepatitis B relies on the combination of nucleoside analogues. Read Full Article.
NIH Grant for Stem Cell Research for Hepatitis and Cirrhosis
June 14, 2005- Vesta Therapeutics will research use of adult stem cells as a possible treatment for liver disease with funding from the National Institutes of Health. Read Full Article. Read Rudy's Story with Stem Cell Transplant for HBV.
Fibromyalgia Frequency in Hepatitis B Carriers
June 8, 2005- Fibromyalgia (FM) is characterized by diffuse musculoskeletal pain, fatigue, morning stiffness, and sleep disturbance. A study reported in the Journal of Clinical Rheumatology (June 2005) study suggests that chronic hepatitis B appears to increase the risk of FM and many of the typically associated symptoms…physicians should be aware of this apparent association. Read Full Article.
New Antiviral Therapies for Hepatitis B
June 6, 2005- Dr. Anna Lok provides an excellent overview of current antiviral therapies for chronic hepatitis B. After a brief discussion of treatment goals and the efficacy of currently
approved medications, new therapeutic agents and combination therapies that are now in clinical trials are reviewed. Read Full Article.
Bayer Receives FDA Approval for Hepatitis B Tests
June 6, 2005 - Bayer HealthCare received approval from the U.S. Food and Drug Administration (FDA) for its automated HBsAg (hepatitis B surface antigen) Diagnostics and HBsAg Confirmatory assays. The fully automated tests, which are used to aid in the diagnosis and confirmation of acute or chronic hepatitis B infections, brings to eight the total number of hepatitis assays available – the most comprehensive, automated hepatitis (A, B and C) testing portfolio available in the U.S. Read Full Article .
Hepatitis B Virus May Be a Risk Factor for Other Cancers Besides
June 1, 2005 - It is well known that chronic infection with the hepatitis B virus (HBV) is a major risk factor for hepatocellular carcinoma. However, HBV might also favor the development of other types of cancer, according to data presented at the DDW 2005 conference in Chicago (May 14-18, 2005). Read Full Article
Doctors Fight Liver Disease With Body's Own Stem Cells
May 28, 2005 - British doctors have made a "significant" breakthrough using patients' own stem cells to regrow their livers, raising the possibility of it replacing organ transplants in future. Read Full Article
Adefovir Dipivoxil Demonstrates Sustained Efficacy in HBeAg-negative
Chronic Hepatitis B Patients
May 23, 2005 - Adefovir Dipivoxil (Hepsera) demonstrated efficacy and safety in 184 HBeAg-negative chronic hepatitis B (CHB) patients enrolled in a 96-week randomized, placebo -controlled trial. Patients on Adefovir in the second 48 weeks were offered up to 3 additional years of the drug. Read Full Article
Treatment With Adefovir Results in Sustained Reductions of
HBV DNA Levels
May 20, 2005 - Treatment with 10 mg of adefovir dipivoxil for 192 weeks resulted in significant and sustained reductions in hepatitis B virus (HBV) DNA virus levels, with the majority of patients achieving prolonged HBV DNA suppression and sustained ALT normalization, according to findings presented at Digestive Disease Week 2005.The study indicates that adefovir dipivoxil provides durable HBV DNA suppression and a low incidence of resistance. Read Full Article
Entecavir Could Dominate First-Line Hepatitis-B Monotherapy
May 19, 2005 - Bristol-Myers Squibb's recently-launched anti-hepatitis B (HBV) drug, entecavir (Baraclude), could dominate the hepatitis-B therapeutic market, according to information reported in Pharmaprojects, the leading pharmaceutical pipeline-tracking database. Results presented at the recent 18th International Conference on Antiviral Research held in Barcelona, Spain, last month appeared to support entecavir's superiority over the widely-used anti-hepatitis-B drug, lamivudine (Epivir). Read Full Article
Advances in the Management of Hepatitis B
May 18, 2005 - The current treatment guidelines for HBV infection, which were revised in 2004, are already outdated. The field is evolving at a rapid pace, and what is accepted as the current standard of therapy will likely change in the next year. This report focuses on current therapies as well as new concepts that are evolving in the management of hepatitis B, as based on key data presented during this year's meeting of the European Association for the Study of the Liver (EASL). Read Full Article
Positive Two-Year Data for Telbivudine for the Treatment of
Chronic Hepatitis B
May 16, 2005 - According to a presentation given at the 2005 Digestive Disease Week (DDW) meeting, Telbivudine treatment nearly doubles proportion of patients achieving clinical efficacy measures compared to lamivudine. Data analysis indicates rapid and profound viral suppression early in the course of therapy is linked with better clinical outcomes out to two years. Read Full Article
FDA Approves Pegasys for the Treatment of Chronic Hepatitis
13 May 2005 - Roche announced today that the U.S. Food and Drug Administration (FDA) has approved Pegasys(R) (peginterferon alfa-2a), the most prescribed hepatitis C medication in the United States, for the treatment of chronic hepatitis B (CHB). Pegasys is the first and only pegylated interferon approved for the treatment of chronic hepatitis B, including both variations of the virus - HBeAg-positive and HBeAg-negative chronic hepatitis B. Read Full Article.
FDA Approves Baraclude (entecavir) for Chronic Hepatitis B
29 March 2005 - Bristol-Myers Squibb announced that the U.S. Food and Drug Administration (FDA) approved the oral antiviral drug BARACLUDE (entecavir) for the treatment of chronic hepatitis B infection in adults. The drug will be available in the United States as early as April 8, 2005. Read Full Article.
HBV 2005 International Meeting Open for Registration
This year marks the 20th anniversary of the International Meeting on the Molecular Biology of Hepatitis B Viruses, which will be held September 18-21 at the Kirchhoff Institute in Heidelberg, Germany, and organized by Drs. Timothy Block and Stephan Urban. It remains the definitive international meeting that covers all aspects of the biology, virology, immunology and pathogenesis of hepatitis B and hepatitis D, as well as the latest developments in antiviral therapies against these two viruses. Abstract submission deadline is July 18, 2005 and a limited number of travel grants for graduate students and post docs are available. For more information or to register, visit www.hbvmeeting.org.
New Clinical Trial Opens Comparing Entecavir vs. Adefovir
Bristol Myers Squibb is conducting a Phase IIIb comparative study of entecavir vs. adefovir in patients who have chronic hepatitis B. The treatment period is for up to 96 weeks. The study began January 2005 and trial sites are located throughout the US and Canada. Contact: Bristol-Myers Squibb toll-free at 1-866-892-1267 ext. 150.
PKIDS Launches Listservs For Kids With Hepatitis B and C
Jan. 10, 2005- Thanks to PKIDs, children and teens living with hepatitis C or B now have their own Internet listservs, giving them a chance to "talk" with other infected youth from around the United States and the world. The two listservs, one for children ages 8 to 12 and one for teens ages 13 to 19, are designed to allow youth the freedom to speak from their hearts. To help ensure a safe environment, the lists are moderated and there are no identifiers for those posting to the lists.
PKIDs (Parents of Kids with Infectious Diseases) is a national nonprofit organization serving families of children infected with chronic viral hepatitis and HIV/AIDS.
To access the listservs, go to: www.pkids.org/listserv.htm and click on the appropriate link.
NIH Action Plan Charts Future Challenges For Liver Disease
Jan. 3, 2005 - The National Institutes of Health (NIH) released the trans-NIH "Action Plan for Liver Disease Research", a comprehensive plan that addresses the burden of liver diseases in the United States and maps out challenges for future research over the next decade. The Action Plan is available at http://liverplan.niddk.nih.gov.
Standard Tests Miss Most Hepatitis B Infections
Jan. 5, 2005 - Researchers in Canada report that hepatitis B may affect people in the general population at rates higher than previously suspected. In a study with 241 dialysis patients, every person who tested positive on the standard test, four or five more patients were found to be infected when on the more sensitive DNA test. CDC HIV/STD/TB Prevention News Update (1/5/05). Read Full Article.
Clinical Relevance of HBV Genotype in Children and Hepatocellular
Dec. 6, 2004 – The aim of this Taiwanese study was to investigate the influence of HBV genotypes on the clinical outcome of chronic childhood HBV infection and hepatocellular carcinoma (HCC). A total of 460 HBV carrier children were followed-up for 15 years and 26 children with HBV-related HCC were recruited. Gastroenterology, Dec. 2004 (127:6). Read Full Article.
Oral Hepatitis B Vaccine Clears Early Hurdle As Potential New
Dec. 3, 2004 – MicroScience a UK company, has completed a Phase I study of a new therapeutic vaccine for patients with chronic hepatitis B. It is given orally and provides a new approach to clearing the hepatitis B virus. The oral vaccine appears to stimulate the appropriate type of immune response required to promote clearance of the hepatitis B virus in chronic carriers. Read Full Article.
Entecavir Better Than Lamivudine In Chronically Infected Hepatitis
October 31, 2004- According to data to be presented at the 55th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), the Bristol-Myers Squibb Company investigational chronic hepatitis B compound entecavir demonstrated significantly greater improvements in both liver histology and reductions of hepatitis B virus (HBV) DNA levels compared to lamivudine in two studies investigating both nucleoside-naïve, e-antigen-negative (HBeAg-) chronic hepatitis B patients (Study AI463-027) and e-antigen-positive (HBeAg+) chronic hepatitis B patients who had developed resistance to lamivudine (Study AI463-026) -- both multinational, double-blind, Phase III clinical trials. Read Full Article.
GlaxoSmithKline vaccine, Fendrix®, to prevent infection
from hepatitis B for specific high-risk patients to be approved soon
October 27, 2004 - GlaxoSmithKline has received a positive opinion from the Committee for Medical Products for Human Use (CHMP) of Europe dated Oct. 215, 2004, for its new adjuvanted hepatitis B vaccine Fendrix® for high-risk patients. Official approval is anticipated in three 3 months. Read Full Article.
Widespread Dissemination of Single HBV Variant in England
Oct 14, 2004 - Over a 10-year period in England, an "unexpectedly high proportion" of cases of acute hepatitis B infections were caused by a single variant, UK epidemiologists have discovered.
Reuters Health Information 2004. Read Full Article.
Rituxan May Be Associated With HBV Reactivation and Fulminant
Oct. 9, 2004 - The FDA has received reports of fulminant hepatitis, hepatic failure, and death among some patients with hematologic malignancies, such as non-Hodgkin's lymphoma, taking rituximab (Rituxan) therapy. The FDA recommends that patients at high risk of HBV infection be screened before initiation of rituximab therapy. Hepatitis B carriers should be closely monitored during therapy. Medscape 2004. Read Full Article.
Caffeine Breath Test Measures Liver Function
Oct. 11, 2004 (Reuter) - Forget the liver biopsy. Now it's possible to detect advanced fibrosis -- a complication of many liver diseases including hepatitis B, hepatitis C, fatty liver disease and hemochromatosis -- by means of a simple breath test. Read Full Article.
Bristol-Myers Squibb Submits Applications In U.S. And Europe
To Market Entecavir
October 4, 2004- Bristol-Myers Squibb Company (NYSE: BMY) today announced the submission of a New Drug Application to the U.S. Food and Drug Administration for entecavir, an investigational antiviral agent under development for the treatment of chronic Hepatitis B. Read Full Article.
Sustained Response After a 2-Year Course of Lamivudine Treatment
of Hepatitis B e Antigen-Negative Chronic Hepatitis B
September 24, 2004- Hepatitis B e antigen-negative chronic hepatitis B is characterized by the absence of hepatitis B e antigen, detectable serum hepatitis B virus DNA by non-PCR-based assays, and liver necroinflammation. J Viral Hepat 11(5) 2004. Read Full Article.
Hepatitis B Virus Genotype C Linked to Increased Hepatocellular Carcinoma RiskSeptember 23, 2004- Patients infected with hepatitis B virus (HBV) genotype C, face an increased risk of hepatocellular carcinoma compared with patients infected with HBV genotype B, according to a report in the October issue of Gut. Read Full Article.
Tenofovir and Lamivudine Combination Therapy for 96-weeks in
HIV and HBV Co-infected Patients Effective
September 22, 2004- Researchers in France describe results of a pilot study of 6 individuals coinfected with HIV and HBV, in whom complete and sustained suppression of HBV was attained during 96 weeks of combination therapy with lamivudine (Epivir-HBV) and tenofovir (Viread). Read Full Article.
Ask the Experts- Chronic Hepatitis B- Role of Liver Biopsy
September 20, 2004- Is a liver biopsy necessary in a patient who is HBsAg-positive, HBeAg-negative, has normal liver enzymes, and has detectable HBV DNA on PCR? Emmet B. Keeffe, MD, explores the issues. Medscape Gastroenterology 6(2)2004. Read Full Article.
Pegasys Study Published in New England Journal of Medicine
This study compares Pegasys, (peginterferon alpha-2a), to lamivudine in
patients with hepatitis B antigen (HBeAg) negative chronic hepatitis B and
finds it is more effective. Read Full Article.
NIH Proposes Free Access for Public to Research Data
September 8, 2004- The National Institutes of Health (NIH) has proposed a major policy change that would require all scientists who receive funding from the agency to make the results of their research available to the public for free. The proposal, posted on the agency's Web site late Friday and subject to a 60-day public comment period, would mark a significant departure from current practice, in which the scientific journals that publish those results retain control over that information. Read Full Article.
Four Years of Treatment With Lamivudine: Clinical and Virological
Evaluations in HBe Antigen-Negative Chronic Hepatitis B
August 16, 2004- Most information on the efficacy of lamivudine (Lam) in the treatment of chronic hepatitis B (CHB) has been derived from studies on patients with disease sustained by wild-type hepatitis B virus (HBV).[1,2] In this setting therapeutic remissions are marked by durable seroconversion from HBe antigen (HBeAg) to antibodies to HBeAg (anti-HBe) and by the normalization of liver enzymes and clearance of serum HBV DNA. Read Full Article.
Preventing Vertical Transmission of Hepatitis B
Approximately 350 million people worldwide are chronically infected with hepatitis B virus (HBV), and over 1 million die each year. Given the worldwide importance of chronic HBV, it is imperative that vertical transmission, a major route of infection, be halted. Perinatal transmission of HBV results from exposure of fetal mucous membranes to infectious maternal blood or serum-derived body fluids. Read Full Article.
Current Issues in Hepatitis B
Hepatitis B virus (HBV) infection remains a global health concern. It is estimated that 2 billion individuals worldwide have been infected with this virus; 350 million are chronically infected, and 50 million new cases are diagnosed annually. Implementation of HBV vaccination programs has led to significant reductions in the HBV infection rate among children and healthcare workers. Read Full Article.
CDC Reports on Transmission of Hepatitis B Virus in Georgia
August 13, 2004- Incarcerated persons have a disproportionate burden of infectious diseases, including hepatitis B virus (HBV) infection. Among U.S. adult prison inmates, the overall prevalence of current or previous HBV infection ranges from 13% to 47%. The prevalence of chronic HBV infection among inmates is approximately 1.0%-3.7%, two to six times the prevalence among adults in the general U.S. population. Read Full Article.
CDC's Division of Viral Hepatitis Redesigns MSM Web Section
August 13, 2004- CDC's Division of Viral Hepatitis recently launched a web section that provides information about preventing hepatitis A and hepatitis B among men who have sex with men (MSM). Even more recently, the page was redesigned to better meet the needs of gay and bisexual men themselves, rather than just health care professionals. Click here to access fact sheets, articles, recommendations, and other specialized publications such as the National Minority AIDS Council's full-color booklet "Protect Yourself from Hepatitis." Health care providers can also use the site to download posters and brochures for their MSM clients.
Adefovir Dipivoxil and Tenofovir Are Highly Efficacious Therapies
in HBV Patients with Lamivudine Resistance
August 13, 2004- Emergence of lamivudine (Epivir-HBV)-resistant hepatitis B virus (HBV) is a major concern in HIV and HBV coinfected patients. Treatment of patients with new nucleotide analogues such as adefovir dipivoxil/ ADV (Hepsera) or tenofovir disoproxil fumarate/ TDF (Viread) has shown good efficacy in controlling wild-type or lamivudine-resistant HBV replication. Read Full Article.
High HBV Transmission Rates in Prisons Are Preventable
August 5, 2004- Rates of hepatitis B virus (HBV) transmission are high in state correctional facilities. However, most inmates appear to be willing to undergo vaccination, which would prevent HBV transmission during incarceration and reduce transmission in the community after their release. Reuters Health Information, 2004. Read Full Article.
In Dose Escalation Study, Clevudine Shows Potent Anti-HBV Effects
24 Weeks After Cessation of Once Daily Dosing
August 2, 2004- Current approved therapies for the treatment of chronic hepatitis B virus (HBV) infection are limited in their ability to produce a cure or to durably suppress the virus. Several promising new anti-HBV drug candidates are now in Phase II or Phase III clinical trial, including entecavir (Phase III), emtricitabine (Phase III; NDA filed), peginterferon alfa-2a (Pegasys) (Phase III), telbivudine (Phase III), valtorcitabine (Phase II), amdoxovir (Phase II), and clevudine (Phase II in US; Phase III in South Korea). Clevudine is a pyrimidine analog that has demonstrated potent anti-HBV activity in vitro and in animal models. Read Full Article.
Management of the Coinfected Patient: HIV/Hepatitis B and HIV/Hepatitis
July 27, 2004- Deaths from liver disease have increased in persons infected with human immunodeficiency virus (HIV) because of coinfection with chronic hepatitis B and C; consequently, all HIV-infected patients should be screened for hepatitis B and C, and all those susceptible should be vaccinated for hepatitis B. Read Full Article.
Roche Files for Application with FDA to Market Leading Hepatitis
C Medication Pegasys(R) for Chronic Hepatitis B Treatment
July 26, 2004- Roche announced today the submission of a supplemental new biologics license application (sBLA) with the U.S. Food and Drug Administration to market Pegasys® (peginterferon alfa-2a) for the treatment of chronic hepatitis B (CHB). Simultaneously, Roche has also filed with the European Medicines Agency to market Pegasys for this indication in the European Union. Pegasys received FDA approval for the treatment of chronic hepatitis C in October 2002 and today is the most prescribed chronic hepatitis C medication in the U.S. "Hepatitis B is a serious public health threat worldwide and can be deadly if left untreated," said Salvatore Badalamente, M.D., Medical Director, Roche. "We are committed to offering Pegasys as a new option to the millions of people throughout the world who are chronically infected with hepatitis B." Read Full Article.
Efficacy of Hepatitis B Vaccination and Interferon Alfa Combination
Therapy Versus Interferon Alfa Monotherapy in Children with Chronic
June 30, 2004- Although interferon (IFN) has been approved in the treatment of chronic hepatitis B in children, it is effective only in 30-40% of this population. In some studies it has been suggested that therapeutic use of anti-hepatitis B virus (HBV) vaccine may be beneficial in patients with chronic hepatitis B. Read Full Article.
HBV and HCV Diagnostic Tests Recalled
July 26, 2004 — The U.S. Food and Drug Administration (FDA) recalled Cobas TaqMan and TaqMan 48 analyzers (made by Roche Molecular Systems, Inc.) on May 24 due to reports of falsely elevated test results, according to an alert sent on Saturday from MedWatch, the FDA's safety information and adverse event reporting program. Read Full Article.
Plant-Derived MAb to HBV Surface Antigen May Provide Treatment
June 23, 2004- Japanese scientists have successfully used transgenic tobacco cells to produce the human monoclonal antibody (MAb) to hepatitis B virus (HBV) surface antigen (HbsAg). This work demonstrates the "feasibility of producing MAbs to HbsAg in plants as an alternative to anti-HBs human immunoglobulins," Dr. Akira Yano from the National Institute of Public Health in Tokyo and colleagues write in the June issue of the Journal of Medical Virology. Read Full Article.
Even With Undetectable Levels, Hep B Persists in Liver With
Chronic Hep C Infection
June 21, 2004- Hepatitis B virus (HBV) can persist in the liver of patients with chronic hepatitis C without detectable hepatitis B virus DNA in serum, according to a report in the June Journal of Medical Virology. "Our data suggest that the overall prevalence of HBV infection is higher than that known at present, since patients may have HVB-DNA in liver without any other viral marker in serum," lead author Dr. Vicente Carreno from Fundacion para el Estudio de las Hepatitis Virales, Madrid, Spain, told Reuters Health. Read Full Article.
Pegylated Interferon Has Primary Role in Treatment of Chronic
June 18, 2004- Studies of 4 to 6 months of treatment with conventional interferon alfa for hepatitis B e antigen (HBeAg)-positive chronic hepatitis B virus (HBV) infection have shown clearance of HBeAg to be higher in treated patients than it is in controls by approximately 25%. These results are considerably better than those from studies of antiviral agents. Read Full Article.
Unusual Cases of HBV Transmission
June 2004- IAC published an education piece titled "Unusual Cases
of Hepatitis B Virus Transmission." This piece replaces the 1994
article "No Risk?? No Way!!" The updated document may be useful to both health professionals and selected members of the public. It was developed to respond to parents who question the necessity of vaccinating infants against HBV [hepatitis B virus] because they believe that only sexually promiscuous persons or drug users could ever become infected with the virus. The piece presents 21 scenarios of HBV transmission via medical procedures, team sports, day care, school, and more. All cases were reported in peer-reviewed journals and citations are provided. "Unusual Cases of Hepatitis B Virus Transmission" is available in ready-to-copy (PDF) format at www.immunize.org/catg.d/p2100nrs.pdf
Telbivudine, a Promising Experimental HBV-specific L-nucleoside
June 2, 2004- The L-nucleoside telbivudine (LdT) is an investigational new drug for the treatment of chronic hepatitis B. This report highlights the current evidence for the efficacy and safety of this promising antiviral agent. Data from both pre-clinical studies and randomized controlled clinical trials are reviewed. Read Full Article.
Tolerance of Interferon Alfa Therapy in Children with Chronic
May 26, 2004- The objective of the current study was to assess the side effects of interferon alfa (IFN-a) therapy in children with chronic hepatitis B. This prospective study was performed on 100 children by interviewing the patients and their parents; clinical examinations and laboratory investigations were performed during and after therapy. Read Full Article.
High Viral Load is a Risk Factor for Hepatocellular Carcinoma
in Patients With Chronic Hepatitis B Virus Infection
May 24, 2004- How does the serum level of HBV-DNA correlate with progression of the disease? What is the relationship between the level of HBV-DNA and hepatocarcinogenesis in patients with chronic HBV? [J Gastroenterol Hepatol 19(6) 2004] Read the Full Article.
Coffee, Caffeine Consumption Associated With Reduced Liver
May 21, 2004- A U.S. population study of 5,944 adults conducted by researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has found a strong association between coffee drinking and caffeine consumption and a lower risk of liver injury in persons at high risk for liver disease. Read Full Article.
Among Children Who Were Nonresponders to Interferon, One Year
Treatment with Lamivudine Provided Benefits
April 30, 2004- Data regarding the effect of extended lamivudine (Epivir-HBV) treatment in children who failed to respond to previous IFN alfa therapy are scarce. Therefore, the effects of lamivudine treatment on ALT activity, HBV DNA and HBeAg seroconversion as well as the occurence of YMDD mutant and adverse effects were determined. Read Full Article.
Readily Obtainable Data Can Predict Inflammation and Fibrosis
in Patients with Chronic HBV and May Remove the Need for Liver Biopsies
in Some Patients
April 28, 2004- Histologic activity index (HAI) has been shown to correlate with antiviral response in patients with chronic hepatitis B (CHB) and fibrosis determines the urgency of treatment. The objective of the current study was to develop models using readily available objective data to predict inflammation and fibrosis in patients with CHB. Read Full Article.