3. How many people have chronic hepatitis B?
The large amount of carriers, most of whom are in Asia, the
large number of deaths per year. There are 1.25 million carriers in the US, or
0.3% of the adult population as I alluded to. Now compare this to hepatitis C, hepatitis C
is 4 million adults in America and about 2% of adult Americans, so
hepatitis C gets a lot more of the press but we’re working on that to
try to get more of the press interested in realizing that hepatitis B
also is a major infection in the United States. The real concern is the premature mortality
from cirrhosis or HCC (the
abbreviation for hepatocellular carcinoma) liver cancer, that also
goes by the name "hepatoma", and that ranges from 15% to 40%, or
roughly a quarter of the people with chronic hepatitis B. This is in
particular people who are infected early in life. We’re a little less knowledgeable about
people who are Caucasian Americans infected in their adolescence or
early adult life about whether these same kind of statistics really
2. What is the prevalence rate of chronic hepatitis B in the world?
4. What is the natural history and progression of hepatitis B?